Great Microbiology Colloquium at CMFI today! Kirsten Küsel (@kuesellab.bsky.social @microverse.bsky.social) shared insights on the groundwater microbiome, plus Kyle Mason-Jones (@unituebingen.bsky.social) on soil bacteriophages. Thanks to all for great talks and discussions!

Great colloquium today! Guest speaker @pdersch.bsky.social showed how 𝘠𝘦𝘳𝘴𝘪𝘯𝘪𝘢 reprograms neutrophils during infection, causing severe inflammation and @effiebastounis.bsky.social how 𝘓𝘪𝘴𝘵𝘦𝘳𝘪𝘢 hijacks immune cells to spread. Key findings for fighting pathogens! #Microbiology #InfectBiology #BioMech

🦠🧫 a collaboration with the Institute for Tropical Medicine in Tübingen and CERMEL in Gabon @cmfi.bsky.social

🎥 New series: Paper in a Minute! CMFI researchers explain key findings from recent publications in under 60s. Ep. 1: Ana Rita Brochado @brochadolab.bsky.social on antifolate-triggered CBASS activation in V. cholerae. Watch: youtu.be/q3EErS28oMs?... #ERC #AMR @natmicrobiol.nature.com #scicomm

🎉 Congrats to @brochadolab.bsky.social @unituebingen.bsky.social on a €2M ERC Consolidator Grant for BacImmune-Decode, advancing our understanding of bacterial immunity to fight infections + AMR!! More: www.cmfi.uni-tuebingen.de/en/news-even... @erc.europa.eu #ERC #AMR #Microbiology #ScienceNews

🌍 World Antimicrobial Awareness Week 2025 🦠 Antimicrobial resistance threatens global health. Unnecessary antibiotic use accelerates resistance and makes infections harder to treat. Use antibiotics responsibly and help raise awareness. Act now! youtu.be/_Qy3aTKiVLE #WWAW2025 #AMR #GoBlue

This was a large interdisciplinary effort together with the groups of Heike Brötz-Oesterhelt within the @cmfi.bsky.social Tübingen, and @mingxunwang.bsky.social at @ucriverside.bsky.social.

How do keratinocytes sense bacterial commensals or pathogens? @cmfi.bsky.social Here is our recent review: www.sciencedirect.com/science/arti...

#Antibiotika stören das #Mikrobiom im #Darm und ebnen so den Weg für Erkrankungen. Das gilt allerdings auch für viele Nicht-Antibiotika, zeigt eine neue Studie von @ghammeranne.bsky.social und @jdlcz.bsky.social ‪vom @lisamaierlab.bsky.social am @cmfi.bsky.social ‪der @unituebingen.bsky.social‬.

A new doctor is born 😊🥳 Welcome with me Dr. Haffner, the first PhD student of the group after wonderful years @cmfi.bsky.social Michael published 8 articles & a review with 3 as 1st author.. www.science.org/doi/10.1126/... www.pnas.org/doi/10.1073/...

New paper from the group. Together with Chambers Hughes, Giovanni Vitale and our amazing collaborators, we developed a multiplexed chemical metabolomics workflow to assign functional groups in non-targeted LC-MS/MS data: www.nature.com/articles/s41... Behind the paper story: go.nature.com/45ljV4d

How are bacterial transport machineries regulated by external cues? @brochadolab.bsky.social &co identify environmental chemicals that regulate #transporter transcription, identifying the TF Rob as a key modulator of #EffluxPump expression in #Ecoli #AMR @plosbiology.org 🧪 plos.io/46pUM9Q

Study finds #caffeine can weaken effectiveness of certain #antibiotics Substances from natural environment can trigger bacteria's alert systems – implications for future therapeutic approaches? Read the press release here: www.cmfi.uni-tuebingen.de/en/news-even... @unituebingen.bsky.social

It's finally out!🎉 We known that the #microbiome confers colonization resistance against #pathogens, we know that some meds 💊 affect gut microbes 🦠 So, do 💊 alter colonization resistance? It turns out that some do! If you wanna know more, check out our latest work www.nature.com/articles/s41...

