My department (Biological Sciences) at the University of Delaware is looking for a new tenure track assistant professor with a research focus on biomolecular sensing broadly. 🧪#molbiol #microsky careers.udel.edu/en-us/job/50...

I left this geranium for dead last spring in a window sill and suddenly this morning I notice one green leaf and one tiny pink flower. That’s hope y’all.

The Peters lab is looking for a new team member! The role transposons play in evolution, basic mechanisms regulating transposition, and applying transposons as tools for genome modification with a special focus on guide RNA-directed transposition. cornell.wd1.myworkdayjobs.com/CornellCaree...

I am very happy to share that I have started this week as an Assistant Professor of Microbiology at the Richard A. Gillespie College of Veterinary Medicine in Harrogate, Tennessee. It has been a beautiful journey from IAAS to Ohio State to Cornell, and now to LMU-CVM.

Apply for a #PhD with @paulhoskisson.bsky.social and me on all things #Streptomyces, #evolution, #AMR, #antibiotics, #biotech! Deadline 21st November. #MicroSky please share!

quick while the government is shut down let’s all switch to metric

Come and work with me and @ariannebabina.bsky.social on #Streptomyces evolution and antibiotic production Origins of a tangled bank: Adaptation and evolution in antibiotic-producing Streptomyces www.gla.ac.uk/postgraduate... please repost

"Cascading failure" is my new favorite term

Cold shock adaptation and ribosomal RNA modifications 🦠#rnasky www.biorxiv.org/content/10.1...

Just throwing this out there as a significant conceptual advance in the field www.biorxiv.org/content/10.1...

Our lab website is live, check it out: pokorzynski-lab.squarespace.com

I can’t explain why but the last five years are one year, and then January through August is one year, and then September through December is one year but like a different year

Check out our new paper: a review of translational coupling, the phenomenon where translation of one prokaryotic gene can promote translation of the gene downstream. We cover the history, and delve into the mechanism, which is still not fully understood. journals.asm.org/doi/10.1128/...

Attention DC area microbiologists! Save the date for CAPFA/ASM DC Branch's Fall Meeting Friday, Oct. 17th at Howard University. More info: www.washingtondcasm.org/2025-fall-me... @asmdcbranch.bsky.social

A paper cake for 👇🏾 pubmed.ncbi.nlm.nih.gov/39602291/ Thanks to my talented and thoughtful wife, this has become a lab tradition. Excellent team effort by @dipanwitab.bsky.social, Asher, @lilymcknight.bsky.social, and Pilar! Congrats! 👏🏾

Mechanism of 30S subunit recognition and modification by the conserved bacterial ribosomal RNA methyltransferase RsmI #microsky #rnasky 🦠 www.biorxiv.org/content/10.1...

Here is a link to a new pre-print that is a collaborative effort between our lab and the lab of Michelle Wang here at Cornell. We use single-molecule techniques to investigate how the combination of Rad51 and Rad54 remodels donor DNA during the homology search www.biorxiv.org/cgi/content/...

Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to @isabellalin.bsky.social who left for grad school this week and her mentor @cassidyprints.bsky.social! www.biorxiv.org/content/10.1...

De novo engineered guide RNA-directed transposition with TnpB-family proteins reveals features of naturally evolved systems www.biorxiv.org/content/10.1...

Want to know how lipidation of some nascent chains takes place by NMT2-- Check our latest work on how NAC couples Protein Synthesis with Nascent Polypeptide Myristoylation on the Ribosome out today @embojournal.org‬: www.embopress.org/doi/full/10....

Awesome work from my mentee @isabellalin.bsky.social on sporulation in non-model Bacilli!!

#MicroSky probably no less intriguing than the programmed frameshift in dnaX, which is also conserved across various phyla

We are hiring at all levels, so please help spread the word! #RNAsky #ribosomes #signaling #translation sinha.biochem.utah.edu/join

I am delighted to share that I have started my lab in the Dept. of Biochemistry @uofubiochem.bsky.social at the University of Utah @utah.edu. My laboratory will study key aspects of protein synthesis and translational control in healthy and diseased states. #RNAsky sinha.biochem.utah.edu

schaechter.asmblog.org/schaechter/2... #MicroSky

Sea star wasting disease represents a suite of stress responses. Recent work by Prentice et al (2025) identified Vibrio pectenicida FHCF-3 as causing a SSW condition in Pycnopodia helianthoides. I investigated this bacterium’s autecology. www.biorxiv.org/content/10.1...

Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: www.biorxiv.org/content/10.1...

Latest from the lab! Analysis of everyone’s favorite regulatory mechanism in bacteria — the RF2 programmed frameshift! Likely present in the ancestor of bacteria, use of this mechanism is influenced by stop codon usage! Big congrats to @cassidyprints.bsky.social journals.asm.org/doi/10.1128/...

Just published the first chapter of my thesis! 🥰 E. coli regulates the levels of a translation release factor (RF2) via a *purposeful* frameshift during translation. We found that most other bacteria do this too and it's likely an ancient mechanism! journals.asm.org/doi/10.1128/...

Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out @natsmb.nature.com🥳 rdcu.be/eBbrH A massive team effort led by @leonieanton.bsky.social Meseret Haile & Wenjing Cheng in collaboration with Jerzy Dziekan & the Alan Cowman! #TeamTomo

The original circos plot? From the 1947-1948 Carnegie Yearbook, the page prior to McClintock's Mutable Loci in Maize paper.

Congrats to former BCDB graduate student Julia Tanquary whose research on the specificity of bacterial toxin RelE for its cognate antitoxin RelB was recently published in the JBC! 1/6 www.jbc.org/article/S002...

The B. subtilis histidine-containing phosphocarrier protein (HPr) supports PTS-sugar import, interacts with GAPDH, and helps mediate carbon catabolite repression (CCR). Here, a mutant HPr protein is shown to alleviate metabolic intoxication in a cpgA mutant. journals.asm.org/doi/10.1128/...

Amazing day today in Hawaii furthering our work on Diadema scuticociliatosis. Started the day collecting a further suite of diadematid urchins for microbiome studies, followed by SEM work at UH Manoa to study ciliate morphology. Grad student @brayan-vilanova.bsky.social killing it out here!

Outstanding graduate student @kevinengland.bsky.social gives his first talk at an international meeting at #Phages 2025. He crushed it 🦠

#Phages 2025! In the midst of the current catastrophe I felt so lucky to be with my awesome lab and our amazing science community this week. Hope all our paths cross again soon!

📣 Hello Wisconsin! #phages

Is anyone going to the Molecular Genetics of Bacteria and Phages meeting next week? #Phages25?

New from our lab in @narjournal.bsky.social: We dissect the folding dynamics of a fundamental element of RNA secondary structure—a stem-loop—at single-molecule and microsecond resolution. doi.org/10.1093/nar/... 1/5

My first co–first author paper with the amazing PoPo @popomicro.bsky.social is now on bioRxiv ! 🧬 We found that Tn7-like transposons - known for finding specific insertion sites before they jump - aren’t just in bacteria. They're in archaea distributed across all major superphyla!

Tn7 family transposons that include all of the guide RNA-directed transposons (CAST) are common in bacteria. We now find diverse representatives across archaea, with many in the Asgard group. Reviving an Asgard element confirmed the exciting behaviors of the family #MicroSky #TESky

Structure of an archaeal ribosome reveals a divergent active site and hibernation factor | Nature Microbiology https://www.nature.com/articles/s41564-025-02065-w

Portulaca living it’s best 🌱

Fantastic opportunity to start your independent career at the JIC here. Great startup package. Repost = nice. Thank you!!!

New review from our lab! Compartmentalization during bacterial spore formation. Focusing on latest discoveries in Bacillus subtilis #subtiwiki www.sciencedirect.com/science/arti...

I show this video in my course every year. What a treasure we had.

Franklin W. Stahl, 95, Dies; Helped Create a ‘Beautiful’ DNA Experiment - The New York Times share.google/NgXlXURI5g2M...

Feels a little weird to announce good personal news in times like these, but I’m very excited to share that I will be starting as an assistant teaching professor in the microbiology dept at UW this fall! I’ve had such a great time as a postdoc in this department and I’m so happy I get to stay!

BREAKING: American evangelicals are considering worshiping Satan after discovering how woke Jesus Christ was.