@ngoccao.bsky.social
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Congratulations to everyone ! ๐ฅณ Thank you so much Dr. Manel for your supervision during my master thesis! I am so happy to be part of this collaborative effort!
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4 months ago
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reposted by
Axel Delamarre
2 months ago
Our paper is now out in Molecular Cell! Check the thread in this former post:
www.cell.com/molecular-ce...
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I am excited and honoured to share that I was selected as a recipient of the ๐๐๐ฌ๐ญ ๐๐จ๐ฌ๐ญ๐๐ซ ๐๐ฐ๐๐ซ๐ at the ๐๐๐๐ ๐๐จ๐ซ๐๐จ๐ง ๐๐๐ฌ๐๐๐ซ๐๐ก ๐๐จ๐ง๐๐๐ซ๐๐ง๐๐ ๐จ๐ง ๐๐๐ง๐จ๐ฆ๐ ๐๐ซ๐๐ก๐ข๐ญ๐๐๐ญ๐ฎ๐ซ๐ ๐ข๐ง ๐๐๐ฅ๐ฅ ๐ ๐๐ญ๐ ๐๐ง๐ ๐๐ข๐ฌ๐๐๐ฌ๐ ๐. (see ๐งต below)
3 months ago
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reposted by
Babis Galouzis
4 months ago
Check our latest with Yacine Kherdjemil and
@eileen-furlong.bsky.social
and our colleagues, where we show Chip (Ldb1) is essential only at a narrow window of embryogenesis overlapping ZGA. It functionally and physically bridges CBP to Zelda to regulate gene expression.
www.cell.com/molecular-ce...
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Chip (Ldb1) is a putative cofactor of Zelda forming a functional bridge to CBP during zygotic genome activation
Chip/Ldb1 is a crucial cofactor regulating enhancer function and chromatin interactions. Using optogenetics, Galouzis, Kherdjemil et al. show that Chip is only essential during zygotic genome activati...
https://www.cell.com/molecular-cell/fulltext/S1097-2765%2825%2900457-5
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Congratulations to everyone ! ๐ฅณ Thank you so much Dr. Manel for your supervision during my master thesis! I am so happy to be part of this collaborative effort!
add a skeleton here at some point
4 months ago
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reposted by
Marieke Oudelaar
5 months ago
Congratulations to first authors Magdalena Karpinska and Yi Zhu and many thanks to all co-authors and the very helpful editors and reviewers! Special thanks to
@dariloops.bsky.social
for a great summary:
www.nature.com/articles/s41...
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Decoupling chromatin hubs from gene control - Nature Structural & Molecular Biology
Chromatin hubs, which are formed during cell differentiation, are characterized by simultaneous interactions between multiple regulatory elements and gene promoters. Research now shows that the disrup...
https://www.nature.com/articles/s41594-025-01544-2
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Congratulations to all! Thank you so much for including me in this work!
add a skeleton here at some point
5 months ago
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reposted by
Marieke Oudelaar
6 months ago
Many congratulations to *Dr.* Shyam Ramasamy for a fantastic PhD thesis & defence! A very well deserved summa cum laude ๐ฅณ
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reposted by
Romain Koszul
8 months ago
Our latest work: how can compartmentalization emerge in a eukaryotic genome lacking canonical heterochromatin? By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient!
#chromatin
#3Dgenome
#generegulation
www.science.org/doi/10.1126/...
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Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus
In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and a...
https://www.science.org/doi/10.1126/science.adm9466
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