Mike Bottery
@mbottery.bsky.social
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Microbial Evolution - AMR - University of Manchester
reposted by
Mike Bottery
Fungal One Health and Antimicrobial Resistance (F1AMR) Network
6 days ago
"Fungal resistance is a silent and underestimated threat. The same substances helping to protect crops are also reducing the effectiveness of essential medicines. If we fail to act, we risk losing critical treatments and putting lives at risk”
@mbottery.bsky.social
www.fungalamr.org/post/three-u...
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Three urgent actions to tackle fungal antimicrobial resistance in the UK: a new paper
“Fungal resistance is a silent and underestimated threat. The same substances helping to protect crops are also reducing the effectiveness of essential medicines. If we fail to act, we risk losing cri...
https://www.fungalamr.org/post/three-urgent-actions-to-tackle-fungal-antimicrobial-resistance-in-the-uk-a-new-paper
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reposted by
Mike Bottery
MEEhubs
4 months ago
MEEHubs2026 registration and abstract submission is now online! 🚨🦠✨ Join us Aug 3 - 5, 2026 at one of the 7 hubs or online. We are incredibly excited about our lineup of speakers, and hope that you submit an abstract to contribute too! More information and registration links at:
meehubs.org
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Home
https://meehubs.org
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PhD Opportunity: Are you interested in evolutionary biology and the global challenge of antifungal resistance? We are seeking a motivated candidate for a President’s Doctoral Scholar Award 📅Deadline: March 16 2026 📍Location:
@manchester.ac.uk
@fbmh-uom.bsky.social
www.findaphd.com/phds/project...
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(PDS) Targeting Septal Plugging to Disrupt the Evolution of Antifungal Resistance in Hyphal Networks at The University of Manchester on FindAPhD.com
PhD Project - (PDS) Targeting Septal Plugging to Disrupt the Evolution of Antifungal Resistance in Hyphal Networks at The University of Manchester, listed on FindAPhD.com
https://www.findaphd.com/phds/project/pds-targeting-septal-plugging-to-disrupt-the-evolution-of-antifungal-resistance-in-hyphal-networks/?p194325
5 months ago
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Presenting my perspective on the role of academic science on the issues of antifungal dual use at the Brazilian Network Meeting on Aspergillus fumigatus Antimicrobial Resistance.
@f1amr-network.bsky.social
@fbmh-uom.bsky.social
7 months ago
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Exciting news! I have two positions open in my lab at the UoManchester: one PDRA and one Research Tech. Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!
8 months ago
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reposted by
Mike Bottery
Natalie Bennett
10 months ago
Currently hosting event on antifungals in medicine and agriculture, focusing on
#AntiMicrobialResistance
#AMR
. With 6.5 million invasive infections globally each year, and 3.8 million deaths attributable to them. Area of fast-rising concern!
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Very proud of Ed's first conference talk at
#BSMM2025
did great despite the technical hiccups!!
10 months ago
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reposted by
Mike Bottery
Bertuzzi Lab
about 1 year ago
Interested in working on Mucorales adaptation? Thanks to new funding from
@wellcometrust.bsky.social
, we will have two postdoc and a technician positions advertised very soon! if interested, please get in touch for more information.
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Thrilled to announce I've been awarded a
@wellcometrust.bsky.social
Career Development Award at
@fbmh-uom.bsky.social
, University of Manchester! My research will investigate the remarkable adaptability of Aspergillus fumigatus, a deadly fungal pathogen, to help combat drug resistance.
about 1 year ago
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reposted by
Mike Bottery
UK Health Security Agency
about 1 year ago
The MHRA today released new guidance for
#Phage
therapy in the UK. This will provide direction for scientists and researchers working to make this treatment a reality for patients. 🔬 🧪 🔗
www.gov.uk/government/n...
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reposted by
Mike Bottery
Michael Brockhurst
about 1 year ago
New preprint with nice detective work by PhD student Khadija Hanga: gain of pOXA MDR plasmid is facilitated by chromosomal mutations affecting OmpF which act synergistically with the plasmid’s carbapenamase to give high level resistance. Led by
@mbottery.bsky.social
www.biorxiv.org/content/10.1...
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Chromosomal resistance mutations facilitate acquisition of multidrug-resistance plasmids in Escherichia coli
Bacteria can gain multiple resistance mechanisms in a single step by the acquisition of multidrug-resistance (MDR) plasmids, but it is unclear how antibiotic selection during the acquisition of MDR pl...
https://www.biorxiv.org/content/10.1101/2025.04.15.648949v1
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@wellcometrust.bsky.social
Thanks for organizing the ERC meeting. I found the research culture activity really helpful, so many great thought-provoking ideas
over 1 year ago
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Beautiful day to get out of the office and do some fieldwork! Soil samples + 🍄
#failsafe
#mycology
@normanvanrhijn.bsky.social
over 1 year ago
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New in Nature Comms, we show that azole-resistant Aspergillus fumigatus are more likely to evolve resistance to new antifungals due to variants in their DNA mismatch repair system
rdcu.be/d3Iyc
@natureportfolio.bsky.social
#microsky
#fungi
#amr
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Elevated mutation rates in multi-azole resistant Aspergillus fumigatus drive rapid evolution of antifungal resistance
Nature Communications - Here, Bottery et al show that resistance to next generation antifungals is more likely to occur within azole resistant Aspergillus fumigatus due to the close linkage between...
https://rdcu.be/d3Iyc
over 1 year ago
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reposted by
Mike Bottery
Michael Brockhurst
over 1 year ago
In case you missed it:
@matthewjshepherd.bsky.social
surveyed the clinical literature to reveal how
#AMR
evolves within patients, why eco/evo mechanisms vary among infections, & what we can do better to improve treatments
www.nature.com/articles/s41...
#MicroSky
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Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance - Nature Reviews Microbiology
In this Review, Shepherd, Brockhurst and colleagues explore the clinical evidence in support of four major ecological and evolutionary mechanisms of within-patient antimicrobial resistance emergence i...
https://www.nature.com/articles/s41579-024-01041-1
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It was great fun to be part of this project! Super cool to see Rock-Paper-Scissors dynamics in real microbial populations
add a skeleton here at some point
over 1 year ago
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PhD studentship alert! Fully funded, co-supervised with
@rokkrasovec.bsky.social
and Prof Mike Bromley, University of Manchester Exploring routes of horizontal gene transfer in pathogenic fungi Exciting project, will be a bunch of fun! Come & join us 🔬
www.findaphd.com/phds/project...
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https://www.findaphd.com/phds/project/bicentenary-tracking-horizontal-gene-transfer-and-the-spread-of-antimicrobial-resistance-in-pathogenic-fungi/?p178981
over 1 year ago
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reposted by
Mike Bottery
Chris Knight
over 1 year ago
Soil microbiomes show consistent and predictable responses to extreme events We’re out in Nature !!
doi.org/ntzk
Very exciting for my first bluesky post! – it’s been a long haul by an excellent team from across Europe, led by
@frantecol.bsky.social
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Soil microbiomes show consistent and predictable responses to extreme events - Nature
Soils from 30 grasslands across Europe were subjected to 4 contrasting extreme climatic events under drought, flood, freezing and heat conditions, with the results suggesting that soil microbiomes fro...
https://doi.org/ntzk
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Fungal Genetics Stock Centre, there's something fishy going on here...
over 1 year ago
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It was a pleasure to have the opportunity to present our work!
add a skeleton here at some point
over 1 year ago
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Excited to be giving a talk this afternoon on the risk of AMR evolution in fungal pathogens
@newcastleuni.bsky.social
#WAAW
#AMR
over 1 year ago
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