Huge congratulations to Dr Leire Bejarano, an amazing postdoc from our lab, who received the "Young Researcher in Basic Sciences Award" from the Faculty of Biology & Medicine UNIL Super proud of you @lbejarano.bsky.social !! 🎉🥳🤩 @fbm-unil.bsky.social @unil.bsky.social www.unil.ch/news/1749042...

📢ONLINE @natgenet.nature.com 📰A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen. By @mldm.bsky.social, @lbarquist.bsky.social, Mikael E. Sellin and colleagues. ⬇️ www.nature.com/articles/s41...

The whole DIB would like to congratulate Pascal Schneider for his Lifetime Achievement Award! More info: www.unil.ch/news/1749042...

PhDone! 🥳 It has been a pleasure to work in the fantastic @brozlab.bsky.social and celebrate with friends and family! Thanks also to my experts @jelenalab.bsky.social and @veeninglab.com and my president Thierry Roger!

Inflammatory signalling must eventually be turned off (e.g. by feedback inhibition) to prevent chronic inflammation. We didn't know how #inflammasomes turn off their signalling in vivo ... until now! (🧵: 1/3) shorturl.at/8lWxW

Maybe we should honor the women who were real astronauts. From left to right are Shannon W. Lucid, Margaret Rhea Seddon, Kathryn D. Sullivan, Judith A. Resnik, Anna L. Fisher, and Sally K. Ride. NASA selected all six women as their first female astronaut candidates in January 1978.

Most inflammasome mutations in humans are gain of function, which complicates the question of why we have these molecular machines. @sunnyshinlab.bsky.social et al provide strong evidence that we need inflammasomes to prevent Salmonella infection. A must read! elifesciences.org/articles/90107

Thrilled to share our @elife.bsky.social paper "Inflammasomes primarily restrict cytosolic Salmonella replication within human macrophages" by 1st author Dr. @marisaegan.bsky.social (@cambupenn.bsky.social alum, now faculty @swarthmorecollege.bsky.social)! elifesciences.org/articles/90107 🧵(1/n)

Biologists have built one of the most detailed pictures ever of the changes that occur in women’s bodies before and after pregnancy, by pooling and studying around 44 million physiological measurements from more than 300,000 births https://go.nature.com/4236GSV

The loss of TBK1, or both TBK1 and the related kinase IKKε, results in uncontrolled cell death–driven inflammation. We show that TBK1/IKKε prevent premature cell death by limiting the activity of multiple death pathways in myeloid cells. www.science.org/doi/10.1126/...

Delighted to see our latest paper selected as “Research Highlight” by @natrevrheumatol.bsky.social ! Original study @naturecomms.bsky.social : rdcu.be/d7lK5 #lupus #innateimmunity #autoimmunity #ImmunoSky

Registration opens soon for the second Pattern Recognition receptor symposium in Lausanne Switzerland in October 2025. Check out the link for the great list of speakers. wp.unil.ch/immunobiolog...

Congrats to lab member Elliott for winning the poster prize at the Swiss LS2 conference for his work on the activation mechanism of Ninj1 during cell death!! 🥳 @dib-unil.bsky.social @lifesciswitzerland.bsky.social

The European Federation of Immunological Societies is leading a Women in Immunology 🔬🧪 campaign 🙌 From Feb 11- International Day of Women and Girls in Science, to Mar 8- International Women’s Day Follow along for their different activities - and thanks for selecting our #gender #equality article 😀

Happy International Day of Women and Girls in Science! Its been a privilege to work with these extraordinary scientists in my lab over the years - all making an incredible impact throughout the world 🙌 We must never give up on #equality #diversity & #inclusion 💪 #WomeninScience #GirlsInSTEM 🧪🔬🔭🚀

Check out our new pre-print from the @jourdainlab.bsky.social, featuring work led by @marcellharhai.bsky.social! How do growth and death screens compare when uncovering novel regulators of mitochondrial function? Is Ménière disease a mitochondrial disorder? Find out below 👇

New preprint from the lab! 🚨 🧫 New galactose #CRISPR screening strategy 🎯 481 genes required for #OXPHOS ⚙️ #FAM136A in IMS proteostasis 👂Mito defects in #Menieres disease by @marcellharhai.bsky.social @fbm-unil.bsky.social A short thread 1/5 www.biorxiv.org/content/10.1...

First PhD manuscript preprint OUT NOW! ‼️ 🧫 New galactose #CRISPR screening strategy 📝 Updated OXPHOS-regulating gene inventory 🧬 #FAM136A in the IMS 👂 Mito defects in #Ménière’s disease All come together in our latest work available at www.biorxiv.org/content/10.1...

The excellent Swiss Virology Meeting just ended. Thanks to the organizers and participants for making it such a warm and collegial environment. Here Magalie and I are with the project that began as her masters project. 🦠🚀

Our paper out @Nature: CARD domains mediate anti-phage defense in bacterial gasdermin systems CARDs are essential for caspase recruitment during human inflammasome activation. We now find them in bacterial immune systems Congrats Tana Wein! Thank you Kranzusch lab! www.nature.com/articles/s41...

Much looking forward being part of this with: A. Ablasser L. Andreeva @audeber.bsky.social @jelenalab.bsky.social V. Dixit @v-hornung.bsky.social B. Lemaitre O. Majer @manellab.bsky.social E. Miao @oliveiramann.bsky.social M. Pasparakis @inflammasomelab.bsky.social @sparrerlab.bsky.social R. Vance

We are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info: wp.unil.ch/immunobiolog... #ImmunoSky

My first post on bluesky couldn't be happier: The first preprint of my PhD is out 🥳 We show that the inflammasome receptor NLRP6 is activated by sterile or pathogen induced endolysosomal damage. Thanks to @elliottbernard.bsky.social and @brozlab.bsky.social, including Louise, Gaël and Vanessa