Bacteria chromosomes contain Genomic Islands that provide virulence, antibiotic resistance, MGE-defence,... They transfer between cells, but the mechanism of most remains elusive. Here we explore the conjugative capacity of these mysterious Genomic Islands. www.biorxiv.org/content/10.6...

A federal judge on Wednesday ordered federal agents to stop detaining and deporting refugees in Minnesota who were lawfully admitted to the U.S., granting a temporary restraining order, which halts for now the Trump administration’s operation. The administration is likely to appeal the ruling.

Wikipedia is needed now more than ever, 25 years on www.nature.com/articles/d41...

And what a beautiful @pnas.org cover @paularamiro.bsky.social and @jerorb.bsky.social !!!!!! You should be very proud!

Congratulations to @paularamiro.bsky.social and the @jerorb.bsky.social ´s group and collaborators! A must reading for understanding plasmid biology, bacterial evolution and evolution more broadly. Bravo! 👏👏👏 👇

I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good. Stay free

❗ Investigadores españoles logran eliminar por completo tumores de páncreas en ratones utilizando una triple terapia. Este hito alcanzado por primera vez abre la puerta a tratamientos en humanos para uno de los cánceres más mortales

1/¿Podemos detectar la meningitis con ultrasonidos e IA? En este nuevo News From The Lab, la investigadora Sara Ajanovic (ISGLOBAL - Hospital Vall d’Hebron) nos presenta Neosonics, una innovadora herramienta que diagnostica de forma rápida y no invasiva. bit.ly/49dNGGb

'La angustia de no tener un hogar', la carta al director de Mireia Carrillo. Puedes leer más cartas al director aquí 👉 social.elpais.com/j9vci10

19/ 🔚We have reached the end of the event! Thank you for joining us and for your commitment to the future of health. Congratulations to all the selected projects!🎉👏 Stay tuned, we’ll be sharing more highlights and details from the ceremony soon!👀

1/ Antibiotic resistance causes ➕ than 1 M deaths each year and understanding why this happens is key to stopping it. With #HealthResearch support, @sanmillan.bsky.social#HealthResearchis investigating how different plasmids (DNA fragments) coexist in bacteria and confer resistance. https://tinyurl.com/3bysv6cr

2/ 🤝 This project is carried out at @cnb-csic.bsky.social is conducted in consortium with @tmcoque.bsky.social (Instituto Ramón y Cajal de Investigación Sanitaria).

A pleasure and an honour to have received this prestigious grant with my admired colleagues and friends @sanmillan.bsky.social and @asanchezlab.bsky.social . More about AMR under plasmid lens!. My sincere gratitude to @caixaresearch.bsky.social @microryc.bsky.social @esgem-sg.bsky.social

❗ Descubren una nueva combinación de fármacos que reduce un 40% la mortalidad en cáncer de próstata recurrente

Asientos de avión cada vez más pequeños, prendas irreconocibles al segundo lavado, máquinas que te atienden por teléfono para cualquier trámite. El cuidado por las cosas bien hechas parece haber dejado de ser un valor que cuenta

Ecological and evolutionary consequences of changing seasonality | Science @jdtonkin.bsky.social www.science.org/doi/10.1126/...

Its here! Finally published. www.tes.com/magazine/tea...

Cool work by Sanasar investigating how bacteria-phage dynamics affect the distribution of antiphage defense systems in the genome www.biorxiv.org/content/10.1...

Our latest preprint just dropped @paulturnerlab.bsky.social We evolved bacteria on swim plates, against a phage that attacks through the flagellum. Motility trades off AND trades up(!!) with phage-resistance! www.biorxiv.org/content/10.1...

New paper from my lab (first author is Sonia Ghose): www.frontiersin.org/journals/mic... Skin microbiomes of frogs vary among body regions, revealing differences that reflect known patterns of chytrid infection

And this is also what we see experimentally! Defensive or co-invading CRISPR-Cas are always beneficial, but offensive CRISPR is severely limited by and even detrimental when there is TA. 4/6

Our opinion piece on transmission timing in phages and plasmids graces the cover of @cp-trendsmicrobiol.bsky.social this month. Featuring the work of talented master student Andrina Bernhard, the illustration showcases cues that MGEs use to switch between horizontal and vertical transmission.

Good papers, like good wine, need maturing. I'm proud and thrilled to share our work on genomic epidemiology of K.pneumoniae in Valencia and differential transmission patterns of resistances, part of Neris Garcia's PhD thesis and the NLSAR consortium. go.uv.es/td8iL4c #publichealth #EpiSky 🧬🖥️

New preprint alert 🚨: We found that Steno maltophila senses a quorum sensing molecule from the co-infecting pathogen Pseudomonas aeruginosa and switches to multicellular aggregates as a protective mechanism. #MicroSky www.biorxiv.org/content/10.1...

