How do words arise from human neurons?🧠💬 In his #NAS163 research briefing, Edward F. Chang (UCSF) will reveal how thousands of neurons encode speech at cellular resolution, linking brain activity to phonetics, word structure & language itself. Register: nasonline.swoogo.com/NAS163_resea...

Happy #InternationalWomensDay to the brilliant women in our Hypothesis Fund community who are taking the intellectual risks to pursue bold ideas, supporting one another, and transforming science together. You inspire us every day. 💫 #IWD2026

STARS in our pockets! Check out our shiniest research to date!

Evolution navigated billions of challenges to get to us to where we are today. Directed evolution compresses this to a 1D axis. Imagine if you could sample 200 dimensions at once, with data to boot 📈 First @chorylab.bsky.social PACE preprint on our new system to tackle this: bit.ly/turboprance

New paper from @adjiep.bsky.social on viral impacts in groundwater at Nature Comms. Congratulations Adjie and team! Read: www.nature.com/articles/s41... #viruses #viromics #groundwater

Big congrats to HF Awardees @stevenbanik.bsky.social and @herdelineardona.bsky.social for being awarded Sloan Research Fellowships! 🤩

Congratulations new Sloan Fellow @stevenbanik.bsky.social @stanford-chemh.bsky.social 👏

Zheng Kuang is uncovering how gut microbes may influence which gene isoforms our cells use. Supported by a new grant from @hypothesisfund.bsky.social, his work could reveal new links between diet, the microbiome and disease, opening doors to novel RNA‑based therapies. 🧪 #Biology #MolecularBiology

📣Announcing our first awardees of 2026🌠, who are setting out to uncover new knowledge about microbes in extreme environments, host-microbiome interactions, & bacterial defenses. bit.ly/HFAwardees Hear why our #HFScouts recommended these talented scientists👇 in our 🧵:

Hear about Devaki Bhaya's work on cyanobacteria in last week's @scifri.bsky.social episode! www.sciencefriday.com/segments/lig...

Our lastest publication on a new killer toxin produced by a yeast isolated from a fungus-growing ant garden! journals.asm.org/doi/10.1128/...

I'm immensely grateful for Hypothesis Fund support! For years, we've speculated about "rules" for mixotroph metabolic flexibility. This funding will allow us to integrate new mol & cell bio tools with our modeling optimization approaches. Thank you 🙏 to scout Ginger Armbrust for finding us!

This is a huge honor and we’re so excited to get started on this new direction for our group stemming from the work of William McLaughlin, a Ph.D. Candidate in our lab! Major thanks to our scout, Paul Turner and Hypothesis Fund for seeing the potential in this project! Time to get to work! 🧬🧫🧪

✨Announcing our newest awardees, who are taking scientific leaps to uncover new knowledge across microbial ecology, marine microbiology, and mammalian genetics. Learn about their projects: bit.ly/HFAwardees Meet our awardees and hear from their #HFScouts in our 🧵/1

Our next extraordinary biologist is Manu Prakash, plenary speaker at the Biologists @ 100 conference, who was recently interviewed for @jcellsci.bsky.social. #100biologists @prakashlab.bsky.social

Congratulations to the 2025 winners of the international @aaas.org Kavli Science Journalism Awards! Read the full list of this year's winners—including journalists from Australia, Canada, France, the Netherlands, Norway, and the United Kingdom: bit.ly/4oCwZtq

🎉 Big news! We've been awarded the 2025 @aaas.org Kavli Science Journalism Gold Award for The Leap, our audio documentary that features the scientists behind some of the biggest breakthroughs of our time. sjawards.aaas.org/news/2025-aa... 1/

It was lovely speaking to @harmitmalik.bsky.social for @dmmjournal.bsky.social Infectious Disease Special Issue. We chatted about his work on host-viral evolution, the importance of blue-skies research and his approach to creating a supportive lab environment journals.biologists.com/dmm/article/...

