Subhojit Roy MD, PhD
@roylab-ucsd.bsky.social
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Science & Music. Sometimes funny. www.roylab.org
https://www.youtube.com/@pandemicmelodica
"Over the last 7ā yrs, we published >700 āFirst Personā interviews...But JCS has been around much longer ā in fact, JCS was first established in 1853 as the Quarterly Journal of Microscopical Science (QJMS), re-branded as JCS in 1966"
@jcellsci.bsky.social
journals.biologists.com/jcs/article/...
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āFirst Personsā through the decades ā 100ā years of notable scientists in Journal of Cell Science
Summary: JCS highlights the lives and careers of 10 notable scientists from around the world who published first author papers in our journal over the last 100ā years.
https://journals.biologists.com/jcs/article/138/17/jcs264351/369118/First-Persons-through-the-decades-100-years-of
4 days ago
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"Intellia Therapeutics announced that its systemic CRISPRāCas9 gene editing medicine had met primary and secondary endpoints, leading the biotech to start a rolling submission for US Food and Drug Administration approval"
www.nature.com/articles/s41...
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Intellia heads to FDA with first in vivo CRISPR-based gene editing therapy - Nature Biotechnology
Nature Biotechnology - Intellia heads to FDA with first in vivo CRISPR-based gene editing therapy
https://www.nature.com/articles/s41587-026-03154-9
9 days ago
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youtu.be/AgMdaeilxC4?...
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Nadiya Chale Chale re Dhaara (Manna Dey in EDM) #mannadey #synth #kalyanjianandji #melodicacover
YouTube video by Pandemic Melodica
https://youtu.be/AgMdaeilxC4?si=8f5l1tqD_vEqH6Ts
11 days ago
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"They are, after all, what our society is. A society in which it is commonplace to discriminate and other people based on religion, region, caste, class, colour of skin, gender and sexuality"
www.espncricinfo.com/story/ipl-20...
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Arshdeep calling Tilak 'andhera' is colourism and it is a problem, not banter
The BCCI, the IPL and the teams are supposed to check this and make the sport a more inclusive space
https://www.espncricinfo.com/story/ipl-2026-arshdeep-singh-calling-tilak-varma-andhera-is-colourism-and-it-is-a-problem-not-banter-1537034
12 days ago
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reposted by
Subhojit Roy MD, PhD
Christophe š¬ Leterrier
18 days ago
I was interviewed by
@snehakhedkar.bsky.social
for The Scientist about our work using super-resolution microscopy to map the neuronal architecture, and make nice pictures along the way! Check the article here:
www.the-scientist.com/super-resolu...
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Super-Resolution Microscopy Helps Map Hidden Neuronal Architecture | The Scientist
Christophe Leterrier uses advanced microscopy to uncover neuronsā intricate nanostructure and dynamics while creating striking images that bring brain science to life.
https://www.the-scientist.com/super-resolution-microscopy-helps-map-hidden-neuronal-architecture-74441
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Our postdoctoral fellow Patrick Kearney, PhD
@ucsandiego.bsky.social
has been selected in the Inaugural Cohort of Discovery Fellows by Aligning Science Across Parkinsonās
@asapresearch.parkinsonsroadmap.org
(full fellowship + research funds):
parkinsonsroadmap.org/newsroom/dis...
23 days ago
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Someone decided THIS is what was missing
@ucsandiego.bsky.social
28 days ago
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reposted by
Subhojit Roy MD, PhD
Amar Sahay
about 1 month ago
The therapy, made by Intellia Therapeutics, uses CRISPR to inactivate that contributes to disfiguring and dangerous swelling attacks in people with hereditary angioedema. The one-time infusion reduced those attacks by 87% compared to placebo
endpoints.news/intellias-in...
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Intellia's in vivo CRISPR therapy first to succeed in Phase 3
An experimental treatment that uses CRISPR to edit genes directly inside the body has just succeeded in a Phase 3 trial, a first for the technology that puts it on track for a potential FDA approval i...
https://endpoints.news/intellias-in-vivo-crispr-therapy-first-to-succeed-in-phase-3/
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Interesting!
add a skeleton here at some point
about 1 month ago
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A high point of the roof at my parents house in
#kolkata
are the
#trains
that pass below...š
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about 1 month ago
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reposted by
Subhojit Roy MD, PhD
Journal of Cell Science
about 1 month ago
Issue 7 is complete Explore our Toc:
journals.biologists.com/jcs/issue/13...
Our cover image is an UExM image of tubulin-based structures during the early stages of Toxoplasma gondii daughter cell formation. See article from Sladewski and Heaslip:
journals.biologists.com/jcs/article/...
