New preprint out! 📣🚨 We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠 #Microsky

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

Excited to share my latest review, now published in the Royal Society theme issue on ‘The ecology and evolution of bacterial immune systems' (available OA): Defence systems encoded by core genomic islands of seventh pandemic Vibrio cholerae royalsocietypublishing.org/doi/10.1098/...

El próximo 5 de septiembre en nuestro #47congresosebbm tendrá lugar la entrega del Premio Fundación Lilly a la Mejor Tesis Doctoral en Bioquímica y Biología Molecular a Alberto Hipólito Carrillo por el trabajo de su tesis. https://f.mtr.cool/rnstpoiucs

El próximo 5 de septiembre en nuestro #47congresosebbm tendrá lugar la entrega del Premio Fundación Lilly a la Mejor Tesis Doctoral en Bioquímica y Biología Molecular a Alberto Hipólito Carrillo por el trabajo de su tesis. https://f.mtr.cool/czgfpzevqu

Are Bacterial Processes Dependent on Global Ribosome Pausing Affected by tRNA Modification Defects? 🦠 =>processes evolutionarily tuned to be sensitive to translation speed eg: motility, iron homeostasis, leader peptide attenuation (ex: trp). #rnasky #microsky www.sciencedirect.com/science/arti...

Oxygen levels can affect how resistance genes work, impacting antibiotic efficacy. This can be relevant for the most used ones: for example, resistance to fosfomycin varies with oxygen. Learn more in our latest paper 👉 bit.ly/3T8sdpp a work led by @jaescudero.bsky.social #AntibioticResistance

A 2 yr postdoc position at the Bacterial Genome Plasticity Unit of the Institut Pasteur (Paris) led by @amazeld.bsky.social in collaboration with Pierre-Alexandre Kaminski, funded by the French National Research Agency 👇

🚨🚨 New paper in @narjournal.bsky.social! 🍾 Excludons are pairs of overlapping genes that block each other’s expression (basically, reverse operons). We built a tool to identify them in bacterial genomes using transcriptomic data, in an awesome collab led by Iñigo Lasa and Álvaro San Martín. 👇

When the MSc student of Enea @phagemuffin.bsky.social is working in a brewery... 🍺🧬

A gym that you go to but instead of working out you write papers

Do plasmids evolve faster 🐇, slower 🐢, or just like chromosomes 🧬? In our new paper, we tackled this question using theory, simulations, bioinformatics, and experiments! 👇 Check out all the details in Paula’s thread! Hint: 🐇 (most of the time)

I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (garud.eeb.ucla.edu). If interested, please message me!

We are on the lookout for postdocs for two different projects at the intersection of ecology, evolution, and the human microbiome. See thread for more information and reach out!

A #short about mirror bacteria in French with subtitles, except for me, by @leblob.bsky.social youtube.com/shorts/i0N55...

This Craig Maclean guy looks like he’s going places, one to keep an eye on! 👀

New paper with @rwheatley8.bsky.social and Cedric Lood Actual title: Chromosomal capture of beneficial genes drives plasmids towards ecological redundancy. Sensationalist title: Plasmids carry useless genes academic.oup.com/ismej/articl...

Super proud of the lab for their outstanding presentations at #FEMS2025 in Milano! Science is better when you work with such a stellar team!🚀✨ @femsmicro.org

Proud of the talk of Iván Linares at the #FEMS2025 on hospital-associated microbiomes and its role on pathogens persistance 🦠 @femsmicro.org

Great session! A pity it was only 2'5h and not the full day 😅. Computing with oscillations encoding information in frequency, distributed computing with high information capacity wires, neuromorphic computing at the verge of learning, stochastic and probabilistic computing, heterotic computing...

Thrilled to announce I've been awarded a @wellcometrust.bsky.social Career Development Award at @fbmh-uom.bsky.social , University of Manchester! My research will investigate the remarkable adaptability of Aspergillus fumigatus, a deadly fungal pathogen, to help combat drug resistance.

Super proud of amazing lab alumnus @mbottery.bsky.social who has been awarded a prestigious @wellcometrust.bsky.social fellowship to grow his lab @officialuom.bsky.social studying the evolution of fungal pathogens! Mike has multiple postdoc positions available on his exciting project (details 👇)

My summer read. Well, actually not sure it will make it to August untouched…

Webinar on Mirror Biology: Global risks, national security concerns, and practical actions Jul 17, 2025 12:00 PM ET Hosted by Brown Pandemic Center Register here: brown.zoom.us/webinar/regi...

Great afternoon with friends at @seqcoast.bsky.social esp @microbigal.bsky.social Our business is growing and sequencing and analysis services are better and more diverse than ever. Delighted they sponsored the best GRC, full stop!

Super stoked and honored to be elected as co-chair along with @ksbakes.bsky.social for the Microbial Population Biology 2029 GRC! And looking forward to a great 2027 meeting in Andover chaired by @drhhnz.bsky.social and @wcratcliff.bsky.social !