The ocean’s got rhythm — and so do its viruses. With the Bermuda Atlantic Time-Series (BATS), we dove deep — every 4 to 12 hours — to see how viral populations swing through day and night.

🤩Say hi to #HFScout Dipti Nayak, whose pioneering work on methanogenic archaea (a special group of ancient microbes) is transforming how we understand early life on Earth 🌎 and informing new strategies to address climate change. 1/

👋Meet #HFScout Roseanna Zia, whose research on colloids (small particles suspended in fluid) has reshaped our understanding of complex fluids, soft matter physics, and the physics of life itself. 1/

📣Exciting day at the @HypothesisFund! We’re thrilled to recognize two new brilliant scientist Scouts: Roseanna Zia and Dipti Nayak! 1/

Congrats to @zjahed.bsky.social on receiving a seed grant from the @hypothesisfund.bsky.social to explore mechanisms of aging in cells that don't divide, like those in the brain and heart. Her work could shed new light on the progression of many age-related diseases. today.ucsd.edu/story/uc-san...

🌟New awards alert!✨ We're thrilled to announce new awards in the diverse disciplines of materials science, aging, and RNA biology. Meet these talented scientists and hear from the Scouts who recommended them below!

Learn more: bit.ly/HFAwardees 1/

Big congrats to HF Awardee @sciencekyle.bsky.social for being awarded the prestigious NIH DP2 award to continue his work on engineering immune cells to tackle cancer. So incredibly proud to have supported the early stages of this groundbreaking science -- go Kyle! 🥳 news.stanford.edu/stories/2025...

Big congrats to #HFScout @sullivan-lab.bsky.social for receiving an ASM award for his contributions to environmental research! 🎉

🚨 New tool for viral genomics! Meet CLAE: a high-fidelity Nanopore sequencing strategy that pushes accuracy to Q30, boosts throughput >800 Mb/100 pores, and recovers full-length viral genomes from complex samples 🌊🦠 👉 [https://doi.org/10.1002/advs.202505978] #viromics #nanopore #genomics

While on an expedition in the Arctic❄️, #HFScout @prakashlab.bsky.social made a fascinating discovery about ice diatoms. Check out his new manuscript! (To learn more about Manu's quest to see every organism on earth, revisit his episode of The Leap: www.sciencefriday.com/segments/man...)

We turned 3⃣ this year! Our founder & CEO David Sanford reflects on the incredible science we've enabled, and the people who made it possible. Read about our journey: www.linkedin.com/pulse/three-...

I am excited to share that I received an award from the National Science Foundation! I'm considering candidates for up to two postdoc positions - reach out by Aug 28th for full consideration. sites.google.com/uncc.edu/mic...

Congratulations to @bendeskylab.com on being awarded a @hypothesisfund.bsky.social seed grant! He’s asking why some of an animal’s genes are switched on and others off, depending on which parent the genes came from. And how evolution shapes this phenomenon, called genetic imprinting. 🧠🧬

Incredibly honored to receive support from the Hypothesis Fund!

🤩 New awards announcement! ✨ We're excited to announce our latest awardees who are tackling bold research that spans immunology, plant biology, and genetics. Learn more about these talented scientists below! Discover our full portfolio: bit.ly/HFAwardees 1/

🚨New Marlin Lab publication✨ app.jove.com/v/67112/prof... In this #JoVE, we share a method for extracting meaningful, uninstructed behavioral readouts from constrained video recording environments (🧵1/2) Led @brimcr.bsky.social & @AmirLawen, a @zuckermanbrain.bsky.social collab w/ @ItamarKahn.

