Maya Dannawi
@mayadannawi.bsky.social
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Postdoctoral researcher • Sensory neurophysiology/ Pain 🐭🧠 • hiking, books, and music • 🇱🇧 •📍🇬🇧
reposted by
Maya Dannawi
Ewan St. John Smith
about 1 month ago
New pre-print from
@phar.cam.ac.uk
& Bellefroid lab at ULB! Led by
@mayadannawi.bsky.social
w support from
@interlukein.bsky.social
& more! We investigate impact of overexpressing the zinc finger transcriptional regulator Prdm12 on sensory neuron function / joint pain.
#neuroskyence
#PainResearch
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AAV-mediated overexpression of Prdm12 in knee-innervating afferents reduces inflammatory joint pain and neuronal hyperexcitability in mice
Inflammatory joint pain features in numerous musculoskeletal disorders that affect millions globally. The Prdm12 gene encodes a conserved zinc finger transcriptional regulator expressed selectively in...
https://www.biorxiv.org/content/10.1101/2025.10.14.680517v1
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reposted by
Maya Dannawi
Ewan St. John Smith
8 months ago
Today marks a special day in the annual rhythm of the
@corpuscambridge.bsky.social
Chronophage Clock, which you can find in the centre of
#Cambridge
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It was a wonderful experience! A lot of interesting questions!
add a skeleton here at some point
10 months ago
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reposted by
Maya Dannawi
Luke Pattison
11 months ago
Riding the year out on a high ✨ - latest paper out now in
@pnas.org
! ☺️ 🙏 Here we describe a role for the proton-sensing GPCR, GPR65 in mediating joint pain from fibroblast-like synoviocytes!
www.pnas.org/doi/10.1073/...
#PainResearch
#Neuroskyence
More on this work below 👇 🧵 [1/10]
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Activation of the proton-sensing GPCR, GPR65 on fibroblast-like synoviocytes contributes to inflammatory joint pain | PNAS
Inflammation is associated with localized acidosis, however, attributing physiological and pathological roles to proton-sensitive receptors is chal...
https://www.pnas.org/doi/10.1073/pnas.2410653121
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Congratulations Luke!! Perfect news to end the year! 🎉
add a skeleton here at some point
11 months ago
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reposted by
Maya Dannawi
Ewan St. John Smith
12 months ago
Pain = main driver of clinical decision making in osteoarthritis (OA). Our lab studies OA pain mechanisms. During OA, multiple cell-cell interactions occur, many mediators being released that alter the contents of the synovial fluid.
#PainResearch
#Neuroskyence
journals.lww.com/pain/Fulltex...
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