For the last 5 years, my lab has focused on developing mutational scanning methods and learning how to answer specific questions in protein biology. @matthewkhoward.bsky.social and I wrote a review on experimental decisions and future directions for our nascent field! doi.org/10.1146/annu...

The symbiotic relationship between Ned Ruby's lab, who focus primarily on the bacteria, Vibrio fischeri and Margaret McFall-Ngai's lab, who focus primarily on the bobtail squid, has led to a deep understanding of what symbiosis really means at the molecular level youtu.be/M5rZ52wcQ08

🚨VIROMICS WORKSHOP 2026🚨 Application is now OPEN for the 8th International Viromics Workshop, Oct. 14-16, 2026, in-person at Ohio State University. Application closes Aug. 7. Apply: forms.gle/pJFLDCNEBvAe... Full details: u.osu.edu/viruslab/vir... #viromics #viruses #ecology #workshop

Folks quick to dump on the fact that latest group of amazing @hypothesisfund.bsky.social awardees are all men (n=5) are encouraged to check out the list of all recent awardees to celebrate all their achievements: www.hypothesisfund.org/portfolio

🙋🏾‍♀️I am honored to have been supported by @hypothesisfund.bsky.social and can attest that they intentionally select their awardees. There is incredible representation at the scout level as well. Have nothing but good things to say about HF leadership - there is always improvement but the bar is high!

Incredibly proud of Messi Haile @mehsehret.bsky.social, a founding member of the Ho Lab, for her beautiful work uncovering the inner workings of a central piece of the malaria parasite invasion machinery: the malarial moving junction, out today in @cellpress.bsky.social! tinyurl.com/4p3md2eb 🦠❄️🔬

🔬 Announcing our newest awardees! 🌟 These brilliant minds are pushing boundaries across microbiology, immunology, infectious disease, earth systems, and neuroscience. Celebrate with us as we highlight their projects today👇 in our 🧵: 1/ bit.ly/HFAwardees

1/ Mitochondrial Na⁺ links metabolism, Ca2+ signaling and disease. We know how it gets in, how it gets out, and proteins that use it. But: we've never actually seen Na⁺ in single mitochondria in live cells. We started with an unusual observation, went down a rabbit hole & found some cool biology .

Katalin Karikó's inspiring story captures the power of persisting against all odds -- a timely reminder for us in science. We're proud to have produced this winning episode, in partnership w/ @scifri.bsky.social. Stories like hers are at the ❤️ of why we support early-stage, unconventional science.

Great to see HF Awardee Tim Cernak chat with our friends at @scifri.bsky.social!

Always bring us joy to see our HF folks together!

Don't miss @hypothesisfund.bsky.social awardee Tim Cernak on @scifri.bsky.social! Incredible mission-driven science that we are proud to support! He is also currently hiring a postdoc: careers.umich.edu/job_detail/2... www.sciencefriday.com/segments/wil...

A novel angle on antibiotic resistance may come from understanding how bacteria protect themselves from viruses. Dr. Karasov’s bold new project explores how bacterial antiviral defense systems could reveal entirely new insights into antibiotic resistance and fundamental biology.

We are recruiting participants for endometriosis research. Our lab is studying menstrual blood to develop better diagnostic and therapeutic tools for endometriosis. If you would like to participate, please complete this survey: redcap.berkeley.edu/surveys/?s=8... #Endometriosis #WomenHealth

The @hypothesisfund.bsky.social has awarded a prestigious seed grant to @uofubiology.bsky.social professor Talia Karasov, who researches the microbial weapons bacteria inflict on each other in an evolutionary arms race that might hold the keys to addressing the threat of antibiotic resistance.

Univ. Utah biologist (the amazing Talia Karasov) wins seed grant to deepen research into tailocins, the weapons microbes use on each other. attheu.utah.edu/facultystaff... @hypothesisfund.bsky.social @utah.edu

Please check out my interview on the Out of Patients Podcast with @oliverbogler.bsky.social. We chatted about the hidden curriculum and my experience starting @ucdavis.bsky.social, feeling like a failure, and being supported by the Life Science Editors Foundation. podcasts.apple.com/us/podcast/s...

Very excited to share the most recent review from our lab, available online and soon in #BiochemSocTrans! This review covers an area of ongoing research in the lab: the role of TAM receptors in the spread of non-enveloped viruses portlandpress.com/biochemsoctr...

The Bisson Lab at IU (bissonlab.com) is hiring makers/builders/engineers across all career stages to join our team in one of the most exciting and crazy projects I've set to work on. Candidates can email us: [email protected] More info in the thread [1/3]

I’m honored to join the Scouts of the Hypothesis Fund @hypothesisfund.bsky.social and help bring beautiful, hard-to-categorize, and easy-to-underestimate biological questions to the fore. Excited for this!

Meet new #HFScout Cigall Kadoch, whose pioneering research has fundamentally changed how we understand chromatin remodeling – the regulatory machinery that controls which genes🧬 get turned on and off. 1/

Say hello to #HFScout Denise Okafor (@cdokafor.bsky.social), who combines powerful computer simulations + experimental approaches to study protein-ligand interactions–which has wide-ranging implications for metabolic diseases, reproductive conditions, & infectious diseases. 1/

Welcome #HFScout Kay Bidle, a molecular microbial oceanographer whose pioneering research on marine phytoplankton-virus interactions, ocean physics ⛈️, and ecosystem dynamics 🪼 is transforming our understanding of the Earth’s carbon cycle. 🌎 1/

👋 Meet #HFScout Orit Peleg (@oritpeleg.bsky.social), trained as a physicist + computer scientist whose research combines theory, computation, experiments, & field biology to study how groups of organisms sense, decide, & build together, e.g. the fascinating collective behavior of honeybees🐝. 1/

🤩 We’re thrilled to announce 4 new Hypothesis Fund Scouts - congratulations and welcome to Orit Peleg, Kay Bidle, Denise Okafor, and Cigall Kadoch! Follow along today to learn more about each new Scout and join us in celebrating them! 1/

New paper out today with Karinne Tennenbaum, @karlycohen.bsky.social, and Chas Bissell! We show that Cyclothone (most abundant fish in the sea) have unique teeth & they appear in the Earliest Eocene >40 million years earlier than their oldest body fossils. royalsocietypublishing.org/rspb/article...

