If you are wondering why on earth would neurons need cilia you should be there👀

If you’re at #sfn25 you definitely don’t want to miss this nanosymposium on cilia, tomorrow from 1-4pm! Come learn about neuronal cilia, they do some pretty cool stuff!

All fours boxes of mine have just safely (although very battered) arrived from Boston… Wow, now it feels like I’ve really left😔

The artist responsible for this is OakOak: www.instagram.com/oakoak_stree...

Always a fantastic read from the Harvey lab- neurons projecting to the same area take on specialized network structures that enhance information transmission to downstream regions, and, guess what, they also guide accurate behaviors! (big fan of their graphics😉) rdcu.be/ePS0W

Which human brain circuits are implicated in neurodevelopmental conditions? We bridged human genetics, spatial transcriptomics and neurodevelopment to discover the convergence of autism-associated genes in the developing human thalamus! www.biorxiv.org/content/10.1...

And here is the story after peer review. This work highlights our current approach, which is to use Piezo channels to uncover new areas of biology that are shaped by mechanical forces: www.science.org/doi/10.1126/...

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I’m totally biased but this is the best hand-pulled noodle in the entire world. The owners used to operate in Singapore, and they moved back to set up this place a decade ago. It’s one block away from my grandpa’s place, and amazingly they didn’t raise the price even during COVID times.

That's a cool behavior paradigm! (Ingenious analysis pipeline as well🤯) rdcu.be/ePgWw

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People familiar with the right and with media will immediately recognize James Watson’s path into full scientific racism. He followed a particular contrarian, trolling descent. According to this obit, he felt his biggest discovery was in his 30s, and later in life he searched for relevance. 1/

As someone who has had ~4h sleep on average during the past week- this sounds great🫠

happy to share our new paper, out now in Neuron! led by the incredible Yizhen Zhang, we explore how the brain segments continuous speech into word-forms and uses adaptive dynamics to code for relative time - www.sciencedirect.com/science/arti...

My quote of the day As I reflect on my life, I recognize that our greatest achievements often arise from our most profound struggles. Embrace challenges and view failures as opportunities for growth. It is through these trials that we learn, adapt, and ultimately succeed. Marie Curie

The last two cells I patched! They are by no means my best fills, but definitely the most memorable. Also a reminder to new patchers that lousy fills do not indicate bad cells- some of my best recordings didn’t have great fills. (Ah I miss patching🥹) #patchclamp #electrophysiology

Zohran Mamdani has won, & will be the next mayor of NYC.

New article from the lab out today, in which we discuss how social behavior evolves at the molecular level. From parenting across the animal tree of life to caste systems in social insects, it’s all connected (and, therefore, slowly starts to make sense)…

Glia gang, this is for you! In this video by our #ElectronMicroscopy team, shows a pyramidal neuron (PyC) surrounded by 8 glia brain cells – 5 microglia (MG) and 3 oligodendrocyte progenitor cells (OPC). 🧠📈 http://microns-explorer.org

A very informative and entertaining read! Zebrafish use spectral information to suppress the visual background: Cell www.cell.com/cell/fulltex...

Like every responsible adult, I got myself a jellycat while shopping for bathroom renovation stuff.

Landed in hometown airport! Proof that the air quality has much improved since @turrigiano.bsky.social ‘s last visit😉

Just landed in Hong Kong. Wow, I genuinely didn’t expect this to be read by so may. Thank you for everyone who liked, replied, and reposted, I will try to read through them during the layover. ❤️

After 13 years in the US, I’ve made the difficult decision to leave. Having packed up everything and rethought about priorities, rather painstakingly, while I’m sad to leave the life I’ve made here, I’m also relieved that I won’t have to plan my life around immigration policies anymore.

Look at that👏👏👏

Donated some of my books to one of my favorite public libraries- love the view from this courtyard!

