Congratulations, Yifan, for the Anatrace Award! Yifan’s work on the TRPV1 structure with David Julius helped launch the Resolution Revolution in cryo-EM. Not just in membrane proteins—hardly any area of biophysics today has remained untouched by the techniques Yifan pioneered.

Congratulations, Nuria! For many years, Nuria ran the Biochemistry and Biophysics of Membranes study section at the NIH. She trained generations of reviewers and taught many of us how to write a better grant.

🚨🧠🔬 A major breakthrough in molecular neuroscience: I am excited to share a new story from our lab, published in accelerated format today by @nature.com: "Delta-type glutamate receptors are ligand-gated ion channels" Read more here (free article link): rdcu.be/eGIKz

Re-upping this - applications will close - open to UK-based people too!!!

Three Associate Professor (or Professor) positions available at Oxford Biology. Come be my colleague! www.biology.ox.ac.uk/article/we-a...

Did you hear? Biophysical Society has expanded its Bridging Funds Program, to support community members who are experiencing funding challenges. Learn more about how to apply or donate to the program www.biophysics.org/blog/biophys...

Get important feedback from your community and move your work forward. Share your research at #bps2026! Submit an abstract today buff.ly/oOjstk6

Mitochondria finally made the headlines, yay! Oh wait, ... oh no ....

We're Hiring! Assistant Professor of Molecular Therapeutics in MCB. Learn more and apply online: aprecruit.berkeley.edu/JPF05098

"What I would simply say is cancer can't wait." --Richard Schlueter, a 56-year-old metastatic cancer patient whose therapy was delayed due to terminations at NIH.

Several people have suggested that I compile my emails to Bhattacharya and I am delighted to do so. Announcing the first cut of "Fifty Shades of 'Jay' jeremymberg.github.io/jeremyberg.g... This contains just the first few exchanges. I will be adding more as time permits.

We are deeply saddened to share that our friend and colleague Jim Hudspeth passed away on Saturday. We will remember and continue to be inspired by Jim’s integrity, his humility, and his unwavering commitment to discovery.

$400M more for NIH in FY26 helps to improve the lives of all Americans. Join us in thanking the senators on the Appropriations Committee! Click to send a letter: ow.ly/VIte50WEKY4.

It was such a pleasure to attend this celebration: “The Structure of Bacteriorhodopsin 50 Years On: Electron Cryomicroscopy and the Dawn of Membrane Protein Structural Biology.”

Want to share your work at the premiere meeting of the minds between basic membrane biology and therapeutics? Short talk deadline is coming up Oct. 8, 2025. www.keystonesymposia.org/conferences/...

Absolutely outrageous interference in NIH extramural funding by OMB dropping this evening. Damaging to our nation’s world leadership, innovation, and training today and for years in the future. www.wsj.com/politics/pol...

Thoughts from our own Tom Rapoport on the role of basic science in curing disease. magazine.hms.harvard.edu/articles/rev...

If you are going to M&M, also see postdoc @joshdcryoem.bsky.social's poster about tilted vs untilted data collection for in situ structural biology www.sciencedirect.com/science/arti....

Did you know about the BPS Bridging Funds Program? If you're a biophysicist navigating a difficult time, this program is for you to defray costs for attending the BPS Annual Meeting! I am grateful to the @biophysicalsoc.bsky.social for supporting our members! www.biophysics.org/2026meeting/...

Announcing the new SGP Rising Star Travel Awards for students and postdocs. The $500 awards can be used for meetings held up to 1 year from notification. Apply today! Deadline: 1 August 2025 sgpweb.org/awards/risingstar

No better time to call or email your members of Congress. Next year’s NIH budget is being debated in the Senate. A new nonpartisan campaign is making it easy to defend science and protect America’s innovation. Just follow this link to contact your representatives: www.protectscienceandinnovation.org

The 2025 Google Scholar metrics are out. And (as previously) one of my favourite journals (Biophys J) is highly ranked in Biophysics. Only the 5 most cited papers are actually not Biophys J papers but rather BPS abstracts published elsewhere Beware of metrics scholar.google.com/citations?hl...

LMB Director Jan Löwe welcomes UK Global Talent Fund announcement: "Global talent has always driven LMB breakthroughs. We welcome efforts to remove barriers for researchers wishing to relocate - diverse minds fuel innovation and helps us stay globally competitive." tinyurl.com/3wahmr27 #LMBinthenews

Another chance to join the amazing @mrclmb.bsky.social with its generous core funding that allows it scientists to perform world-leading science, and with the best research culture you'll have ever experienced! 🤩

Reconnect with your community next February in San Francisco! Catch up with colleagues, make connections, and get important feedback on your work at #bps2026

President Trump and his Administration are making cuts to critical programs at NIH, including Diabetes Prevention studies, and hurting the agency’s ability to operate. I urged my Republican colleagues to help the families in front of us today by protecting NIH funding.

