Erdinc Sezgin
@sciezgin.bsky.social
📤 780
📥 739
📝 20
Scientist Immunology, Membranes, Lipids, Microscopes, Open Science
reposted by
Erdinc Sezgin
@KayTrue (Sarah L. Keller)
3 days ago
Congratulations to
@sciezgin.bsky.social
for being honored with the 2026 Early Independent Career award from the
@biophysicalsoc.bsky.social
!
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Erdinc Sezgin
Coskun Lipid Cellar @ ZML Dresden
2 months ago
Ups we did it again! Please mark your calender. EMBO Workshop “Lipid Code to Life”, taking place September 7–11, 2026, in Dresden, organized by Maria Fedorova,
@lipid.bsky.social
, Valerie O'Donnell,
@holthuislab.bsky.social
and
@molcellbiophys-lab.bsky.social
🥳 Retweets = lipidlove
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Erdinc Sezgin
Anna Duncan
4 months ago
Registration now open for the '3rd Annual Danish Workshop on Advanced Molecular Simulation' Join us in beautiful Aarhus for a 2-day workshop on biomolecular simulations! 9-10 December 2025 Link for registration:
aias.au.dk/events/show/...
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Erdinc Sezgin
Jeremy Baskin
4 months ago
#ACSChemBio
and
#Biochemistry
invite submissions to a special issue on Lipids and Lipidation guest edited by
@chembiobryan.bsky.social
and me! Find details in the
#CallforPapers
and submit your exciting findings to one of these journals by May 31, 2026.
axial.acs.org/chemical-bio...
#lipidtime
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Call for Papers: Lipids and Lipidation | ACS Publications Chemistry Blog
This Special Issue in _ACS Chemical Biology_ will highlight the latest advancements and perspectives in the chemical biology of lipids and lipidation. Submit your manuscript by May 31, 2026.
https://axial.acs.org/chemical-biology/call-for-papers-lipids-and-lipidation
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Lipids are back :) congrats team!
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5 months ago
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Erdinc Sezgin
André Nadler
5 months ago
Lipid imaging on the cover of
@nature.com
! Great times for lipid cell biology indeed. And a fantastic recognition of all the hard work by the team, especially Juan M. Iglesias-Artola and Kristin Böhlig (who made the cover). Link to article:
www.nature.com/articles/s41...
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The last edition in Lisbon was incredible! I’m sure this one will be nothing short of that!
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5 months ago
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Erdinc Sezgin
GBM (Gesellschaft für Biochemie und Molekularbiologie)
5 months ago
Registration open: 77. Mosbacher Kolloquium "More than lipidic barriers - New horizons in membrane biology" from March 25-28, 2026
lnkd.in/dgsW4c3
Scientific Organizers: Britta Brügger, Robert Ernst, André Nadler, Christian Ungermann Early registration & poster abstracts until January 31, 2026
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Rita Strack
5 months ago
I hope this Nobel Prize gets people talking meaningfully about our amazing immune systems and the importance of basic research to human health (and funding basic research). I am also glad young women get to see that women can not only work at this level, but that those who do can get recognized.
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Cell Physics community is missing Jochen Guck deeply.. He was a very kind and generous person, one of the most creative minds, and always ready to help everyone in the field.. He inspired many of us.. He will always be missed..
5 months ago
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Erdinc Sezgin
Waggoner Lab
5 months ago
Get your Zoster vaccine!
@naturemedicine.bsky.social
A consistent relationship of VZV reactivation with dementia in 100M US adults after controlling for nearly 400 measured characteristics, with zoster vaccines reducing risk of dementia in dose-dependent manner
www.nature.com/articles/s41...
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Erdinc Sezgin
Dimova Lab
5 months ago
Great talk from
@sciezgin.bsky.social
(aka komsu) at the
#BiomembraneDays25
on correlating biophysical properties like packing and hydration to biomatkers for disease
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Erdinc Sezgin
Ewerslab
5 months ago
@sciezgin.bsky.social
will kick off the second morning session!