Going back home after my first GRC conference… what a week! It was a blast!

Bluesky is now giving notifications for likes on reposts to the reposter. Excited that this may help folks recognize how high engagement is here. Just a reminder that reposts are critical here without the algorithm. Late reposts are especially helpful for those who log in infrequently.

Thrilled (and humbled!) to share that since today I am the Chair of the Virology Department at @pasteur.fr. Grateful to my colleagues for their trust. Now let’s push the frontiers of virus research together. The sky is the limit! 🦠🔬 #Virology #Science #TeamPasteur

Our paper demonstrating that within-species warfare interactions are ecologically important on human skin is now published in Nature Micro! www.nature.com/articles/s41...

‼️I'm looking for a postdoc‼️ Come join effort in using metagenomes to quantify microbial catabolic potential and carbon substrate availability at the ecosystem level. We seek to understand evolutionary forces shaping the carbon cycle. Part of ccomp-stc.org careers.peopleclick.com/careerscp/cl...

Highly recommended read: I am guilty of a couple of young PI mistakes, indeed. I also fiercely support the “publish less, publish better” motto. Enjoy! doi.org/10.1111/1751...

Nearly half of bacteria carry mobile, accessory PDF enzymes that can resist actinonin, new study reveals. Resistance to PDF-targeting antibiotics is already encoded and poised to spread. #AMR #MicroSky ✍️ @morgan-lamberioux.bsky.social and coll. @pasteur.fr 📖 shorturl.at/WTBVx

🥇Congratulations to David Bikard @dbikard.bsky.social on winning the EMBO Gold Medal! Well-deserved recognition for advancing synthetic biology and microbial genetics. 🔬✨ @embo.org www.embo.org/press-releas...

🚨Ampliamos al día 8 el plazo de envío de las comunicaciones y becas de viaje. Participa en las Reuniones de Grupos Científicos de la SEBBM. Presenta tu resumen científico y opta a los premios que tenemos para este #47congresosebbm 👏 https://f.mtr.cool/beyohtxqxj

🎉 Congratulations to David Bikard @pasteur.fr on his 2025 @embo.org Gold Medal win! 🧬 He's pioneering phage-CRISPR tools to edit gut #bacteria in vivo, reshaping the #microbiome from within and opening the door to targeted therapies. 👉 europa.eu/!HQbHTw 👉 europa.eu/!KtWf33 @dbikard.bsky.social

Love today’s #xkcd comic on #MassSpec 🤣

@ghafrance.bsky.social 80 chercheurs s'engagent pour faire de la recherche contre la tuberculose une priorité européenne ! www.actionsantemondiale.fr/app/uploads/...

"Science is a method for testing claims about the natural world, not an immutable compendium of absolute truths. The fundamentalists, by ‘knowing’ the answers before they start...lie outside the domain of science–or of any honest intellectual inquiry." - Stephen Jay Gould (1991) 🧪

Knock knock knock -Sarah Connor…

Exciting news!! Our latest paper is out in Nat. Microbiol. @natmicrobiol.nature.com We show that a sub-lineage of 7th pandemic V. cholerae has acquired mobile genetic elements packed with phage defense systems—rendering it multi-phage resistant 😳 ..... 1/3 www.nature.com/articles/s41...

I will be recruiting new postdocs with start dates end 2025 - early 2026. If you'd like to work at the Pasteur Institute in the heart of Paris surrounded by amazing scientists, reach out to discuss possible projects on SynBio / Bacterial Immunity!

Today, the ERC formally adopted a decision to increase its support for researchers moving to Europe. On top of its normal grants, the ERC offers 'start-up' funding to help PIs establish laboratories / research teams in Europe. This extra funding is now x2 (up to €2 million!) europa.eu/!6Vdgmp

Choose Science. Choose Europe. A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open. With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond. Apply by 10 September → europa.eu/!fBTMgF

1/6 Excited to share our review 🚀 🧬 CRISPR–Cas therapies targeting bacteria! #MicroSky

New opinion paper from the lab! www.cell.com/trends/micro...

🧫🦠🔬🧬 @science.org Mobile integrons encode phage defense systems | Science www.science.org/doi/10.1126/... @jaescudero.bsky.social @albertohca.bsky.social et al. #microbiology #phage #immunity #phagesky #MicroSky

Habemus paper! Our story on integron-encoded anti-phage defenses is now out in @science.org! 16 new systems, small versions of known ones, and a lot more in this highly-collaborative study. Many thanks to everyone involved, especially my supervisor @epcrocha.bsky.social bsky.app/profile/bapt...

Have also a look at our back-to-back study for mobile integrons by Nicolas Kieffer from @jaescudero.bsky.social group ! www.science.org/doi/10.1126/... + a similar story in V. parahaemolyticus by @landongetz.bsky.social from @themaxwelllab.bsky.social www.nature.com/articles/s41...