Subhojit Roy MD, PhD
@roylab-ucsd.bsky.social
š¤ 321
š„ 237
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Science & Music. Sometimes funny. www.roylab.org
https://www.youtube.com/@pandemicmelodica
reposted by
Subhojit Roy MD, PhD
Journal of Cell Science
about 18 hours ago
Why is publishing so expensive? In this Editorial, we (
@katherine-brown.bsky.social
@drmichaelway.bsky.social
&
@seemagrewal.bsky.social
) provide details and context on JCS's finances, and hope to dispel some of the myths around the economics of publishing.
journals.biologists.com/jcs/article/...
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BIGGEST problem in
#science
peer review (wasting massive time/$$): Say you created device that prevents dogs from wagging tail (novel, lets say works, ?utility). Rev #1: "This is all good but does it work in Pekingese poodles?". Why, because he has one. Guess what Editor agrees...she has one too!
about 7 hours ago
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I'm not getting this go around the moon and come back home thing. If we are doing the 70s again lets bring back disco.
1 day ago
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"[A] way to reduce the effects of news overwhelm is to unplug from the news"
www.nature.com/articles/d41...
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Struggling to focus on research when the world is āon fireā? Some ways to cope
Keeping up with distressing news is affecting some researchersā mental health and their scientific work.
https://www.nature.com/articles/d41586-026-00264-x
1 day ago
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reposted by
Subhojit Roy MD, PhD
SfN Journals
2 days ago
#JNeurosci
: In this work, Tumminia, Mezache,
@christlet.bsky.social
et al. have developed a new method to induce the formation of synapses along axons directly on the glass coverslip rather than in contact with another neuron.
https://doi.org/10.1523/JNEUROSCI.1741-24.2026
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Great video to help set up your Biosketch in SciENcv
www.youtube.com/watch?v=lThi...
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Biosketch Set Up in SciENcv
YouTube video by Duke University Medical Center Library & Archives
https://www.youtube.com/watch?v=lThiS2KyBS0
3 days ago
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reposted by
Subhojit Roy MD, PhD
Michael Ward
5 days ago
Excited to share a pre-print from a collaboration between my lab at NIH, Len Petrucelli's lab at University of Miami, and Shyamal Mosalaganti's lab at University of Michigan.
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I was at a barbershop this morning where the guy said his mother and sister think all scientists are hiding information ("there IS a cure for cancer!!"). I gave him a 20 min lecture on the joys of peer review. Jokes aside surprising how little people know about the scientific process.
7 days ago
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@juanbonifacino.bsky.social
...about time!
add a skeleton here at some point
7 days ago
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reposted by
Subhojit Roy MD, PhD
American Society for Cell Biology
8 days ago
No advocacy experience needed. ASCB provides training and support for members participating in the Texas Virtual Capitol Hill Day on April 22. Register:
https://www.ascb.org/ascb-meetings/ascb-texas-virtual-capitol-hill-day-2/
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ASCB Texas Virtual Capitol Hill Day - ASCB
Texas ASCB members can meet with their elected officials to educate them about the federally funded research in Texas.
https://www.ascb.org/ascb-meetings/ascb-texas-virtual-capitol-hill-day-2/
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"Its more of a comment than a question"
8 days ago
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Our lab has an open postdoctoral position. Work in the lab ranges from trafficking of neuronal cargoes to developing gene editing therapeutics for Alzheimer's and Parkinson's. I'm looking for the right person, project is flexible. Please apply immediately.
www.roylab.org
9 days ago
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In case you didn't know this....don't use mitotracker lol.
www.cell.com/cell-reports...
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MitoTracker transfers from astrocytes to neurons independently of mitochondria
The mitochondrial dye MitoTracker is commonly used to investigate intercellular mitochondrial transfer (IMT), particularly between astrocytes and neurons. Hole et al. compare MitoTracker with a geneti...
https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(26)00038-X
14 days ago
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Seen at our local Indian store in
#SanDiego
. I don't think Italians know what garlic bread looks like.