#BiomembraneDays2025
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Erdinc Sezgin
Gene Chong
5 months ago
Are the lipids associated with static protein structures there as long-lived ligands or an effect of preferential solvation? This computational-experimental framework shows the way!
#lipidtime
#compchem
www.nature.com/articles/s41...
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Molecular basis for the regulation of membrane proteins through preferential lipid solvation - Nature Chemical Biology
Static protein structures can capture the association of lipids, but it is unclear whether the association is due to lipids acting as long-lived ligands or the solvation of preferred lipids around the protein. A computational-experimental framework has now shown that for the protein CLC-ec1, it is the change in lipid solvation energies that drives dimerization, with preferred lipids around the protein modulating this driving force.
https://www.nature.com/articles/s41589-025-02032-w?utm_source=bluesky&utm_medium=social&utm_campaign=nchembio
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So flattering! Thanks
@biophysicalsoc.bsky.social
for this deeply meaningful award! All credit goes to my lab members and collaborators.
@scilifelab.se
@ki.se
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5 months ago
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Pretty sure everyone has seen it already, but if you are also late like me, here is an excellent lipidtime paper by
@nadlerlab.bsky.social
and Co. One step closer to understanding the spatiotemporal lipid diversity in cells!
add a skeleton here at some point
6 months ago
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Erdinc Sezgin
André Nadler
6 months ago
Out today in
@nature.com
: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
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Previous preprint is now published in RSC Chemical Biology. If you are interested in plasma membrane labeling, see the paper! 👇
pubs.rsc.org/en/content/a...
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6 months ago
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Erdinc Sezgin
Filipa Simões
8 months ago
🧪 Job alert 🔊 we are hiring a Research Assistant - join the Simões Group at DPAG-IDRM
@ox.ac.uk
supporting
#cardiovascular
development and regeneration research, working with
#zebrafish
and
#human
stem cell systems:
my.corehr.com/pls/uoxrecru...
@oxforddpag.bsky.social
@idrm.ox.ac.uk
(1/4)
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Job Details
https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10&p_internal_external=E&p_display_in_irish=N&p_process_type=&p_applicant_no=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y&p_recruitment_id=180719
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Erdinc Sezgin
Journal of Cell Science
8 months ago
Journal of Cell Science is published by a not-for-profit charitable organisation (
@biologists.bsky.social
) that exists to benefit science, not shareholders. We provide Travelling Fellowships, Training Grants, support for ECRs and more. For details, visit:
journals.biologists.com/jcs/pages/re...
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Erdinc Sezgin
James Saenz
8 months ago
@leventallab.bsky.social
kicking off the
@biophysicalsoc.bsky.social
conference on membrane complexity…looking forward to an awesome week exploring membrane complexity!
#BPSmembranecomplexity
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Erdinc Sezgin
Levental Lab
8 months ago
Amazing first session at
#BPSmembranecomplexity
!! So much fantastic new science in studies of complex membranes. Big thx to our sponsors for making this possible!!
@biophysicalsoc.bsky.social
@pubs.acs.org
@embo.org
@febspress.bsky.social
@biologists.bsky.social
@lipotype.bsky.social
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New PI alert! It was the last week for Jan
@jan-schlegel.bsky.social
in the lab! Sad to see him leave, but very proud that he is on his way to realising his dreams! His lab will work on fundamentals of host-pathogen interactions. Fig1: his first day and Fig2: his last day at
@scilifelab.se
@ki.se
8 months ago
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Erdinc Sezgin
James Saenz
8 months ago
Hot off the press, our latest review of RNA-lipid interactions -> The secret life of RNA and lipids: "There is no life without RNA or lipids. But could there be life with only RNA and lipids?"
@tcjea.bsky.social
@bcube-tud.bsky.social
be-tud.bsky.social
www.tandfonline.com/doi/full/10....
