Bella Lin
@isabellalin.bsky.social
📤 21
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PhD student @ Harvard Med | Cornell alum
reposted by
Bella Lin
Heather Feaga
about 1 month ago
Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to
@isabellalin.bsky.social
who left for grad school this week and her mentor
@cassidyprints.bsky.social
!
www.biorxiv.org/content/10.1...
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Conservation of sporulation genes and a transmembrane-containing Spo0B variant in Paenibacillus
Sporulation is a strategy employed by many bacteria to survive harsh environmental conditions. The genus Paenibacillus includes spore-forming species notorious for spoiling pasteurized dairy products ...
https://www.biorxiv.org/content/10.1101/2025.08.24.672004v1
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reposted by
Bella Lin
Cassidy Prince
about 1 month ago
Awesome work from my mentee
@isabellalin.bsky.social
on sporulation in non-model Bacilli!!
add a skeleton here at some point
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reposted by
Bella Lin
Cassidy Prince
about 1 month ago
Just published the first chapter of my thesis! 🥰 E. coli regulates the levels of a translation release factor (RF2) via a *purposeful* frameshift during translation. We found that most other bacteria do this too and it's likely an ancient mechanism!
journals.asm.org/doi/10.1128/...
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Conservation and evolution of the programmed ribosomal frameshift in prfB across the bacterial domain | mBio
Translation termination is catalyzed by one of two release factors in bacteria, RF1 or RF2. It has been known for decades that RF2 levels in Escherichia coli are regulated by a programmed ribosomal frameshift within the prfB gene that encodes RF2. We ...
https://journals.asm.org/doi/10.1128/mbio.01055-25
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reposted by
Bella Lin
Heather Feaga
7 months ago
Bella Lin
@isabellalin.bsky.social
will be attending Harvard BBS for her PhD!! We’re so proud of you Bella! 🍾🎉
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