Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n openrxiv.org/enabling-rev...

🌶️Publication Alert📢: Introducing #XL_MS, a workflow for enrichment of PhoX crosslinked peptides using #MagReSyn_Zr_IMAC from #TeamReSynBio but adapted for plant research! @pascalalbanese.bsky.social and team help decipher thylakoids and photosynthesis! doi.org/10.1101/2025...

Building the next generation of kick-ass women in marine science, one expedition at a time. #mesocosm @embl.org

Your sleep pressure is powered by your mitochondria! Sleep, energy, and ageing are all connected through mitochondrial bioenergetics in neurons. Brilliant work from Gero Miesenböck’s lab, just out in Nature @nature.com www.nature.com/articles/s41...

Science builds bridges🇮🇷🤝🇮🇱 Join me in welcoming our new postdoc Vida who brings PhD in plant sciences and will contribute to new bioenergetic studies. Vida is from Tabriz where her family's lives were disrupted by war. Thankfully no casualties, but career delays to her siblings and psychological toll

Folddisco detects (partial) motifs, allowing for substitutions and angle-length variations, by utilizing an index storing all residue pairs within 20Å encoded as geometric features. For space efficiency, it omits positions and compresses ids through run-length encoding (1.4TB for 53M structures) 2/9

Bluesky needs more music, and the world needs more nerds. This, ladies and gentlemen, is a blast from the past. And a reminder not to underestimate the chemists 😉. #chemsky youtu.be/f8FAJXPBdOg?...

Remarkable paper explaining how sea slugs maintain chloroplasts obtained by kleptoplasty active for many month & eventually digest them for resources www.cell.com/cell/fulltex...

Free structural MS hands-on workshop @ BIOCEV (CZ) 📅 Sept 15–19, 2025 For PhDs, postdocs & undergrads (CZ/SK) HDX-MS, native MS, cross-linking, high-res MS, data processing Apply by July 31 → bit.ly/3HNyzIg @spidocs.bsky.social @mbuavcr.bsky.social @ciisbinstructcz.bsky.social

Remember, everything Netanyahu does is to keep himself out of prison. For the sake of one crook's liberty, tens of thousands of people have been murdered, and now a possible full-scale war has been provoked. Israel must rise up and unseat him.

I'm happy to say that our new paper (and the first one out of my PhD thesis) is out! We describe the CryoEM structure of the phycobilisomes expressed during far-red light photoacclimation, and try to make sense of why these cyano are fond of "minimalism" :) doi.org/10.1038/s420...

90% of you probably don’t need to read this. But maybe some of you are curious & 10% will feel seen. Or a little less alone. This isn’t about seeking sympathy. It’s about sharing something hard to say out loud; partly to heal, partly in case someone needs to hear it too. (1/3) tinyurl.com/DudinO

Problem cryo-ET structure alert. A recent paper by Lange et al. in @natcellbio.nature.com (tinyurl.com/38s6a4dn) reported an unusual-looking model of the prohibitin complex in situ. We asked: how was this structure generated? Our reanalysis offers an explanation: tinyurl.com/mszdtwxx 🧵

To all #ChlamyDataset enthusiasts, here is a script that lets you directly import the pre-processed results from EMPIAR-11830 into #RELION v5 for subtomogram averaging: github.com/Chromatin-St... #Chlamydomonas #TeamTomo #CryoET #OpenSoftwareAcceleratesScience

"Our LPD-3 complex structural data reveal protein–lipid interactions that suggest a model for how the native LPD-3 complex mediates bulk lipid transport and provides a foundation for mechanistic studies of bridge-like lipid transport proteins (BLTPs)." 🤯🤯😍 www.nature.com/articles/s41...

TREC is now on Bluesky! The expedition has gathered samples all along Europe’s coasts – now scientists are exploring what the data tell us. We’ll be sharing insights into this amazing ongoing work! Spread the word! @embl.org @taraoceans-science.bsky.social @embrc-eu.bsky.social 📸Massimo Del Prete

Biochemist Nick Lane on the body electric ⚡ and the cycle that drives all carbon based life-forms on earth 🍃🌍 youtu.be/vBiIDwBOqQA #KrebsCycle #Complexity #Science #Biochemistry #Life 🧬🦠🔬

"Wound wood" is ecological engineering by the Earth Mother at its best! The tree seals the damage, fungi move in, beetles make tunnels, and here, Anolis carolinesis (green anole lizards) use it for a home. Decay signals transformation, not THE END. #WoundWood #Trees #Naturalist #botany #photography

Metabolites are not genes — avoiding the misuse of pathway analysis in metabolomics www.nature.com/articles/s42...

Pretty much everything is fucked, but here is some beautiful and exciting science from @archaeon-alex.bsky.social and colleagues. www.science.org/doi/10.1126/...

#HeardToday “You can’t solve mechanisms with genomics. For that you need to go to the trenches and do BIOCHEMISTRY!”

🌿Join us for the 2025 congress of the French Society of Photosynthesis in Paris May 26–28! 🌱 Exciting sessions on a broad range of topics related to photosynthesis. 📌 Abstract deadline: March 31 ✨ Free registration for students & postdocs 😁 👉 mfp2025.sciencesconf.org?lang=en #Photosynthesis

Who does that? We rented a train JUST for the conference, that will take the participants from Prague to the woods of Bohemia. There'll be talks ON THE TRAIN. In Prague we'll have 5 locations with different atmospheres. #theconferencetoendallconferences Register now: woodstock.img.cas.cz

MITOtalks this week

IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply now to our group leader position. The deadline is May 28. Link is below.

