Aging reorganizes human large-scale brain networks, with consequences for cognition & dementia risk. We’ve now mapped brain network changes over a wide range of the mouse lifespan. The changes mirror key features of human aging, but not entirely New @pnas.org paper🧵 www.pnas.org/doi/10.1073/...

This book has just been published, open access, edited by Ken Cheng and me. It contains multiple chapters originating in a wonderful Strungmann Forum held in Frankfurt around a year ago. link.springer.com/book/10.1007...

Excited to announce our new paper in Trends in Cognitive Science (TICS) on the importance of naturalistic body movements and mobile immersive virtual reality to the study of cognition! Check it out! www.sciencedirect.com/science/arti...

Is the concept of “category-selectivity” holding the field back in understanding high-level visual cortex? Detailed discussion in our published perspective piece and accompanying commentaries:

Are episodic and semantic memory really that different? Using closely matched tasks, a new study found no substantial neural differences between recalling personal experiences and general knowledge: www.nature.com/articles/s41...

This paper had a pretty shocking headline result (40% of voxels!), so I dug into it, and I think it is wrong. Essentially: they compare two noisy measures and find that about 40% of voxels have different sign between the two. I think this is just noise!

Going to SfN? We want to connect with you! Meet up with us to collaborate and share your science journey: from the questions that drive your work to the breakthroughs that inspire you. Sign up here: calendly.com/investnscien... And share with your science friends!

Memory problems will change how you see the world...literally 👀 Across two new papers, we examined the eye movement patterns of younger adults, older adults, individuals with mild cognitive impairment, and amnesic cases. 1/5

The brain represents the world around us as a series of neural states - stable patterns of activity that change as we move from one event to the next. New paper by @selmalugtmeijer.bsky.social showing that neural states get longer as people age. #PsychSciSky nature.com/articles/s42003-025-08792-4

New paper alert! 🚨 We show that age-related neural dedifferentiation in scene-selective cortex is tied to changes in eye movements. Using simultaneous fMRI + eye-tracking, we found that younger adults’ fixations covary with scene specificity, but this link weakens with age. Link in post below 👇

I'm thrilled that my first first-author paper in @fnim-lab.bsky.social is now out! We found that whole-brain cortical volume predicted the strength of neural reinstatement of scene information in the parahippocampal and medial place areas (PPA & MPA in the figure below). (1/2)

I'll admit, I was skeptical when they said Gemini was just like a bunch of PhDs. But I gotta admit they nailed it.

Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan journals.plos.org/plosbiology/...

We built the simplest possible social media platform. No algorithms. No ads. Just LLM agents posting and following. It still became a polarization machine. Then we tried six interventions to fix social media. The results were… not what we expected. arxiv.org/abs/2508.03385

In neuroscience, we often try to understand systems by analyzing their representations — using tools like regression or RSA. But are these analyses biased towards discovering a subset of what a system represents? If you're interested in this question, check out our new commentary! Thread:

Delighted to share our latest review in Nature Reviews Neuroscience! We examine the growing evidence that vascular dysfunction plays a key role in cognitive decline in ageing and dementia, and argue that preserving/restoring CBF should be central to future therapies. www.nature.com/articles/s41...

"Large language models surpass human experts in predicting neuroscience results" w @ken-lxl.bsky.social and braingpt.org. LLMs integrate a noisy yet interrelated scientific literature to forecast outcomes. nature.com/articles/s41... 1/8

We had a fascinating conversation with Dr. Louis Renoult (@renoultlouis.bsky.social) about all things memory! Here’s a preview of what we discussed and stay tuned for the full release of the episode later this week!

Apply for the opportunity to serve on JNeurosci’s Early Career Researcher Advisory Board to get more involved in scientific publishing and advocate as an early career researcher. Learn more and submit your application by July 25, 2025, 5pm ET: https://www.jneurosci.org/content/ecr-board-applications

1/11 Excited to share our @Naturestudy led by @leonooi.bsky.social @csabaorban.bsky.social @shaoshiz.bsky.social AI performance is known to scale with logarithm of sample size (Kaplan 2020), but in many domains, sample size can be # participants or # measurements... doi.org/10.1038/s415...

New press on our study linking the locus coeruleus to memory formation 🔵: newsroom.ucla.edu/releases/bra... . “…at a time when legislation promises ‘big and beautiful change,’ it turns out one of the brain’s smallest players may have the biggest impact on how we understand and remember our lives.”

JNeurosci’s Early career researcher (ECR) Advisory Board just opened a call for applications (due July 18 at 5pm ET). Join our team for a unique opportunity to serve the ECR community and advocate for ECR needs in scientific publishing: www.jneurosci.org/content/ecr-... @sfnjournals.bsky.social

🧠 Paper out! We investigated how hippocampal and cortical ripples support memory during movie watching. We found that: 🎬 Hippocampal ripples mark event boundaries 🧩 Cortical ripples predict later recall Ripples may help transform real-life experiences into lasting memories! rdcu.be/eui9l

Despite recent criticism from Quiroga to our claim that Concept Neurons emerge from Conjunctive Coding Neurons we claim: “And yet, the hippocampus codes conjunctively!”. We hope it sparks a smile (and maybe a few debates). Read here: tinyurl.com/3ycv3vj2

A very cool follow-up on one of the first studies I did with @fnim-lab.bsky.social. Older adults do not gate task-irrelevant information during episodic retrieval. New data reveal that this is not due to age differences in memory strength, but may instead reflect a decline in inhibitory control.

Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...

Drumroll... The SPM team will announce that SPM is now fully accessible from Python! 🐍 Learn more about SPM-Python at the SPM roundtable event (Friday, 1pm) and poster number 1841 at #OHBM2025. Try the beta for yourself at github.com/spm/spm-python [2/7]

New preprint & OA dataset from the lab 🥳 An open dataset of cerebral tau deposition in young healthy adults based on [18F]MK6240 positron emission tomography by Jack Lam and a terrific team of colleagues at the Neuro, Douglas and UCL ▶️ pdf doi.org/10.1101/2025... ▶️ bids osf.io/znt9d

What shapes the topography of high-level visual cortex? Excited to share a new pre-print addressing this question with connectivity-constrained interactive topographic networks, titled "Retinotopic scaffolding of high-level vision", w/ Marlene Behrmann & David Plaut. 🧵 ↓ 1/n

My latest Aronov lab paper is now published @Nature! When a chickadee looks at a distant location, the same place cells activate as if it were actually there 👁️ The hippocampus encodes where the bird is looking, AND what it expects to see next -- enabling spatial reasoning from afar bit.ly/3HvWSum

There is no binding problem because vision—and cortex more broadly—is not modular. Phrenological theories create phrenological artifacts. Beyond binding: from modular to natural vision doi.org/10.1016/j.ti... #neuroscience

Excellent podcast series let by two super talented PhD students! open.spotify.com/show/0eQPjc4...

In a recent review, @adekstreme.bsky.social and I revisit how spatial navigation breaks down in aging and early Alzheimer’s disease - and why it’s not just about the brain. doi.org/10.1016/j.co... #SpatialNavigation #AgingBrain #EmbodiedCognition #AlzheimerResearch

🧠✨How do we rebuild our memories? In our new study, we show that hippocampal ripples kickstart a coordinated expansion of cortical activity that helps reconstruct past experiences. We recorded iEEG from patients during memory retrieval... and found something really cool 👇(thread)

It is a great pleasure to share this new collaborative work on the Cognitive Neuroscience of Memory Representations with @fnim-lab.bsky.social @cvlneuro.bsky.social @psychologyuea.bsky.social osf.io/preprints/ps...

New episode alert! 🎙️ We're kicking things off on our new Neuro Logic podcast account by sharing that we have a new episode featuring Dr. Marson on Declining Financial Capacity in Cognitive Aging and Dementia. Listen now: open.spotify.com/episode/5I2v... #NeuroLogic #podcast #CVL #UTD

It is important now more than ever for scientists to share their work with the general public. I am pleased to have contributed to investNScience’s campaign which they are currently running across numerous social media platforms. It is a great initiative that makes science more relevant to everyone.

Autonomic dysfunction in neurodegenerative disease — a Review by Mara Mather www.nature.com/articles/s41... @maramather.bsky.social #neuroscience

Are you attending #CNS2025 ? If so, then you should stop by my poster on Tuesday morning for a fun chat about fmri and spatial memory!!

It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠

🚨 New lab paper!🚨 A dream study of mine for nearly 20 yrs not possible until now thanks to NIH 🧠 funding & 1st-author lead @seeber.bsky.social We tracked hippocampal activity as people walked memory-guided paths & imagined them again. Did brain patterns reappear?🧵👇 www.nature.com/articles/s41...

Tired but happy to say this is out w @andreaeyleen.bsky.social: Are Neurocognitive Representations 'Small Cakes'? philsci-archive.pitt.edu/24834/ We analyse cog neuro theories showing how vicious regress, e.g. the homunculus fallacy, is (sadly) alive and well — and importantly how to avoid it. 1/

A lack of programming experience can derail experimental aspirations. Andrew Jahn shares how new educational tools that broaden both access and ease of use for neuroimaging are helping researchers fulfill their experimental ambitions. By Andrew Jahn www.thetransmitter.org/future-of-fm...

Many neuroscience students are steeped in an experiment-first style of thinking that leads to “random walk science.” Let’s not forget how theory can guide experiments towards deeper insights, writes @gershbrain.bsky.social. #neuroskyence www.thetransmitter.org/theoretical-...

HOT OFF THE PRESS - Back in 2019 we started asking ourselves what could you to demonstrate where werable, OPM-MEG technology could fit into naturalistic #neuroskyence. One snag, we'd have to build the system from scratch first... Anyway its 2025, read the paper here -> doi.org/10.1162/imag...

Pretty soon its going to be easier to keep a list of the brain areas that don't encode a cognitive map. www.nature.com/articles/s42...

Very proud of @josholivier.bsky.social (lab manager at @fnim-lab.bsky.social) for getting his first *first-author* preprint out! ✨😄

New paper in Imaging Neuroscience by Saana M. Korkki, Alireza Salami, et al: Dedifferentiation of caudate functional organization is linked to reduced D1 dopamine receptor availability and poorer memory function in aging doi.org/10.1162/imag...

Grid cells have a geometry in time. Thanks to @azvollan.bsky.social l & @rjgardner.bsky.social for this heroic discovery. @ercresearch.bsky.social #KiloNeurons @m-bmoser.bsky.social @kavlintnu.bsky.social @nature.com @kavlifoundation.bsky.social www.nature.com/articles/s41...