One of the most beautiful, comprehensive, large scale studies of dMRI outputs I've ever seen. The amount of work and thought required was truly massive, but the results are clear and will be guiding how I think about these dMRI measures going forward. I replicated @stevenmeisler.com's analyses

Diffusion MRI (dMRI) is a powerful tool to study white matter maturation. In our new preprint, we process and distribute a new resource of >24,000 ABCD dMRI scans using open source tools! We then evaluate how methods shape inferences about development. 🔗 www.biorxiv.org/content/10.6...

🍄 Our new living systematic review and meta-analysis on MDMA for PTSD is now live on medRxiv. Here's what we found and how we built upon our open science infrastructure to support it 🧵 www.medrxiv.org/content/10.6...

🏔️ Announcing IST 2026 in the Canadian Rockies! The 2nd annual meeting of the International Society for Tractography is happening this fall. Following Bordeaux, we’re gathering researchers, clinicians & developers pushing tractography, diffusion MRI & brain connectivity forward.

We think of white matter as the highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My final PhD paper, “Two Axes of White Matter Development”, is now out in @natcomms.nature.com! 🛣️🧠✨ 🔗 bit.ly/wm2axes

Ever wondered how white matter tracts actually map onto the cortical hierarchy and cognition—beyond the usual “projection vs association” labels? Our new preprint tackles exactly that! 🧠✨ doi.org/10.64898/202... Thread below 🧵

Excited to share that our new review, "Depression as a disease of white matter network disruption: Learning from Multiple Sclerosis," is out now in Biological Psychiatry! We propose MS as a powerful model for studying how white matter network changes contribute to depression.

BEYOND delighted to see two brilliant #PennLINC alumni -- @valeriejsydnor.bsky.social + @lindenmp.bsky.social -- named by The Transmitter as "Rising Stars of Neuroscience 2025". Super well deserved -- CONGRATS!!! www.thetransmitter.org/early-career...

🧠I am excited to announce that our manuscript introducing a new data resource – PennLEAD (Penn Longitudinal Executive functioning in Adolescent Development) – is now available on bioRxiv. Below are some details highlighting our data resource🧵funded by NIMH R01MH113550 www.biorxiv.org/content/10.1...

After years of development and testing, we are happy to present our work in "Diffusion MRI Processing in the HEALthy Brain and Child Development Study: Innovations and Applications"! www.biorxiv.org/content/10.1.... A thread:

Join us for the #NeuroHackademy Neuroimaging and Data Science networking event at this year's @sfn.org meeting. Tues. Nov. 18th from 7–9pm at the Marriott Marquis, Grand Ballroom 4. The event is free; food and drink will be available for purchase from the hotel.

🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging. 👇🧵 nature.com/articles/s41... #Neuroscience #Psychedelics #BrainImaging

Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉 📚 Read the paper: authors.elsevier.com/c/1lpaF3BtfH... 🧠 Explore the RBC dataset: reprobrainchart.github.io

New preprint from stellar IRTG PhD student Amelie Rauland + team on white matter bundle reconstruction! Shows that WM bundles can be reliably extracted from simple 32-direction dMRI & features predict cognition - huge potential for legacy and clinical data. Thread 👇 www.biorxiv.org/cgi/content/...

New paper alert! This paper describes the work that we have been doing in the last few years to create a software ecosystem for tractometry that is extensible, interoperable, and generally useful.

Looking for @theabcdstudy.bsky.social fMRI timeseries data?It's all in the 6.0 data release, thanks to @drdamienfair.bsky.social and team at ABCC 🧠: docs.abcdstudy.org/latest/docum...

(1/4) Our recent work shows DTI-ALPS is confounded by white matter geometry (crossing fibers, undulation, dispersion), ALPS-asymmetry signature (ALPS measures asymmetry of diffusion) occurs throughout all WM, and ALPS-WM is not always orthogonal to PVS onlinelibrary.wiley.com/share/TPCABU...

SO COOL

Alert! ... for the child development world! @fluxsociety.bsky.social @fitngin.bsky.social ‪ The Healthy Brain and Child Development (HBCD) Study has released its first data wave - it’s massive. Check here: docs.hbcdstudy.org and here: nbdc-datahub.org Here’s why it matters 🧠🍼

(1/18) Now out on BioRxiv‼️ Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | doi.org/10.1101/2025... Funded by National Institute of Mental Health (NIMH)

I'm a huge fan of this project

@kevin-y-sun.bsky.social‬ will be presenting his work on "Copy Number Variant Risk Scores Are Associated with Personalized Functional Brain Network Topography" Wed, June 25, 13:15 - 15:15 & Thus, June 26, 13:45 - 15:45

@audreycluo.bsky.social will be presenting her fab work on "Two Axes of White Matter Development" on Wed, June 25, 13:15 -15:15 & Thurs, June 26, 13:45 -15:45; Poster #1010.

@goliashf.bsky.social is ALSO presenting "Systematic dynamical profiling to discover and manipulate the dynamical regime of the primate brain" Thursday, Jun 26: 9:00 AM – 10:15 AM during the computational dynamics symposium in Room M2.

