Classic publication using Lead-DBS: In this article by Sugiyama et al., the authors discuss the concept of using a single deep brain stimulation lead to stimulate both the thalamus and subthalamus as... Check out the paper here 👇👇 https://www.frontiersin.org/articles/10.3389/fnhum.2022.790942/full

New publication using Lead-DBS: In this article by Agashe et al., the authors tested whether thalamic local field potential spectral profiles can physiologically confirm centromedian–parafascicular targeting during DBS for dr... Check out the paper here 👇👇 https://doi.org/10.3389/fnins.2026.1855048

New publication using Lead-DBS: In this article by Barlatey et al., the authors tested the robustness of DBS lead reconstruction using two distinct postoperative CT scans per patient and found mean lead tip translation of 0.79 mm, ind... Check out the paper here 👇👇 https://doi.org/10.1159/000552349

Classic publication using Lead-DBS: In this article by Wang et al., the authors tested lateral habenula deep brain stimulation in a single treatment‑resistant depression patient, reporting safe bilate... Check out the paper here 👇👇 https://www.frontiersin.org/articles/10.3389/fpsyt.2020.616501/full

Classic publication using Lead-DBS: In this article by Li et al., the authors tested whether bilateral high-frequency STN‑DBS can directly suppress levodopa‑induced on‑dyskinesia in PD without reducin... Check out the paper here 👇👇 https://www.frontiersin.org/articles/10.3389/fneur.2021.595741/full

Classic publication using Lead-DBS: In this article by Germann et al., the authors tested whether fornix deep brain stimulation in Alzheimer's patients alters hippocampal atrophy and amyloid biomarkers and repo... Check out the paper here 👇👇 https://onlinelibrary.wiley.com/doi/abs/10.1002/alz.70394

Classic publication using Lead-DBS: In this article by Mason et al., the authors report a case of bilateral upper-limb postural and action tremor with progressive cervical dystonia that was responsive to ventral-inte... Check out the paper here 👇👇 https://tremorjournal.org/article/10.5334/tohm.673/

Classic publication using Lead-DBS: In this article by Wang et al., the authors report that lateral habenula deep brain stimulation in a single treatment‑resistant depression patient—implanted bilater... Check out the paper here 👇👇 https://www.frontiersin.org/articles/10.3389/fpsyt.2020.616501/full

Classic publication using Lead-DBS: In this article by Germann et al., the authors compared DBS and MRgFUS targeting in 118 essential tremor patients via stimulation/lesion mapping, probabilistic efficacy... Check out the paper here 👇👇 https://jnnp.bmj.com/content/early/2023/09/18/jnnp-2022-330795

Classic publication using Lead-DBS: In this article by Denys et al., the authors examined tolerability and effectiveness of bilateral deep brain stimulation of the ventral anterior limb of the internal ca... Check out the paper here 👇👇 https://psychiatryonline.org/doi/10.1176/appi.ajp.2019.19060656

Classic publication using Lead-DBS: In this article by Horn et al., the authors identified a structural and functional connectivity profile of effective subthalamic nucleus deep brain stimulation in Parkinson disea... Check out the paper here 👇👇 https://onlinelibrary.wiley.com/doi/10.1002/ana.24974

Classic publication using Lead-DBS: In this article by Sildatke et al., the authors recorded simultaneous EEG and nucleus accumbens local field potentials during a flanker task in four DBS-implanted p... Check out the paper here 👇👇 https://www.frontiersin.org/articles/10.3389/fnhum.2020.627564/full

Classic publication using Lead-DBS: In this article by Baldermann et al., the authors tested whether preoperative cortical thickness and DBS-connected streamlines predict response to nucleus basalis of Mey... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S1094715921021875

Classic publication using Lead-DBS: In this article by Zheng et al., the authors retrospectively analyzed sleep outcomes in 32 Parkinson's disease patients two years after GPi-DBS and mapped stimulation sites and fibe... Check out the paper here 👇👇 https://www.nature.com/articles/s41531-024-00800-4

Classic publication using Lead-DBS: In this article by Mei et al., the authors tested functional zonal image-reconstruction-guided programming for STN-DBS in Parkinson’s patients and found it reduced... Check out the paper here 👇👇 https://www.frontiersin.org/articles/10.3389/fneur.2022.916658/full