16 days ago
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Looking at raw data always reminds me why I chose to do this. Saw some handsome synapses yesterday.
17 days ago
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Sometimes EM shows weird things...what in the name of the Lord is this?
17 days ago
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reposted by
Subhojit Roy MD, PhD
The Company of Biologists
21 days ago
Visit our fully accessible journal archive, providing perpetual access to 34k articles from over a century of pioneering research in developmental biology, cell biology, comparative physiology and biomechanics, including work from 60+ Nobel Prize-winners
bit.ly/3PfIjib
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NIH wants feedback from us lol
21 days ago
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"So letās see what the FDA does now. Thatāll depend on who replaces Vinay Prasad, how much of a loon they are, and how much theyāre willing to make decisions like this"
www.science.org/content/blog...
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A Unique Situation for UniQure
https://www.science.org/content/blog-post/unique-situation-uniqure
22 days ago
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"I wonder if we do not waste most of our energy just by spending every waking minute saying hello to ourselves" Annie Dillard on Unselfconsciousness
www.themarginalian.org/2026/03/07/a...
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Annie Dillard on Unselfconsciousness
Walking through the white-walled gallery at the graduation show of one of New Yorkās most esteemed art schools, between beautiful young people with Instagram faces, I was struck to see projecā¦
https://www.themarginalian.org/2026/03/07/annie-dillard-muskrat/
24 days ago
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reposted by
Subhojit Roy MD, PhD
FocalPlane
29 days ago
š¬š¦In our latest Imaging spotlight, Nicholas Boyer takes us through the key results, & offers some top technical tips, from their research on the axonal membrane-associated periodic skeleton with Rohan Sharma, Christophe Leterrier
@christlet.bsky.social
, Subhojit Roy
@roylab-ucsd.bsky.social
& team.
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Imaging spotlight: the axonal membrane-associated periodic skeleton - FocalPlane
Imaging spotlight: the axonal membrane-associated periodic skeleton - News
https://focalplane.biologists.com/2026/03/05/imaging-spotlight-the-axonal-membrane-associated-periodic-skeleton/
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The what, why, and how of feedback on writing: Its no use telling people WHAT to write (though this is fastest). You must tell them WHY what they wrote is not working, and HOW your changes make it better (open for discussion). Unfortunately, a very painful process for both parties.
29 days ago
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reposted by
Subhojit Roy MD, PhD
NPR
30 days ago
Sydney Peterson is among the U.S. athletes heading to the 2026 Winter Paralympics. A neuroscientist in training, Peterson is studying movement disorders, similar to her own condition.
n.pr/3P0q28t
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As Paralympics approach, U.S. skier Sydney Peterson balances training and research
Sydney Peterson is among the U.S. athletes heading to the 2026 Winter Paralympics. A neuroscientist in training, Peterson is studying movement disorders, similar to her own condition.
https://n.pr/3P0q28t
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āIāve had federal funding in the past, but right now I donāt,ā he says. āTo be honest, Iād be happy to find a rich person, but one with better morals than Jeffrey Epsteinā
www.science.org/content/arti...
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Meet three scientists who said no to Epstein
The warning signs included a web search, a motherās doubts, and inklings of a āsexist attitudeā
https://www.science.org/content/article/meet-three-scientists-who-said-no-epstein
about 1 month ago
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"Thereās a constant background noise of āpromising clinical resultsā stories in the news, but people generally donāt get a chance to see how few of those lead anywhere" The Best Ideas Are Not Always Enough | Science | AAAS
www.science.org/content/blog...
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The Best Ideas Are Not Always Enough
https://www.science.org/content/blog-post/best-ideas-are-not-always-enough
about 1 month ago
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It was fun to be the editor for this one.
add a skeleton here at some point
about 1 month ago
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LLPS in Chinese Fish soup
about 1 month ago
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Since grad school interviews are happening, here's some things you should probably not say to the faculty interviewer: - "why don't you tell me a little bit about your research?" - "yeah yeah yeah...I've seen it all, know what y're sayin'..." - "UCSD is ok, but really.." - "so...who's your PI?"
about 1 month ago
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"But most faculty seem to view the academic hierarchy as some kind of natural law, where they are knowledge producers and staff are knowledge supporters"
www.science.org/content/arti...
