Wow, that ain't great. #ResearchIntegrity concerns in ThermoFisher's validations of its own antibodies... Fraud by specific labs? That affects the lab, and to variable extents from "meh" to "eurgh", the field the lab published in. Fraud by companies selling reagents? #SciPub #FoSci

Lots of cognitive dissonance from reading Nature today

Identify. Attack. Resolve. The immune system follows a perfect defense program: ignore weak/self signals, attack true threats with force, then shut down to avoid damage. (1/2) www.science.org/doi/10.1126/...

Really important and relevant study in TB from @danbarberphd.bsky.social and colleagues. We need to re-think many assumptions. Nitric oxide production in mice has been a confounding factor. #tuberculosis

Don't be shy to take on a little two-week side project. These five months will be the most precious three years of your academic journey.

"Although animals in natural environments accumulate a wide range of experiences that allow them to calibrate threat assessment, most behavioral studies of anxiety rely on laboratory animals housed in static, impoverished conditions." 🔥 www.cell.com/current-biol...

ICYMI: a quick calculation of transmembrane domain-containing proteins in a proteome. If you need to use this info: the code is in the post, or you can cite it since all quantixed posts have their own DOI courtesy of Rogue Scholar. doi.org/10.59350/0ah...

I'm looking for #NewPIs (<3 years as lab heads) in the gene regulation/functional genomics space. If you are one or know one, please comment below! 🧪

www.nature.com/articles/d41...? A researcher at Gothenburg U made up a skin problem caused by too much screentime, and uploaded a popular science piece and "preprints" online. Soon, LLMs would treat the condition as real, and the fake study cited in real medical papers.

The beauty and value of studying non-model organisms:

Open postdoc position in my lab on HGT and interbacterial competition. We seek candidates with a PhD in microbiology (or related fields)+ strong 1st-author publications. Curious, highly motivated, and dedicated team players ready to contribute fully are encouraged to apply. Details: tiny.cc/cz01101

If we want to understand and treat human diseases, we need to have better and human-specific models. Many excellent talks and posters today at #BonnOrganiodSymposium2026 highlight new directions in #organoid, ex vivo tissue models and #organ-on-chip development and application:

Want to know how cancer vaccines can keep you alive? Very pleased to join several luminaries in the field to offer a comprehensive review on this important topic. @harvardmed.bsky.social @bostonchildrens.bsky.social #cancer #vaccine www.nature.com/articles/s41...

We’re happy to share our updated manuscript on Ninj1, incorporating measurements of membrane tension, cellular assays of ninj1 and ninj2 dimer stability and MD simulations of ninj1 oligmers opening and forming (see below!). @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

Sunday read: An excellent review from my friend and virology expert Jen Wuerth and @fischmidtlab.bsky.social on everything you want to know about inflammasomes in antiviral immunity, and how to find them: www.mdpi.com/1999-4915/18...

I can only recommend...

When someone says „Scientists do not want you to know“ you can dismiss everything from there on. Scientists want you to know. They are desperate that you know. They can’t shut up about what they found out and want you to know.

Our story on #FBXW7 and #biotin in #glutamine_addiction is now peer-reviewed and published in Molecular Cell! Heroic work led by the very first postdoc of the lab @miriamlisci.bsky.social. Have a look! www.cell.com/molecular-ce...

You are interested in immunology and how nucleic acid structures contribute to their function and how this impacts disease development - Rayk Behrendt and myself have open PhD positions for a joint PhD program between Bonn and Osaka.

We're thrilled to share the lab's latest publication demonstrating how caspase-4 and the non canonical inflammasome recognize cytosolic LPS by preferentially binding to the convex portions of membranes - both bacterial and micelles @cp-immunity.bsky.social www.sciencedirect.com/science/arti...

Scientist's way of saying 'I ❤️ you' "I found this paper/preprint that made me think of your project." "I checked the mice/cells/plates already." "I just sent you the edits you requested." "I have a slide/diagram that will work for that." "I had that problem with [lab equipment], I have a fix."

Preprint: fever is beneficial for antimicrobial defence by raising AMP activity towards bacteria while reducing mitochondrial damage when pathogens are absent www.researchsquare.com/article/rs-8... @ucirvine.bsky.social

Too much data, too little thinking. A important essay from Ruslan Medzhitov on the importance of understanding data, not just generating it. A must read. @Yale www.nature.com/articles/s41...

2nd postdoc job alert in the Crick Institute in London. Project will examine the role of motors & the cytoskeleton (actin, septins and microtubules) during vaccinia virus egress using biochemical, structural & cellular approaches + live cell imaging. spread the word. crick.ac.uk/WayPostdoc20...

