✨SHINY NEW PAPER ✨ High depressive symptoms in a diverse cohort of healthy control and MCI participants were linked to higher plasma NfL and p-tau181 levels, but not Aβ42/40 www.sciencedirect.com/science/arti...

✨ SHINY NEW PAPER ✨ Atlases for tau-PET staging can be optimized by segmenting in native space and smoothing at 6mm www.sciencedirect.com/science/arti...

📚 NEW ISSUE 📚 Articles cover optimized atlases for tau-PET staging, depressive symptoms and MR spectroscopy biomarkers of early AD, and more. www.sciencedirect.com/journal/neur...

✨ SHINY NEW PAPER ✨ Across 3 datasets (3000+ participants), GFAP in both CSF and plasma consistently mediated the effect of age on cognitive impairment and dementia (MCI/AD incidence) www.sciencedirect.com/science/arti...

✨ SHINY NEW PAPER ✨ Treatments targeting inflammation (DHCA) and neuronal activity (Mal-gluc) significantly improved recognition memory in 3xTg-AD mice, but did not reduce p-Tau or Aβ burden www.sciencedirect.com/science/arti...

✨ SHINY NEW PAPER ✨ Tau relates to MR spectroscopy estimates of N-acetylaspartate and myo-inositol in cognitively-unimpaired amyloid-positive adults @elizabethhead.bsky.social www.sciencedirect.com/science/arti...

✨ SHINY NEW PAPER ✨ MRI-based diffusion metrics are higher in aged macaques in the central tegmental tract, an ascending projection from the locus coeruleus www.sciencedirect.com/science/arti...

📚 NEW ISSUE 📚 Articles cover age-related structural differences in the fischer brown Norway rat and bonnet macaques, apraxis deficis in Alzheimer's Disease, proteomic markers of aging, and more. www.sciencedirect.com/journal/neur...

✨ SHINY NEW PAPER ✨ Markers of cerebral small-vessel disease (white-matter lesions, lacunes) and vascular risk (e.g., hypertension, BMI) relate to faster 5-year decline in striatal dopamine (DRD2) @lipmpib.bsky.social www.sciencedirect.com/science/arti...

✨SHINY NEW PAPER ✨ Higher pulse wave velocity is associated with white matter microstructural damage in older adults 12 years later www.sciencedirect.com/science/arti...

📚 NEW ISSUE 📚 Articles cover pulse-wave velocity, cerebral small vessel disease, choroid plexus volume, hearing loss, and racial discrimination in aging, and more. www.sciencedirect.com/journal/neurobiology-of-aging/vol/156/suppl/C

✨ SHINY NEW PAPER ✨ Repeated MRI measures of brain volume can help detect later conversion to AD/FTD www.sciencedirect.com/science/article/pii/S0197458025001265

✨ SHINY NEW PAPER ✨ MRI-derived regional volume and thickness are stronger predictors of cognitive decline, especially for memory, but plasma biomarkers do add predictive value www.sciencedirect.com/science/article/pii/S0197458025001137

✨ SHINY NEW PAPER ✨ WMH in the temporal lobe relate to early cortical thinning in AD, beyond what is expected due to amyloid and tau @leoriki3.bsky.social @compneurology.bsky.social www.sciencedirect.com/science/article/pii/S0197458025001216

✨ SHINY NEW PAPER ✨ BOLD in LC related to subsequent memory performance in adults across the lifespan, possibly due to attentional boosting of memory www.sciencedirect.com/science/article/pii/S019745802500123X

✨ SHINY NEW PAPER ✨ T-tau, a marker or gray matter degeneration, is more strongly correlated with synaptic biomarkers (neurogranin and BACE1) than NfL www.sciencedirect.com/science/article/pii/S0197458025001198

📚 NEW ISSUE 📚 Articles cover epigenetic and brain aging, plasma and MRI predictors of cognition in aging, aging of hippocampal microstructure, and more. www.sciencedirect.com/journal/neurobiology-of-aging/vol/155/suppl/C

✨ SHINY NEW PAPER ✨ Interactive video games that make exercise more engaging can change brain structure and function in older adults. www.sciencedirect.com/science/article/pii/S019745802500106X

