Interesting, and sequencing-based. "These findings definitively point to the ancestral origin of the Columbus lineage within the noble houses of Northern Spain, specifically the Zúñiga (Navarre) and Sotomayor (Galicia) families" Do you reckon this will settle things? www.biorxiv.org/content/10.6...

The United States now has the most government restrictions on academic freedom of any high-income country. www.chemistryworld.com/news/academi... Raw data from @vdeminstitute.bsky.social —> academic-freedom-index.net/research/Aca...

"Tell me who your friends are, and I’ll tell you who you are." It turns out, microbes follow the same rule! Very proud to share our lab's new paper in @natmicrobiol.nature.com showing that bacteria don't just respond to their environment, they respond to each other. www.nature.com/articles/s41...

Check out Snorre's latest preprint: www.biorxiv.org/content/10.6... I love this story: our 4-species synthetic bacterial community coexists across many simple environments and conditions. We show why (spoiler in the title)

En #AGolpeDeBit #RTVE, @sanmillan.bsky.social investigador del #CNB @csic.es habla de este estudio liderado junto a Alfonso Santos López @uam.es y en colaboración con Ayari Fuentes #UNAM_MX centrado en el plásmido pOXA-48 de gran interés clínico 📻 ¡No te lo pierdas! www.rtve.es/play/audios/...

New preprint alert!!! 🚀🤓 We are very happy to finally share this with the world — the result of seven years of work and a new tool to study integrons and discover new functions encoded in these bacterial platforms. If you want to know more, here is a thread 🧵 www.biorxiv.org/content/10.6...

Bacteria have been fighting off viruses using a huge arsenal of molecular weaponry that scientists did not know about — until now. Researchers have identified proteins that could lead to virus-fighting drugs and technologies. go.nature.com/4dqQnXI

How diverse is bacterial immunity ? We report in @science.org how language models allowed us to predict 2.4M antiphage proteins spanning >23K novel potential systems. 👏 @emordret.bsky.social, @alexhv.bsky.social & al doi.org/10.1126/scie... Explore them here defensefinder.mdmlab.fr/wiki/refseq_...

A big advance in the field of bacterial immunity, from the Bernheim and Laub labs

Cool tool to capture genes using a hunter gatherer 🦠 Large-scale recovery of integron cassettes for gene discovery screens www.biorxiv.org/content/10.6... by @jaescudero.bsky.social @afpcarvalho.bsky.social @filipatr.bsky.social

1. Despite limited Ab exposure, the Wayampi gut microbiome harbors a robust "background" resistome of ACQUIRED resistance genes (antibiotic, metal, biocide) shared with Westerns=AMR is an ancient and conserved feature rather than solely a by-product of human activities.

1/11 First, I want to thank the mastermind behind this project @jaescudero.bsky.social , who dreamed and battled alongside me to get here. And it wasn't a walk in the park 😅

New blog post: The Camel's Camel. Today, I found a beautiful example of synonymized plagiarism involving the microbiome of a camel’s udder. #TorturedPhrases #ScienceIntegrity #ResearchIntegrity scienceintegritydigest.com/2026/03/12/t...

I am not very active lately in social media, but if you want to see one of our latest works check Alberto’s post on the fitness cost of AMR genes. Great delivery from him and all collaborators. Thanks, guys! bsky.app/profile/albe...

Great work led by MBAlab @jaescudero.bsky.social with the invaluable collaboration of @sanmillan.bsky.social @baerboletta.bsky.social @penamiller.bsky.social and @ayari.bsky.social

Excited to share our latest work! 📝 We measured the fitness effect of 136 AMR genes and found that many are neutral or even beneficial without selection. 🤯🧬 Oxygen availability can flip their fitness and our stochastic model indicates that oxygen fluctuations help maintain them. Learn more 👇🏼

👏 Dos proyectos del #CNB seleccionados en la convocatoria de Investigación en Salud 2025 de la @caixaresearch.bsky.social Ambos abordan un gran reto global: la resistencia a los antimicrobianos. #HealthResearch #FundaciónlaCaixa @sanmillan.bsky.social @jaescudero.bsky.social f.mtr.cool/jejatlbssz

New preprint out! 📣🚨 We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠 #Microsky

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

Excited to share my latest review, now published in the Royal Society theme issue on ‘The ecology and evolution of bacterial immune systems' (available OA): Defence systems encoded by core genomic islands of seventh pandemic Vibrio cholerae royalsocietypublishing.org/doi/10.1098/...

El próximo 5 de septiembre en nuestro #47congresosebbm tendrá lugar la entrega del Premio Fundación Lilly a la Mejor Tesis Doctoral en Bioquímica y Biología Molecular a Alberto Hipólito Carrillo por el trabajo de su tesis. https://f.mtr.cool/rnstpoiucs

El próximo 5 de septiembre en nuestro #47congresosebbm tendrá lugar la entrega del Premio Fundación Lilly a la Mejor Tesis Doctoral en Bioquímica y Biología Molecular a Alberto Hipólito Carrillo por el trabajo de su tesis. https://f.mtr.cool/czgfpzevqu

Are Bacterial Processes Dependent on Global Ribosome Pausing Affected by tRNA Modification Defects? 🦠 =>processes evolutionarily tuned to be sensitive to translation speed eg: motility, iron homeostasis, leader peptide attenuation (ex: trp). #rnasky #microsky www.sciencedirect.com/science/arti...

