Tesla doesn't recongise Trade Unions. Apple doesn't recognise unions. Amazon is anti-union. McDonald's is anti-union. Starbucks is anti-union. Google is anti-union. Walmart is anti-union. The big corporations are not on your side.

Hi all! We developed CAD-C to map chromatin organization at high res in yeast. It revealed an unexpected tight alignment: nucleosomes covering the same sequence tend to be associated across sister chromatids. www.biorxiv.org/content/10.6... #3DGenome #chromatin #Cohesin #centromere

CAD-C reveals centromere pairing and near-perfect alignment of sister chromatids https://www.biorxiv.org/content/10.64898/2025.12.18.694906v1

Ich habe das ungute Gefühl, dass das keine Konsequenzen haben wird. #Gießen #GI2911

Die Polizei ist komplett entfesselt! Sie kennt keine Zivilisation mehr: Schädel-Hirn-Trauma, offene Brüche, sehr viele Krankenwagen danach. Die Polizei ENTZIEHT den friedlichen Demonstrierenden sogar den Schutz. So ist ein Auto in eine Menge gefahren! Das Ganze muss ein Nachspiel haben!

Want to shape the future of genome science? 🧬 PhD positions available at Max Planck Institute & Uni Göttingen (IMPRS-GS/GönomiX)! Join a vibrant, interdisciplinary research community. Apply by Jan 14, 2026: www.uni-goettingen.de/de/applicati... #GenomeScience #Research

This is misinformation by default, so if you're a journal and you use AI slop for your cover or your announcements, you're not scientific in any way and should be shamed mercilessly 🧪

🧬 PhD Position: Evolutionary & Comparative Genomics 🕷️ Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13). We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes! More infos 👇 and s.gwdg.de/eDrAAY #Evolution #Genomics #Bioinformatics

Very excited to present OpenCGChromatin🔥🔥🔥 A new coarse-grained model that probes full chromatin condensates at near-atomistic resolution to reveal the molecular regulation of chromatin structure and phase separation Brilliantly led by @kieran-russell.bsky.social, with the Rosen and Orozco groups

POV: you are a young woman celebrating a recent academic success

🧬 10 @dfg.de-funded PhD positions at @goettingen-campus.de 🧬 ❗Focus: Evolution of gene regulatory networks & Wnt signaling in emerging models (insects, snails, flatworms, cnidarians). 💻 Methods: 'Omics, Bioinformatics, CRISPR/RNAi & Imaging. 📌Start: June 2026. #EvoDevo #Genomics #Bioinformatics

The Closing Scientific Retreat of @spp2202.bsky.social is under way in Goettingen with Gerd Blobel delivering the first Keynote lecture on LDB11-mediated looping of chromatin.

📢 Last days to apply for our #PhD and #MDPhD programs! Become part of Basel, Europe’s #LifeScience hub, and grow in a dynamic, international, and supportive community. Apply by Nov 15: www.fmi.ch/education-ca...

Our latest paper has just been published in Cell! doi.org/10.1016/j.ce... We developed a new method called MCC ultra, which allows 3D chromatin structure to be visualised with a 1 base pair pixel size.

JD Vance claims that diversity weakens unions, as people end up distrusting each other and not organizing. Let me tell you two menswear stories related to this claim. 🧵

Happy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....

Happy to report that the first part of my PhD work is published! Thank you to everyone involved!

"Genes, Traits, and Identities: Navigating Sex, Gender, and Sexuality in Modern Research" Frequently the trans and intersex communities are excluded from population-based genomics studies because they cannot be put in a neat box. But sex is a complex trait, like many other traits we study #ASHG25

Deutsche Hunger Games

Today I am so pleased to present our work on how chromatin remodelers affect mesoscale chromatin organization. www.science.org/doi/10.1126/...

Gesetzesnovelle von 700 Seiten: Grundrechtsfreundliche Politik vorbei. Nun biometrische Massenüberwachung & #Staatstrojaner für Polizei Berlin netzpolitik.org/2025/neues-p...

How do flexible regions of histone chaperones team up to handle histones? Together with Fred Winston’s lab @harvardmed.bsky.social, we reveal new insights in our study just out in Mol Cell. Hats off to James Warner and Vanda Lux @iocbprague.bsky.social for their key contributions! dlvr.it/TNB145

✨Exciting news: the main story of my PhD is out in Science! Together with Christine Moene @cmoene.bsky.social, we explored what happens when you scramble the genome—revealing how Sox2’s position shapes enhancer activation. 📖 Read the full story here: www.science.org/doi/10.1126/...

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene www.science.org/doi/10.1126/...

Congrats to my friends in the Boettiger lab for this really beautiful live imaging work. A big leap forward in understanding the dynamic side of genome organization. www.science.org/doi/10.1126/...