Calling all evolutionary biologists! 👇👇👇

Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".

Biofilm architecture determines the dissemination of conjugative plasmids: We measured the spatiotemporal spread of plasmids in biofilms and found that plasmids only spread in some biofilm regions! Collab with lab of @sbigot.bsky.social & Christian Lesterlin www.pnas.org/doi/10.1073/...

Several research institutes in Germany are joining a worldwide grassroots effort to save science data sets that researchers fear could be deleted by US President Donald Trump’s administration, Nature has learnt. https://go.nature.com/42uEw50

ESGEM, the ESCMID Study Group on Epidemiological Markers is launching a working group to develop standards for interpreting AMR genotypes. Much like EUCAST guidance for interpreting lab phenotypes as S/I/R, we want to define the AMRrules for interpreting genotypes.

La estadounidense Brooke Raboutou se convierte en la primera mujer en alcanzar el 9b+, una dificultad que solo habían superado ocho escaladores masculinos. Hija de dos leyendas de la escalada, Raboutou, de 24 años, encadenó la vía ‘Excalibur’

New paper: long-term trends in antibiotic resistance show signs of stabilisation (thread). journals.plos.org/plospathogen...

TWO postdoc positions in Computational Microbiology and/or biochemistry. Join our interdisciplinary group in the new Life and Mind Building @OxfordBiology, @UniofOxford, @IneosOxford Please apply and share this post: www.jobs.ac.uk/job/DMP641/p...

If you are interested in phage satellites, we hope you'll enjoy this. Fun collaboration with the Rocha, Seed, Bikard, and Chen labs! rdcu.be/efkvG

The Trump Administration’s abrupt withdrawal of $400 million in federal funding from Columbia University cast a shadow over at least nine other campuses worried they could be next. www.nytimes.com/2025/03/08/u...

Cualquier excusa es buena (la mención de ayer en los Oscar, por ejemplo) para volver a ver uno de los mejores finales de la historia del cine. youtu.be/g4ODPyUxLNw?...

Looks interesting, plasmid assembly from multiple metagenomes "On synthetic benchmark datasets, PlasMAAG reconstructed 50-121% more near-complete plasmids than competing methods and improved the Matthews Correlation Coefficient of geNomad contig classif. by 28-106% www.biorxiv.org/content/10.1...

"An assault on science and scientists anywhere is an assault on science and scientists everywhere."

Cardiometabolic benefits of a non-industrialized-type diet are linked to gut microbiome modulation: Cell www.cell.com/cell/fulltex...

This will be a really exciting webinar, don't miss it if you are working in the AMR genomics field

Hey genomics community, @sandrareuter.bsky.social and I will be leading the one on the 27th March so join us for an interactive workshop on genomics!

Polémica planta de biogás proyectada en Colmenar Tres Cantos - Los problemas con los residuos crecen si no escuchamos a la ciencia ni a la ciudadanía. #biogás #cambioclimatico #fernandovalladares #lasaluddelahumanidad #macrogranja #airelimpionorte #trescantos #colmenarviejo

Evaluating Agar-Plating and Dilution-to-Extinction Isolation Methods for Generating Oak-Associated Microbial Culture Collections #ISMEComms from @jamesemcdonald.bsky.social academic.oup.com/ismecommun/a...

Our paper describing the microGWAS pipeline was published yesterday in Microbial Genomics. Lots of fixes and additions to the code/documentation since the preprint, including a hard to reproduce bug that only showed up in a specific HPC 🥵 www.microbiologyresearch.org/content/jour...

Excellent by @paulkrugman.substack.com.web.brid.gy on the Trumpian war on science in the USA, and how it has killed, and will kill hundreds of thousands open.substack.com/pub/paulkrug...

The Kalamari paper is finally out! (I mainly use it as a database, but I know it has other cool features)

The overview of AMR that you always wanted (someone else to write) - amazing! Truly brilliant paper with great figures! @lancetmicrobe.bsky.social www.thelancet.com/journals/lan...

🚨 🧬 Updated preprint on the completed BASEL collection - what's new? Some fun with bacterial immunity and a new P22 relative infecting E. coli K-12. A thread 🧵

New pre-print!!! What types of genes end up on plasmids and why? The take home message of this paper is that beneficial genes move from plasmids to chromosome, causing the ecological value of plasmids to decay over time. www.biorxiv.org/content/10.1...

Qué razón tiene Conan O’Brien, hay que ir al Prado siempre que se pueda.