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The secret life of RNA and lipids
There is no life without RNA or lipids. But could there be life with only RNA and lipids? The discovery that RNA can catalyse reactions in addition to encoding information opened new directions for...
https://www.tandfonline.com/doi/full/10.1080/15476286.2025.2526903#abstract
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Erdinc Sezgin
Guillaume Jacquemet
8 months ago
- A postdoc to work on cancer extravasation (4-year project). - A postdoc help in completing Filopodia-related lab projects (2-year). - Multiple Marie Curie postdoc positions that will open in the fall. - We will open a 5-year position to cover my teaching (70% research and 30% teaching).
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New paper alert: Focusing nanoscale particles in microchannels..
onlinelibrary.wiley.com/doi/full/10....
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Sheathless Elasto‐Inertial Focusing of Sub‐25 Nm Particles in Straight Microchannels
High-aspect-ratio microchannels with elasto-inertial microfluidics effectively focus sub-micron particles without a sheath flow. This enables precise manipulation of biological nanoparticles like lip...
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202503369
8 months ago
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Erdinc Sezgin
André Nadler
8 months ago
Here's a job at my institute that just opened up: Max Planck Director in Biological AI. This is an amazing opportunity -
www.mpi-cbg.de/news-outreac...
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Open Call: Max Planck Director in Biological Artificial Intelligence
Expressions of interest or nominations to lead research in the field of Biological Artificial Intelligence at MPI-CBG.
https://www.mpi-cbg.de/news-outreach/news-media/article/novel-research-in-biological-artificial-intelligence
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Erdinc Sezgin
Karolinska Institutet
8 months ago
Save the date! On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility
news.ki.se/ki-to-recruit-junior-researchers-with-a-focus-on-excellence
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KI to recruit junior researchers with a focus on excellence
On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility. As one of Europe’s leading medical universities, KI offe...
https://news.ki.se/ki-to-recruit-junior-researchers-with-a-focus-on-excellence
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Amazing news Andrey!! Looking forward to the outcome of this project !!!
add a skeleton here at some point
8 months ago
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Erdinc Sezgin
COMBINE MARV Project
9 months ago
💡Learn more about Erdinc’s role in COMBINE by watching the video or visit our website 🔗
combine-marv.eu/team/ki
#combineMARV
#MarburgVirus
#PandemicPreparedness
#Biophysics
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Erdinc Sezgin
Matthieu Chavent
9 months ago
Our joint paper with Wonpil Im lab is now available as a preprint: "Dynamic Architecture of Mycobacterial Outer Membranes Revealed by All-Atom Simulations"
www.biorxiv.org/content/10.1...
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Erdinc Sezgin
Journal of Cell Science
9 months ago
After the success of our 2023 Imaging Cell Dynamics conference, we’ll be hosting a second
#JCSImaging
meeting in 2026, organised by
@franbottanelli.bsky.social
,
@guijacquemet.bsky.social
,
@drmichaelway.bsky.social
& Giulia Zanetti. To register your interest:
www.biologists.com/meetings/jcs...
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Erdinc Sezgin
Emmanuel Margeat
9 months ago
- Melike Lakadamyali
@melikel.bsky.social
- Emmanuel Margeat
@emmanuelmargeat.bsky.social
- Ons M’Saad - Ivana Nikic-Spiegel - Erdinc Sezgin
@sciezgin.bsky.social
- Alison Tebo (TBC)
@agtebo.bsky.social
Apply here before October 31th 2025.
fluorescenceleshouches.wordpress.com
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Erdinc Sezgin
James Saenz
9 months ago
Kicking off a week of sphingolipid biology
@slbiology.bsky.social
with the Dresden
#lipidtime
crowd 🤩🔥
@fedorovalab.bsky.social
and
@sciezgin.bsky.social
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Erdinc Sezgin
Daniel Bojar
10 months ago
A few GlycoDraw-related highlights of the upcoming glycowork v1.6 update (dropping in a few weeks): - our very own rendering engine (GlycoDraw for the masses, thanks to glycorender!); - SNFG-gradients; - automated Alt text; - reverse-highlighting; - even more support for highly complex sequences
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New paper out! Would you like to fluorescently label the plasma membrane in live, fixed or permeabilized cells? I tested different lipid structures and labelling approaches to decide what makes a good membrane labelling probe for such imaging experiments!
www.biorxiv.org/content/10.1...
