A family of small proteins links c-di-GMP riboswitch signaling with sporulation in Clostridioides difficile https://www.biorxiv.org/content/10.64898/2026.06.10.731418v1

New pre-print from the lab! Murepavedin is a Pseudomonas-specific antibiotic, but it disrupts the outer membranes of a wide range of different Gram-negatives. www.biorxiv.org/content/10.6...

I am very happy to be in the part of this work! Congratulations @abarbotin.bsky.social @carballido-lab.bsky.social journals.asm.org/doi/10.1128/...

D-alanine aminotransferase (Dat) promotes Staphylococcus aureus colonization fitness on human nasal respiratory epithelium https://www.biorxiv.org/content/10.64898/2026.06.01.729472v1

Decoding the interactome for cyclic-di-AMP-producing enzyme diadenylate cyclase -in #mSystems journals.asm.org/doi/10.1128/...

Latest research from the lab out now. We examined the role and expression of fimbriae during UPEC bloodstream infection. A real team effort and brilliant collaboration with Mark Schembri’s lab in Brisbane. Thanks to the MRC and BBSRC for supporting our research @ukri.org

I'm very happy to share that part of my PhD research has published in PLOS Genetics! « FabF and FadM cooperate to recycle fatty acids and rescue ΔplsX lethality in Staphylococcus aureus. » 🥰 Many thanks to all collaborators. journals.plos.org/plosgenetics...

Out Now! Wall teichoic acids regulate peptidoglycan synthesis to maintain rod shape in Bacillus subtilis #MicroSky

Purine and pyrimidine analogues differentially regulate cell wall precursor biosynthesis to control β-lactam susceptibility in methicillin resistant Staphylococcus aureus https://www.biorxiv.org/content/10.64898/2026.05.24.727567v1

E. coli ST131 is becoming carbapenem resistant. I suspect as CTX-M moves onto the chromosome and the F plasmid is lost facilitating acquisition of carbapenemase plasmids. No good can come of this

We have a PhD position in Leiden within our #ERCSyG @microclockerc.bsky.social project to dissect circadian clocks in bacterial biofilms We are looking for candidates with optogenetics, single cell microscopy and image analysis background Application deadline 12 June 2026 👉 edu.nl/cqra3

I'm currently advertising a PhD position in my lab, to study the transition from commensal to pathogen in Staphylococcus aureus. Details available here, please share! www.keele.ac.uk/research/pos...

Super excited to share the final version of our story on how Enterococcus faecalis remodels membrane lipids to protect itself from daptomycin! 🥳 www.pnas.org/doi/10.1073/...

A new weapon against stubborn bacteria: study shows that disrupting two cell-wall pathways at once can overload bacterial metabolism, causing oxidative damage and cell death – even in wall-free L-forms that evade many antibiotics. Via Sydney Mass Spectrometry CRF. Paper 👉 go.nature.com/4tgbBeV

Any postdocs in Microscopy/Microbiology/Host-Pathogen/AMR looking to set up their own labs? Look here: www.uts.edu.au/research/exp... Life in Sydney is pretty darn good! ☀️🏄🏻‍♂️🦘 Reach out for more info.

Adaptation of the freshwater anaerobic methanotroph 'Ca. Methanoperedens vercellensis' to low pH levels reveals membrane lipid remodelling https://www.biorxiv.org/content/10.64898/2026.04.11.717812v1

Big congratulations !🥰🥳

Rut named fellow of the European Academy of Microbiology (EAM)!!! fems-microbiology.org/european-aca...

The fatty acid synthesis pathway is a checkpoint for lipoteichoic acid synthesis in Staphylococcus aureus https://www.biorxiv.org/content/10.64898/2026.04.06.715823v1

Two temperature-dependent membrane fluidity regimes in Gram-positive bacteria https://www.biorxiv.org/content/10.64898/2026.01.22.701129v1

E. coli is the leading bacterium causing death from AMR infections worldwide. If you'd like to explore approaches to exploit the DNA damage response as alternative antimicrobial, please apply to the following PhD studentship available in my lab starting October 2026: www.findaphd.com/phds/project...

MPKaDB: A pKa Database for Exploring pH Dependence in Membrane Proteins https://www.biorxiv.org/content/10.1101/2025.11.14.688495v1

A two-component system signaling hub controls enterococcal membrane remodeling in response to daptomycin https://www.biorxiv.org/content/10.1101/2025.11.16.688641v1

BioPrediction-PPI: Simplifying the Prediction of Protein-Protein Interactions through Artificial Intelligence https://www.biorxiv.org/content/10.1101/2025.11.16.688401v1

🔊 New story! This GlmR (of hope) article has it all. Cell shape, cytokinesis, c-di-AMP, and catalysis - the famous 4 Cs 💎? There is also antibiotic resistance, phosphorylation, acetylation, and a (cool) model to explain what shapes Bacillus cells. Excellent group effort. Congrats team! #Microsky

Recruitment of the outer-membrane lipoprotein DolP to thedivision site via cardiolipin-mediated diffusion-stateswitching https://www.biorxiv.org/content/10.1101/2025.10.29.685289v1

Excited to share my latest postdoctoral work in the Shen Lab at Tufts! In this study, we follow up on an exciting finding by former grad student @shailab.bsky.social that C diff uses its Class A PBP (PBP1) to drive cell division (unlike previously studied bacteria)! journals.plos.org/plosgenetics...