@goliashf.bsky.social is presenting (via video, 🥲) "Reproducible Brain Charts: An Open Data Resource for Mapping the Developing Brain and Mental Health" on Friday, Jun 27: 11:30 AM – 12:45 PM. This talk is part the Neuroinformatics and Data Sharing session in Room M3 (Mezzanine Level).

@stevenmeisler.com is presenting "A quality-rated, analysis-ready release of 26,174 dMRI sessions from the ABCD Study" Friday / Saturday 1810. Wooo!!!!

The Baller Lab is thrilled to announce that @elenaccooper.bsky.social just had her first first-author publication! “Investigating mood and cognition in people with multiple sclerosis: a prospective cross-sectional study protocol” is now published on BMJ Open: bmjopen.bmj.com/content/15/5/e094733! 🧠

Some very cool imaging sequences in this one

THRILLED to see this SI now out addressing the power and potential of focusing our lens on women. H/t to Tali for making space for these ideas to flourish and for a dream team of investigators to contribute!! Advancing the science of women’s health | Science Advances www.science.org/doi/10.1126/...

Big update to CuBIDS! Now with even more precise descriptions of protocol variations in your BIDS data.

I've been involved with this project since the very beginning and am very happy with how it ultimately turned out. The curation and processing was absolutely painstaking. Congratulations @goliashf.bsky.social on an excellent paper!!

Do you work on surface MRI such as HCP data? Our paper is finally out in Imaging Neuroscience, showing biases in surface fMRI. The revised ms has many new insights! TLDR: Vertices are much closer to each other in sulci, resulting in (fake) high spatial autocorrelation. (1/5)

It's hard to overstate what a big deal this paper is: onlinelibrary.wiley.com/doi/10.1002/.... Head motion in dMRI is NOT like head motion in BOLD.

Cortical maturation unfolds hierarchically, endowing the PFC with extended plasticity. But do timeframes of plasticity vary across PFC layers? With 7T quantitative myelin imaging, EEG, and cognitive data, we uncover heterochronous laminar maturation in the PFC 1/n. www.biorxiv.org/content/10.1...

Finally out in its polished form 🤩 New methodological avenues that help facilitate looking at individual brain functional organization in developmental populations 👶🧠

The scipy conference is one of the most welcoming and most inspiring conferences I have ever attended. It's at the center of a network of collaborators that work together across many different disciplines and sectors to improve scientific computing openly and broadly.

We are super excited about this -- the SYPRES initiative for living systematic reviews on clinical trials of psychedelics in psychiatry. All credit to @parkersingleton.bsky.social and the team at #PennLINC + #ACTTION.

Psychedelic mental health research is booming—but how do we keep up with rapidly evolving evidence? 🌱 Our team proposes a living evidence synthesis approach to ensure clinicians, policymakers, and the public have access to the latest, most reliable data. 🔗 www.nature.com/articles/s44... 🧪🧵

Weak and unstable prediction of personality from the structural connectome direct.mit.edu/imag/article...

Hi Adam, I take your point that the quadratic formula can be presented in a way that does not inspire understanding or affection. And it sounds like that's how it was taught to you. So let me try to make a better case for it. Here's how I discussed it in my book The Joy of x. (1/9)

The limiting factor for MRI based prediction of behavioral traits may be neither the imaging nor the pipeline or learning algorith but rather the reliability of the target phenotypes Thought provoking work my Martin Gell et al: www.nature.com/articles/s41...

Spoiler alert: Yes Can ephapticity contribute to brain complexity? journals.plos.org/plosone/arti... #neuroscience

hey -- i'm hiring a postdoc! the ad will be up shortly, but looking for someone with network neuroscience experience (very broadly). the position isn't tied to any specific project/grant, so lots of flexibility in terms of what you'd actually *do*. hmu if you might be interested/want to learn more!

Good news everyone! A new version of graph-tool is just out! @graph-tool.skewed.de graph-tool.skewed.de Graph-tool is a comprehensive and efficient Python library to work with networks, including structural, dynamical, and statistical algorithms, as well as visualization. 1/N #networkscience

Grateful to the OHBM communications committee (curiously not yet here?) and particularly to @audreycluo.bsky.social for putting together this interview with yours truly: www.ohbm-com.com/blog/intervi..., in which I had the opportunity to hold forth on my educational motivations and philosophy

Check it out! The future of Neurosynth. We launched Neurosynth Compose: A free and open platform for neuroimaging meta-analysis. NS-Compose makes it easy to perform custom neuroimaging meta-analyses without leaving the browser. It's live, check it out! compose.neurosynth.org

@tsalo.bsky.social relevant

Finally, we want to thank the users who have provided feedback and opened bug reports, especially @erikglee.bsky.social and Janice Hau, who have provided invaluable feedback on these recent developments. 10/10

Special thanks to @cieslakmatt.bsky.social @tsalo.bsky.social @stevenmeisler.com @adamraikes.bsky.social @arokem.bsky.social @cookni1.bsky.social for their work getting things over the finish line these last few months. 9/10