The rise of ‘nightmare bacteria’: antimicrobial resistance in five charts www.nature.com/articles/d41...

We're just 6 months away from @keystoneSymposia.bsky.social Beyond #Antibiotics : Emerging Strategies Combating #BacterialInfection, May 2026 in Breckenridge! 👉Scholarship and short talk abstract deadlines are Jan 7! 🧐 keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26

ournals.asm.org/doi/10.1128/spectrum.02278-25?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed Pleased to present our latest work from Doctoral candidate Camryn Bonn. Emergence of S. aureus strains with increased resistance to antimicrobial fatty acids.

Our new paper on type VII - showing a role in delaying macrophage death-

🏥 Die geplante #Krankenhausreform gefährdet die infektionsmedizinische Versorgung. In einer gemeinsamen Stellungnahme fordern zahlreiche Fachgesellschaften und Verbände die Wiederaufnahme der Leistungsgruppe „Klinische Infektiologie“, um die Versorgungsqualität und Patientensicherheit zu sichern.

Delighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better www.nature.com/articles/s41...

and Staphylococcus story in this paper.... www.microbiologyresearch.org/content/jour... All dependent on friends in @universityofhull.bsky.social Michelle Rudden, Holly Wilkinson and Matt Hardman & co., & Unilever colleagues Barry Murphy, Jo Hunt & Rob Cornmell & Yorkies @seanmeaden.bsky.social

DZIF Start-up Fund: Support for spin-offs in infection research with mentoring + up to €500K funding. Focus: preventive & therapeutic anti-infectives. Apply by Nov 30, 2025! More info ➡️

Check it out! A proper team effort from past and present group members and a great collaboration with @sergemostowylab.bsky.social

Happy to share this new article online at #mSphere journals.asm.org/doi/10.1128/... Human nasal organoids (HNOs) are a new model system for studying bacterial colonization and interspecies interactions. A big congratulations to the whole team, especially co-first authors: Andrea Boyd and Leah Kafer

#ResearchCareers: Just finishing your #PhD and wondering if the DFG’s Walter Benjamin Programme is a #funding option for your next step in academia? Come and find out in our digital info talk on 14 October. No registration, the meeting link will be published here: ➡️ www.dfg.de/en/research-...

Our work deciphering the substrate preferences of a di-/tripeptide transporter from S. aureus is now available as a proof at @plos.org Pathogens! Big thanks to the reviewers and to all the brilliant co-authors, particularly Callum who helped get those last few crucial experiments across the line

Congratulations @lisamaierlab.bsky.social and Anne, much deserved. You are also such an asset for @cmfi.bsky.social and @dzif.bsky.social

CDC reports that the 'nightmare bacteria' with the NDM gene infections rose ~ 70% from 2019–2023 & is resistant to almost all antibiotics. At GARDP, Shionogi’s approved antibiotic cefiderocol & Bugworks’ BWC0977, now in clinical development, show activity against it. 🔗Read: bit.ly/4pFG05H

Fascinating study delineating plasmid evolution during the last 100 years.

Latest from Lizzie Ledger in the lab…. Very cool story demonstrating the cross reactivity of a single AMR mechanism to confer resistance/tolerance to two distinct classes of antibiotics. journals.asm.org/doi/10.1128/...

#NewResearch Nasal colonisation by S. aureus is linked with depression in a human cohort and shown in a mouse model to cause decreased serotonin and dopamine in the brain #MicroSky #Depression www.nature.com/articles/s41...

How much of selection in human microbiomes is driven by phage? Excited to share our latest, led by A. Delphine Tripp, showing a case where phage is just not that important: Phage-mediated lysis does not determine Cutibacterium acnes colonization on human skin www.biorxiv.org/content/10.1... 🧵

CRISPR-Cas9 enables efficient genome engineering of the strictly lytic, broad-host-range staphylococcal bacteriophage K | Applied and Environmental Microbiology journals.asm.org/doi/10.1128/...

📃 New paper alert! The Zychlinsky Lab and @raunser-lab.bsky.social identified the first protein that converts chromatin into an immune effector: Myeloperoxidase transforms chromatin into neutrophil extracellular traps. Now published in @nature.com: www.nature.com/articles/s41...

Dynamic visualization of extracellular matrix components in S. aureus colony biofilms reveals functional amyloids leading to the formation of cap-like structures @biofilmjournal.bsky.social from Agneta Richter-Dahlfors www.sciencedirect.com/science/arti...

Congratulations @kengmo.bsky.social !

I am happy to announce publication of our new perspectives paper on applying evolutionary theory to host-microbiome evolution - new tricks for old dogs! @bweek.bsky.social @uni-kiel.de @transevo.bsky.social @crc1182.bsky.social www.nature.com/articles/s41...

Who should pay for #AMR innovation? www.sciencedirect.com/science/arti... @akesselheim.bsky.social

New work from the lab, lead by Nathan Palk and supported by Tarcisio Brignoli and Marcia Boura…. None of which are on here! If you like S. aureus, toxin production and two component regulatory systems, you’ll like this: www.microbiologyresearch.org/content/jour...

