Mark Mahan, MD, recently performed the first microrobotic surgery with our new Symani system! We’re committed to investing in technological evolution and are so excited to be using this incredible system.

Classic publication using Lead-DBS: In this article by Mei et al., the authors tested functional zonal image-reconstruction-guided programming for STN-DBS in Parkinson’s patients and found it reduced... Check out the paper here 👇👇 https://www.frontiersin.org/articles/10.3389/fneur.2022.916658/full

Classic publication using Lead-DBS: In this article by Han et al., the authors systematically reviewed DBS for extreme behaviors in ASD (nine patients) and used connectomic mapping of electrode locati... Check out the paper here 👇👇 https://thejns.org/view/journals/j-neurosurg/137/3/article-p699.xml

New publication using Lead-DBS: In this article by Anonymous et al., the authors report on Las Vegas Sands Corp.'s lawsuit against unknown registrants of multiple domain names (e.g., www.wn0000.com, www.wn1111.com, www.4456888.... Check out the paper here 👇👇 https://doi.org/10.1089/glre.2016.201011

Someone has 3D printed a brain model - complete with activation lights! You can actually upload fMRI data and visualize the activations in real time right there on your desk! youtu.be/yNct2cJM9BQ?... #fmri #neuroscience

Classic publication using Lead-DBS: In this article by Singh et al., electrical stimulation mapping of the anterior insula during stereo-EEG induced time-locked pathological crying and profound sadness in... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S2589986420300691

Happy to share that our paper on objective quality assessment for "precision" fMRI is now out in @cp-neuron.bsky.social A recap of what it does, what's new since the preprint, and code you can run on your own data. cell.com/neuron/fullt...

These models were not built to explain the brain. But treating them as model organisms that we can perturb and evolve will move us closer to truly understanding the brain’s mechanics, writes @mtoneva.bsky.social. #neuroskyence www.thetransmitter.org/artificial-i...

Two of the most important biomedical breakthroughs came from science of the Gila lizard venom (GLP-1s) and yogurt (CRISPR genome editing). "The system that turned that lizard into a medicine is now being dismantled." gift link nytimes.com/2026/06/20/o...

New publication using Lead-DBS: In this article by Bernardi et al., the authors describe a 15-year-old female with a novel DNAJC6-associated juvenile parkinsonism whose disabling, medication-refractory tremor was markedly and sustaina... Check out the paper here 👇👇 https://doi.org/10.5334/tohm.1187

Classic publication using Lead-DBS: In this article by Loeffler et al., the authors tested deep brain stimulation of the ventralis intermedius nucleus and adjacent subthalamic proj... Check out the paper here 👇👇 https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.1048530/full

Classic publication using Lead-DBS: In this article by Scerrati et al., the authors report on three patients with dystonic midline tremor treated with deep brain stimulation targeting the thalamic Ventral‑Oralis com... Check out the paper here 👇👇 https://link.springer.com/10.1007/s00415-024-12619-3

Open Mind, the free OA competitor to Cognition (El$evier) founded by Richard Aslin, has nearly caught up to it impact-factor-wise Submit your best work! It's a great journal with fast and constructive review, a great ed board, and lots of cool work Open Mind is the future of cogsci journals!

Classic publication using Lead-DBS: In this article by Horn et al., the authors introduce and validate a method to map neurosurgical AC/PC DBS electrode coordinates into MNI space without patient MRIs, tes... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S1053811917301088

Finally finished @philipcball.bsky.social's wonderful "How Life Works"! When I hit the part on the 2nd Law felt compelled to share my comic on Entropy from a few years back, bits of which I'm expanding on in the new work (& one reason I read this brilliant book!) spinweaveandcut.com/sketching-en...

I love AI because I don’t like life or doing things

Of course missing from all of this is any mention of dozens of reports on a likely zoonotic origin - no link to the WHO report, HSM market origins papers, epidemiology, sequencing data etc. As a special gift to the ODNI, here's a TOP SECRET link to all of these: www.pnas.org/doi/10.1073/...

What an incredible which hunt. Crazy how a government can dump such a report and blame an individual in isolated fashion, do so without any evidence but with an obvious aim to discredit a person (rather than an institution). If your fascism warning lights are not yet on, I dont know what's needed.

I leave you all with my personal favorite page from this illuminating dump: It's the key findings of 2016 IC analysis of H5N1 research that's been debated & digested ad infinitum in already published docs. This level of transparency really sums up the Big Reveal that the ODNI has finally given us!

Classic publication using Lead-DBS: In this article by Jorge et al., the authors tested the relationship between STN DBS contact location and voice in Parkinson disease and found that anterior sensorimotor STN stimulatio... Check out the paper here 👇👇 https://journals.lww.com/10.1093/neuros/nyaa024

They are going "all in" on zebrafish - do I have that right?