I’m biased but if you are going to SfN, you don’t want to miss @strontiumpup.bsky.social’s cool results👀

Happy to share that our BBS target article has been accepted: “Core Perception”: Re-imagining Precocious Reasoning as Sophisticated Perceiving With Alon Hafri, @veroniqueizard.bsky.social, @chazfirestone.bsky.social & Brent Strickland Read it here: doi.org/10.1017/S014... A short thread [1/5]👇

Time for us to develop a new ethological behavior: bat hunting

TT faculty job opening in #Neuroscience! We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply academicjobsonline.org/ajo/jobs/30961

One of the most beautiful things in the world❤️ #patchclamp #EIRatio

Despite the mess, we are grateful to be funded, have exciting science happening, and have an opening for a postdoc! If you are interested in sensory biology and esp in cilia, thermosensation, or interoception, and would like to join an interactive & supportive group - please email. Please RT 🙏

Excited to share our new #biorxivpreprint: “Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1... We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10

How cool is that!🤯🤩

I am proud to share that our work of 4+ years has finally been published. We wondered if there are distinct behaviors that mark sleep in 🪰, where sleep has been defined as prolonged immobility. 🔗 www.science.org/doi/10.1126/...

Bringing some more ExM to #FluorescenceFriday with what appears to be a frustrated cell division in fibroblasts. More details in Alt-text.

The brain is incredibly densely connected. Human cerebral cortex may have as many as *one trillion* connections. Most of those cortical connections are recurrent, inside each area. What do they do? New paper from me in Annual Reviews: 🧪 🧠📈 1/ www.annualreviews.org/content/jour...

🚨Our preprint is online!🚨 www.biorxiv.org/content/10.1... How do #dopamine neurons perform the key calculations in reinforcement #learning? Read on to find out more! 🧵

A far-red dopamine sensor unlocks multiplex views of in vivo neuromodulation — a Tools of the Trade article by Yu Zheng #neuroscience #neuroskyence www.nature.com/articles/s41...

Finding correlates of the same signal in different brain areas is not evidence against specialisation, it is evidence for interconnection. When I flush my toilet, the level in the tank and the flow rate in the supply pipe become perfectly correlated. Yet these toilet areas have distinct functions.

super cool. another crack in the genome-centric paradigm,& a great example of Alfonso Martinez Arias’s argument in “The Master Builder." I look forward to anything @philipcball.bsky.social might write about this! (Disclaimer: all posts represent personal views only) www.nature.com/articles/s41...

When neurons change, but behavior doesn’t: Excitability changes driving representational drift New preprint of work with Christian Machens: www.biorxiv.org/content/10.1...

Check out the latest volume of the Annual Review of Neuroscience 🧠 Take a look at the table of contents arevie.ws/44K8QJZ

1/10 Our latest research, led by Monika Moissidis, identifies a mechanism regulating the maturation of PV interneurons in the #cortex. This is the story @cellcellpress.bsky.social www.cell.com/cell/fulltex... ⬇︎ thread @devneuro.bsky.social @kingsioppn.bsky.social @wellcometrust.bsky.social

Children are incredible language learning machines. But how do they do it? Our latest paper, just published in TICS, synthesizes decades of evidence to propose four components that must be built into any theory of how children learn language. 1/ www.cell.com/trends/cogni... @mpi-nl.bsky.social

🚨 New opinion piece written with Tara Keck 𝘐𝘯𝘵𝘦𝘳𝘢𝘤𝘵𝘪𝘰𝘯𝘴 𝘣𝘦𝘵𝘸𝘦𝘦𝘯 𝘩𝘰𝘮𝘦𝘰𝘴𝘵𝘢𝘵𝘪𝘤 𝘱𝘭𝘢𝘴𝘵𝘪𝘤𝘪𝘵𝘺 𝘢𝘯𝘥 𝘴𝘵𝘢𝘵𝘪𝘴𝘵𝘪𝘤𝘢𝘭 𝘭𝘦𝘢𝘳𝘯𝘪𝘯𝘨: 𝘈 𝘳𝘰𝘭𝘦 𝘧𝘰𝘳 𝘪𝘯𝘩𝘪𝘣𝘪𝘵𝘪𝘰𝘯 rb.gy/m862ik It's part of a special issue born from an unforgettable science extravaganza hosted by @kitp-ucsb.bsky.social in Santa Barbara🌴🧠 1/🧵

I read about embryonic patch clamp this morning and I'm still thinking about and being amazed by that work🤯

We began a pilot experiment. Lots of sciencey excitement! Then, (pole)catastrophe. Something weaseled into the barn and started killing mice. It kept coming back until it was caught and ID'd: a polecat with a rude demeanor, an appetite for small mammals, and exceptionally bad scientific timing 8/11

The phenomenon you're seeing here is sometimes called a "fire rainbow", which is a misnomer, but beautifully descriptive of a cloud on fire with color. This is actually the result of light passing through flat, hexagonal plates of ice suspended in clouds. Let's talk about circumhorizontal arcs.