✨ SHINY NEW PAPER ✨ Sleep-disordered breathing is associated with higher Aβ burden, lower rFDG, and worse cognition in Alzheimer's Disease. @sbe.bsky.social www.sciencedirect.com/science/article/pii/S0197458025001034

Excited to see this work published in @natcomms.nature.com! 🧠📊 In-vivo evidence of E/I alterations underlying functional changes in individuals with autism in the large ABIDE1 dataset AND replication in the independent ABIDE2 dataset.

New preprint from stellar IRTG PhD student Amelie Rauland + team on white matter bundle reconstruction! Shows that WM bundles can be reliably extracted from simple 32-direction dMRI & features predict cognition - huge potential for legacy and clinical data. Thread 👇 www.biorxiv.org/cgi/content/...

The end of a PhD journey 🎓 What a ride - full of lovely people, exciting science, coding tunnels, coffee-brainstorms & amazing conferences! Whole-hearted thank you to all who shared the journey & celebrated with me - especially @sofievalk.bsky.social, @sbe.bsky.social &@mps-cognition.bsky.social 💐🥳❤️

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements... doi.org/10.1038/s415...

Amelie Rauland (all star via IRTG student w/ @sbe.bsky.social ) will be presenting "Benchmarking Reconstruction Methods for Bundle Segmentation in Single-Shell dMRI" on Friday and Saturday, Poster #1283

#ABCD-J #Studienhighlights: Eine kürzlich erschienene Studie zeigt mittels #JTrack Social Unterschiede in Kommunikationsmustern zwischen neurotypischen Erwachsenen und Erwachsenen mit #Autismus-Spektrum-Störung auf. Neugierig geworden? Das ganze Highlight gibt es hier: www.abcd-j.de/de/showcases...

🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence? We asked this in our new paper just out in #ScienceAdvances ✨ “Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling” 📄 www.science.org/doi/full/10.... 🧵⤵️

⭐ new paper Maturation of cortical excitation-inhibition (EI) in adolescence now in Science Advances 💥 A true tour de force of multimodal MRI, connectomics & GPU-powered 🤖!! biophysical modelling by hiball superheroes 🦸‍♂️🦸‍♀️🦸‍♂️ @amnsbr.bsky.social @sofievalk.bsky.social @sbe.bsky.social

Our #metaanalysis (n = 231) in JAMAPsych reveals consistent brain abnormalities across #sleep disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus Short-term sleep deprivation shows a distinct picture, affecting the thalamus jamanetwork.com/journals/jam...

It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠

Always thought we should use connectivity blueprints to investigate differences between human, chimpanzee, and macaque brains? www.jneurosci.org/content/earl... For Katherine Bryant’s latest masterpiece.

NOW, Join if you're interessted Topic: DGKN Hackroom 2025 — Tool Talks Time: Mar 14, 2025 10:30 - 12h fz-juelich-de.zoom.us/j/6792251876... Data Management: 10:30 – 11:00 Datalad: GPDR conform collaboration Jtrack: remote wearable assessment

Now out in NPJ Digital Medicine our manuscript on real-world evidence for altered communication preferences in autism: nature.com/articles/s41... @sbe.bsky.social @leoschilbach.bsky.social

A new #Neurosalience episode is out! 🧠 From Big Data to Biomarkers with Peter Bandettini @fmri-today.bsky.social and Simon Eickhoff @sbe.bsky.social youtu.be/z91SiENsgF8

Dazu integrieren wir – das Institut für Neurowissenschaften und Medizin: Gehirn und Verhalten (INM-7) @fz-juelich.de, und unsere klinischen Partner an den Unikliniken Aachen, Bonn, Köln, und Düsseldorf – verschiedene technische Lösungen zu einer digitalen Plattform und vernetzen uns.

Thanks to everyone's feedback, we have updated our calculator to optimize sample size N & scan time T for fMRI studies: leonoqr.github.io/ORSP_Calcula... The first new feature is that users can explore how different N & T leads to different accuracy, e.g., N=1000 & T=30min => 81% max accuracy. 🧵

The limiting factor for MRI based prediction of behavioral traits may be neither the imaging nor the pipeline or learning algorith but rather the reliability of the target phenotypes Thought provoking work my Martin Gell et al: www.nature.com/articles/s41...

This is what happens if preprints are treated as „scientific literature“ Don’t get me wrong, I am all for preprinting. But unfortunately, it is often ignored that anybody can preprint anything

We created a #neuroinformagical (obvs) starter pack! Let us know who else to add! #openscience #datasharing #neuroskyence 🧪 go.bsky.app/LRqnaMP

woo hoo - fantastic new work from ‪@wanb.bsky.social‬ @sofievalk.bsky.social @sbe.bsky.social & many more on microstructural asymmetry now out in Nature Comms ⤵️

Looked into BlueSky a while ago… really empty at that time X becoming useless for interesting reads and discussions on science send me in a social-media hiatus Back now and excited about things to come

Useful reminders from @sbe.bsky.social about #neuroimaging analysis #reproducibility at #OHBM2024: - Different atlases lead to different connectivity matrices. - The target *massively* matters. - ML algorithms just *love* shortcuts.