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Staff scientists shouldnāt feel invisible. We deserve more voice
āI felt valued but not included,ā this staff scientist writes
https://www.science.org/content/article/staff-scientists-shouldn-t-feel-invisible-we-deserve-more-voice
about 2 months ago
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Often when I find no answers to a question, it turns out to be the wrong question.
about 2 months ago
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youtu.be/NaXFEBNhpSM?...
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Pyaar Do Pyaar Lo (Jaanbaaz 1986) #bollywood #synthpop #kalyanjianandji #sapnamukherjee #melodica
YouTube video by Pandemic Melodica
https://youtu.be/NaXFEBNhpSM?si=IKSeERMJy02ysi8y
about 2 months ago
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Cotton wool Abeta plaque
about 2 months ago
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"My studentās feedback prompted me to think why I pursued career in academia in first place. I recalled the excitement I felt as a postdoc, when curiosity was king for me...I lost sight of this when I was consumed by problems and fears under the tenure clock"
www.science.org/content/arti...
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I needed a culture shift in my lab. Iām grateful one student spoke up
āI was transferring the stress I was under onto my graduate students,ā this professor writes
https://www.science.org/content/article/i-needed-culture-shift-my-lab-i-m-grateful-one-student-spoke
2 months ago
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"What I wish for now is no longer happiness but simply awareness⦠I hold onto the world with every gesture, to men with all my gratitude and pity"
share.google/Jf3cKGPKY9mr...
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Albert Camus on How to Live Whole in a Broken World
Born into a World War to live through another, Albert Camus (November 7, 1913āJanuary 4, 1960) died in a car crash with an unused train ticket to the same destination in his pocket. Just threā¦
https://share.google/Jf3cKGPKY9mrjEPZS
2 months ago
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"I might not have felt the need to step away from academia had we aimed for a lower impact journal...success isnāt solely a matter of high-impact papers...its tracing a path that isnāt defined by what others expect of me"
www.science.org/content/arti...
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How chasing a high-impact publication nearly broke me
āLooking back, Iām not sure it was worth the sacrifice,ā this scientist writes
https://www.science.org/content/article/how-chasing-high-impact-publication-nearly-broke-me
2 months ago
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"His groundbreaking work was not the result of mythical serendipity alone, but rather the culmination of perseverance, intellect and a willingness to think differently from the heart of a colonial world"
aeon.co/essays/why-s...
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Why Satyendra Nath Bose was more than Einsteinās sidekick | Aeon Essays
The life of Indian physicist Satyendra Nath Bose illuminates how scientific genius can emerge from the most unexpected quarters
https://aeon.co/essays/why-satyendra-nath-bose-was-more-than-einsteins-sidekick?utm_source=Aeon+Newsletter&utm_campaign=82ca548bde-EMAIL_CAMPAIGN_2026_01_23&utm_medium=email&utm_term=0_-62b901ec41-68688273
2 months ago
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The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine
www.nytimes.com/interactive/...
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The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine
A quiet policy change means the government is making fewer bets on long-term science.
https://www.nytimes.com/interactive/2025/12/02/upshot/trump-science-funding-cuts.html?smid=bs-share
2 months ago
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reposted by
Subhojit Roy MD, PhD
Needhi Bhalla š š½
2 months ago
the original language in the Senate appropriations bill kept the MYF policy to 2024 levels ask your congressional representatives for the current language in the funding bill to be replaced with this language: keep MYF at 2024 levels, NOT 2025 levels š§Ŗ
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reposted by
Subhojit Roy MD, PhD
Needhi Bhalla š š½
2 months ago
The NIH's MYF policy in 2025 resulted in 4000 fewer grants and fellowships that touched every area of biology and medicine; continuing it in 2026 would be disastrous for science, technology and health in the United States š§Ŗ
www.nytimes.com/interactive/...
add a skeleton here at some point
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"The first is the pleasure in having the initial idea or insight. The insight could be asking a new question or finding a new answer; there is surprisingly not much difference...in either case, the essential event is a shift of perspective..."
journals.biologists.com/jcs/article/...
