Babis Galouzis
@babisgalouzis.bsky.social
π€ 311
π₯ 210
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Biologist into evolution and development EMBO fellow at EMBL
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Babis Galouzis
Michela Palamin
13 days ago
ChromSMF preprint is out!π
tinyurl.com/ChromSMF
We often piece together chromatin regulation layer by layer from separate assays. But this can be limiting! In
@arnaudkr.bsky.social
's lab, we developed a method to directly study multiple layers on the same DNA molecule! 𧬠What does this unlock? β¬οΈ
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Babis Galouzis
EMBL Events
18 days ago
At #EMBLTranscript, experts will share breakthroughs across the full spectrum of #transcription β from cis-regulatory function and long-range regulation to 3D looping, basal transcriptional machinery, #chromatin modifications, #epigenetic inheritance, and more 𧬠Join us:
s.embl.org/trm26-01-bl
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Babis Galouzis
Nikos Konstantinides
3 months ago
I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
add a skeleton here at some point
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This is so cool! Itβs also nice to see how careful genetic dissection of loci is still at the forefront of discovery!
add a skeleton here at some point
6 months ago
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Check our latest with Yacine Kherdjemil and
@eileen-furlong.bsky.social
and our colleagues, where we show Chip (Ldb1) is essential only at a narrow window of embryogenesis overlapping ZGA. It functionally and physically bridges CBP to Zelda to regulate gene expression.
www.cell.com/molecular-ce...
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Chip (Ldb1) is a putative cofactor of Zelda forming a functional bridge to CBP during zygotic genome activation
Chip/Ldb1 is a crucial cofactor regulating enhancer function and chromatin interactions. Using optogenetics, Galouzis, Kherdjemil et al. show that Chip is only essential during zygotic genome activati...
https://www.cell.com/molecular-cell/fulltext/S1097-2765%2825%2900457-5
10 months ago
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