Lots to enjoy in this new paper by Sam Vickery @sbe.bsky.social and others. Brain areas in humans that show the greatest expansion from chimp -> human are the areas that are most susceptible to to the effects of aging www.science.org/doi/10.1126/...

We are looking for a community manager and development coordinator for DataLad !! The full description with contact info is at: files.inm7.de/mih/position...

Spread the word 📣 Announcing the first BrainHack at the DGKN meeting next month !! After being a staple at OHBM, this will be the first hackroom at a German (clinical) neuroscience meeting Enjoy the spirit of open science with tutorials, hackathons and an unconference 🔜 Join us in Frankfurt

Somehow it seems that computational models were immune to the current sample-size worries in #neuroimaging Turns out they are not 😱 DCM models and connections need 100+ subjects to give stable results New work by Alexander Silchenko & Felix Hoffstaedter: onlinelibrary.wiley.com/doi/10.1002/...

That is a really important result. These models are being run on an n of 12 or 20.

Somehow it seems that computational models were immune to the current sample-size worries in #neuroimaging Turns out they are not 😱 DCM models and connections need 100+ subjects to give stable results New work by Alexander Silchenko & Felix Hoffstaedter: onlinelibrary.wiley.com/doi/10.1002/...

Finally in the public 🚀 JuLearn: an easy-to-use library for leakage-free evaluation and inspection of ML models JuLearn is an open-source Python library simplifying the entry into the ML world -> design & evaluate ML pipelines without encountering common pitfalls arxiv.org/abs/2310.12568

Fantastic but very worrisome work by Sami Hamdan: Confound removal in machine learning can itself lead to leakage -> After information about the target from the features using standard approaches you can STILL predict it well academic.oup.com/gigascience/... #neuroskyence #MLSky #neuroimaging

Finally out 🎉 - our meta-analysis of 403 neuroimaging studies on language (3/3) Quite some functional specialization in subcortical areas, too. This and many more details can be found here: psycnet.apa.org/fulltext/202... Paper is open access !!

Finally out 🎉 - our meta-analysis of 403 neuroimaging studies on language (2/3) We ended up discovering truly subdomain-specific brain areas in spite of substantial covergence Functional specialization was most pronounced in the cortex but we also found considerable cerebellar effects

Finally out 🎉 - our meta-analysis of 403 neuroimaging studies on language (1/3) In addition to providing robust evidence on the engagement of classical language regions during language tasks, we also investigated the processing of linguistic subdomains: semantics, syntax, phonology and pragmatics!

Just wondering, am I the only person living (and loving) inbox-zero for years? I use my inbox as a todo list and make extensive use of „defer / put back“. Works amazing and each time I am back to empty it feels rewarding

A main goal of our institute is to provide open software & resources - DataLad (data-management) - JTrack (mHealth / wearable suite) - JuLearn (user-friendly ML library) - ANIMA (meta-analyses results) - JuSpace (MRI-PET integration) - many more... Full catalogue: www.fz-juelich.de/en/inm/inm-7...

Pitching skeptical views on #neuroimaging and machine-learning at the rating-state Brain conference. That meeting fully reflected my split feelings at the moment. The conference was stimulating, meeting colleagues was fun and discussions exciting. But travel is simply annoying

So, let's share some science. 🤓 This is my latest preprint, first-authored by Natalia Chechko. We tracked temporal trajectories of resting brain-function in healthy mothers from 1 week to 6 months after childbirth. doi.org/10.1101/2023... #Neuroscience #MedSky #PsychSciSky #Neuroimaging 🧵1/n

My (likely) last paper in Neuroimage: A systrematic evaluation of ALE meta-analyses for morphometric data, i.e., Anatomical Likelihood Estimation. www.sciencedirect.com/science/arti...

Hello world! Just arrived from twitter... Here is a recent paper from my lab :) Brain Networks and Adolescent Alcohol Use jamanetwork.com/journals/jam...

Interested in research data management, git-annex and DataLad Need to get your #neuroscience data organized? Need to deal with distributed data, provenance tracking or pipeline management? Join us at distribits in Düsseldorf - easy travel & great beer fosstodon.org/@distribits/...

Actually, emotion and cognition may not be so separate after all. There are phenotypic correlations and a shared genetic component. Anatomically, the key zone of convergence seems to be the superior frontal cortex. More details: www.sciencedirect.com/science/arti...

Not sure, how many are here already to whom this would be of interest, but I‘ll try All others, please share 🙏🏽 We are currently considering to strengthen open (#neuroimaging) science in the German clinical societies like DGKN, DGPPN etc. Would you like to contribute / engage / help ?

What a tour de force on personality factors, brain health & #neuroskyence: www.nature.com/articles/s44... Includes relationship with multiple diseases, analysis of modulating factors and #neuroimaging Large sample and long follow-up. But why use items as proxies rather than actual Big-5 scores?