Chris Clarkson
@chrsclrksn.bsky.social
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Bioinformatician working on tandem repeats
reposted by
Chris Clarkson
Nacho Molina
10 months ago
Time for a short thread! We developed HiddenFoot, a biophysics-inspired approach to decode single-molecule footprinting data and infer TF, nucleosome, and RNA Pol II binding profiles on individual DNA molecules. One molecule at a time!
www.biorxiv.org/content/10.1...
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reposted by
Chris Clarkson
Teif lab
12 months ago
We have a postdoctoral opening for a researcher with experience in bioinformatics of DNA sequencing and machine learning to work on the development of new methods for cancer diagnostics related to nucleosomes, chromatin and beyond
www.jobs.ac.uk/job/DMK060/s...
. Application deadline: 21st April 2025
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Senior Research Officer at University of Essex
Searching for an academic job? Explore this Senior Research Officer opening on jobs.ac.uk! Click to view more details and browse other academic jobs.
https://www.jobs.ac.uk/job/DMK060/senior-research-officer
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reposted by
Chris Clarkson
Daniel S. Goldberg
12 months ago
#vanitas
#memes
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Really interesting looking position- highly recommend!
www.jobs.gla.ac.uk/job/research...
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Research Assistant/Associate
Job PurposeTo contribute to/make a leading contribution to the project āSomatic instability in Huntington diseaseā working with Prof. Darren Monckton. Prof Moncktonās team use human genetic analyse...
https://www.jobs.gla.ac.uk/job/research-assistant-slash-associate-3?source=gla.ac.uk
about 1 year ago
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reposted by
Chris Clarkson
Kevin Mitchell
about 1 year ago
More thoughts on these issues here: If genomics is the answer, what's the question?
www.wiringthebrain.com/2018/12/if-g...
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If genomics is the answer, what's the question? A commentary on PsychENCODE
There was much excitement in the press and in the psychiatric research community recently as a flurry of papers was p...
http://www.wiringthebrain.com/2018/12/if-genomics-is-answer-whats-question.html
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reposted by
Chris Clarkson
Teif lab
about 1 year ago
Most previous epigenetic age predictors were focused on DNA methylation. Our own model suggested nucleosome positioning as an age predictor a year ago
onlinelibrary.wiley.com/doi/full/10....
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Aging clock based on nucleosome reorganisation derived from cellāfree DNA
We show that aging is associated with an increase in the distance between nucleosomes, which can be used to predict a person's age and conduct age classification. We developed the first aging clock b...
https://onlinelibrary.wiley.com/doi/full/10.1111/acel.14100
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reposted by
Chris Clarkson
Nature Portfolio
about 1 year ago
An essay in Nature discusses how itās an astonishing achievement that all of statistics and much of science depends on probability considering no oneās sure what it is. š§Ŗ
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Why probability probably doesnāt exist (but it is useful to act like it does)
All of statistics and much of science depends on probability ā an astonishing achievement, considering no oneās really sure what it is.
https://go.nature.com/3P2umAV
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The lab of (amazing!) Arianna Tucci and I are delighted to share our published work on the repeat expansion locus in THAP11:
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https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.30073
over 1 year ago
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reposted by
Chris Clarkson
Jeremy Allen
over 1 year ago
My fav starter packs so far, a thread: stats:
go.bsky.app/Ki7PjpS
stats:
go.bsky.app/7TBN5rX
causal inference:
go.bsky.app/FdemGAZ
package devs:
go.bsky.app/N1569Qh
data peeps:
go.bsky.app/8TdEfdK
medical stats:
go.bsky.app/ArqEz36
bioinformatics:
go.bsky.app/Ha64Gmv
r-ladies:
go.bsky.app/Vgxwa2F
add a skeleton here at some point
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reposted by
Chris Clarkson
Kurianlab
over 1 year ago
www.biorxiv.org/content/10.1...
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RNA editing is a molecular clock in unmodified human cells
Despite major advances in spatial RNA sequencing, the ability to extract temporal information in RNA sequencing experiments is still limited. Here, we describe Transcriptome Timestamping (T2), a syste...
https://www.biorxiv.org/content/10.1101/2024.11.18.624170v1
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