Classic publication using Lead-DBS: In this article by Han et al., the authors systematically reviewed DBS for extreme behaviors in ASD (nine patients) and used connectomic mapping of electrode locati... Check out the paper here 👇👇 https://thejns.org/view/journals/j-neurosurg/137/3/article-p699.xml

New publication using Lead-DBS: In this article by Anonymous et al., the authors report on Las Vegas Sands Corp.'s lawsuit against unknown registrants of multiple domain names (e.g., www.wn0000.com, www.wn1111.com, www.4456888.... Check out the paper here 👇👇 https://doi.org/10.1089/glre.2016.201011

Classic publication using Lead-DBS: In this article by Singh et al., electrical stimulation mapping of the anterior insula during stereo-EEG induced time-locked pathological crying and profound sadness in... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S2589986420300691

New publication using Lead-DBS: In this article by Bernardi et al., the authors describe a 15-year-old female with a novel DNAJC6-associated juvenile parkinsonism whose disabling, medication-refractory tremor was markedly and sustaina... Check out the paper here 👇👇 https://doi.org/10.5334/tohm.1187

Classic publication using Lead-DBS: In this article by Loeffler et al., the authors tested deep brain stimulation of the ventralis intermedius nucleus and adjacent subthalamic proj... Check out the paper here 👇👇 https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2022.1048530/full

Classic publication using Lead-DBS: In this article by Scerrati et al., the authors report on three patients with dystonic midline tremor treated with deep brain stimulation targeting the thalamic Ventral‑Oralis com... Check out the paper here 👇👇 https://link.springer.com/10.1007/s00415-024-12619-3

Classic publication using Lead-DBS: In this article by Horn et al., the authors introduce and validate a method to map neurosurgical AC/PC DBS electrode coordinates into MNI space without patient MRIs, tes... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S1053811917301088

Classic publication using Lead-DBS: In this article by Jorge et al., the authors tested the relationship between STN DBS contact location and voice in Parkinson disease and found that anterior sensorimotor STN stimulatio... Check out the paper here 👇👇 https://journals.lww.com/10.1093/neuros/nyaa024

Classic publication using Lead-DBS: In this article by Bardon et al., the authors tested whether subthalamic nucleus active-contact location affects improvement of Parkinson's non-motor symptoms and found no co... Check out the paper here 👇👇 http://biomed.papers.upol.cz/doi/10.5507/bp.2020.034.html

Classic publication using Lead-DBS: In this article by Martinez‐Nunez et al., the authors investigated structural and functional connectivity correlates of earlier symptom improvement after bilate... Check out the paper here 👇👇 https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.70152

Classic publication using Lead-DBS: In this article by Warren et al., the authors report a single-center series of centromedian nucleus deep brain stimulation in six children with Le... Check out the paper here 👇👇 https://thejns.org/view/journals/j-neurosurg-case-lessons/10/12/article-CASE25478.xml

So looking forward for this! It’ll be a late night chat for me, but any time is a good time to talk about exciting science 🧠⚡️

We are excited! #OHBM2026 – three @netstim.org papers by Aysu Sahin, Patricia Zvarova & Maike Mustin! 👇👇

Classic publication using Lead-DBS: In this article by Balachandar et al., longitudinal GPi-DBS recordings in ten children showed that status dystonicus is associated with increased periodic pallidal beta-band power a... Check out the paper here 👇👇 https://www.nature.com/articles/s41467-025-64416-9

Classic publication using Lead-DBS: In this article by Bouwens Van Der Vlis et al., the authors analyzed outcomes in eight refractory OCD patients treated with ventral capsule/ventral striatum DBS and used... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S1094715921000891

Classic publication using Lead-DBS: In this review by Piper et al., the authors summarize evidence on epileptic network mechanisms and multimodal mapping—highlighting thalamic propagation points (anterior and... Check out the paper here 👇👇 https://academic.oup.com/brain/article/145/10/3347/6623456

Classic publication using Lead-DBS: In this article by Buijink et al., the authors recorded thalamic local field potentials with a sensing-enabled implanted DBS pulse generator (Medtronic Percept PC) in an... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S2467981X22000129

For the next stimulating brains talk session, we're going to span across three continents with @carobellum.bsky.social and @macshine.bsky.social! Join us on June 25th at 6 PM EST (11 PM BST/8 AM AEST next day) for another amazing session! Free to attend 🎉 👉 talks.stimulatingbrains.org

Fantastic new work in the pipeline in both labs - exactly in the spirit of #optoDBS. So excited by this line of work and this fantastic shared keynote!