In kaum einem Land ist Vermögen so ungleich verteilt wie in Deutschland. Die reichsten zehn Prozent der Bevölkerung besitzen sagenhafte 11,4 Billionen Euro – und werden immer reicher. Sparen aber will die Regierung bei den Ärmsten. www.t-online.de/nachrichten/...

As part of this grant, I have a vacancy out for a PhD student to join our super nice team. It closes on September 9 (Tuesday). If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...

Our new preprint is out! We combined single-nucleosome imaging and 3D-SIM to reveal: 🔹 Euchromatin forms condensed domains, not open fibers 🔹Cohesin loss increases nucleosome mobility without decompaction 🔹Cohesin prevents neighboring domain mixing Full story & movies👇

Tabea Marx from the Department of Meiosis @schuhlab.bsky.social talks about the group’s ovulation research in the new SWR Wissen video (in German)! Why is ovulation research so challenging for scientists? What did the team find out? Watch the video to learn more👇 www.youtube.com/watch?v=UDz-...

Contributions of local structural and energetic features of DNA to large-scale genomic organization [perspective by Wilma Olson & Co) www.sciencedirect.com/science/arti...

#Preprint alert! 📣 We are thrilled to share the work led by Lara Zorro-Shahidian and Lucio di Filippo, in which we show that #MLL2 controls gene expression in both #ESC and upon #differentiation by facilitating the #enhancer like activity of #LINE1 elements www.biorxiv.org/cgi/content/...

Excited to share the latest work from the lab led by @eharo84.bsky.social, in which we have used synthetic biology to explore the mechanisms by which different types of long-range enhancers ensure robust and precise developmental gene expression www.biorxiv.org/content/10.1...

Excited to share our latest preprint. www.biorxiv.org/content/10.1.... Lead by Lukas, we investigated multiple ways of assessing a TF's sensitivity to chromatin based on genome-wide binding profiles. The developed methods allowed us to quantify chromatin sensitivity across tested TFs.

Excited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. www.sciencedirect.com/science/arti....

To all post-docs: The Genome Biology dept ‪@embl.org has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Wang et al, 2025. Genome-Wide Investigation of Transcription Factor Occupancy and Dynamics Using cFOOT-seq www.biorxiv.org/content/10.1...

🚨 New paper alert 🚨 I am excited to share our new work on epigenetic enhancer priming in early mammalian development genomebiology.biomedcentral.com/articles/10.... Fantastic collaboration with Wolf Reik’s team, with key contributions from many others, led by the excellent Chris Todd. Short 🧵

How do chromatin remodelers use #IDRs to find TF binding partners? In our new Molecular Cell paper, we show that β-catenin is an adaptor that links SWI/SNF (cBAF) subunit ARID1A with binding partners via IDR-domain interactions. www.cell.com/molecular-ce...

🎉 Join us at the upcoming GfG Symposium "Epigenetics & Chromatin" in Giessen, Sept 24–26, 2025! Amazing speakers, low registration fee, € 300 prizes for best poster & short talk, + free GfG membership for non-members. Please RT! express.converia.de/frontend/ind...

Our paper is now out in Molecular Cell! Check the thread in this former post: www.cell.com/molecular-ce...

The evolution of high-order genome architecture revealed from 1,000 species www.biorxiv.org/content/10.1... 🧬🖥️🧪 github.com/xjtu-omics/H...

I'm proud to announce the latest release of 🧬 #Oxbow 🏹, with new features to make NGS data analysis more powerful, efficient, and "composable". Learn more at: oxbow.readthedocs.io

(1/n) New preprint from @claricehongky.bsky.social Fan Fang Varshini Ramanathan in collab w Jie Liu. Q: How do we get ultra-high-res 3D genome maps? A: New deep learning model, Cleopatra. Cleo trains on Micro-C, fine-tunes on RCMC, and predicts genome-wide 3D maps at ultra-high resolution.

PSA: We just finished processing nearly all public ATAC-seq datasets from SRA (about 22,000 datasets). (Not?) Surprisingly, we had to throw-out nearly ~50% because they were low-quality (low signal-to-noise, duplicate rate, etc.). Check quality before analysis (TSS-enrichment is not sufficient!).

📢OUT TODAY @natgenet.nature.com 📰Single-cell Micro-C profiles 3D genome structures at high resolution and characterizes multi-enhancer hubs. By Honggui Wu, @Xiaoliang Sunney Xie and colleagues. ⬇️ www.nature.com/articles/s41...

Are you ready to boost your research career? Apply with @uniGoettingen for an #MSCA postdoctoral fellowship! We’ll gladly support your application, so get in touch asap: www.uni-goettingen.de/en/671766.html #EarlyCareerResearcher #PostdocCareers #Mobility #WeAreInternational Deadline 10 Sept.

It sounds hyperbolic, I know, but I genuinely believe that wikipedia incorporating LLM-produced article summaries, or sanctioning LLM-produced articles, would signal the end of the internet as we've known it.

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.