Our collaborative paper with the Arndt lab is out today: doi.org/10.1093/nar/... (originally bioRxiv: www.biorxiv.org/content/10.1...). Here we asked the question of how CHD1 localizes to chromatin.

Excited to see this work published online at @cp-cell.bsky.social today! www.cell.com/cell/fulltex...

The Vlaming lab is expanding! If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat... My biased opinion: exciting topic, super nice colleagues, and great research environment in a lovely city.

🎉 Thrilled to share our new paper in @narjournal.bsky.social! We uncover how the Hox TF Ultrabithorax controls alternative splicing to shape muscle patterning and homeotic identity 🧬 @igmm-montpel.bsky.social 🔗 doi.org/10.1093/nar/...

We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease. www.nature.com/articles/s41...

Much appreciate the spotlight on our (‪@adelmanlab.bsky.social‬) paper about INT depletion/dsRNA-induced stress responses by @hanzlikovalab.bsky.social Amazing to see the finding being placed in perspective of the big picture of neurodevelopmental diseases and therapeutic targets 🙏 #RNABiology

Do you or someone you know have an exciting new chromatin/transcription story that you'll be ready to talk about in the Fall? Then fill out or share this form to speak in the @fnucleosome.bsky.social seminar series! All models, organisms, and complexes welcome 🧬🧪🔬

Exciting new work from Apoorva Baluapuri of the Adelman lab! @baluapuri.bsky.social @adelmanlab.bsky.social www.sciencedirect.com/science/arti...

Thrilled to see my work with @adelmanlab.bsky.social on INT/dsRNA highlighted by @willgarland.bsky.social and @heick.bsky.social ! Thanks for beautifully capturing how nuclear RNA guardians prevent cellular chaos. The ripple effects of transcriptional dysregulation are indeed profound! #RNABiology

Join us next Wed, for three amazing ECR researchers_ @fueyoraquel.bsky.social, @kaiamattioli.bsky.social and Laura talk about their work in #FragileNucleosome seminar series! In case you haven't joined any of the previous 2025 sessions, here is registration link: us06web.zoom.us/webinar/regi...

Why are there intronic reads in your bulk RNA-seq data? You're not alone—it's common, and the reasons are more layered than you think. Let’s break it down. 🧵

Sometimes when I am having a bad day I remember that after my TED talk in 2016 this woman mobbed me afterwards and threw herself on me with the hugest hug saying "Oh my god you were incredible and inspirational I want to BE you" It was Cher

Was great presenting at @fnucleosome.bsky.social - amazing feedback and participation from the audience. Thanks once again to the organizers:) here’s the link press release for the story for those who missed it : hms.harvard.edu/news/what-ha...

Read all about Apoorva Baluapuri’s new work on Integrator (INT) in HMS News! @baluapuri.bsky.social @adelmanlab.bsky.social tinyurl.com/y2fx22c2

You can read our full Review @science.org here 👉👉https://www.science.org/doi/10.1126/science.adp2959

Looking forward to share my postdoc work done with @adelmanlab.bsky.social, and to revisit @fnucleosome.bsky.social as a presenter once more after 3 years !!! Super excited….

Thanks @mpi-ie.bsky.social for the having me over last week and for the great conversations I had at your nice institute cradled in the beautiful Schwarzwald !!

Another McGill Assistant Professor job at the Lady Davis Institute (where I am)! This is for an immunology (host-virus interactions) position! Come by my colleague! mcgill.wd3.myworkdayjobs.com/en-US/McGill...

🧵 Want to automate bioinformatics tasks? Start by mastering one of the most powerful tools: the for loop in bash. I know I posted about GNU parallel :) but even "for loops" have a lot to learn Let’s go.

Evidence of substrate control of Cdk phosphorylation during the budding yeast cell cycle

Thrilled to see my postdoc work at Adelman Lab @hms-bcmp.bsky.social on Integrator(INT) now out @cp-cell.bsky.social. We found that INT deficiency allows immature+unlicensed RNAPII to precociously enter genes. This immature RNAPII can transcribe short genes but terminates prematurely in long genes:

Excellent opportunity available for a motivated #postdoc to join @kellythd-nguyen.bsky.social’s group investigating the roles of histones in regulating telomerase using a multi-disciplinary approach. More details: www.nature.com/naturecareer... Apply by 04 MAY #PostdocJobs #ScienceJobs

Now online! Integrator loss leads to dsRNA formation that triggers the integrated stress response

Thrilled to see my postdoc work at Adelman Lab @hms-bcmp.bsky.social on Integrator(INT) now out @cp-cell.bsky.social. We found that INT deficiency allows immature+unlicensed RNAPII to precociously enter genes. This immature RNAPII can transcribe short genes but terminates prematurely in long genes:

