(1/2) The preprint of our perspective on genetic estimates of relatedness in animal populations is out! Big Congratulations to Annika! doi.org/10.32942/X28... A systematic review of 2,861 articles shows that, even in 2025, 75% of such studies use microsatellites. And most use only a few! #PopGen

New review! Theory & a practical guide to structural variants in popgen🧬 Many thanks to my co-authors: @rebekahoomen.bsky.social @annatigano.bsky.social @marenwellenreuther.bsky.social @janawold.bsky.social @dlfield.bsky.social @clairemerot.bsky.social onlinelibrary.wiley.com/doi/10.1111/...

My second dissertation paper is now out in @natcomms.nature.com! Here we introduce the co-expression-wide association study (COWAS) method for identifying pairs of genes or proteins whose genetically regulated co-expression is associated with complex traits. 🧵⬇️ www.nature.com/articles/s41...

The Influence of Demographic History and Genetic Architecture on Complex Traits via Runs of Homozygosity https://www.biorxiv.org/content/10.64898/2025.12.17.694908v1

Happy to share my work with my advisor Zachary Szpiech! Why are associations between ROH & complex traits inconsistent across studies? We use realistic simulations to show how demographic history and genetic architecture interact to shape the phenotypic impact of ROH. www.biorxiv.org/content/10.6...

I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵

Really excited to see this work, led by Mike Grundler, published! It's a new method for inferring the geographic locations of shared genetic ancestors. In the paper, we and use it to infer the geographic history of human genetic ancestry www.science.org/doi/10.1126/...

Thrilled to have a new paper out where we use 12+ years of monitoring data to document the impacts of inbreeding on fitness in eastern massasauga rattlesnakes! www.pnas.org/doi/10.1073/...

Excited for our publication on how the geographic scale of a sample affects the discovery of rare, deleterious variants to be out this week. With a mix of theory, simulation, and data analysis, we show when samples are narrow vs broad, the number of variants discovered and their frequencies change

I am thrilled to share this paper outlining some ideas I’ve been thinking about for a little while on a simple but powerful approach for predicting risk of inbreeding depression from long runs of homozygosity and non-ROH heterozygosity. 1/n @klohmueller.bsky.social doi.org/10.1016/j.tr...