Amin Saberi
@amnsbr.bsky.social
📤 143
📥 248
📝 20
Postdoc, Neurobiosocial Group at MPI-CBS & FZJ-INM7 | MD aminsaberi.me
reposted by
Amin Saberi
Golia Shafiei
9 days ago
Excited to share that our work introducing the Reproducible Brain Charts (RBC) data resource is now published in Neuron!! 🎉 📚 Read the paper:
authors.elsevier.com/c/1lpaF3BtfH...
🧠 Explore the RBC dataset:
reprobrainchart.github.io
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Amin Saberi
Bratislav Misic
21 days ago
The effect of spherical projections on spin tests for brain maps |
doi.org/10.1162/IMAG...
Spin tests are the de facto null model for map-to-map comparisons in brain imaging. Why don't they perfectly control false positives? @vincebaz.bsky.social explores ⤵️
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Amin Saberi
Alessandro Gozzi
21 days ago
🚨 Excited to share the latest preprint form the lab ➡️https://tinyurl.com/32d3be9f Here we tackle a long-standing chicken-or-egg 🐣🥚question in
#autism
and developmental neuroscience ➡️ Is excitation–inhibition (E:I) imbalance a "cause" or a "consequence" of
#autism
? Check out what we found! 🧵1/n
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Amin Saberi
Bratislav Misic
about 2 months ago
Integrating and interpreting brain maps |
doi.org/10.1016/j.ti...
Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️
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Amin Saberi
Sofie Valk
3 months ago
My lab is at
@ohbmofficial.bsky.social
in Brisbane! Find us at the
@gradientsworkshop.bsky.social
- great talks by
@wanb.bsky.social
Katerina Manoli (and others) Then we are at the educational sessions where
@claraweber.bsky.social
will present
@amnsbr.bsky.social
work on E/I balance.
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Amin Saberi
Sofie Valk
4 months ago
Very happy about this paper and what we learned from it!! Please see Amins thread for more juice 🧃 and let us know if you are also on the E/I journey and like to try our toolbox
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Amin Saberi
Leon Lotter
4 months ago
Amazing new paper on individual development of E/I balance during adolescence, first-authored by
@amnsbr.bsky.social
! Read @ Science Advances:
www.science.org/doi/10.1126/...
Bonus: Amin developed a tool to run biophysical network modelling on GPUs – because why shouldn't he?
cubnm.readthedocs.io
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Amin Saberi
Rick Betzel
4 months ago
This is awesome!
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Amin Saberi
Boris Bernhardt
4 months ago
⭐ new paper Maturation of cortical excitation-inhibition (EI) in adolescence now in Science Advances 💥 A true tour de force of multimodal MRI, connectomics & GPU-powered 🤖!! biophysical modelling by hiball superheroes 🦸♂️🦸♀️🦸♂️
@amnsbr.bsky.social
@sofievalk.bsky.social
@sbe.bsky.social
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🧠⚖️📉 How does the cortical excitation-inhibition ratio mature during adolescence? We asked this in our new paper just out in
#ScienceAdvances
✨ “Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling” 📄
www.science.org/doi/full/10....
🧵⤵️
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Adolescent maturation of cortical excitation-inhibition ratio based on individualized biophysical network modeling
Individualized simulations reveal a decrease in excitation-inhibition ratio in association areas throughout adolescence.
https://www.science.org/doi/full/10.1126/sciadv.adr8164
4 months ago
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reposted by
Amin Saberi
Sofie Valk
4 months ago
We are seeking a scientific coordinator for my research group at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig 😊🧠🌈 Could be ideal for a gap year between MSc and PhD or PhD and postdoc! Please out more here:
recruitingapp-5218.de.umantis.com/Vacancies/43...
?
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Scientific Coordinator (m/f/d) Part-time (50%) | Karriereportal Max-Planck-Institut für Kognitions- und Neurowissenschaften
Scientific Coordinator (m/f/d) Part-time (50%) | Karriereportal Max-Planck-Institut für Kognitions- und Neurowissenschaften
https://recruitingapp-5218.de.umantis.com/Vacancies/431/Description/2/Default
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Amin Saberi
Boris Bernhardt
5 months ago
⭐ preprint ⭐ In-vivo evidence for increased tau deposition in temporal lobe epilepsy ➡️ Using [¹⁸F]MK-6240 PET, we show increased tau in young and middle aged TLE ➡️ Tau aggregation potential mechanism of disease progression & cognitive decline ➡️ pdf
bit.ly/4mmlTYH
by Raul Cruces & a super team
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reposted by
Amin Saberi
5 months ago
The gradients workshop is happening soon! Please join us on June 23rd in Brisbane for a full day of gradient fun! 🌈 ✅ Amazing speaker line up ✅ Poster presentation ✅ Flash talks for selected abstracts Deets on program, abstract submission, and registration 👉
gradients-workshop.github.io
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Gradients of Brain Organisation, Brisbane 2025
GRADIENTS WORKSHOP
https://gradients-workshop.github.io/
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Amin Saberi
Simon Eickhoff
5 months ago
Our
#metaanalysis
(n = 231) in JAMAPsych reveals consistent brain abnormalities across
#sleep
disorders involving affective and cognitive hubs in sgACC, amygdala/hippocampus Short-term sleep deprivation shows a distinct picture, affecting the thalamus
jamanetwork.com/journals/jam...