Seeing this published is even better than eating sweets! I am so happy and proud of whole @lisamaierlab.bsky.social, especially Lisa and @jdlcz.bsky.social who walked the funny/exciting/rocky road with me until the very end. Check it out! #science #microbiome #health www.nature.com/articles/s41...

Unexpected side-effect: how common medications clear the way for pathogens CMFI's @lisamaierlab.bsky.social @unituebingen.bsky.social show in @nature.com: many non-antibiotics weaken the natural protective function of the intestine. Press release: www.cmfi.uni-tuebingen.de/en/news-even...

This is work of many years and many wonderful people! 🧑‍🔬 Led by Anne Grießhammer @ghammeranne.bsky.social and me at the Maier lab @lisamaierlab.bsky.social in Tübingen @cmfi.bsky.social. Read the TL;DR and how the project and Lisa's lab grew hand in hand here: go.nature.com/3Ix8lu3

🚨 Naming Challenge: Help redefine the #glycopeptide family! 🏆Submit your idea & win 500 € + authorship credit Let’s rethink antibiotic classification—together! 🧬 Deadline: Sept 15, 2025 👉 docs.google.com/forms/d/e/1F... @nadineziemert.bsky.social #NameChallenge #NaturalProducts #Antibiotics

𝗠𝗶𝗰𝗿𝗼𝗯𝗲𝘀: 𝗞𝗲𝘆 𝗽𝗹𝗮𝘆𝗲𝗿𝘀 𝗶𝗻 𝗵𝘂𝗺𝗮𝗻 𝗵𝗲𝗮𝗹𝘁𝗵 The human microbiome—comprising trillions of microorganisms—interacts closely with our immune, metabolic, and nervous systems. It influences directly our health. On #WorldMicrobiomeDay, we celebrate the science that shows how much Microbes Matter.

Big thanks to scientific writer Libera Lo Presti for this great little piece on our recent work exploring how proton pump inhibitors (PPIs) and pH affect human gut microbes. Check it out here: go.nature.com/4lf6jNk

Die @unituebingen feiert Erfolg im Exzellencluster-Wettbewerb 🎉Freude und Jubel bei der Pressekonferenz zur Entscheidung der DFG am 22.05.25 mit gut 200 Gästen. Weitere Infos und Fotos gibt es online 👉 uni-tuebingen.de/universitaet... @cmfi.bsky.social @ml4science.bsky.social

Die Universität Tübingen erhält sechs #Exzellenzcluster, die im Rahmen der #Exzellenzstrategie vom 01.01.2026 an sieben Jahre lang gefördert werden! Darunter drei Cluster, die bereits etabliert sind und eine erneute Förderung erhalten. uni-tuebingen.de/universitaet... #ExStra #Forschung #UniTübingen

We were gathering together this evening to hear the announcement of the new clusters of excellence by the German research foundation. So happy to hear that @cmfi.bsky.social gets another round! Love the Team! #naturalproducts #fightinfections #secmet

Yeah! 7 more years for @cmfi.bsky.social So many people to thank... We are a fantastic team!

🎉 Fantastic News 🎉 Our CMFI Cluster of Excellence @unituebingen.bsky.social receives funding extension for the next seven years. Spokesperson Andreas Peschel @andreaspeschel.bsky.social: "We can now advance our research into resistance mechanisms and new antimicrobial agents!" shorturl.at/rcK1A

After her excellent PhD defense, Maryam Mahmoudi goes on a ride with her supervisor Eric Kemen. Check out her work about temp variation in plant microbiota: doi.org/10.1093/isme... doi.org/10.1128/mbio... More to come soon! @zmbp-tuebingen.bsky.social @cmfi.bsky.social @unituebingen.bsky.social

Join us in Tubingen as a Junior Research Group Leader if you do research on #ESKAPE pathogens and infections and are interested in the highly cooperative environment of @dzif.bsky.social‬ and @cmfi.bsky.social ! Please send your application or forward to colleagues! uni-tuebingen.de/universitaet...