✨ SHINY NEW PAPER ✨ Hearing loss is more strongly associated with tau burden than β-amyloid (Aβ) burden. @charlesmarshall.bsky.social www.sciencedirect.com/science/article/pii/S0197458025001162

📣 One more month to submit to this Special Issue on Brain Resilience & Diversity in Aging and Dementia! @mnrajah.bsky.social

✨ SHINY NEW PAPER ✨ Lifestyle risk factors can discriminate latent classes of memory trajectories but differ across racial-ethnic groups. @profrwhitmer.bsky.social www.sciencedirect.com/science/article/pii/S0197458025001174

✨ SHINY NEW PAPER ✨ A 6-month balance training intervention improves postural control and performance-related prefrontal brain activation in older adults. www.sciencedirect.com/science/article/pii/S0197458025001150

✨ SHINY NEW PAPER ✨ Hippocampal subfield volumes follow nonlinear trajectories across the lifespan. @dranadaugherty.bsky.social @noaofen.bsky.social www.sciencedirect.com/science/article/pii/S0197458025001149

✨ SHINY NEW PAPER ✨ Cortico-striatal gray matter atrophy and white matter microstructural degradation across the rhesus macaque adult lifespan. @dralisonweiss.bsky.social www.sciencedirect.com/science/article/pii/S0197458025001010

✨ SHINY NEW PAPER ✨ Sleep-disordered breathing is associated with higher Aβ burden, lower rFDG, and worse cognition in Alzheimer's Disease. @sbe.bsky.social www.sciencedirect.com/science/article/pii/S0197458025001034

50-day free share link: authors.elsevier.com/a/1lpYXivP7S... Regular link: doi.org/10.1016/j.ne... Collab with @fnim-lab.bsky.social 🧠

✨ SHINY NEW PAPER ✨ Older adults fail to gate irrelevant information, indicating a top-down inhibitory control deficit that controbutes to their worse memory. www.sciencedirect.com/science/arti... @fnim-lab.bsky.social

📚 NEW ISSUE 📚 Articles cover effects of age on brain structure, balance training, exergame interventions, links between hearing loss and AD, and more. www.sciencedirect.com/journal/neurobiology-of-aging/vol/154/suppl/C

Amazing work from @alifiyakapasi.bsky.social for her K01 @rushalzheimers.bsky.social So lucky to work with her and the rest of the team! www.sciencedirect.com/science/arti...

✨ SHINY NEW PAPER ✨ Atypical presentation of AD with greater cortical involvement is seen in individuals with younger chronological age or younger biological age relative to their chronological age. www.sciencedirect.com/science/arti... ‪@patch-lab-upenn.bsky.social‬

📚 NEW ISSUE 📚 Articles cover processing speed in background noise, biological age acceleration in Alzheimer's Disease, effects of strength training in aging, and more. www.sciencedirect.com/journal/neurobiology-of-aging/vol/153/suppl/C

✨ SHINY NEW PAPER ✨ Clusters of positive modifiable factors (physical/cognitive activity, education, sleep, depression, personality) attenuate effects of amyloid on cognition. doi.org/10.1016/j.ne...

✨ SHINY NEW PAPER ✨ Interactions between CSF misfolded proteins (Aβ, p-tau), inflammatory markers (IL-8), and brain regional CBF and atrophy are more pronounced in individuals with higher cardiovascular risk factors doi.org/10.1016/j.ne... @sylviavilleneuve.bsky.social‬

✨ SHINY NEW PAPER ✨ Higher cardiovascular disease risk in older adults may explain why shorter sleep duration relates to worse cognition. doi.org/10.1016/j.neurobiolaging.2025.04.008

Submit a paper that examine how ethnocultural diversity, social and structural determinants of health, biological sex, sociocultural gender, and intersectionality influence measures of brain resilience in aging and dementia.

📣 SPECIAL ISSUE 📣 Brain Resilience & Diversity in Aging and Dementia www.sciencedirect.com/special-issu... Due: 12/1/25 @mnrajah.bsky.social