Excited to share that a part of my PhD work is online now on BioRxiv! www.biorxiv.org/content/10.6... We developed a genome editing approach to target the JAK2 V617F mutation and demonstrate its potential to alleviate MPN hallmarks in primary patient cells. Thread 👇

Thanks so much for highlighting our images created with @rcollepardo.bsky.social

#WIMMReads: Oxford scientists, led by James Davies at the MRC WIMM, have captured the genome’s structure in unprecedented detail. 🧪 Read the full story below 👇 @ox.ac.uk @davieslab.bsky.social @jojdavies.bsky.social @medsci.ox.ac.uk

Our new preprint 🧬🔗 www.biorxiv.org/content/10.1... BRD4-NUT forms liquid-like condensates that locally constrain nucleosomes via BRD4-mediated crosslinking— physical control of #chromatin by #LLPS transcription condensates. @semeigazin.bsky.social @katsuminami.bsky.social @masaashimazoe.bsky.social

We’re really excited to see Hangpeng Li present our latest work at the CSH Mechanisms of Eukaryotic Transcription meeting.

In Brief: A new center in San Francisco will offer tailor-made CRISPR therapies to cure children with rare diseases www.nature.com/articles/s41...

Thrilled that our paper is in print @science.org!! *Platelets sequester cell free DNA, including free fetal and tumour-derived DNA* Tweetorial from @l-cmurphy.bsky.social below. Check out the news feature science.org/content/arti... and terrific editorial from Dennis Lo #platelets_in_the_limelight

⚡️Thrilled that #VirtualLab is published in @nature.com! www.nature.com/articles/s41... We created a team of AI agents to mirror my Stanford lab 🤖. Led by a PI agent, the AI scientists ran their own group meetings and discovered effective binders to new CoVID variants that we validated.

Great news for the Advanced Proteomics Facility based here in Biochemistry @ox.ac.uk ! The Wolfson Foundation is supporting the acquisition of a state-of-the-art mass spectrometer – the first of its kind in the UK – opening up possibilities for breakthroughs in human health ⬇️ bit.ly/202507-apf