Classic publication using Lead-DBS: In this article by Bardon et al., the authors tested whether subthalamic nucleus active-contact location affects improvement of Parkinson's non-motor symptoms and found no co... Check out the paper here 👇👇 http://biomed.papers.upol.cz/doi/10.5507/bp.2020.034.html

✨ Congratulations to Aperture’s Award Winners honored at #OHBM2026 ✨

Classic publication using Lead-DBS: In this article by Martinez‐Nunez et al., the authors investigated structural and functional connectivity correlates of earlier symptom improvement after bilate... Check out the paper here 👇👇 https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.70152

Classic publication using Lead-DBS: In this article by Warren et al., the authors report a single-center series of centromedian nucleus deep brain stimulation in six children with Le... Check out the paper here 👇👇 https://thejns.org/view/journals/j-neurosurg-case-lessons/10/12/article-CASE25478.xml

So looking forward for this! It’ll be a late night chat for me, but any time is a good time to talk about exciting science 🧠⚡️

Excited to share our work at #OHBM2026! Come by poster 0198 to chat about lesion network mapping, predictive modeling and post-stroke cognitive impairment. 📍 Mon June 15, 14:45–15:45 📍 Tue June 16, 13:30–14:30 @ohbmofficial.bsky.social @ohbmtrainees.bsky.social

Tremor is highly heterogeneous. Our new study in @cp-cellreports.bsky.social shows that rest and action tremor map to different networks within the motor cortex. By refining DBS contact selection, we can engage these circuits to optimize treatment for both. www.cell.com/cell-reports...

We are excited! #OHBM2026 – three @netstim.org papers by Aysu Sahin, Patricia Zvarova & Maike Mustin! 👇👇

Classic publication using Lead-DBS: In this article by Balachandar et al., longitudinal GPi-DBS recordings in ten children showed that status dystonicus is associated with increased periodic pallidal beta-band power a... Check out the paper here 👇👇 https://www.nature.com/articles/s41467-025-64416-9

Classic publication using Lead-DBS: In this article by Bouwens Van Der Vlis et al., the authors analyzed outcomes in eight refractory OCD patients treated with ventral capsule/ventral striatum DBS and used... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S1094715921000891

Classic publication using Lead-DBS: In this review by Piper et al., the authors summarize evidence on epileptic network mechanisms and multimodal mapping—highlighting thalamic propagation points (anterior and... Check out the paper here 👇👇 https://academic.oup.com/brain/article/145/10/3347/6623456

Classic publication using Lead-DBS: In this article by Buijink et al., the authors recorded thalamic local field potentials with a sensing-enabled implanted DBS pulse generator (Medtronic Percept PC) in an... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S2467981X22000129

Oldie but goldie. And the reason this company was always the best computer company in the world. We’re slowly getting there, Steve. youtu.be/welKoeoK6zI?...

Next up is yet another legend of the „new wave“ of adaptive DBS: Eduardo Mourad.

Next up is none less than Simon Little - one of the few people that may claim has fostered a new FDA approval in the field of DBS.

What a great discussion! #optoDBS 2026

The collaboration between @julianneumann.bsky.social and @yttrilab.bsky.social that led to this years keynote seems like a match made in heaven. But in fact, the two met at #optoDBS 2017!

And were live! #optoDBS 2026 is oft to a great start here at Campus Biotech in Geneva. Christian Lüscher kicking off the conference - and since we are broadening the scope a lot: will we call it #optoMOD in the future?

Classic publication using Lead-DBS: In this article by Peisker et al., the authors tested whether nucleus accumbens deep brain stimulation alters delay discounting in nine patients with substance use disorders (DBS on vs after a 24... Check out the paper here 👇👇 http://www.mdpi.com/2076-3425/8/2/21

🎧 Tune in here 🎶 🎧 👇👇 https://stimulatingbrains.org/56-harith-akram-connectomic-dbs-sweetspots-and-building-a-supercomputer/

Classic publication using Lead-DBS: In this article by Zhao et al., they prospectively tested whether preoperative quantitative susceptibility mapping of iron distribution in the substantia nigra, subthalamic nucl... Check out the paper here 👇👇 https://onlinelibrary.wiley.com/doi/10.1002/jmri.28574

Classic publication using Lead-DBS: In this article by Aibar-Durán et al., eight patients with treatment-resistant schizophrenia underwent DBS of the nucleus accumbens or subgenual cingulate with three-yea... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S0022395623002339

New publication using Lead-DBS: In this article by Sands et al., the authors describe a legal action by Las Vegas Sands Corp. against unknown registrants of multiple domain names listed in the case title. Check out the paper here 👇👇 https://doi.org/10.1089/glre.2016.201011

🎧 Tune in here 🎶 🎧 👇👇 https://stimulatingbrains.org/76-gyorgy-buzsaki-action-the-ultimate-source-of-knowledge/

Classic publication using Lead-DBS: In this article by Yang et al., the authors retrospectively analyzed Parkinson’s patients undergoing STN-DBS and showed that intraoperative stimulation-induced sweating was associate... Check out the paper here 👇👇 https://www.hindawi.com/journals/pd/2019/8180123/

Classic publication using Lead-DBS: In this article by Kern et al., the authors report that methylphenidate produced a significant suppression of subthalamic nucleus beta-band (13–30 Hz) LFP power in a Par... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S1935861X22000791

Classic publication using Lead-DBS: In this article by Feldmann et al., the authors tested whether Christmas-related events influence beta activity in Parkinson’s disease by analyzing chronic STN... Check out the paper here 👇👇 https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.29334

Classic publication using Lead-DBS: In this article by Nguyen et al., the authors report a case in which computerized postoperative lead localization and imaging guided revision of a subthalamic nucleus de... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S1935861X22001863

🎧 Tune in here 🎶 🎧 👇👇 https://stimulatingbrains.org/74-ludvic-zrinzo-beyond-technique-precision-evidence-humanity-functional-neurosurgery/