📢 We have an open position for a postdoc to join my lab. It's a great position @animecol-uu.bsky.social, fully salaried for 2.5 years with all benefits. www.uu.se/en/about-uu/... The project is about transmission patterns of bacteria and antimicrobial resistance (AMR) in aquatic insects. 🧬🦠 (1/3)

#MicrobiologyMonday: Staphylococcus aureus divides by building a septum and then splitting into 2 daughter cells. But how is septum formation coordinated with cell scission? Research in #mBio suggests cell wall mechanical stress could play a role: asm.social/2Eq

Identification of radical SAM enzymes responsible for the methylation and desaturation of archaeal lipids and an AttH hydratase mediating hydroxy-GDGT biosynthesis https://www.biorxiv.org/content/10.1101/2025.10.20.683597v1

Chromosome replication and cell division cycles are not synchronized in Staphylococcus aureus, with cells exhibiting two segregated origins of replication at the start of the cell cycle #bacteria #microbiology

🦠🔬🤖🧑‍💻 #mAIcrobe is out! With @pinholab.bsky.social's lab, we launched an open-source framework for high-throughput bacterial image analysis. By rockstars A. Brito & B. Saraiva et al, making #DeepLearning for phenotyping accessible! Easy to use, plus model training 📜 www.biorxiv.org/content/10.1...

PhD project available in my lab. Email me with CV if interested www.findaphd.com/phds/project... #microsky #bioimaging

We’re excited to announce the incredible speaker line-up for the Prokaryotic Cell Biology Conference! Join the leading researchers as they explore the latest advances in Nanoimaging, Cell Growth and Cellular Structures. Join our speakers & register today! ➡️https://bit.ly/47rtkbw #ProkaryoticCellBio

Peptidoglycan recycling is critical for cell division, cell wall integrity and β-lactam resistance in Caulobacter crescentus https://www.biorxiv.org/content/10.1101/2025.10.15.682734v1

Structural basis for MurJ inhibition by phage lysis protein SglPP7 suggesting convergence https://www.biorxiv.org/content/10.1101/2025.10.15.682725v1

The outer membrane of Gram-negative bacteria blocks many antibiotics. Our latest work reveals that L-type pyocins bypass this barrier by inactivating the BAM complex, killing Pseudomonas aeruginosa without entering the cell, providing a new blueprint for beating antibiotic resistance.

Also see the accompanying paper from Carol Gross' lab that used a similar approach for Bacillus subtilis: www.cell.com/cell-systems...

#Perspective Estrela and Huang discuss nutrient starvation in the context of the gut microbiome, outlining what is known and highlighting key questions for future research to address knowledge gaps. #MicroSky #MicrobiomeSky 🦠 www.nature.com/articles/s41...

Peptidoglycan remodelling improves salt resilience of Zymomonas mobilis https://www.biorxiv.org/content/10.1101/2025.10.04.680478v1

BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance" Stay tuned for more. #NobelPrize

Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org! It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance. Huge congrats to Wendy & colleagues! shorturl.at/WbFQC

Architecture of a peptidoglycan peptidase complex involved in morphological transition in Helicobacter pylori. https://www.biorxiv.org/content/10.1101/2025.08.29.672660v1

Uropathogenic #Ecoli #UPEC proliferate as round coccoid cells during intracellular infection; @alaskapokhrel.bsky.social @bill-lab.bsky.social &co show that accelerated division via FtsZ constriction drives this, the coccobacillus form persisting for generations @plosbiology.org 🧪 plos.io/4gdx97i

Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to @isabellalin.bsky.social who left for grad school this week and her mentor @cassidyprints.bsky.social! www.biorxiv.org/content/10.1...

My MCDB dept is accepting applications for a faculty position at the Assistant Professor level! Applications Due by October 15, 2025 We welcome applications from all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal levels. lsa.umich.edu/mcdb/news-ev...

Happy to share Iván’s first-author pub from the lab! www.cell.com/cell-reports...

Good opportunity here to work with a super talented new PI.

"What makes S. aureus such a difficult vaccination candidate?" Here are some answers:

Engineering non-exponential proliferation in Escherichia coli using functionalized protein aggregates https://www.biorxiv.org/content/10.1101/2025.08.23.671898v1