Oxygen levels can affect how resistance genes work, impacting antibiotic efficacy. This can be relevant for the most used ones: for example, resistance to fosfomycin varies with oxygen. Learn more in our latest paper 👉 bit.ly/3T8sdpp a work led by @jaescudero.bsky.social #AntibioticResistance

A 2 yr postdoc position at the Bacterial Genome Plasticity Unit of the Institut Pasteur (Paris) led by @amazeld.bsky.social in collaboration with Pierre-Alexandre Kaminski, funded by the French National Research Agency 👇

🚨🚨 New paper in @narjournal.bsky.social! 🍾 Excludons are pairs of overlapping genes that block each other’s expression (basically, reverse operons). We built a tool to identify them in bacterial genomes using transcriptomic data, in an awesome collab led by Iñigo Lasa and Álvaro San Martín. 👇

When the MSc student of Enea @phagemuffin.bsky.social is working in a brewery... 🍺🧬

A gym that you go to but instead of working out you write papers

Do plasmids evolve faster 🐇, slower 🐢, or just like chromosomes 🧬? In our new paper, we tackled this question using theory, simulations, bioinformatics, and experiments! 👇 Check out all the details in Paula’s thread! Hint: 🐇 (most of the time)

I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!

We are on the lookout for postdocs for two different projects at the intersection of ecology, evolution, and the human microbiome. See thread for more information and reach out!

A #short about mirror bacteria in French with subtitles, except for me, by @leblob.bsky.social youtube.com/shorts/i0N55...

This Craig Maclean guy looks like he’s going places, one to keep an eye on! 👀

New paper with @rwheatley8.bsky.social and Cedric Lood Actual title: Chromosomal capture of beneficial genes drives plasmids towards ecological redundancy. Sensationalist title: Plasmids carry useless genes academic.oup.com/ismej/articl...

Super proud of the lab for their outstanding presentations at #FEMS2025 in Milano! Science is better when you work with such a stellar team!🚀✨ @femsmicro.org

Proud of the talk of Iván Linares at the #FEMS2025 on hospital-associated microbiomes and its role on pathogens persistance 🦠 @femsmicro.org

Great session! A pity it was only 2'5h and not the full day 😅. Computing with oscillations encoding information in frequency, distributed computing with high information capacity wires, neuromorphic computing at the verge of learning, stochastic and probabilistic computing, heterotic computing...

Thrilled to announce I've been awarded a @wellcometrust.bsky.social Career Development Award at @fbmh-uom.bsky.social , University of Manchester! My research will investigate the remarkable adaptability of Aspergillus fumigatus, a deadly fungal pathogen, to help combat drug resistance.

Super proud of amazing lab alumnus @mbottery.bsky.social who has been awarded a prestigious @wellcometrust.bsky.social fellowship to grow his lab @officialuom.bsky.social studying the evolution of fungal pathogens! Mike has multiple postdoc positions available on his exciting project (details 👇)

My summer read. Well, actually not sure it will make it to August untouched…

Webinar on Mirror Biology: Global risks, national security concerns, and practical actions Jul 17, 2025 12:00 PM ET Hosted by Brown Pandemic Center Register here: brown.zoom.us/webinar/regi...

Great afternoon with friends at @seqcoast.bsky.social esp @microbigal.bsky.social Our business is growing and sequencing and analysis services are better and more diverse than ever. Delighted they sponsored the best GRC, full stop!

Super stoked and honored to be elected as co-chair along with @ksbakes.bsky.social for the Microbial Population Biology 2029 GRC! And looking forward to a great 2027 meeting in Andover chaired by @drhhnz.bsky.social and @wcratcliff.bsky.social !

Going back home after my first GRC conference… what a week! It was a blast!

Bluesky is now giving notifications for likes on reposts to the reposter. Excited that this may help folks recognize how high engagement is here. Just a reminder that reposts are critical here without the algorithm. Late reposts are especially helpful for those who log in infrequently.

Thrilled (and humbled!) to share that since today I am the Chair of the Virology Department at @pasteur.fr. Grateful to my colleagues for their trust. Now let’s push the frontiers of virus research together. The sky is the limit! 🦠🔬 #Virology #Science #TeamPasteur

Our paper demonstrating that within-species warfare interactions are ecologically important on human skin is now published in Nature Micro! www.nature.com/articles/s41...

‼️I'm looking for a postdoc‼️ Come join effort in using metagenomes to quantify microbial catabolic potential and carbon substrate availability at the ecosystem level. We seek to understand evolutionary forces shaping the carbon cycle. Part of ccomp-stc.org careers.peopleclick.com/careerscp/cl...

Highly recommended read: I am guilty of a couple of young PI mistakes, indeed. I also fiercely support the “publish less, publish better” motto. Enjoy! doi.org/10.1111/1751...