When I arrived to NYC as a postdoc, NYSBDG was my first local meeting, and I was blown way by the world-class quality of the science. It's a great opportunity to meet the local #structbio & #cryoem community, and it's coming up in two weeks, so register now at the eventbrite link below!

Considering a PhD in molecular biology? There’s still time to apply to join the LMB in October 2024. Applications close on 3rd DEC. Visit our website for more info: www2.mrc-lmb.cam.ac.uk/students/int...

Wow! Deep Mutational Scan of NaCT!! www.science.org/doi/10.1126/... Valuable to biochem. understand NaCT folding & function, and clinical VUS in SLC13A5-Epilepsy Beautiful study and Herculean effort by Wen-An Wang and REsolution colleagues in @supertifurgalab.bsky.social at @cemm.oeaw.ac.at

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages. ki.se/en/about-ki/...

Attending the NYC #CryoEM meeting today - looking forward to a fantastic day of science! Thanks @fravallese.bsky.social & Bill Rice for organizing a great meeting, and looking forward to a keynote from Ed Twomey @cryoet.bsky.social this arvo! 🗽❄️🔬

New preprint from Daniel Du @fitzpatricklab.bsky.social shows #femtosecond light pulses can lens electron beams, promising higher contrast in #cryoET and better aberration correction in #cryoEM tinyurl.com/257sw7j9 Experiments made possible by support from @cziscience.bsky.social #ImagingTheFuture

We are hiring a new editor! If you want to join the Nature Structural & Molecular Biology team and help publish exciting research, please apply. Deadline is June 20th. springernature.wd3.myworkdayjobs.com/SpringerNatu...

Join our group in the Centre for Medicines Discovery at Oxford Univ. @cmd.ox.ac.uk @ox.ac.uk !!!! Happy to chat about any questions about the role and science. Oxford will assist with a skilled worker visa. Please RT! my.corehr.com/pls/uoxrecru...

Two Harvard economists forecast the impact of the administration’s proposed NIH budget cuts- stunning losses in new therapies, life expectancy, and economic output with a “social cost 16 times greater than the savings the administration is attempting to achieve." jamanetwork.com/journals/jam...

25 years ago, I came to Stanford on a J1 visa and worked so hard to be worthy of that privilege. Today, I lead Immunology at Mount Sinai and I am the one who feel privileged when brilliant international trainees chose to join us.

Hundreds of National Science Foundation staffers turned out for a group photograph to celebrate the besieged agency’s 75th anniversary—despite efforts by NSF officials to prevent the picture from being taken. scim.ag/4jcGpIt

ICYMI: New online: How we peer review structural data

Today is SLC13A5 Epilepsy International Awareness Day, I'm reminded in an email this morning from Kim Nye, founder of TESS Research Foundation. Read more here: www.tessresearch.org/awareness/ and …

“Undermining the future of American science is not a path to accountability — it’s a path to decline.” In a powerful new piece, my colleague Daphna Shohamy explains how canceled grants are driving young scientists out of science—and out of the country. 🔗 www.statnews.com/2025/05/07/u...

Been thinking about biomembranes? Wondering what next decade of research will be? Wonder no more: there's an awesome conference coming up in Copenhagen in July!! From simulations to cells and everything in between. 5 days left to submit abstract - APPLY! www.biophysics.org/blog/beyond-...

>20 years ago, Zuker et al. discovered the mammalian sweet taste receptors Now, an exciting collaboration between our labs reveals the #cryoEM structure of the human sweet receptor-key to sweet taste perception-online @cp-cell.bsky.social! www.sciencedirect.com/science/article/pii/S0092867425004568

Whatever Joan Miró was trying to express, to me this painting depicts neurotransmitter vesicle fusion at the synapse. Even the postsynaptic density is present—only the SNARE complexes are in the wrong location.

OK inspired by @karalmarshall.bsky.social I am reaching out to the public where ever I can. Traditionally Republicans have been incredibly supportive of science. We as scientists need to reach out to people across the spectrum to rally their support for basic science!

Two additions to this: 1. Last day for registration is *May 16th*, so act fast!! & 2. Ed Twomey (@cryoet.bsky.social) will be giving the keynote! Should be a fantastic meeting, see all you #nyc #cryoem folks there June 25th!! Register at link below: 👇

What happens when the world’s leading funder of medical research faces aggressive budget cuts? 60 Minutes reports, tonight.

I'm excited to share our lab's newest publication on the structure and pharmacology of human GABA transporter 3 @natcomms.nature.com. Much to our surprise, GAT3 adopts an inward-open conformation in complex with the (moderately) selective antagonist SNAP-5114. 💊 🧪 #CryoEM #OpenAccess rdcu.be/ei2KY

SGP is excited to invite proposals for thematic meetings for the years 2027 through 2029. These meetings will provide a platform for researchers to engage in meaningful discussions on critical topics within the field of physiology. Deadline: 1 June 2025 bit.ly/sgp_meeting_....