I am happy to share our latest preprint, spearheaded by Laura Camus. We show that tyrosin-dependent interactions can foster integration of S. aureus into the nasal microbiome. @cmfi.bsky.social @lmumuenchen.bsky.social www.biorxiv.org/content/10.1...

Here are our ideas on developing tools and technologies for anaerobic bacteria! We hope you enjoy the read as much as we enjoyed brainstorming on the topic...

#Podcast Release! 🎙️Folge 4: 𝗗𝗮𝘀 𝗠𝗮𝗹𝗶𝗴𝗻𝗼𝗺 𝘂𝗻𝗱 𝗱𝗮𝘀 𝗠𝗶𝗸𝗿𝗼𝗯𝗶𝗼𝗺 🦠Wirkt sich das Mikrobiom auf die Krebsentstehung aus? 🧪🚨Ja, sagt Christoph Stein-Thoeringer. Ziel seiner Forschung sind personalisierte Medikamente gegen Darmkrebs oder Bauchspeicheldrüsenkrebs. open.spotify.com/episode/62hK...

🔬 New pathoblocker is to stop Salmonella infections early on Possible alternative treatment method for infections with antibiotic-resistant germs. 📖 Study: tinyurl.com/2s3u4hwj #Pathoblocker #Salmonella #Pathogenicity #AMR @dzif.bsky.social @unituebingen.bsky.social @mpi-bio-fml.bsky.social

New reprint from the team: Lead by @nike-wagner.bsky.social, we used our native metabolomics setup to shed new light onto the function of the CutA protein. www.biorxiv.org/content/10.1...

Study shows that (p)ppGpp-controlled GTP homeostasis is essential for maintaining the proton motive force. This ensures #bacterial survival and #antibiotic tolerance. Study by Andrea Salzer et al. points to new approaches to fight persistent infections: shorturl.at/HtJ6N @wolzc.bsky.social

You have a strong background in molecular microbiology and look for a PhD position? Join us in #Tubingen in an international, enthusiastic team team, in an excellent research environment of the EU-funded #AUREUS program euraxess.ec.europa.eu/jobs/328844 @cmfi.bsky.social

How Staph. lugdunensis controls production of its anti-S. aureus effector lugdunin @cmfi.bsky.social @dzif.bsky.social The human microbiome-derived antimicrobial lugdunin self-regulates its biosynthesis by a feed-forward mechanism journals.asm.org/doi/10.1128/...

#Podcast Release! 🎙️Folge 3: 𝗗𝗮𝘀 𝗠𝗶𝗸𝗿𝗼𝗯𝗶𝗼𝗺 Wie wirken Medikamente und welche Rolle spielt das Mikrobiom? 🚨Kommt mit uns ins Sicherheitslabor von Lisa Maier. Sie hat die Wirkung von über 1200 Medikamenten auf unser Mikrobiom getestet. open.spotify.com/episode/7Awh... @lisamaierlab.bsky.social

🎯 It’s a match! New tool PhARIS finds right phage for S. aureus in hours! 🦠 With antibiotic resistance on a rise, #phagetherapy offers precise alternative. PhARIS streamlines #MRSA treatment. 👏 Congrats to @andreaspeschel.bsky.social @jkrusche.bsky.social & team! 🔗 More: tinyurl.com/25b8kfmh

Successful start of 𝗘𝗡𝗗𝗔𝗠𝗥 𝗗𝗼𝗰𝘁𝗼𝗿𝗮𝗹 𝗡𝗲𝘁𝘄𝗼𝗿𝗸! CMFI's @lisamaierlab.bsky.social and @brochadolab.bsky.social joined Supervisory Board kick-off meeting at @embl.org Heidelberg Strong group of excellent scientists to drive pioneering research in the fight against antimicrobial resistance! 💡🌍 #ENDAMR