Does anyone have any experience with the Navinci Diagnostics Naveni PLA kits, especially in comparison with Duolink PLA reagents? I would extremely appreciate any information and feedback regarding the sensitivity and specificity

Recruitment for the EMBL International PhD Programme is officially open! 🔊 At EMBL, we train young scientists to become skilled and creative future leaders in academia, industry and other sectors. Start your career in the life sciences with us! 🔎 Read more here: tinyurl.com/4jdt2ra5

Methods should be used as widely as possible, so here is our detailed lipid imaging protocol, written with @martinba99.bsky.social and Chia-Yi (Christine) Chou authors.elsevier.com/a/1mU4XHRzCb... in Methods in Enzymology. Everything you need to know to do it yourself is in there -

I’m stoked to share my postdoc work with @sunnyshinlab.bsky.social, a collaborative effort with @metabailism.bsky.social & Brian Goldspiel, aided by many valued collaborators: Environmental Amino Acid Sensing Regulates the Rate of ASC Translation and NLRP3 Inflammasome Assembly. Some big takeaways:

Ever wondered how you can specifically inhibit #AIM2 #inflammasomes? @y-m-tesfamariam.bsky.social generated inhibitory AIM2 #nanobodies to ‬dissect inflammasome responses to #poxvirus infections in human #PrimaryCells @unibonn.bsky.social @immunosens.bsky.social link.springer.com/article/10.1...

If you are looking to build your lab, take a listen to these interviews on @lonelypipette.bsky.social! www.buzzsprout.com/1356877/epis...

Hi Bluesky! I’m a molecular virologist studying how innate immune defences restrict cross-species transmission and shape disease severity. I just joined, so reposts appreciated to help me reconnect with virology, immunology, and host–pathogen interaction folks. (whiteboard art from Zhuonan Li)

We know that diet and lifestyle are strong modulators of inflammatory response, but the exact mechanisms are still elusive. Now the study below adds a piece to this puzzle:

10 days left to apply! 👇

Does anybody here have a hands-on experience with SinoBiological antibodies, particularly in immunofluorescence/immunohistochemistry and/or WES/JESS?

We have an interesting observation (one data figure with several experiments) regarding one of the commonly used tools, which we believe might be important for the #CellDeath community. Which of cell death/immunology journals still publish article types such as "Correspondence", "Brief reports" etc?

As 2025 is drawing to a close, @jem.org would like to highlight all of the women who have contributed to the #WomenInSTEM #Viewpoint series over the last 3 years! Learn more about their scientific journeys on the path to independence here 👉 tinyurl.com/2wrxk4mk

A weekly issue of Biomed news on everything related to #CellDeath, with some additional papers on other aspects of innate immunity and host-pathogen interactions: biomed.news/bims-cediti/...

The one validated intervention to slow aging and extend healthspan is not for sale. It's exercise. sciencedirect.com/science/arti...

🤝 To promote representation and diversity, yEFIS is creating a 🌟 Rising Star 🌟 list of researchers to support speaker selection. 📝 Please nominate rising stars in your network via this form: 🔗https://docs.google.com/forms/d/e/1FAIpQLSe73pDfFGYBi_hKVqNjkFA65tcb5_KRx3LGpirBzmNMR6dyug/viewform

🚨 Join our lab - we are recruiting a PhD student! Application deadline: 20.12.2025 Starting date: from 1.04.2026 More info and application👇 Please share @dib-unil.bsky.social @fbm-unil.bsky.social #immunosky

Want to analyze the role of endogenous retroviruses in early human development or investigate their regulation in pluripotency and early development for your PhD? Join the lab of @fueyoraquel.bsky.social via the IMPRS-BAC #gradschool! 👉 www.molgen.mpg.de/5094682/Fuey...

We are hiring! 🎓🧫 🧬 Fully funded Postdoc position available in #Immunology at the University of Cambridge. Exceptional opportunity to study human tissue resident T cells across space and time in one of the world's top academic institutions. #postdoc #ERC www.cam.ac.uk/jobs/researc...

Reminder to apply - talk applications accepted continuously, there is no deadline. We will be seeking speakers throughout all of next year, so if you have a story on metabolism in development you're excited to share, here's the perfect place:

A traditional weekly issue of BioMedNews on everything #CellDeath -related: biomed.news/bims-cediti/...

Your periodic reminder that science is not done by a few selected "stars scientists". Science is done by hundred of thousands. Siloed money mean a few flashy discoveries and a lot of waste. Want to change things? Make funding accessible and stop funding calls with less than 2% success rate.

ERC success rates are tanking and the move is... even bigger grants for fewer people? smh

Ferroptosis induced by inhibition of GPX4 suppressed tumor growth in 2D, but not in 3D or in vivo. Lipids are different "Lipid Composition Alters Ferroptosis Sensitivity" aacrjournals.org/cancerres/ar...

Staphylococcus aureus induces Gasdermin A-dependent keratinocyte pyroptosis www.nature.com/articles/s41... @natcomms.nature.com @emoryuniversity.bsky.social @larocklab.com

Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination | PNAS www.pnas.org/doi/10.1073/...

🧬 Have you taken the survey yet? EFIS, yEFIS & University of Exeter want to hear from anyone working in immunology. https://loom.ly/Ud8A7s4 @efis-immunology.bsky.social @yefis-immunology.bsky.social