We are looking for a postdoctoral scientist to work on challenging and exciting neuroproteomics problems. Close collaboration with @coscialab.bsky.social Apply: jobs.helmholtz-hzi.de/job/Braunsch...

Excited to share our new @natcomms.nature.com study with the @garyrlewin.bsky.social lab and @amapruns.bsky.social. Using deep visual proteomics, we created the first neuronal subset-resolved proteomic map of sensory neurons with potential implications for pain treatment. go.nature.com/481nr4R

Where are the women’s health drugs? www.nature.com/articles/d41... Wendy Young, an advisor at Google Ventures and former head of small-molecule drug discovery at Genentech, discusses the dearth of women’s health drug discovery programmes

Are you curious about “pain resilience” genes and how to become a successful scientist in the pain field? Listen to the newest episode of the IASP-PRF podcast, featuring Stephen Waxman bit.ly/4sZYorv #PRF #podcast #neuroscience #pain

The LMB is proud to launch the Career Returner Fellowship, a three-year, fully funded postdoc placement for scientists who have had a career break of over 1 year. Applications are open now! More details: mrclmb.ac.uk/careers-and-... Please share this post with anyone who may be interested!

Congrats to Jobert, Anna-Leigh, and Kai on showing how #BDNF amplifies #transcription, coordinates #RNA dynamics, and spatially regulates the #phosphoproteome. Beautiful cover art too! @jamessleigh.bsky.social @frattalab.bsky.social @uclqsion.bsky.social

Mapping nerves in a whole embryos. We find that across species and development stages, embryonic nerves display (beautiful) fractal geometry. More here: www.biorxiv.org/content/10.6...

We have an exciting opportunity at Wolfson SPaRC for a Postdoctoral Research Associate to join our work on the neurobiology of arthritis pain. A great role for researchers interested in neuroscience, advanced imaging, and collaborative science! www.kcl.ac.uk/jobs/142825-...

I just published Don’t Perish! A Step-by-Step Guide to Writing a Scientific Paper (2026 edition) Great science deserves to be read—not buried under unclear writing. This is the updated 2026 edition of your favorite guide to writing scientific papers. medium.com/p/dont-peris...

I was interviewed by @katiepickup.bsky.social recently for @dmmjournal.bsky.social. This has a little bit of my background, a little bit on science and mentoring, and a little bit (ok, more than a little bit) on funding in science. Check it out at: journals.biologists.com/dmm/article/...

IN THIS ECONOMY???

Point of View: An easy way to improve lab meetings doi.org/10.7554/eLif... I'm really happy to see this one out @elife.bsky.social. Awesome Cara Glynn and I describe and reflect on a year-long, low-cost practice that transformed our group meetings. #researchculture #ECR #labmeetings

Blinding samples for a collaborator will always make me think of this 🥕🎁🤔 m.youtube.com/watch?v=0UGu...

A great #PaimResearch listen for all voltage-gated sodium channel fans 😃👇

In Figure 2 we describe how we would propose triaging non-coding variants (NCVs), as a step towards generating evidence supporting pathogenicity and disease causation, currently not addressed in clinical genomic diagnostics.

🔎 Browse extensive libraries of protein structures in Jalview using the 3D Beacons Network. Once imported, these can be colored, superimposed and viewed in 3D in conjunction with alignments. 👓 Synced views provide precision and clarity, allowing you to hone in on regions of importance.

🦴 Living with arthritis pain? We’re starting a new project on arthritis pain and want to learn from your experience. 👉 Which movements trigger or worsen your pain? Please take a few minutes to complete our short survey: forms.office.com/e/qv0tx9LJ1L Your input will help guide our research.

academic.oup.com/genetics/adv... Also thanks to Lyndall & @psarkies.bsky.social, @ahocher.bsky.social, and members of the lab for their comments and Francis Barr @oxfordbiochemistry.bsky.social for encouraging me to write down my thoughts. 2/2

9pm Switzerland time, y'all! I'll be talking about how neurons are like onions. Tiny onions. Sort of. Look, you'll have to be there 🧪🧅🐟

A welcome and much needed reopening of pplicant-led grants today at MRC, with no closing date. It brings massive changes to assessment, with more details now available. Focus is on evaluation by a "college of experts" but its composition is still not clear. 1/6 www.ukri.org/opportunity/...

You have more in common with the people of Iran than you do with anyone in this administration, any member of the technocracy, anyone who is profiting from this war, or any billionaire. When you see Iranians forming human chains outside key infrastructure sites, you should feel a sense of kinship.

We should all do our part to join Brian in ending genetics essentialism. I give a lecture at Pitt to the new PhD students entitled "There is no such thing as wild-type." I blogged about this years ago and it's part of my teaching statement. Long road, team effort✊🏻 micropopbio.org/blog/2018-07...

I hope this isn’t the end of Brian’s career but if there’s something people can do, it’s use his material in your classes (thankfully carried on by @robbeewedow.bsky.social and company)

Thankful to Brian and his team for doing this important work, then giving clear and actionable advice: www.cell.com/hgg-advances... link.springer.com/article/10.1...