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Post apocalyptic to Bordello inspired...all in one
#Kolkata
street
about 1 month ago
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reposted by
Subhojit Roy MD, PhD
There is still time to apply. I'm now looking for someone who likes imaging, for a project like this:
www.cell.com/neuron/fullt...
add a skeleton here at some point
about 1 month ago
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It's not hard to see why the average Englishman posted in East India Company
#kolkata
only lived a few months.
about 1 month ago
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Golgi was right about this but wrong about the synapse and fought until the end with Cajal that it was all continuous and there was no synapse (gap). Ironically Cajal used Golgi's staining method to define synapses in multiple brain circuits.
add a skeleton here at some point
about 1 month ago
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There is still time to apply. I'm now looking for someone who likes imaging, for a project like this:
www.cell.com/neuron/fullt...
add a skeleton here at some point
about 1 month ago
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reposted by
Subhojit Roy MD, PhD
Dave Weisman
about 1 month ago
The methods betray a motivation to dilute positive studies with negative ones. We've seen this in the past as a pathetic attempt to dismiss the efficacy of these drugs.
www.nytimes.com/2026/04/15/h...
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Analysis of Alzheimerās Drugs Stirs Debate About Their Effectiveness
https://www.nytimes.com/2026/04/15/health/alzheimers-drugs-benefit-anti-amyloid.html?smid=bs-share
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reposted by
Subhojit Roy MD, PhD
Journal of Cell Science
about 1 month ago
Why choose JCS? - FREE to publish (with OA options available) - Fast-track option for papers with reports - Submissions handled by Academic Editors - Published by a not-for-profit publisher - A tree planted for every peer-reviewed articleš³ Find out more at:
journals.biologists.com/jcs/pages/re...
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We know why some trials worked and others didn't (time of intervention for ex). You can't combine all of them LOL. It's like averaging results of every exam you ever took and conclude you aren't the topper.
www.cochranelibrary.com/cdsr/doi/10....
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Amyloidābetaātargeting monoclonal antibodies for people with mild cognitive impairment or mild dementia due to Alzheimerās disease - Nonino, F - 2026 | Cochrane Library
Select your preferred language for Cochrane reviews and other content. Sections without translation will be in English.
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD016297/full
about 1 month ago
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#Kolkata
in the rain is really something
@m1singh.bsky.social
about 1 month ago
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The Ideal Postdoc (from Indian comic Amar Chitra Katha)
about 1 month ago
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Reminder that countries following self interest is not new...half of the world was tortured for centuries because Europeans couldn't get cheap spices.
about 1 month ago
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medium.com/@ahintze_232...
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Artemis II: I Am Not Feeling It
The Artemis II splashdown showed up in my feed. Four humans had just traveled farther from Earth than anyone ever had, looped around theā¦
https://medium.com/@ahintze_23208/artemis-ii-i-am-not-feeling-it-f393746ca263
about 2 months ago
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China...
add a skeleton here at some point
about 2 months ago
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reposted by
Subhojit Roy MD, PhD
Journal of Cell Science
about 2 months ago
Why is publishing so expensive? In this Editorial, we (
@katherine-brown.bsky.social
@drmichaelway.bsky.social
&
@seemagrewal.bsky.social
) provide details and context on JCS's finances, and hope to dispel some of the myths around the economics of publishing.
journals.biologists.com/jcs/article/...
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BIGGEST problem in
#science
peer review (wasting massive time/$$): Say you created device that prevents dogs from wagging tail (novel, lets say works, ?utility). Rev #1: "This is all good but does it work in Pekingese poodles?". Why, because he has one. Guess what Editor agrees...she has one too!
about 2 months ago
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I'm not getting this go around the moon and come back home thing. If we are doing the 70s again lets bring back disco.
about 2 months ago
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"[A] way to reduce the effects of news overwhelm is to unplug from the news"
www.nature.com/articles/d41...
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Struggling to focus on research when the world is āon fireā? Some ways to cope
Keeping up with distressing news is affecting some researchersā mental health and their scientific work.
https://www.nature.com/articles/d41586-026-00264-x
about 2 months ago
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reposted by
Subhojit Roy MD, PhD
SfN Journals
about 2 months ago
#JNeurosci
: In this work, Tumminia, Mezache,
@christlet.bsky.social
et al. have developed a new method to induce the formation of synapses along axons directly on the glass coverslip rather than in contact with another neuron.
https://doi.org/10.1523/JNEUROSCI.1741-24.2026
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Great video to help set up your Biosketch in SciENcv
www.youtube.com/watch?v=lThi...
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Biosketch Set Up in SciENcv
YouTube video by Duke University Medical Center Library & Archives
https://www.youtube.com/watch?v=lThiS2KyBS0
about 2 months ago
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reposted by
Subhojit Roy MD, PhD
Michael Ward
2 months ago
Excited to share a pre-print from a collaboration between my lab at NIH, Len Petrucelli's lab at University of Miami, and Shyamal Mosalaganti's lab at University of Michigan.
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I was at a barbershop this morning where the guy said his mother and sister think all scientists are hiding information ("there IS a cure for cancer!!"). I gave him a 20 min lecture on the joys of peer review. Jokes aside surprising how little people know about the scientific process.