The collaboration between @julianneumann.bsky.social and @yttrilab.bsky.social that led to this years keynote seems like a match made in heaven. But in fact, the two met at #optoDBS 2017!

And were live! #optoDBS 2026 is oft to a great start here at Campus Biotech in Geneva. Christian Lüscher kicking off the conference - and since we are broadening the scope a lot: will we call it #optoMOD in the future?

Classic publication using Lead-DBS: In this article by Peisker et al., the authors tested whether nucleus accumbens deep brain stimulation alters delay discounting in nine patients with substance use disorders (DBS on vs after a 24... Check out the paper here 👇👇 http://www.mdpi.com/2076-3425/8/2/21

🎧 Tune in here 🎶 🎧 👇👇 https://stimulatingbrains.org/56-harith-akram-connectomic-dbs-sweetspots-and-building-a-supercomputer/

Classic publication using Lead-DBS: In this article by Zhao et al., they prospectively tested whether preoperative quantitative susceptibility mapping of iron distribution in the substantia nigra, subthalamic nucl... Check out the paper here 👇👇 https://onlinelibrary.wiley.com/doi/10.1002/jmri.28574

Classic publication using Lead-DBS: In this article by Aibar-Durán et al., eight patients with treatment-resistant schizophrenia underwent DBS of the nucleus accumbens or subgenual cingulate with three-yea... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S0022395623002339

New publication using Lead-DBS: In this article by Sands et al., the authors describe a legal action by Las Vegas Sands Corp. against unknown registrants of multiple domain names listed in the case title. Check out the paper here 👇👇 https://doi.org/10.1089/glre.2016.201011

🎧 Tune in here 🎶 🎧 👇👇 https://stimulatingbrains.org/76-gyorgy-buzsaki-action-the-ultimate-source-of-knowledge/

Classic publication using Lead-DBS: In this article by Yang et al., the authors retrospectively analyzed Parkinson’s patients undergoing STN-DBS and showed that intraoperative stimulation-induced sweating was associate... Check out the paper here 👇👇 https://www.hindawi.com/journals/pd/2019/8180123/

Classic publication using Lead-DBS: In this article by Kern et al., the authors report that methylphenidate produced a significant suppression of subthalamic nucleus beta-band (13–30 Hz) LFP power in a Par... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S1935861X22000791

Classic publication using Lead-DBS: In this article by Feldmann et al., the authors tested whether Christmas-related events influence beta activity in Parkinson’s disease by analyzing chronic STN... Check out the paper here 👇👇 https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mds.29334

Classic publication using Lead-DBS: In this article by Nguyen et al., the authors report a case in which computerized postoperative lead localization and imaging guided revision of a subthalamic nucleus de... Check out the paper here 👇👇 https://linkinghub.elsevier.com/retrieve/pii/S1935861X22001863

🎧 Tune in here 🎶 🎧 👇👇 https://stimulatingbrains.org/74-ludvic-zrinzo-beyond-technique-precision-evidence-humanity-functional-neurosurgery/

New publication using Lead-DBS: In this article by Calvano et al., the authors tested the spatial correspondence between Brainlab Elements automated STN segmentations and multi-atlas segmentation versus postoperative volumes... Check out the paper here 👇👇 https://doi.org/10.1007/s00701-026-06930-3

Classic publication using Lead-DBS: In this article by Boutet et al., the authors mapped sign-specific STN-DBS “hot” and “cold” spots for tremor, rigidity, bradykinesia and axial signs... Check out the paper here 👇👇 https://academic.oup.com/braincomms/article/doi/10.1093/braincomms/fcab027/6168427