@randolab.bsky.social
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I am excited to share a lab publication, led by former postdoctoral fellows Daniel Benjamin and Jengmin Kang, examining how quiescent stem cells allocate resources for survival over function during aging and revealing a survivorship bias in the study of cell aging.
www.science.org/doi/10.1126/...
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Cellular survivorship bias as a mechanistic driver of muscle stem cell aging
Aging is characterized by a decline in the ability of tissue repair and regeneration after injury. In skeletal muscle, this decline is largely driven by impaired function of muscle stem cells (MuSCs) ...
https://www.science.org/doi/10.1126/science.ads9175
10 days ago
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reposted by
Cell Press Events
7 months ago
We’re delighted to welcome Future Science Prize 2024 winner Hongkui Deng @pku1898.bsky.social to the speaker lineup at the upcoming @CellSymposia #CSStemCells2025. Submit an abstract for a chance to join him in LA in November!
http://dlvr.it/TLn6XX
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This study represents the next stage of organoid development, incorporating vascularization.
#stemcellresearch
#regenerativemedicine
add a skeleton here at some point
7 months ago
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Happy to share our review at Cell Stem Cell as part of their Hallmarks series. As always, a pleasure to work with friends and colleagues Anne Brunet (
@brunetlab.bsky.social
) and Peggy Goodell(
@goodell-lab.bsky.social
). Hallmarks of stem cell aging: Cell Stem Cell
www.cell.com/cell-stem-ce...
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Hallmarks of stem cell aging
Aging disrupts core functions of somatic stem cells throughout the body, leading to impaired tissue maintenance and repair. We identify five key features of aged stem cells, highlighting how their dys...
https://www.cell.com/cell-stem-cell/fulltext/S1934-5909%2825%2900226-7
8 months ago
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reposted by
UCLA Broad Stem Cell Research Center
9 months ago
UCLA’s Translational Cell Therapy Lab partners with stem cell researchers to build life-changing therapies — all while mentoring the next generation scientists who’ll carry this critical work forward. 🧬 Read more:
ucla.in/45kYAbz
#CellTherapy
#RegenerativeMedicine
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A new twist for SSRIs - potential role as adjuncts for cancer therapy thanks to the pioneering work of Dr. Lili Yang.
add a skeleton here at some point
9 months ago
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Another life-saving treatment from Dr. Donald Kohn's group at UCLA and collaborators. Congratulations to the incredible team of investigators. Another milestone for the miracles of cell and gene therapy.
add a skeleton here at some point
10 months ago
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I am excited to share a recent publication from the lab, spearheaded by senior scientist Di Wu, using a bioinstructive nanocapsules to orchestrate the temporal delivery of growth factors in order to promote stem cell-mediated tissue engineering in vivo.
www.nature.com/articles/s41...
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Bioinstructive scaffolds enhance stem cell engraftment for functional tissue regeneration - Nature Materials
A decellularized extracellular matrix scaffold containing nanocapsules orchestrates timed growth factor release to promote muscle stem cell proliferation and differentiation and effective muscle regen...
https://www.nature.com/articles/s41563-025-02212-y
10 months ago
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