Check out the final version of this work, out today! @natcomms.nature.com www.nature.com/articles/s41...

This work was also our first time doing membrane localization (way to go Cassidy)! And so proud of Bella’s gorgeous Paenibacillus tree showing the distribution of the transmembrane containing Spo0B! Also it’s the lab’s first paper without ribosomes 🫨, but don’t worry - the ribosomes made the Spo0B!

rince & JB Editor's Choice: Lin, Prince & Feaga identified sporulation genes via analyzing almost 1500 genomes. They show that that an unusual membrane-localized variant of Spo0B is found throughout Paenibacillaceae. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology

The sporulation phosphorelay protein Spo0B is membrane localized in Paenibacillus! The transmembrane domain appears to increase interaction with relay partners. Congrats to former lab undergrad @isabellalin.bsky.social and her grad mentor @cassidyprints.bsky.social journals.asm.org/doi/10.1128/...

the thing about a yarn festival is people want me soooo bad it makes them look stupid

As national medical, scientific, public health and patient organizations, we call for the resignation of HHS Secretary Robert F. Kennedy Jr. to ensure the health of the American people. Read our statement: asm.org/press-releas...

Here we show that >90% of Paenibacillus encode a unique Spo0B with a transmembrane domain! TM domain helps it interact with its phosphorelay partners. Congrats to @isabellalin.bsky.social who left for grad school this week and her mentor @cassidyprints.bsky.social! www.biorxiv.org/content/10.1...

Awesome work from my mentee @isabellalin.bsky.social on sporulation in non-model Bacilli!!

Latest from the lab! Analysis of everyone’s favorite regulatory mechanism in bacteria — the RF2 programmed frameshift! Likely present in the ancestor of bacteria, use of this mechanism is influenced by stop codon usage! Big congrats to @cassidyprints.bsky.social journals.asm.org/doi/10.1128/...

Just published the first chapter of my thesis! 🥰 E. coli regulates the levels of a translation release factor (RF2) via a *purposeful* frameshift during translation. We found that most other bacteria do this too and it's likely an ancient mechanism! journals.asm.org/doi/10.1128/...

Latest work from the lab - we identify a translation factor, YebC2, that reduces ribosome stalling in B. subtilis! Congrats to co-first authors: grad students Hye-Rim Hong & Cassidy Prince & undergrad Dennis Wu @denniswu02.bsky.social journals.plos.org/plosgenetics...