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Plasma membrane labelling efficiency, internalization and partitioning of functionalized fluorescent lipids as a function of lipid structure
Labeling the plasma membrane for advanced imaging remains a significant challenge. For time-lapse live cell imaging, probe internalization and photobleaching are major limitations affecting most membr...
https://www.biorxiv.org/content/10.1101/2025.05.07.652622v1
10 months ago
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Erdinc Sezgin
Marcin Czerwinski
10 months ago
Specificity in glycosylation! Have you ever wondered why some glycosyltransferases recognize glycoproteins, some glycolipids, and some both? Together with
@kmikolajczyk.bsky.social
and
@rkaczmarekdr.bsky.social
, we try to answer that complicated question.
#glycotime
tinyurl.com/5b6kxhp3
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Erdinc Sezgin
André Nadler
10 months ago
Why are biological membranes asymmetric, with different lipids in the two bilayer leaflets? Discovered in the 70s, lipid asymmetry is linked to many cellular processes, but why the cell needs it is largely unclear.
@pavelbarahtjan.bsky.social
addresses this question:
www.biorxiv.org/content/10.1...
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Erdinc Sezgin
Gonçalo Castelo-Branco
10 months ago
Join us at the Nobel Symposium Multiple Sclerosis: Past, Present and Future Treatment June 5th, 2025 | Jacob Berzelius lecture hall
@ki.se
| Stockholm, Sweden free registration at:
jirango.com/cview/web/f0...
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Erdinc Sezgin
Gene Chong
11 months ago
It’s
#lipidtime
. The authors capture oscillations in the abundance of different phospholipid species during the yeast cell cycle, suggesting regulation and interplay of phospholipid synthesis, membrane fluidity, and metabolic efficiency during cell division
www.nature.com/articles/s41...
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Temporal oscillation of phospholipids promotes metabolic efficiency - Nature Chemical Biology
Temporal oscillations in the abundance of different phospholipid species during the yeast cell cycle are reported, suggesting regulation and interplay of phospholipid synthesis, membrane fluidity and ...
https://www.nature.com/articles/s41589-025-01885-5?utm_source=bluesky&utm_medium=social&utm_campaign=nchembio
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Erdinc Sezgin
Stella Hurtley
11 months ago
www.science.org/doi/10.1126/...
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Erdinc Sezgin
Jeremy Baskin
11 months ago
Groundbreaking study in Cell from
@leventallab.bsky.social
: phospholipid asymmetry is a defining feature of the plasma membrane and cholesterol fills the holes — major implications for how this membrane works. A
#lipidtime
must-read!
www.cell.com/cell/abstrac...
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Cell membranes sustain phospholipid imbalance via cholesterol asymmetry
This work challenges a major assumption in cell biology by showing that lipid bilayers can have drastically different phospholipid abundances between their two leaflets. This lipid abundance asymmetry...
https://www.cell.com/cell/abstract/S0092-8674(25)00270-3
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Erdinc Sezgin
Filipa Simões
11 months ago
Come and work with us OOH
@oxforddpag.bsky.social
: ❤️ organoids to study 1) failing hearts and 2) metabolite signalling, with
@novonordisk.bsky.social
and wonderful colleagues 1) Andrew Lewis & Chris Toepfer
@rdmoxford.bsky.social
; 2) Yimon Aye
@oxfordchemistry.bsky.social
. Reach out if interested!
