Nucleosome aficionados! Our new review "Nucleosome spacing across cell types, diseases, and ages" is out in NAR: academic.oup.com/nar/article/... A huge effort to pull together what we’ve learned about nucleosome spacing in many systems. Enjoy! @milena-bikova.bsky.social @chrsclrksn.bsky.social

Time for a short thread! We developed HiddenFoot, a biophysics-inspired approach to decode single-molecule footprinting data and infer TF, nucleosome, and RNA Pol II binding profiles on individual DNA molecules. One molecule at a time! www.biorxiv.org/content/10.1... 1/6

We have a postdoctoral opening for a researcher with experience in bioinformatics of DNA sequencing and machine learning to work on the development of new methods for cancer diagnostics related to nucleosomes, chromatin and beyond www.jobs.ac.uk/job/DMK060/s.... Application deadline: 21st April 2025

#vanitas #memes

Really interesting looking position- highly recommend! www.jobs.gla.ac.uk/job/research...

More thoughts on these issues here: If genomics is the answer, what's the question? www.wiringthebrain.com/2018/12/if-g...

Most previous epigenetic age predictors were focused on DNA methylation. Our own model suggested nucleosome positioning as an age predictor a year ago onlinelibrary.wiley.com/doi/full/10....

An essay in Nature discusses how it’s an astonishing achievement that all of statistics and much of science depends on probability considering no one’s sure what it is. 🧪

The lab of (amazing!) Arianna Tucci and I are delighted to share our published work on the repeat expansion locus in THAP11:

My fav starter packs so far, a thread: stats: go.bsky.app/Ki7PjpS stats: go.bsky.app/7TBN5rX causal inference: go.bsky.app/FdemGAZ package devs: go.bsky.app/N1569Qh data peeps: go.bsky.app/8TdEfdK medical stats: go.bsky.app/ArqEz36 bioinformatics: go.bsky.app/Ha64Gmv r-ladies: go.bsky.app/Vgxwa2F