Excited to be at @keystonesymposia.bsky.social for first time ! Looking forward to plenty of science&fun at #Epigenetics in #Development and Disease #KSEpigenetics25 keysym.us/KSEpigenetics25 #RNA #GeneReg #RNAsky #GeneRegulation

hi, are you, or do you know a musician in san diego? i need to borrow guitar amp and PA in couple weeks. please RT and help connect me to gear!🎸 @benoitbruneau.bsky.social @wbderry.bsky.social @thelovelylab.bsky.social @chrmosimann.bsky.social @zineeditor.bsky.social @nstop.com @lostsoundtapes.com

. Haiku for 2025 Every day it's just What in the actual fuck Please please make it stop #haiku

Polls close shortly in Germany. What a good election outcome for Europe would look like: - stable two-part government formed swiftly - AfD underperforming (sub-20%) - clear 2/3 majority (420+ seats) for debt-brake reform - parties pivoting fast from campaign to wider realities

Incredibly timely and informative review article @cp-cell.bsky.social by @jstingele.bsky.social and team on #RNA Damage www.cell.com/cell/fulltex...

KA: Asking does Integrator loss allow for generation of double stranded RNA - answer yes - accumulation of dsRNA is seen - PKR also noted to localise close to the dsRNA #LorneGenome25

Up next Karen Adelman discussing Disruption of the Integrator complex triggers the Integrated Stress Response through formation of double-stranded RNA #LorneGenome25

@maxplanck.de President @patrick-cramer.bsky.social is on it already. www.spiegel.de/wissenschaft...

@wazimismail.bsky.social has been selected to present at the @keystonesymposia.bsky.social ! If you are around don’t miss his presentation. #LabFunEpi

We are recruiting! Center for Gene Expression has 2 or more open positions for PhDs @ucph.bsky.social. Come join our team to work on RNAPII and transcriptional regulation (gregersenlab.com). It's a wonderful city and amazing research environment. Deadline March 6. jobportal.ku.dk/phd/?show=16...

Hello everyone on Bluesky! 🧪 We are EMBO, the organization of more than 2,100 leading researchers that promotes excellence in #lifesciences in Europe and beyond. Read more: www.embo.org/about-embo/m...

Postdoc positions on nuclear RNA biology available in the Heick Jensen lab. Come join us in tiny Denmark. Interested? - then follow this link: mbg.au.dk/aktuelt/ledi...

Reupping this in case it applies to anyone. Please signal boost.

We did a thing... We purified native transcriptional complexes from Drosophila embryos, obtaining +/- stalk Pol II elongation complexes, native nucleosomes, as well as a nucleosome elongation complex. For more details please check out: doi.org/10.1101/2025...

Hello Everyone! 👋 Nucleic Acids Research is excited to be on Bluesky! Please follow us for the latest #Research, #Breakthrough articles, journal issues and more. Also, please consider adding us to your starter packs!

When you look for secreted biomarkers and only find BSA

#RNAsky #RNA Beautiful venue - stellar speakers: organized by Karen Adelman @hms-bcmp.bsky.social and Kristian Helin @helink.bsky.social !! Register soon to get the early discount. !!Bonus!! this will be paired with Chromatin architecture meeting organized by @voslab.org, Luca Georgetti & John Lis

February 19 is your last chance to get a $200 discount on the joint Epigenetics/Chromatin Architecture and Transcription Regulation meeting. #KSEpigenetics25 #KSChromatin25 #epigenetics #humandevelopment #developmentalbiology #​​chromatin #chromatinarchitecture youtu.be/zwUnqEdZduk

Join BCMP Faculty, Karen Adelman, at the Epigenetics in Development and Disease Meeting in Banff March 30-April 2.

A new handle for understanding depression and the gut-brain connection? BCMP faculty Jon Clardy and colleagues report bacterial metabolism of environmental contaminant DEA drives cytokine IL-6 release. #microbiome #chemisky @pubs.acs.org

Manifesting being invited to 30 year anniversary of the Matrix events. Putting that out into the universe now, so I'm ready for it in 2029.

All the #NatureReviews journals and Nature Protocols are now on Bluesky, lots of Editors added to the starter pack too if you want to follow us 🧪 go.bsky.app/KcxvQLp

2025 Fragile Nucleosome talks kick off this Wednesday with two great speakers! We'll hear about everything from tardigrades and cryo-EM of nucleosome bound factors to SWI/SNF, LTRs, and ovarian tumors. You won't want to miss this one, register here! us06web.zoom.us/webinar/regi...

While I realize this is not relevant to many of the present day discussions, the remarkable similarity of organisms at the biochemical, genetic, cellular, and physiological levels is not understood by many people. 1/n

it would be mean of me to not show you this picture taken this morning #colorado #winter. have a peaceful sunday y'all... deep breaths.