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Why would anyone want to be a scientist?
It is difficult to fathom why anyone intelligent enough to be a scientist would actually choose to be one. Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently...
https://journals.biologists.com/jcs/article/138/15/jcs264284/368759/Why-would-anyone-want-to-be-a-scientist
3 months ago
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Clock in and Clock out to make new discoveries and improve human health. Simple.
3 months ago
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Annie Dillard in An American Childhood. All great writers are ultimately Yogis.
3 months ago
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Full pdf
@cp-iscience.bsky.social
collab w/
@christlet.bsky.social
www.cell.com/action/showP...
I may go down ya'll but this was the best thing I wrote: DECLARATION OF GENERATIVE AI AND AI-ASSISTED TECHNOLOGIES IN THE WRITING PROCESS "No AI/AI-assisted tools were used in the writing process"
3 months ago
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"More recently, I've also noticed that trainees don't spend time thinking on their own and only do so when prodded" Didn't want to sound like dad in interview...BUT I think this is due to passive consumption of media. Specifically excessive cell phone usage.
journals.biologists.com/jcs/article/...
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Interview with Journal of Cell Science Editor Subhojit Roy
ABSTRACT. Subhojit Roy is Professor of Pathology at the University of California San Diego (UCSD) in the USA. Subhojit completed his MD in Kolkata, India and then moved to Temple University in Philade...
https://journals.biologists.com/jcs/article/138/22/jcs264518/369878/Interview-with-Journal-of-Cell-Science-Editor
3 months ago
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American author Joan Didion once said: āI write entirely to find out what I am thinking.ā What happens when we stop writing? Do we stop finding out?
www.theguardian.com/commentisfre...
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Our king, priest and feudal lord ā how AI is taking us back to the dark ages | Joseph de Weck
Since the Enlightenment, weāve been making our own decisions. But now AI may be about to change that, says Joseph de Weck, a fellow with the Foreign Policy Research Institute
https://www.theguardian.com/commentisfree/2025/dec/26/ai-dark-ages-enlightenment
3 months ago
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Looking forward to #2026
3 months ago
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āOne discovers the light in darkness, that is what darkness is for; but everything in our lives depends on how we bear the light,ā James Baldwin
@themarginalian.org.web.brid.gy
www.themarginalian.org/2023/09/28/i...
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I Touched the Sun: A Tender Illustrated Fable About How to Find and Bear Your Inner Light
āOne discovers the light in darkness, that is what darkness is for; but everything in our lives depends on how we bear the light,ā James Baldwin wrote in one of his finest, least known ā¦
https://www.themarginalian.org/2023/09/28/i-touched-the-sun-leah-hayes/
3 months ago
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How does the axonal sub-membrane periodic cytoskeleton develop? Nick & Rohan from our lab found that building blocks are delivered in packets and co-assemble locally with actin for final structure. Fun collaboration with imaging Guru
@christlet.bsky.social
and his team.
www.cell.com/iscience/ful...
add a skeleton here at some point
3 months ago
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I was in Bondi beach about this time last year...
4 months ago
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"The gene therapy was previously licensed by Orchard Therapeutics which stopped work in 2022 to save cash amid layoffs. Itās one of the many gene therapies abandoned by industry even with promising clinical data because they may not be profitable" New paradigm?
endpoints.news/in-a-first-f...
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In a first, FDA approves a gene therapy from a nonprofit
The FDA on Tuesday approved Waskyra for a rare immune disease called Wiskott-Aldrich syndrome, for which patients have little options besides a bone marrow transplant.
https://endpoints.news/in-a-first-fda-approves-a-gene-therapy-from-a-nonprofit/
4 months ago
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