Jinguo Huang
@jinguohuang.bsky.social
๐ค 35
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Computational biologist | Popgen/statgen, human complex traits
reposted by
Jinguo Huang
Aaron Quinlan (he/him)
6 days ago
We are thrilled to announce the first official release (v0.1.8) of
#๐ฏ๐ฒ๐ฑ๐ฑ๐ฒ๐ฟ
, the successor to one of our flagship tool,
#๐ฏ๐ฒ๐ฑ๐๐ผ๐ผ๐น๐
! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n
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Intro to Bedder โ The Quinlan Lab
http://quinlanlab.org/blogposts/bedder_intro.html
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reposted by
Jinguo Huang
Roshni Patel
6 days ago
As promised, a longer thread on what I consider to be some of the most interesting and important contributions of this paper (1/10)
add a skeleton here at some point
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reposted by
Jinguo Huang
Roshni Patel
6 days ago
Excited to share work from my postdoc with
@docedge.bsky.social
and collaborators Matt Pennell and
@jgschraiber.bsky.social
, newly out over the weekend:
www.biorxiv.org/content/10.1...
(1/6)
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Observational epidemiological studies can mitigate genetic confounding with the genetic relatedness matrix
Observational studies are commonly used in psychology and epidemiology to identify risk factors correlated with health outcomes. However, these studies are vulnerable to confounding when shared geneti...
https://www.biorxiv.org/content/10.1101/2025.11.24.690292v1
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reposted by
Jinguo Huang
Sol Taylor-Brill
about 2 months ago
Excited to present my poster, โTissue-Related Heterogeneity in Genetic Architecture of mtDNA Copy Numberโ (Board 5081), on Wednesday at
#ASHG2025
!
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reposted by
Jinguo Huang
Nicole Kleman
about 2 months ago
Excited to be presenting my poster โResidual Stratification and Increased Genetic Diversity in Multi-ancestry GWASโ, Board 1062T on Thursday, October 16 from 2:30pm-4:30pm at
#ASHG2025
!
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reposted by
Jinguo Huang
Arslan Zaidi
7 months ago
Our paper on the theoretical properties of SNP heritability in admixed populations is out in Genetics:
academic.oup.com/genetics/adv...
with
@jinguohuang.bsky.social
,
@nicole-kleman.bsky.social
, Saonli Basu, and Mark Shriver
add a skeleton here at some point
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reposted by
Jinguo Huang
Arslan Zaidi
8 months ago
An update to our preprint led by
@jinguohuang.bsky.social
and
@nicole-kleman.bsky.social
on interpreting SNP heritability in admixed populations, now with HE regression and LD Score regression in addition to GREML.
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Interpreting SNP heritability in admixed populations
SNP heritability (h2snp) is defined as the proportion of phenotypic variance explained by genotyped SNPs and is believed to be a lower bound of heritability (h2), being equal to it if all causal varia...
https://www.biorxiv.org/content/10.1101/2023.08.04.551959v4
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