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Amin Saberi
Boris Bernhardt
5 months ago
in press
@natcomms.nature.com
🌟 "Multimodal gradients unify local and global cortical organization" 7T MRI + cytoarchitectonics reveal a sensory-paralimbic axis of areal specialization & integration led by superstar Yezhou Wang & a terrific team of friends & colleagues ▶️
doi.org/10.1038/s414...
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Amin Saberi
Ke Xie
5 months ago
✨ What makes the brain's functional organization different in each
#TLE
patient? 🧠 ✨ We used a large sample (298 healthy adults, 282 TLE, 45 disease controls) + normative modeling to capture individualized functional disruptions. 🔎
#epilepsy
#neuroimaging
#precisionmedicine
doi.org/10.1101/2025...
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Personalized Biomarkers of Multiscale Functional Alterations in Temporal Lobe Epilepsy
Temporal lobe epilepsy (TLE) presents with substantial inter-patient variability in clinical and neuroimaging manifestations. This multicenter study examined inter-individual differences in spatial pa...
https://doi.org/10.1101/2025.04.24.650457
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Amin Saberi
Mashbayar Tugsbayar
6 months ago
Top-down feedback is ubiquitous in the brain and computationally distinct, but rarely modeled in deep neural networks. What happens when a DNN has biologically-inspired top-down feedback? 🧠📈 Our new paper explores this:
elifesciences.org/reviewed-pre...
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Top-down feedback matters: Functional impact of brainlike connectivity motifs on audiovisual integration
https://elifesciences.org/reviewed-preprints/105953
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Amin Saberi
Thomas Yeo
6 months ago
While the world burns, we cook up a new preprint!
doi.org/10.1101/2025...
Biophysical modeling is a key tool to derive mechanistic insights into the brain. These models are governed by biologically meaningful parameters (unlike artificial neural networks), but the dirty secret ... 1/N
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Amin Saberi
Giacomo Bignardi
6 months ago
Our study is now out in
@naturecomms.bsky.social
! Here, we integrate large-scale registry musicality data from twins to investigate the genetics of music enjoyment 🧬🎶🧑🤝🧑
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Amin Saberi
Donna Gift Cabalo
6 months ago
Our open-source multimodal precision MRI dataset is officially out! 🧲🧠🧲
www.nature.com/articles/s41...
osf.io/mhq3f/
@borismontreal.bsky.social
@jroyer.bsky.social
@themindwanders.bsky.social
@jordandekraker.bsky.social
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Multimodal precision MRI of the individual human brain at ultra-high fields - Scientific Data
Scientific Data - Multimodal precision MRI of the individual human brain at ultra-high fields
https://www.nature.com/articles/s41597-025-04863-7?utm_source=rct_congratemailt&utm_medium=email&utm_campaign=oa_20250329&utm_content=10.1038/s41597-025-04863-7
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Amin Saberi
Shahab Bakhtiari
7 months ago
📢 We have a new
#NeuroAI
postdoctoral position in the lab! If you have a strong background in
#NeuroAI
or computational neuroscience, I’d love to hear from you. (Repost please) 🧠📈🤖
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Amin Saberi
Sofie Valk
7 months ago
Brain function fluctuates daily—but what drives these changes?
direct.mit.edu/imag/article...
super proud of Deniz Yilmaz and Bianca Serio and thankful for the open data of
@emilyjacobs.bsky.social
and Laura Pritschet 🌈👫 studying hormonal fluctuations in functional gradients ❤️🔥
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https://direct.mit.edu/imag/article/doi/10.1162/imag_a_00474/127768
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Amin Saberi
Bratislav Misic
8 months ago
Synaptome architecture shapes regional dynamics in the mouse brain |
www.biorxiv.org/content/10.1...
Led by Justine Hansen Big news: there are all sorts of different synapse types in the brain 👀‼️⤵️
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Amin Saberi
Shervin Safavi
7 months ago
Re-posting is appreciated: We have a fully funded PhD position in CMC lab
@cmc-lab.bsky.social
(at @tudresden_de). You can use
forms.gle/qiAv5NZ871kv...
to send your application and find more information. Deadline is April 30. Find more about CMC lab:
cmclab.org
and email me if you have questions.