The gentle reminder I needed to continue to show up authentically in science! Grateful and overjoyed.

I’m so honored to be included in this Hypothesis Fund cohort and grateful for this investment in our research! 🥲

📣 Bold science alert! We're thrilled to announce our latest awardees who are pushing the boundaries of research in aging, regeneration, and bacterial resilience. bit.ly/HFAwardees Hear from the #HFScouts who championed these talented scientists👇 in our 🧵: 1/

New publication out @natcomms.nature.com! We identify novel viruses that actively infect highly productive chemoautotrophs, and reveal key trophic interactions and virus-host dynamics that impact microbial carbon cycling in aphotic environments. www.nature.com/articles/s41...

I also had the great pleasure of meeting the visionary leader behind @hypothesisfund.bsky.social, who joined my research talk and had great advice afterwards on people to connect to who get excited about similar scientific questions!

How do words arise from human neurons?🧠💬 In his #NAS163 research briefing, Edward F. Chang (UCSF) will reveal how thousands of neurons encode speech at cellular resolution, linking brain activity to phonetics, word structure & language itself. Register: nasonline.swoogo.com/NAS163_resea...

Happy #InternationalWomensDay to the brilliant women in our Hypothesis Fund community who are taking the intellectual risks to pursue bold ideas, supporting one another, and transforming science together. You inspire us every day. 💫 #IWD2026

STARS in our pockets! Check out our shiniest research to date!

Evolution navigated billions of challenges to get to us to where we are today. Directed evolution compresses this to a 1D axis. Imagine if you could sample 200 dimensions at once, with data to boot 📈 First @chorylab.bsky.social PACE preprint on our new system to tackle this: bit.ly/turboprance

New paper from @adjiep.bsky.social on viral impacts in groundwater at Nature Comms. Congratulations Adjie and team! Read: www.nature.com/articles/s41... #viruses #viromics #groundwater

Big congrats to HF Awardees @stevenbanik.bsky.social and @herdelineardona.bsky.social for being awarded Sloan Research Fellowships! 🤩

Congratulations new Sloan Fellow @stevenbanik.bsky.social @stanford-chemh.bsky.social 👏

Zheng Kuang is uncovering how gut microbes may influence which gene isoforms our cells use. Supported by a new grant from @hypothesisfund.bsky.social, his work could reveal new links between diet, the microbiome and disease, opening doors to novel RNA‑based therapies. 🧪 #Biology #MolecularBiology

📣Announcing our first awardees of 2026🌠, who are setting out to uncover new knowledge about microbes in extreme environments, host-microbiome interactions, & bacterial defenses. bit.ly/HFAwardees Hear why our #HFScouts recommended these talented scientists👇 in our 🧵:

Hear about Devaki Bhaya's work on cyanobacteria in last week's @scifri.bsky.social episode! www.sciencefriday.com/segments/lig...

Our lastest publication on a new killer toxin produced by a yeast isolated from a fungus-growing ant garden! journals.asm.org/doi/10.1128/...

I'm immensely grateful for Hypothesis Fund support! For years, we've speculated about "rules" for mixotroph metabolic flexibility. This funding will allow us to integrate new mol & cell bio tools with our modeling optimization approaches. Thank you 🙏 to scout Ginger Armbrust for finding us!

This is a huge honor and we’re so excited to get started on this new direction for our group stemming from the work of William McLaughlin, a Ph.D. Candidate in our lab! Major thanks to our scout, Paul Turner and Hypothesis Fund for seeing the potential in this project! Time to get to work! 🧬🧫🧪

✨Announcing our newest awardees, who are taking scientific leaps to uncover new knowledge across microbial ecology, marine microbiology, and mammalian genetics. Learn about their projects: bit.ly/HFAwardees Meet our awardees and hear from their #HFScouts in our 🧵/1

Our next extraordinary biologist is Manu Prakash, plenary speaker at the Biologists @ 100 conference, who was recently interviewed for @jcellsci.bsky.social. #100biologists @prakashlab.bsky.social

Congratulations to the 2025 winners of the international @aaas.org Kavli Science Journalism Awards! Read the full list of this year's winners—including journalists from Australia, Canada, France, the Netherlands, Norway, and the United Kingdom: bit.ly/4oCwZtq

🎉 Big news! We've been awarded the 2025 @aaas.org Kavli Science Journalism Gold Award for The Leap, our audio documentary that features the scientists behind some of the biggest breakthroughs of our time. sjawards.aaas.org/news/2025-aa... 1/

It was lovely speaking to @harmitmalik.bsky.social for @dmmjournal.bsky.social Infectious Disease Special Issue. We chatted about his work on host-viral evolution, the importance of blue-skies research and his approach to creating a supportive lab environment journals.biologists.com/dmm/article/...

The ocean’s got rhythm — and so do its viruses. With the Bermuda Atlantic Time-Series (BATS), we dove deep — every 4 to 12 hours — to see how viral populations swing through day and night.