Huntington's disease has been successfully treated for the first time, doctors tell BBC

Copy our protocols! 📝 Find many of our lab protocols and techniques on @protocolsio.bsky.social at www.protocols.io/search?q=%22... 🎥 Go deeper with recorded video tutorials of some of our most requested methods: alleninstitute.org/education/sc... #OpenScienceWeek

Great to see our review on microbiome, exposome and cognitive development out in @annualreviews.bsky.social. @apcmicrobiomeirel.bsky.social @uccresearch.bsky.social #MicrobiomeSky #Gut-Brain

Incredible resource and a big step forward in modelling neurodevelopmental disorders 👇🏻 #organoids #neurodevelopment

🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f Here we tackle a long-standing chicken-or-egg 🐣🥚question in #autism and developmental neuroscience ➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of #autism? Check out what we found! 🧵1/n

Our lncRNA-in-brain review is out in @natrevneuro.nature.com ✨ The emerging roles of long noncoding RNAs in the brain We discuss 🧬 lncRNA roles in brain development, synaptic function, learning, & behavior 💡 Therapeutic potential and future directions. @unswrna.bsky.social @unswbabs.bsky.social

OneNeuro's August #FotoFriday #FluorescenceFriday contest winner is "Cellular Subtype Composition of an Amphetamine-activated Ensemble in mPFC," by Suhaas Adiraju from @martinowk.bsky.social at the @lieberinstitute.bsky.social View the complete gallery here: www.oneneurojhu.org/art/

Honoured to have shared our recent findings on 16p11.2 CNV-associated syndromes at the Neurofront meeting at University of Bari. Inspiring talks covering precision medicine, biomarkers discovery, stem cells, advanced imaging and glial cells. Looking forward to the next meeting!

I am a co-supervisor on one of these #PhD projects, led by @asamioguroando.bsky.social Find the details here: gw4biomed.ac.uk/neuronal-clu...

Are you interested in understanding how cells communicate during development? We are now accepting applications for a Senior Scientist in my group at St. Jude Children's Research Hospital! Please ✅ out the link below. Reposts appreciated! 🧪 👩‍🔬 🔬 stjude.wd1.myworkdayjobs.com/stjude/job/M...

Ever wanted to do a CRISPR screen directly in the mammalian brain? While perturbing thousands of genes in parallel? All while targeting specific cell types? Check out our latest paper describing CrAAVe-seq, a powerful new functional genomics tool for massively parallel neuroscience research

Could a vaccine help prevent dementia? Data suggests the shingles vaccine is linked to a lower risk of developing dementia, adding to evidence that viral infections could influence brain health. 🎙️@tspiresjones.bsky.social breaks down the findings on BBC Radio 4's Inside Health ⬇️

A new #ScienceReview looks at a different approach to drug discovery that may enable drugging of unconventional targets through stabilization of macromolecular complexes with molecules known as “LOCKTACs.” Learn more: https://scim.ag/4lC2aCM

Important initiative 👇

Have a research project that requires analysing microscopy data? Master the skills you need in our upcoming ‘Introduction to image analysis’ technical training course. 📅 27-28 October 📍 The Francis Crick Institute For more info and to apply 👇 www.crick.ac.uk/whats-on/int...

"For half an hour, I vented everything I had been holding in for months … my supervisor … then calmly offered a line I’ll never forget: 'You are here to learn to ride a bicycle, not to invent a bicycle.' That one sentence landed softly, but it cracked something open." https://scim.ag/4lt1Ru0

🧠 What triggers brain aging? A new Science (@science.org) study by SNS, Stanford & Leibniz Institute points to stalled protein synthesis as a key factor behind cognitive decline. Understanding this process may open new paths for medical intervention. Read more: www.science.org/doi/10.1126/...

Time pressure gets in the way of ideas. Developing ‘creative oases’ and small grants for risky ideas can encourage innovative thinking in science go.nature.com/459cPQz

A very good read if you want to learn everything there is to know about dopamine. Take a look at chapter 4! www.sciencedirect.com/handbook/han...

I’m incredibly stoked to announce our latest preprint led by Thijs Verhoog, where we show that human cortical neurons mature hundreds of times slower than mouse neurons, only reaching functional maturity well into the third decade of life. www.biorxiv.org/content/10.1...

Just dropped in @natcomms.nature.com: we show that re-engaging a thalamic–ventral tegmental circuit with deep brain stimulation can reignite consciousness in patients with severe brain injury. Work led by Aaron Warren, with @andreashorn.org @foxmdphd.bsky.social @ others! tinyurl.com/4kz8j89b

New research has established the molecular mechanism that drives interneurons in the cerebral cortex to mature. The work provides clarity how cortical circuits develop and on the mechanisms behind neurodevelopmental disorders. Click to learn more👇 bit.ly/3THw7Gb

Hot off the press! 🔥 Review in the Journal of Neurochemistry exploring neural stem cell-derived extracellular vesicles (NSC-EVs) as a promising therapy for neurodegenerative diseases! We discuss how they fight inflammation & boost repair in the brain. onlinelibrary.wiley.com/doi/10.1111/...

The human proteome and organ age clocks across the lifespan, a tour de force report @cellpress.bsky.social www.cell.com/cell/abstrac...

For the first time, researchers from @mpi-psychiatry.bsky.social have shown how environmental stressors alter neuronal balance before birth. Explore the research: maxplanckneuroscience.org/stress-alter...

Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. 🔗 All positions: ki.se/en/about-ki/...

Microglia don’t act the same around the clock! Their transcriptional/proteomic/functional programs shift across sleep/wake phases - yet most studies ignore time-of-day. This perspective calls for a circadian rethink in neuroimmunology! pubmed.ncbi.nlm.nih.gov/40618264/

We’re hiring! Join us @unige_en as a Full/Associate Prof. in Neuroscience (Chair of Excellence). Focus: development, molecular & cellular evolution of brain circuits. Great team, top science, Geneva 🇨🇭 🧠 Apply by Aug 15, 2025 jobs.unige.ch/www/wd_porta...