add a skeleton here at some point
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New PI born 💥 Jan Schlegel
@jan-schlegel.bsky.social
is soon starting his lab in Helmholtz Centre for Infection Research in Germany :) So proud to see him flying to new horizons with his limitless curiosity! You want to be part of his journey? He is looking for a PhD/Postdoc 👇
lnkd.in/er5NYXGv
11 months ago
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Erdinc Sezgin
Dimova Lab
11 months ago
1/8 Exciting new work with Agu
@mangiarotti.bsky.social
@mpici.bsky.social
! 🚀 Our latest study explores how lipid packing and cholesterol regulate the interaction of biomolecular condensates with membranes. It turns out, it’s not just about membrane phase. Packing is the key! 🧵👇
rdcu.be/eelLq
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Lipid packing and cholesterol content regulate membrane wetting and remodeling by biomolecular condensates
Nature Communications - Membrane lipid packing, influenced by cholesterol, lipid chain length, and saturation, regulates the affinity of biomolecular condensates, enhancing their interactions with...
https://rdcu.be/eelLq
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Erdinc Sezgin
Jeremy Baskin
12 months ago
🚨New preprint: There's this overlooked phospholipid with 3 acyl tails called NAPE that is made during ischemia. We identified its interactome & found it regulates lactate flux, suggesting metabolic functions in response to hypoxia. Congrats to Dylan Chiu!
doi.org/10.26434/che...
#lipidtime
#chembio
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Erdinc Sezgin
Mattia Morandi
12 months ago
Proud to announce our latest work on malaria-derived EVs is live! Couldn’t have done it without Daniel Alfandari and the lab of Neta Regev-Rudzki.
pubs.acs.org/doi/full/10....
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Host Immune Cell Membrane Deformability Governs the Uptake Route of Malaria-Derived Extracellular Vesicles
The malaria parasite, Plasmodium falciparum, secretes extracellular vesicles (EVs) to facilitate its growth and to communicate with the external microenvironment, primarily targeting the host’s immune...
https://pubs.acs.org/doi/full/10.1021/acsnano.4c07503
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Erdinc Sezgin
Ivan Maslov
12 months ago
How is one dye
#NileRed
(NR) the sensor of both polarity and microviscosity? Sarkar et al. correlate spectral shifts and fluorophore orientations of single molecules of NR in Lo/Ld supported lipid bilayers PhysChemB:
doi.org/10.1021/acs.jpcb.4c07578
🔓 bioRxiv:
doi.org/10.1101/2024.06.21.600028
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Spectrally Resolved Single-Molecule Orientation Imaging Reveals a Direct Correspondence between the Polarity and Microviscosity Experienced by Nile Red in Supported Lipid Bilayer Membranes
Molecular-level interactions among lipids, cholesterol, and water dictate the nanoscale membrane organization of lipid bilayers into liquid-ordered (Lo) and liquid-disordered (Ld) phases, characterize...
https://doi.org/10.1021/acs.jpcb.4c07578
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reposted by
Erdinc Sezgin
Dimova Lab
about 1 year ago
📢 SAVE THE DATE: Sept 29 - Oct 1, 2025 and come to Berlin to the BIOMEMBRANE DAYS Excellent line of speakers and slots for contributed talks. Registration will open in Spring.
biomembrane-days-2025.mpikg.mpg.de
Organized by
[email protected]
Thomas Weikl and myself
@mpici.bsky.social
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New paper out 🎇 It has been 13 years since
@owenlabuob.bsky.social
and co. published a stellar protocol on how to measure membrane order with smart probes! Since then, there has been new dyes, imaging modes and biology! We wrote a protocol for Nature Protocols:
www.nature.com/articles/s41...
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Measuring plasma membrane fluidity using confocal microscopy - Nature Protocols
Membrane fluidity is a crucial feature in understanding cellular physiology. This protocol describes a robust pipeline for measuring plasma membrane fluidity using confocal imaging and new environment...
https://www.nature.com/articles/s41596-024-01122-8
about 1 year ago
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