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https://forms.gle/qiAv5NZ871kvQ1u96
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Amin Saberi
Alexandra John
8 months ago
For all the thalamus lovers❤️🔥 : Excited to share that our Paper is out now✨Huge thanks to
@sofievalk.bsky.social
and all collaborators
@meikehettwer.bsky.social
,
@wanb.bsky.social
,
@amnsbr.bsky.social
,
@jroyer.bsky.social
,
@borismontreal.bsky.social
,
@linaschaare.bsky.social
, Seyma Bayrak
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Amin Saberi
James Pang
8 months ago
For my first-ever bluesky post, I'm really excited to share our new preprint "Geometric influences on the regional organization of the mammalian brain" with
@alexfornito.bsky.social
and a superstar 17-person team! (1/n)
www.biorxiv.org/content/10.1...
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Geometric influences on the regional organization of the mammalian brain
The mammalian brain is comprised of anatomically and functionally distinct regions. Substantial work over the past century has pursued the generation of ever-more accurate maps of regional boundaries,...
https://www.biorxiv.org/content/10.1101/2025.01.30.635820v1
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Amin Saberi
Rick Betzel
10 months ago
A few words on the preprint! 1/
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Amin Saberi
Patrick Mineault
10 months ago
There's so many ML tools coming out that purport to increase your productivity, but what should you actually pay attention to? Here's my roundup
www.neuroai.science/p/ml-tools-f...
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ML tools for neuroscientists
Which tools should you be using?
https://www.neuroai.science/p/ml-tools-for-neuroscientists
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Amin Saberi
Simon Eickhoff
10 months ago
The limiting factor for MRI based prediction of behavioral traits may be neither the imaging nor the pipeline or learning algorith but rather the reliability of the target phenotypes Thought provoking work my Martin Gell et al:
www.nature.com/articles/s41...
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How measurement noise limits the accuracy of brain-behaviour predictions - Nature Communications
Our ability to identify associations between behaviour and brain imaging is important for uncovering markers of cognition and disease. Here, the authors illustrate the importance of the reliability of...
https://www.nature.com/articles/s41467-024-54022-6
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Amin Saberi
Bin Wan
10 months ago
Thrilled to share my latest work "Microstructural asymmetry in the human cortex" now out in NatComms.
www.nature.com/articles/s41...
This work used cytoarchitecture (BigBrain), T1w/T2w, qT1, and MT measures to bring the cortical asymmetry from macrostructure to microstructure.
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Microstructural asymmetry in the human cortex - Nature Communications
The human cortex displays an anterior-to-posterior asymmetry, identified via both post-mortem and in vivo microstructural measurements. Microstructural asymmetry is heritable, varies across cortical l...
https://www.nature.com/articles/s41467-024-54243-9
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Amin Saberi
Sofie Valk
10 months ago
rdcu.be/d07ia
here we should how hemispheric asymmetry in the human cortex is rooted in microstructure. 🙏 Bin Wan,
@amnsbr.bsky.social
@sbe.bsky.social
@borismontreal.bsky.social
and all others not yet in Bluesky 💜
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Microstructural asymmetry in the human cortex
Nature Communications - The human cortex displays an anterior-to-posterior asymmetry, identified via both post-mortem and in vivo microstructural measurements. Microstructural asymmetry is...
https://rdcu.be/d07ia
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Amin Saberi
DrBreaky
11 months ago
The brain expresses activity in complex patterns, reflecting the influence of cytoarchitectural, biochemical & genetic properties. Eigenstrapping is our method for inferring the similarity between two such brain maps while excluding spurious (chance) relationships
www.biorxiv.org/content/10.1...
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Amin Saberi
Sofie Valk
11 months ago
A website update on what neuro - bio - social then means in terms of what we do and plan to do:
www.cbs.mpg.de/independent-...
💜🧠✨NBS galore (next to remaining cognitive neurogenetics RGL at Research Center Jülich 💙)
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https://www.cbs.mpg.de/independent-research-groups/neurobiosocial?TSPD_101_R0=08fcbcb3fdab2000014c900a4890df4be2c6098b7c64b9b613c3f738e1bc0cd0880b422e31a47eec08997c2db414300065951aff21d2e8eeb9a9ad6ec3cad7c0d2f6e5e43523e1ad7bb2295b5cf21d05946cf57204c20b9b4d3b08402a506dd6
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Amin Saberi
Sofie Valk
almost 2 years ago
The human #cortex consists of layers with unique properties. @amnsbr @sofievalk &co show that regional variation of laminar thickness profiles in human #isocortex is associated with the cortical #connectome & hierarchical organization #PLOSBiology
plos.io/3QW7WDm
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The regional variation of laminar thickness in the human isocortex is related to cortical hierarchy ...
The human isocortex consists of tangentially organized layers with unique cytoarchitectural properties. This study shows that the regional variation of high-resolution histology-based laminar thicknes...
https://plos.io/3QW7WDm
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