Interesting info on BlueSky accounts bluefacts.app

Join us at the VAAM Annual Conference🌟 22.-25.3.2026 in Berlin 👥! ✏️Registration is now open - benefit from early bird fees🏃‍♀️! 📝 Submit your abstract & 🎓 Apply for student travel grants until 🗓️ 7 November 2025. All details & more info 👉https://t1p.de/zazfv

How do keratinocytes sense bacterial commensals or pathogens? @cmfi.bsky.social Here is our recent review: www.sciencedirect.com/science/arti...

New preprint from the lab, in collaboration with Ed Tate, Nate Traaseth and many others! www.biorxiv.org/content/10.1...

Our new review “𝘛𝘩𝘦 𝘊𝘦𝘯𝘵𝘳𝘢𝘭 𝘐𝘮𝘱𝘰𝘳𝘵𝘢𝘯𝘤𝘦 𝘰𝘧 𝘝𝘢𝘤𝘤𝘪𝘯𝘦𝘴 𝘵𝘰 𝘔𝘪𝘵𝘪𝘨𝘢𝘵𝘦 𝘵𝘩𝘦 𝘛𝘩𝘳𝘦𝘢𝘵 𝘰𝘧 𝘈𝘯𝘵𝘪𝘣𝘪𝘰𝘵𝘪𝘤-𝘙𝘦𝘴𝘪𝘴𝘵𝘢𝘯𝘵 𝘉𝘢𝘤𝘵𝘦𝘳𝘪𝘢𝘭 𝘗𝘢𝘵𝘩𝘰𝘨𝘦𝘯𝘴” is out Compared to antibiotics, vaccines: ✓ Act prophylactically at low pathogen burden ✓ Less prone to inducing resistance due to multifactorial nature of immune pressure 🧵1/3

"What makes S. aureus such a difficult vaccination candidate?" Here are some answers:

New online! Methicillin-resistant and susceptible Staphylococcus aureus: tolerance, immune evasion and treatment

Great work from @kdc509.bsky.social that we had a sneak peak of at the Staph GRC. Coming from a Gram -ve background, its funny that Staph don't use polyamines at all, in fact have to evolve resistance mechanisms to host produced ones....

Preprint: Xin Du, Ching-Wen Tseng George Liu Lab @UCSanDiego Vaccine testing typically uses young healthy mice But 𝘚𝘵𝘢𝘱𝘩𝘺𝘭𝘰𝘤𝘰𝘤𝘤𝘶𝘴 𝘢𝘶𝘳𝘦𝘶𝘴 α-toxin (Hla) loses cytolytic and proinflammatory potency in murine and human neutrophils of aged individuals due to reduced ADAM10 receptor activity 🧵1/2

@shetoot.bsky.social @isamirgiri.bsky.social

Super high MRSA and VISA rates in Gaza. Multidrug-resistant bacteria amid health-system collapse in Gaza - The Lancet Infectious Diseases www.thelancet.com/journals/lan...

New role for Dectin 1 in Staphylococcus infections www.nature.com/articles/s42...

💊 DZIF funding of €2.2 million supports the development of a groundbreaking living biotherapeutic to combat pathogenic bacteria in the gut @helmholtzhzi.bsky.social

We found a new #bacteriocin family that forms large pores using transmembrane helices! #MicroSky #antimicrobialpeptide #RiPP rdcu.be/ezuY1

Happy to share Iván’s first-author pub from the lab! www.cell.com/cell-reports...

📢 #CallforApplications: Are you conducting translational infection research in Germany? The DZIF Academy is now accepting applications for the 2025 DZIF Prize for Translational Infection Research! 👉 Apply now and learn more about the award: www.dzif.de/en/apply-now...

"Among all bacterial species, S. aureus ranks second only to E. coli in the number of scientific publications." It was a pleasure to contribute to this review, with @pinholab.bsky.social and Friedrich Götz journals.asm.org/doi/10.1128/...

About the enshittification of tech (and other) industries. Paul Krugman is such a good writer. paulkrugman.substack.com/p/the-genera...

Study finds #caffeine can weaken effectiveness of certain #antibiotics Substances from natural environment can trigger bacteria's alert systems – implications for future therapeutic approaches? Read the press release here: www.cmfi.uni-tuebingen.de/en/news-even... @unituebingen.bsky.social

Metals are essential for life, but they can also be toxic. Here, @johnhelmann.bsky.social gives an excellent overview on bacterial metal physiology! @natrevmicro.nature.com #SubtiWiki www.nature.com/articles/s41...

Infection and Immunity is now welcoming nominations for highly promising scientists at the assistant professor level (or equivalent) to submit research to the next New Voices in Microbiology Collection! Please nominate by the August 18 deadline using the below link: app.asm.org/account/logi...

So intriguing and relevant for opportunistic bacterial infections - by our @cmfi.bsky.social and @dzif.bsky.social PI @lisamaierlab.bsky.social

Turning MRSA into stone: doi.org/10.1038/s415...

Nature Microbiology put together a good research briefing on this Rudner lab bacterial turgor regulation/ c-di-AMP paper. A supportive quote from my peer review comments is included. #microsky #bioimaging rdcu.be/euQln