A wave of new papers discuss the merits and limitations of lesion network mapping. #neuroskyence By @avaskham.bsky.social www.thetransmitter.org/brain-imagin...

1/9 New preprint by Laurin Mordhorst: 3D histology validates 2D histology for axon radius distributions and conduction velocities. We asked: if individual axons vary along their length, can classic 2D histology still reflect white-matter organization? Link: www.biorxiv.org/content/10.6...

Correlating brain maps across datasets is everywhere in neuroimaging. Here we ask: when you contextualize a brain map against genes, metabolism, or connectivity... What can you really conclude? How can we do better? We explore these questions here: tinyurl.com/2dudkevc

The LNM debate keeps developing. www.nature.com/articles/s41... @andrewzalesky.bsky.social @natneuro.nature.com #neuroskyence

Organization of neuropeptide systems in the human brain | doi.org/10.1038/s415... Neuropeptides are functionally diverse signaling molecules in the brain and body. @cebric.bsky.social curates an atlas of neuropeptide receptors and relates it to brain function @natneuro.nature.com 🧩 🧠 ⤵️

🚨 New preprint alert! 🚨 Transdiagnostic latent factor models of psychopathology are widely assumed to improve brain-behaviour associations. So we decided to test this directly and found that they don't. A short 🧵 Link: www.biorxiv.org/content/10.6... 1/10

🧠 Resting-state fMRI is often treated as the gold standard for studying the brain’s intrinsic organization. But is it actually the best way to estimate functional architecture? We tested this directly. 🧵1/8

I couldn't find a tool to plot different #neuroimaging data in one consistent style, so I made one! Meet yabplot (yet another brain plot) - a #Python package for (sub)cortex & tracts.🧠 - Simple API - Built-in atlases - Custom atlas support 🔗 github.com/teanijarv/ya... (drop a ⭐️!)

neuromapr 0.2.1 has been accepted and published on CRAN! Very excited to get this out to users in the simplest way possible, and hope the #rstats #neuroimaging community finds it useful! lcbc-uio.github.io/neuromapr/

A recent @natneuro.nature.com paper analyzed lesion network mapping and raised concerns about the validity of the method. See below 👇 for our response. www.biorxiv.org/content/10.6...

A recent paper in @natureportfolio.nature.com raised concerns about the lesion network mapping method. Our team of 16 coauthors analyzed >1000 lesions and 34 symptoms and found that "The methodological foundations of lesion network mapping remain sound" www.biorxiv.org/content/10.6...

📢 DGKN 2026: Congress for Clinical Neurosciences with Continuing Education Academy 📅on 25 February 2026, Prof. Dr. Thomas Wolfers will present a talk titled: “𝗠𝗮𝗰𝗵𝗶𝗻𝗲 𝗟𝗲𝗮𝗿𝗻𝗶𝗻𝗴 𝗮𝗻𝗱 𝗕𝗶𝗴 𝗗𝗮𝘁𝗮 𝘁𝗼 𝗣𝗮𝗿𝘀𝗲 𝗜𝗻𝗱𝗶𝘃𝗶𝗱𝘂𝗮𝗹 𝗗𝗶𝗳𝗳𝗲𝗿𝗲𝗻𝗰𝗲𝘀” @thomaswolfers.bsky.social #DGKN2026 #ClinicalNeuroscience #BigData #ML

New preprint: Revisiting the methodological foundation of lesion network mapping. doi.org/10.64898/202... A thread.

"You see what you look for, and you look for what you know." We are proud to release FOCUS: a 100 μm deformable human subcortical atlas precisely registered to MNI space. www.biorxiv.org/content/10.6...

The extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)! Preprint: www.biorxiv.org/content/10.6... Website: anniegbryant.github.io/subcortex_vi...

netneurotools: a trainee-oriented approach to network neuroscience | doi.org/10.1101/2025... Our lab’s internal toolkit for accomplishing everyday tasks in brain imaging ⤵️

🍤 hippocampus = the brain's memory machine 🍤 unique cytoarchitecture, highly connected with multiple networks, & very variable across individuals video shows hippocampal shape variations across 250-ish young HCP adults study hippocampus with open tools like hippomaps doi.org/10.1038/s415...

1/ Our new paper is out in Imaging Neuroscience! 🎉 We validated in-vivo MRI–based axon radius mapping by comparison to large-scale human brain histology (> 46 M axons & 35 CC-ROIs). Title: “MRI-scale histology validates spatial sensitivity of in-vivo MRI-based axon radius estimation”

After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:

Excited to share our new study, “Mapping the Association of Cerebral Small Vessel Disease, Gray Matter Integrity, and Cognitive Function”, now published in Neurology. Paper: www.neurology.org/doi/10.1212/... Editorial: www.neurology.org/doi/10.1212/...

🚨 New paper in Nature Methods: HippoMaps: multiscale cartography of the human hippocampus Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG) Led by @jordandekraker.bsky.social docs: hippomaps.readthedocs.io paper: doi.org/10.1038/s415...

This great piece by @addyosmani.bsky.social resonates strongly with my recent experience using AI coding agents

Do you ever wish you could just use python to pull together the files and code for running FSL's randomise? Me too! I made this: github.com/jmumford/ran... It will even replace the numbers in the file outputs with contrast names of your choosing (and replace corrp with 1minusp).

Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date. We're very happy to announce that we are able to reduce the APC to $1400. Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.

Great new article by Matthijs Biesbroek and the Meta VCI Map Consortium now published in Stroke. "Signature White Matter Hyperintensity Locations Associated With Vascular Risk Factors Derived From 15 653 Individuals" www.ahajournals.org/doi/full/10....

🚨 New preprint out! 🚨 “Translating the Transcriptome: A Connectomics Approach for Gene-Network Mapping and Clinical Application” 🔗 doi.org/10.1101/2025...  🧵 A short thread:

I've been thinking a lot about the preprint in terms of my own career. I grew up academically in computational labs. My papers were abstract early on and they only got more abstract as I progressed. The model was: find a new exciting mathematical tool. Apply it to brain imaging data. Write it up. 1/

I still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...

Integrating and interpreting brain maps | doi.org/10.1016/j.ti... Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️

🧠 NEW PREPRINT Many-Two-One: Diverse Representations Across Visual Pathways Emerge from A Single Objective www.biorxiv.org/content/10.1...

Check out our new review/perspective (w/ @juangallego.bsky.social & Devika Narain) on neural manifolds in the brain! It was a lot of fun to think through these ideas over the past couple of years, and I'm excited it's finally out in the world! 🔗: www.nature.com/articles/s41... 📄: rdcu.be/ex8hW

1 To predict the behaviour of a primate, would you rather base your guess on a closely related species or one with a similar brain shape? We looked at brains & behaviours of 70 species, you’ll be surprised! 🧵Thread on our new preprint with @r3rt0.bsky.social , doi.org/10.1101/2025...

How can we best use AI in science? Myself and 9 other research fellows from @imperial-ix.bsky.social use AI methods in domains from plant biology (🌱) to neuroscience (🧠) and particle physics (🎇). Together we suggest 10 simple rules @plos.org 🧵 doi.org/10.1371/jour...

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements... doi.org/10.1038/s415...

When you smell a rose, more than 800 different odorants enter your nose and bind to olfactory receptors expressed in the cell membranes of various neurons, which fire to create a pattern interpreted by the brain. www.quantamagazine.org/how-smell-gu...

Kidney Function and Cerebral Small Vessel Disease bit.ly/HeinzeRL25 (FREE) @felenae.bsky.social @petersenm.bsky.social #CKD

The splendour of unthresholded brain maps apertureneuro.org/article/1406...

NetNeuroLab posters + talks at @ohbmofficial.bsky.social synapse types! neurotransmission connectomes! mouse maps! neuromorphic networks! generative models! neuropeptides! ⤵️

NSB Lab (past & present) has a host of workshops, talks, symposia, and posters to present at #OHBM2025! On Tuesday, Daniel Margulies and @alexfornito.bsky.social are running the educational session on Brain Modes, Components, and Gradients. Interested in whole-brain structure and function...?

Amazing new paper on individual development of E/I balance during adolescence, first-authored by @amnsbr.bsky.social! Read @ Science Advances: www.science.org/doi/10.1126/... Bonus: Amin developed a tool to run biophysical network modelling on GPUs – because why shouldn't he? cubnm.readthedocs.io

RELEASE THE KRAKEN(CODER)! Ever struggle deciding which connectome pipeline to use or want to map between structure and function? Our multi-modal connectome mapping and fusion tool-the Krakencoder-can help! Brilliant Keith Jamison led this work, code available! www.nature.com/articles/s41...

I am currently at #ESOC2025 with the @csi-lab.bsky.social to present latest findings on #sleep and cerebral small vessel disease ( #CSVD ) ❤️ Big thanks to the whole team for this wonderful dataset including excellent #neuroimaging 🧠

Presented at #ESOC2025 The StroCare trial reports no change in self-assessed quality of life, but shows positive impact on functional outcome. CSIs Dr Rafael Bourry (@rbourry.bsky.social) breaks down the findings, watch the @VJNeurology.bsky.social interview here: www.vjneurology.com/video/skcgce...

At #ESOC2025, Thies Ingwersen presented findings on lesion patterns associated with first-time atrial fibrillation after ischemic stroke. A step forward in stroke-related AF risk stratification. #StrokeResearch #Neuroimaging #AFib #BrainLesions

Our team presented the primary endpoint results of the STROCARE trial at #ESOC2025. Findings showed comparable physical QoL (PROMIS-10) at 12 and 24 months between control and intervention groups. Great to see our work featured on the big stage! 🧠#StrokeResearch #STROCARE #QoL #RCT

Better Code, Better Science - Introducing a new open-source book project on scientific coding using AI tools russpoldrack.substack.com/p/better-cod...

MR guided focused ultrasound surgery is an effective and uprising treatment option for Essential tremor. But where is the optimal site to sonicate? Which spots to avoid due to side-effects? @science.org @braincircuits.bsky.social @netstim.org – a thread🧵! www.science.org/doi/10.1126/...

I am so very proud announce my lab's first preprint!! @xiaoyucaly.bsky.social delves into the mechanisms driving tau distribution: * Tau sequence driven by connectivity dynamics * Tau load driven by local factors Check out her thread below

Our #metaanalysis (n = 231) in JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus Short-term sleep deprivation shows a distinct picture, affecting the thalamus jamanetwork.com/journals/jam...