And now to something completely different: the response of an anaerobic archaeon to oxidative stress. Tubular nanocompartments encapsulate virus-like particles! Great work by Wenfei Song and many colleagues from @bijvoet-centre.bsky.social and @mib-wur.bsky.social. www.biorxiv.org/content/10.1...

The final version of our work on the in-cell architecture of the mitochondrial respiratory chain is now online in @science.org 🎉 You can find the full story here www.science.org/doi/10.1126/... @verenaresch.bsky.social did a wonderful job on the cover and animation, she really brought it to life 👩‍🎨

𝐅𝐨𝐜𝐮𝐬𝐞𝐝 𝐫𝐞𝐯𝐢𝐞𝐰📚 Decoding genetic diversity through genome engineering in bryophytes 📖 doi.org/10.1111/tpj.... 🖊️ Ye, Luo, Liu, Cao et al This review explores genome engineering in bryophytes, unlocking advances in agriculture, biotech, and more. 🌿🔬

Makes sense

2 day change -1,400 (always a tweet)

The low-res challenge is key for emerging cryo-ET data. 🔹 ROCKET extracts two conformations from a 9.6Å GroEL map. Its modeling matches humans here and even surpasses them in tough regions, boosting fit to data from CC=0.2 to 0.5 in a flexible domain (see ⭐) 7/14

In our latest review, we explore 12 deep-learning tools for metagenomic analysis, covering their strengths, limitations, and key applications. We hope it serves as both a resource and inspiration for new ways to analyze metagenomic data. Great work by Eli Levy Karin! 📄 doi.org/10.1093/nsr/...

Wow! 😵‍💫 Look at these membranes :) Finally some juicy plant 🌱 waffles 🧇

Our methods paper made it to bioRxiv: doi.org/10.1101/2025... Full #cryoET workflows for #plant tissues. Plus some general tricks and tweaks on serial Lift-Out and cryo-FLM. 🧪🧵1/5 #teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM #CLEM

🔬🎤 As pre-announced a few days ago... please let us proudly present to you: 𝑴𝒊𝒄𝒓𝒐𝕊𝒑𝒍𝒊𝒕 - your ticket to imaging more, imaging more gentle, and/or imaging more efficient. 🔬 doi.org/10.1101/2025... Like ❤️, repost 🔂, and most importantly... please send feedback ✉️ our way! 🙏

The news getting you down? I invite you to stare at this chart of solar and wind deployed capacity in China. They blew past their ambitious 2030 target... last July.

Today, we are publishing the first-ever International AI Safety Report, backed by 30 countries and the OECD, UN, and EU. It summarises the state of the science on AI capabilities and risks, and how to mitigate those risks. 🧵 Full Report: assets.publishing.service.gov.uk/media/679a0c... 1/21

Several single AA mutations increased the CO2 affinity! Given sequence divergence and different oligomeric states of Form I & II, we were surprised to find single muts led to CO2 affinity outside of the range of Form II & at the edge of the distribution of plants and algae (6/7)

What limits rubisco function? Is it the chemical mechanism? Evolution? In this paper, @prywes.bsky.social et. al explore this question by assaying >99% of single amino acid mutants in Form II rubisco (1/7) doi.org/10.1038/s415...

Is it just me or is the cover a bit cheeky? This bird's haircut reminds me of someone ...

POSTDOC POSITION AVAILABLE, Geneva, Switzerland - Applications are invited for a postdoc position to study UV-B perception and signalling in plants. Please apply, forward to suitable candidates, and/or repost; many thanks! Deadline February 24, 2025. See www.ulm-lab.ch for more information.

Time to end the vascular plant chauvinism - "Bryophytes...flourish in environments where even the hardiest vascular plant species cannot survive"...the diversity of bryophytes surpasses that of ferns, lycophytes and grasses #botany www.nature.com/articles/s41... #botany 🧪🌾

Come and join us for the workshop "Plant science in the Anthropocene" (PLANT), March 24th to April 4th 2025 @ University Paris-Saclay. Deadline for applications: Dec 17, 2024 #PlantScience

Did you know #diatoms are motile? These tiny glass cells have no cilia or flagella and a rigid body yet can glide on surfaces using a specialised slit in the cell wall called the raphe! What is the functional morphology of the raphe? All revealed in our new preprint www.biorxiv.org/content/10.1...

Hi Bluesky community! 👋 Are you looking forward to 2025 as much as we are? 👀 We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look! ➡️ s.embl.org/poster-bl #EMBLEvents #molecularbiology #lifesciencetraining

#Phytochromes: The 'eyes' that enable #microalgae to find their way in aquatic depths phys.org/news/2024-12... #Diatom phytochromes integrate the underwater light spectrum to sense depth: Carole Duchêne et al. www.nature.com/articles/s41... #Protists #ProtistsOnSky #Algae #Diatoms #Microbes

christoph: 𝘗𝘺𝘳𝘰𝘤𝘺𝘴𝘵𝘪𝘴 𝘯𝘰𝘤𝘵𝘪𝘭𝘶𝘤𝘢 (dinoflagellates) taking the lift in the water column like a pro (that it is, obviously) www.cell.com/current-biol... #ProtistsOnSky #MicroSky don't miss Video S1