2 months ago
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@juanbonifacino.bsky.social
...about time!
add a skeleton here at some point
2 months ago
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reposted by
Subhojit Roy MD, PhD
American Society for Cell Biology
2 months ago
No advocacy experience needed. ASCB provides training and support for members participating in the Texas Virtual Capitol Hill Day on April 22. Register:
https://www.ascb.org/ascb-meetings/ascb-texas-virtual-capitol-hill-day-2/
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ASCB Texas Virtual Capitol Hill Day - ASCB
Texas ASCB members can meet with their elected officials to educate them about the federally funded research in Texas.
https://www.ascb.org/ascb-meetings/ascb-texas-virtual-capitol-hill-day-2/
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"Its more of a comment than a question"
2 months ago
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Our lab has an open postdoctoral position. Work in the lab ranges from trafficking of neuronal cargoes to developing gene editing therapeutics for Alzheimer's and Parkinson's. I'm looking for the right person, project is flexible. Please apply immediately.
www.roylab.org
2 months ago
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In case you didn't know this....don't use mitotracker lol.
www.cell.com/cell-reports...
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MitoTracker transfers from astrocytes to neurons independently of mitochondria
The mitochondrial dye MitoTracker is commonly used to investigate intercellular mitochondrial transfer (IMT), particularly between astrocytes and neurons. Hole et al. compare MitoTracker with a geneti...
https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(26)00038-X
2 months ago
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Seen at our local Indian store in
#SanDiego
. I don't think Italians know what garlic bread looks like.
2 months ago
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Looking at raw data always reminds me why I chose to do this. Saw some handsome synapses yesterday.
2 months ago
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Sometimes EM shows weird things...what in the name of the Lord is this?
2 months ago
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reposted by
Subhojit Roy MD, PhD
The Company of Biologists
3 months ago
Visit our fully accessible journal archive, providing perpetual access to 34k articles from over a century of pioneering research in developmental biology, cell biology, comparative physiology and biomechanics, including work from 60+ Nobel Prize-winners
bit.ly/3PfIjib
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NIH wants feedback from us lol
3 months ago
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"So letās see what the FDA does now. Thatāll depend on who replaces Vinay Prasad, how much of a loon they are, and how much theyāre willing to make decisions like this"
www.science.org/content/blog...
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A Unique Situation for UniQure
https://www.science.org/content/blog-post/unique-situation-uniqure
3 months ago
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"I wonder if we do not waste most of our energy just by spending every waking minute saying hello to ourselves" Annie Dillard on Unselfconsciousness
www.themarginalian.org/2026/03/07/a...
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Annie Dillard on Unselfconsciousness
Walking through the white-walled gallery at the graduation show of one of New Yorkās most esteemed art schools, between beautiful young people with Instagram faces, I was struck to see projecā¦
https://www.themarginalian.org/2026/03/07/annie-dillard-muskrat/
3 months ago
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reposted by
Subhojit Roy MD, PhD
FocalPlane
3 months ago
š¬š¦In our latest Imaging spotlight, Nicholas Boyer takes us through the key results, & offers some top technical tips, from their research on the axonal membrane-associated periodic skeleton with Rohan Sharma, Christophe Leterrier
@christlet.bsky.social
, Subhojit Roy
@roylab-ucsd.bsky.social
& team.
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Imaging spotlight: the axonal membrane-associated periodic skeleton - FocalPlane
Imaging spotlight: the axonal membrane-associated periodic skeleton - News
https://focalplane.biologists.com/2026/03/05/imaging-spotlight-the-axonal-membrane-associated-periodic-skeleton/
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The what, why, and how of feedback on writing: Its no use telling people WHAT to write (though this is fastest). You must tell them WHY what they wrote is not working, and HOW your changes make it better (open for discussion). Unfortunately, a very painful process for both parties.
3 months ago
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reposted by
Subhojit Roy MD, PhD
NPR
3 months ago
Sydney Peterson is among the U.S. athletes heading to the 2026 Winter Paralympics. A neuroscientist in training, Peterson is studying movement disorders, similar to her own condition.
n.pr/3P0q28t
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As Paralympics approach, U.S. skier Sydney Peterson balances training and research
Sydney Peterson is among the U.S. athletes heading to the 2026 Winter Paralympics. A neuroscientist in training, Peterson is studying movement disorders, similar to her own condition.
https://n.pr/3P0q28t
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āIāve had federal funding in the past, but right now I donāt,ā he says. āTo be honest, Iād be happy to find a rich person, but one with better morals than Jeffrey Epsteinā
www.science.org/content/arti...
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Meet three scientists who said no to Epstein
The warning signs included a web search, a motherās doubts, and inklings of a āsexist attitudeā
https://www.science.org/content/article/meet-three-scientists-who-said-no-epstein
3 months ago
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"Thereās a constant background noise of āpromising clinical resultsā stories in the news, but people generally donāt get a chance to see how few of those lead anywhere" The Best Ideas Are Not Always Enough | Science | AAAS
www.science.org/content/blog...
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The Best Ideas Are Not Always Enough
https://www.science.org/content/blog-post/best-ideas-are-not-always-enough
3 months ago
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It was fun to be the editor for this one.
add a skeleton here at some point
3 months ago
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