CMFI is listed as host institution for FRONTIERS Science Journalism in Residency Programme! Residencies (3-5 months) for early-career #journalists to focus on in-depth #science coverage. Grant grant up to 4,000 EUR/month! 📅 Deadline: 6 May ▶️https://tinyurl.com/3nua26hp Interested? Send PM

#Podcast Release! 🎙️Folge 2: 𝗣𝗮𝗹𝗲𝗼𝗺𝘆𝗰𝗶𝗻: 𝗪𝗶𝗲𝗱𝗲𝗿𝗯𝗲𝗹𝗲𝗯𝘂𝗻𝗴 𝗲𝗶𝗻𝗲𝘀 𝗨𝗿𝗮𝗻𝘁𝗶𝗯𝗶𝗼𝘁𝗶𝗸𝘂𝗺𝘀 Kommt mit uns auf eine Schatzsuche nach einem Millionen Jahre alten #Urantibiotikum – dringend benötigt angesichts ansteigender #Antibiotikaresistenzen. tinyurl.com/yc7vv58j @nadineziemert.bsky.social & Evi Stegmann

Great honor for our @dzif.bsky.social colleague and @cmfi.bsky.social PI Peter Kremsner! 👏

New preprint from our collaboration with @aliciaperezlorente.bsky.social from Diego Romero's group, who spend some time with us at @cmfi.bsky.social. It's great to see all the puzzle pieces coming together, providing a detailed snapshot of the molecular interplay between Bacillus and and Botrytis.

Can evolution run backwards? 🎙️New @acs.org Tiny Matters podcast episode with @nadineziemert.bsky.social: Some evolutionary processes are reversible and certain traits can return to earlier states.💡 Listen to the story of Nadine's journey through time to resurrect an ancient antibiotic 👇👇👇

Für alle, die Wissenschaft mit Leidenschaft verfolgen: Unser neuer #Podcast "Inside CMFI" ist da! Welches Potenzial birgt das #Mikrobiom für neuartige therapeutische Ansätze? 🎙️Folge 1: #Antibiotikaresistenzen open.spotify.com/episode/7IkK... Zu finden auf allen gängigen Plattformen: (1/2)

Together we are stronger! "Listeria in the gut: How our body cells fight infections with good communication and teamwork" @effiebastounis.bsky.social and team show, how our body cells jointly fight epithelial cells infected with Listeria monocytogenes. www.cmfi.uni-tuebingen.de/en/news-even...

Happy to share our paper describing StretchView, an accessible cell-stretching device compatible with automated live-cell videomicroscopy: doi.org/10.1002/advs...! A great collaboration with the Constantinou lab TU Braunschweig. Thanks to DFG, Universität Tübingen, @cmfi.bsky.social for supporting!

Listen to this podcast with Hannes Link, CMFI board member and professor for bacterial metabolomics at the University of Tuebingen @unituebingen.bsky.social 👇👇👇

State and future of infectious diseases research in Germany – throwback to our fantastic symposium of CoEs @cmfi.bsky.social #resist and #microverse in Berlin youtu.be/1rPuXUBtP00?...

Der CMFI Nikolaus war an der Universität Tübingen unterwegs und hat für die Studierenden und Mitarbeitenden Schokonikoläuse auf dem gesamten Campus versteckt. Sein Versteckspiel haben wir für euch gefilmt. #Nikolaus youtu.be/YK7FWOE_w_s?...

We are happy to welcome Kai Papenfort from EXC Balance of the Microverse @universität-jena. Thank you for giving insights with the interesting talk „From strings of nucleotides to collective behavior: “Lessons from Vibrio cholerae and its phages”!