Our #CryoET story on how a top antimalarial drug candidate perturbs the native malarial translation machinery is out @natsmb.nature.com🥳 rdcu.be/eBbrH A massive team effort led by @leonieanton.bsky.social Meseret Haile & Wenjing Cheng in collaboration with Jerzy Dziekan & the Alan Cowman! #TeamTomo

Big congrats to Hypothesis Fund Awardee @bjmarlin.bsky.social! We're proud early supporters of her research on transgenerational epigenetic inheritance, and can't wait to see what she'll discover next! Go Bianca! 🌟

Evolution’s eye game is wild, but mollusks take it to another level CRISPR in apple snails gives us a new model to dissect how nature rebuilds complex organs like the camera-type eyes we humans possess It turns out Evolution doesn’t just innovate, it rewinds, remixes, & regenerates rdcu.be/ezw0t

So excited to participate in this panel discussing the history and future of #PalaeoPERCS and the amazing, inclusive, and absolutely brilliant international community of early career pal(a)eo scientists! Please join us at 15:00 UTC today for this really important discussion!

📣 Bold science alert! We're thrilled to announce our newest awardees whose projects span neuroscience, bacteriology, & synthetic biology. Join us in celebrating them as we showcase their research projects below! Meet all of our awardees: bit.ly/HFAwardees. 1/

In the final episode of The Leap, Oceanographer Victoria Orphan (center) and her colleagues embark on one of the deepest science dives ever. Then, things start going awry. Explore *the entire* 10-part series now, from @hypothesisfund.bsky.social and SciFri: buff.ly/5lNhOmV

🌊New Episode 🌊 @caltech.edu oceanographer & @hypothesisfund.bsky.social scientific advisor Victoria Orphan was in the #Alvin submersible on her deepest dive yet... when the sub started misbehaving. A deep sea dive you’ll never forget on The Leap👇

@drkhaynes.bsky.social isn’t trying to fit in. Like when she was invited to a scientific conference & decided to bring a 3’x4’ stretched canvas & live-paint her poster🎨. Listen to her story on The Leap (HF + @scifri.bsky.social): www.sciencefriday.com/segments/eve... 📷: @phylogenomics.bsky.social

I am deeply honored & moved to have my story featured in The Leap from NPR Science Friday. It’s a story about being a multi-layered STEM outlier (identity & technical approach) and a testament to the power of support from #STEMdads and #STEMparents @scifri.bsky.social @hypothesisfund.bsky.social

Hypothesis Fund Scout Karmella Haynes (@drkhaynes.bsky.social) is working on the cutting edge of the cutting edge. And that’s not an easy place to be. Listen to the latest episode of The Leap!

When the world thinks your project is impossible, how do you keep going? Listen to Steve Squyres talk about his bumpy ride to Mars on The Leap (from @hypothesisfund.bsky.social , via @scifri.bsky.social ): www.sciencefriday.com/segments/mar...

🔴🚀 New episode of The Leap! 💫 Spirit and Opportunity, the first rovers to explore Mars’s surface, almost didn’t leave the launchpad. “There were so many times when I thought ‘This is it, it’s over.’” --Steve Squyres Listen below!

🍾Congrats to HF Awardee Filipa Rijo-Ferreira for being named a @hhmi.org Freeman Hrabowski Scholar! As a proud early supporter of her malaria + circadian rhythms research, we can't wait for the discoveries she makes next! We're celebrating w/ you, Filipa! 🥳 publichealth.berkeley.edu/articles/spo...

“A hypothesis requires a certain amount of madness.” 💫😵‍💫 --Piers Coleman (of Rutgers-Newark) dropping gems on this episode of The Leap, from @hypothesisfund.bsky.social & @scifri.bsky.social . 🎧 Listen here: www.sciencefriday.com/segments/you...

Grateful for the @hypothesisfund.bsky.social and excited for more cool science!

Physicist Suchitra Sebastian might have discovered a new state of matter. The hardest part may be convincing the doubters. Hear about her "impossible" finding and career in Ep. 7 of "The Leap." By @hypothesisfund.bsky.social‬ + ‪SciFri: buff.ly/kfMkYkM