20% of British electricity coming from solar power at six in the evening in early April is absolutely remarkable. And we’re just getting started…🇬🇧♻️⚡️💡🔋😎

I am INCREDIBLY proud to share our lab’s first preprint, after 22 months of work! A result of Dr. Anna Schreiber @annaschreiber.bsky.social and Dr. Anamika Gupta’s fantastic work, we focus on an ultra rare developmental disease, YWHAG syndrome. (1/?) www.biorxiv.org/content/10.6...

Did you take a career break of at least one year, perhaps to start a family, take care of a loved one, or for any other reason? Come and join the @mrclmb.ac.uk through this targeted fellowship, and discover the many more ways in which this is such a special place to work. 🤗

#BlackInNeuro, #BlackInSTEM? Heads up that this fantastic postdoc opportunity opens for applications this month (closing date 17th May). Come and join us at @mrclmb.ac.uk! mrclmb.ac.uk/careers-and-...

I'm so pleased to see this work on neural crest development out in Nature today! This was a truly fantastic collaboration with @gleesonlab.bsky.social, Keng loi (Harry) Vong and @xiaoxuyang.bsky.social. Huge thanks to everyone involved 👏 🧪🐣 #devbio www.nature.com/articles/s41...

In a study published today in Nature (rdcu.be/fbf5Q), we described the developmental organization of sensory and sympathetic ganglia in multiple organisms. Huge thanks to the great contribution from @gleesonlab.bsky.social , Keng Ioi (Harry) Vong, @melaniedwhite.bsky.social, and all collaborators!

A question I get asked all the time by @dev-journal.bsky.social authors "Why does it cost so much to publish a paper?" We break down the finances and explain where the money goes Spoiler: quality publishing takes a village (people + infrastructure) journals.biologists.com/dev/article/...

My main gripe with the alphafold example is how it shows you need decades and decades of high quality data, well structured, open and accessible to train a model -- and yet they always gloss over it and pretend it's just AI and magic. No, we need to continuously invest in real data and FAIR data.

BOOM! Major advance on unanswered questions on Nav1.7 in hDRG from Bruce Bean and team www.biorxiv.org/content/10.6...

Another banger from my UCSF/Genentech Hall colleagues Yifan Cheng and David Julius! www.nature.com/articles/s41...

I defended my PhD 10 years ago today. That was the least remarkable thing that happened that day. Sharing something I wrote about it last year. Since then "the horrors persist but so do we." And with dignity.

Establishing a commercial solution for extremely rare genetic diseases go.nature.com/4aHSIvu

Holy moly this is cool! Ex vivo prep of a human sensory neuron and spinal cord circuit, used for studying Nav1.8 and CGRP activity.

Well done. Every news outlet should run a piece like this. By my age, you will have lost someone to cancer. Or cardiovascular disease. Or another disease NIH funding combats. You will wish you had more time with them. That’s what NIH funding does. Buys us time with the people we love. #FundNIH.

I'm always amazed by the complexity and nuance of the neuroscience of pain. In this Perspective, @simonbeggslab.bsky.social and @franklandlab.bsky.social do a great job of explaining some important new findings on the role of time in the mechanisms of chronic pain www.science.org/doi/10.1126/...

Well some of us are. Many top neuro journals straight up desk reject model organism papers nowadays. And if you want to get fast, detailed and precise mechanistic answers - some of these are still the best systems.

what sequencing-based strategy do people like to look at CRISPR/cas9 editing in a polyclonal cell population? in the past i have used Sanger+the TIDE algorithm. I know some labs amplify the target region and do NGS- if that option, what company would you use? any other options?

I wrote a short piece on what funding and hiring committees often overlook when assessing merit. @academic-chatter.bsky.social

Two decades of induced pluripotent stem cell research: From discovery to diverse applications

Pain may be more than a symptom in breast cancer, a new study says. Nerves that sense pain can release chemicals that help tumors grow and spread. Read on: bit.ly/472BTJA @vivtawfik-mdphd.bsky.social

Every day is a good day for sharing one of the most useful papers about research data ever written. PLEASE get your people to understand and follow this advice. www.tandfonline.com/doi/full/10....

Induced proximity-based therapeutic modalities www.nature.com/articles/s41... rdcu.be/e8CrR This Review in the March issue covers the range of therapeutic modalties that act by inducing interactions between biomolecules, including molecular glues and bifunctional molecules

Minus the croissant metaphor, which is brilliant, this is the strategy I always use when I give scientific talks regardless of audience.

This, to me, is the true creeping horror of AI - not that it may gain personhood, but that we are so eager to take advantage of its benefits that we will sacrifice our own and that of our trainees. Yes, it is *faster* to write a proposal with AI, in that doing so “frees” us of human collaboration.

Paid 12-month internship: Communications Officer. We have an exciting opportunity for someone looking to take their first step into a science communication or publishing role. Based Cambridge, UK (& wfh). See the full role description for further details at biologists.com/wp-content/u...

Thought-provoking read.