Sex chromosome aneuploidies (varying X/Y-chrom dosage) can increase risk for psychopathology, but do these risks vary with age ? This matters for both clinical and mechanistic understanding. A fab recent trainee - Melissa Roybal - asked these questions in a new paper. This is what she found ... ⬇️

Exciting Senior Scientist 👩‍🔬 👨‍🔬 role available in my research group 🧠 🦠 - Closing date Tuesday 5th August 2025. Please Share @apcmicrobiomeirel.bsky.social @anatneuroucc.bsky.social Full details here my.corehr.com/pls/uccrecru...

Exciting Research Professorship Position in Stem Cell and Developmental Biology at the University of Leuven. Amazing research ecosystem, great colleagues, high quality of life, tenure track. For those interested in joining us, please see below: www.kuleuven.be/personeel/jo...

An organ-chip model of sporadic ALS using iPSC-derived spinal cord motor neurons and an integrated blood-brain-like barrier

Identificata riduzione della connettività cerebrale associata alla pubertà nella sindrome da delezione 22q11.2. Lo studio, su #ScienceAdvances, è stato guidato dal team di @gozziale.bsky.social, F.Alvino, S.Gini, con @uclacollege.bsky.social e @unipisa.bsky.social opentalk.iit.it/leffetto-del...

Alert! ... for the child development world! @fluxsociety.bsky.social @fitngin.bsky.social ‪ The Healthy Brain and Child Development (HBCD) Study has released its first data wave - it’s massive. Check here: docs.hbcdstudy.org and here: nbdc-datahub.org Here’s why it matters 🧠🍼

Neurons often receive mitochondria from other cells, supporting cancer cell spread https://go.nature.com/3ZLBhnV

Happy to share our review at Cell Stem Cell as part of their Hallmarks series. As always, a pleasure to work with friends and colleagues Anne Brunet (@brunetlab.bsky.social) and Peggy Goodell(@goodell-lab.bsky.social). Hallmarks of stem cell aging: Cell Stem Cell www.cell.com/cell-stem-ce...

SCN2A is a top risk gene for autism. But how does losing one copy of it affect dendritic function during flexible decision-making? 🧬🐭🧠🧪 Our study in preprint @biorxivpreprint: www.biorxiv.org/content/10.1... Supported by a @simonsfoundation.org SFARI Pilot Award 🙌 #SCN2A #cureSCN2A

Wyss researchers have devised a synthetic biology approach to differentiate a vital type of immune cell in the brain, microglia, in the dish, faster and more efficiently than ever before. This work was published today in @natcomms.nature.com.

Congrats @akanksha-jain.bsky.social @graycamplab.bsky.social & Treutlein lab on publishing this @nature.com study on early brain organoid development, with insights into processes underlying brain regionalization 🧪🧠🧬🧫 www.nature.com/articles/s41...

Hey all, faculty position here at EMBl Rome closing in 10 days! We looking for people at the intersection of neuroscience and epigenetics (broadly interpreted, totally OK if stronger on one side or another) 1/x embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Meet MapMyCells! This tool saves neuroscientists precious time by comparing their data to massive, high-quality reference datasets, including our whole mouse brain multi-omics atlas and the Seattle Alzheimer’s Disease Brain Cell Atlas. 🧠📈 portal.brain-map.org/atlases-and-... #studyBRAIN

I feel seen as an ECR dependant on grant funding for continued employment. Some excellent points raised in this blog, and interesting discussion about how research grants are funded. Very much worth a read.

We are happy to seek 3 post-docs across Edinburgh Napier, Glasgow & UCL in an exciting project to investigate mechanisms linking glial ageing/longevity & neurodegeneration (MRC-funded). Info attached @nathanwoodling.bsky.social @ukdri.ac.uk @uclqsion.bsky.social @uclbrainscience.bsky.social

🧠 New study led by our talented graduate student Courtney Benoit, uncovers how the autism-linked gene POU3F2 supports brain development by promoting neural stem cell growth via Wnt signaling and key targets like ADNP and SOX13. Check it out here in Brain: academic.oup.com/brain/articl...

💊🧠 Game-changer: Common drugs linked to lower dementia risk! Cambridge study of 130M people shows: • Antibiotics & antivirals reduce risk • Anti-inflammatories protective • Vaccines offer benefits Could existing medications be repurposed for prevention? zurl.co/uGKr0 #Dementia #Research

Nice ideas from Prof. Sheena Josselyn 💃🏻 Univ. of Toronto: Sit down and think about it … www.thetransmitter.org/craft-and-ca...

Autism linked with a fourfold increased risk of Parkinson’s disease, according to a study of more than 2 million people. By Charles Q. Choi www.thetransmitter.org/spectrum/lar...

Aberrant cerebrovascular reactivity presents as an early biomarker of psychosis susceptibility in patients with 22q11.2DS https://www.biorxiv.org/content/10.1101/2025.06.02.657392v1

🎓 Calling all Master, PhD students & early-career postdocs in Europe! Applications for FENS/IBRO-PERC Exchange Fellowships are OPEN 🌍 Boost your research in a host lab & connect with local neuroscientists. Apply by 15 Oct 👉 buff.ly/Qoe2Dd0 #grant #neuroscience #IBROinEurope @fens.org

Researchers led by Prof David Klenerman have developed ultra-sensitive tests that can detect blood-based disease markers - potential quick, affordable blood tests that could diagnose neurodegenerative conditions earlier Read more 👉 www.ukdri.ac.uk/news-and-eve...