Why do animals age in such similar ways, yet live for wildly different spans - from days to a century? Our new paper in @NatureAging fits a damage accumulation model across 9 species and finds the knob that best predicts lifespan doi.org/10.1038/s435...

What happens just before we die? Are the last stages of deterioration driven by different dynamics, or the same processes driving aging all our lives? Turns out it's the latter, as we show in our new preprint! 🔬 doi.org/10.64898/202... 🧵 1/5 #AgingResearch #SystemsBiology

Identify. Attack. Resolve. The immune system follows a perfect defense program: ignore weak/self signals, attack true threats with force, then shut down to avoid damage. (1/2) www.science.org/doi/10.1126/...

Recommended listening. I was hosted on the podcast “Gil Hameever” to discuss our latest paper about the sudden physiological changes at menopause. The conversation is in Hebrew. open.spotify.com/episode/0EVA...

We analyzed changes in physiology relative to menopause using two large scale studies that include millions of lab tests. Rather than align by age, we used statistical inference to align tests to final menstrual period. (1/2) arunamed.com/the-menopaus...

Why does innovative research necessitate a jump into the unknown? Find out (and much more) in episode 147 of רעב לידע עם אור דניאל (Hungry for Knowledge with Or Daniel)! www.learntech.co.il/podcast/pod1...

Sweet moment in life, our 25th lab anniversary. In a circle, we looked at each other, a group of people with shared values and a soft approach, who want each other to succeed and be happy. (1/2)

Masterpiece by a masterful scientist Natural Neuroscience by Nachum Ulanovsky @mitpress.bsky.social mitpress.mit.edu/978026204499...

Our latest on aging, where we reveal an unexpected link between healthspan and equality of lifespans. By @y1fanyang.bsky.social , out now @naturecomms.bsky.social www.nature.com/articles/s41...

Now in French and Spanish - our pregnancy paper is highlighted also in @lefigaro.fr and @elpais.com sante.lefigaro.fr/medecine/com... elpais.com/salud-y-bien...

Amazing clinical epidemiology! The power of numbers! @urialonlab.bsky.social www.nature.com/articles/d41...

We now have our most detailed picture yet of how pregnancy affects the body on a weekly basis from 20 weeks pre-conception to 1.5 years after delivery. Fab work from @urialonlab.bsky.social Read @newscientist.com. www.newscientist.com/article/2473...

"Pregnancy’s true toll on the body: huge birth study paints most detailed picture yet" Our study highlighted in @nature.com News www.nature.com/articles/d41...

Excited to share our new study revealing the intricate dynamics of pregnancy & postpartum physiology! We analyzed 40M lab tests from 300K pregnancies and 160K women (cross-sectional) and mapped week-by-week changes starting from preconception to months-long postpartum recovery.

Harnessing huge data from pregnancy natural experiments @urialonlab.bsky.social www.science.org/doi/10.1126/... www.science.org/doi/10.1126/...

Theory predicted two kinds of fibrosis, hot and cold. We show in vivo that hot and cold fibrosis describe heart failure, and heart attack, respectively, showing that they are very different disease states. @shovalmiyara.bsky.social @eldadtzahor.bsky.social

Sagol lecture in longevity research - Myriam Grunewald on vasculature maintenance for longevity

Join us at the ICSB in Dublin this October - I will chair the session on aging systems biology icsb2025.com

It’s finally here! My PhD work, five years in the making, is now published @CellSystems @cellpress.bsky.social 🚨 Cold and hot fibrosis define clinically distinct cardiac pathologies. www.cell.com/cell-systems...

My brilliant PhD student @Yaelebel.bsky.social gave a talk at the Azrieli Graduate Students forum about her research on using excitable dynamics to explain pulsatile immune phenomena, and how research questions can come from the most unexpected places. Well done Yael! youtu.be/MdwqWx5emo4

Will be attending the Quantitative Immunology workshop at the Princeton Center for Theoretical Science later month. pcts.princeton.edu/events/2025/...

Why do cortisol-lowering drugs work for Cushing’s but fail in mood disorders & chronic stress? We propose that the ability of the pituitary and adrenal glands to adjust their functional masses—normally beneficial—counteracts the drug’s effect. Using a math. model, we screened HPA interventions (1/2)

@urialonlab.bsky.social lab reveals a hormone circuit that explains why most HPA drugs fail for mood disorders and predicts the few that work ➡️ www.embopress.org/doi/full/10....

Really enjoying Uri Alon’s characteristically wonderful lectures on aging: www.weizmann.ac.il/mcb/alon/cou...

Videos and lecture notes from my latest course, Systems Aging, are available now at: www.weizmann.ac.il/mcb/alon/cou...

Excited to speak at the Global Conference on Gerophysics, where we'll explore how physics can revolutionize our understanding of aging and mortality. Join us and get 10% off registration with code GCGP10. See you there, and sign up here: medicine.nus.edu.sg/trp/healthy-...