Nicole Kleman
@nicole-kleman.bsky.social
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PhD student in the Zaidi Lab @ University of Minnesota studying statistical and population genetics
reposted by
Nicole Kleman
Sol Taylor-Brill
3 months ago
Excited to present my poster, “Tissue-Related Heterogeneity in Genetic Architecture of mtDNA Copy Number” (Board 5081), on Wednesday at
#ASHG2025
!
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Excited to be presenting my poster “Residual Stratification and Increased Genetic Diversity in Multi-ancestry GWAS”, Board 1062T on Thursday, October 16 from 2:30pm-4:30pm at
#ASHG2025
!
3 months ago
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reposted by
Nicole Kleman
Genetics Society of America
6 months ago
New in
#GENETICS
: Huang et al. describe biases in SNP & local ancestry heritability as functions of admixture history and the genetic architecture of the trait, clarifying their interpretation and implication for
#GWAS
& polygenic prediction in population admixture. Read more:
buff.ly/1xB3Mpu
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reposted by
Nicole Kleman
Esha Bandyopadhyay, Ph.D.
6 months ago
Please register if you haven't already done so. MidWest PopGen is happening in August at the University of Minnesota (Twin Cities)—abstract deadline for talk: July 11th, and poster: August 1st.
sites.google.com/umn.edu/mwpg...
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MWPG2025
Join us for the 10th Midwest Population Genetics conference, held at the University of Minnesota Twin Cities from August 21 - August 22, 2025.
https://sites.google.com/umn.edu/mwpg2025/home
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reposted by
Nicole Kleman
Arslan Zaidi
8 months ago
Our paper on the theoretical properties of SNP heritability in admixed populations is out in Genetics:
academic.oup.com/genetics/adv...
with
@jinguohuang.bsky.social
,
@nicole-kleman.bsky.social
, Saonli Basu, and Mark Shriver
add a skeleton here at some point
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reposted by
Nicole Kleman
Arslan Zaidi
9 months ago
An update to our preprint led by
@jinguohuang.bsky.social
and
@nicole-kleman.bsky.social
on interpreting SNP heritability in admixed populations, now with HE regression and LD Score regression in addition to GREML.
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Interpreting SNP heritability in admixed populations
SNP heritability (h2snp) is defined as the proportion of phenotypic variance explained by genotyped SNPs and is believed to be a lower bound of heritability (h2), being equal to it if all causal varia...
https://www.biorxiv.org/content/10.1101/2023.08.04.551959v4
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