the market has come around to rationally expecting the market to stay irrational when it comes to elon musk stocks

I remember being fascinated at the time to learn some of the same things that make fruit flies so annoying make them great for research. You can make a shit ton of fruit flies very easily

The DOGE screwworm story is a perfect time to reminisce about Sarah Palin speaking to a conference on autism and blasting the govt for not helping them and instead wasting money on “fruit fly research in Paris” when fruit flies are foundational to genetic research and had applications to autism

Now published: journals.plos.org/plosbiology/...

I don't think he was a terrible candidate, I probably would have voted for him over Becerra. But between Steyer / Schulz / Bloomberg flops for president and now this, billionaires should accept Trump was able to do it b/c he was a household name celebrity TV star, not because he was a billionaire.

Women's wages have grown *faster* than the cost of childcare (which is mostly "the wages of *other* women who are not augmenting their productivity with technology").

what this means is they are going to fully obliterate black representation in the state

AOC in a short interview explains how she appreciates Hunter Biden’s advocacy for his battle against illegal substances, pointing out his active role in helping those who are in that situation.

Nope. This is an extremely well studied phenomena - here's an article I wrote a few years ago about it: www.city-journal.org/article/the-...

This is going to end with a D trifecta raising the cap via reconciliation.

On the contrary, I think the idea that there is some golden past that we should return to is precisely what fascists exploit to seize power. The world is complicated, there are problems, but America of 2024 was the best of all Americas to live in, for most groups of people.

Three weeks left to apply to our postdoc position on alpine plant resilience! Us: Three years of funding, an awesome collaborative team, a gorgeous study system, blueberry pie, unionized postdocs. You: A PhD and experience in ancient DNA, paleoecology, and/or plant genetics and genomics.

it’s true that california should invest in faster vote counting because it is ridiculous that it takes this long but that has nothing to do with the conspiracy theories, republicans create conspiracy theories about every single election they lose no matter how it’s counted

They are destroying science because they think that publicly funded science is bad, and that it's especially bad when it benefits anyone that isn't a white man.

I really hate how the dumbest people alive have polarized me into becoming a Chesterton's fence guy

Exciting new work from the lab led by @lagiven.bsky.social & co-advised by @tododge.bsky.social mapping pigmentation variation in the swordtail X. nezahualcoyotl! Spotting variation is linked to xmrk but embedded in complex genomic regions that Tris & Lyle tackled with UL nanopore: shorturl.at/Ljw1z

I have discovered that most angry reactionary voters aren’t even voting for any particular political reason, they’re just laundering their frustration with life through a voting booth. That’s all it is

I have often said that we put our prisons in white rural areas as a white rural jobs program. And at least in the Midwest and Northeast, it is true that prisons are in very white places. But at first blush no more white than we'd see by chance. This really undermines a narrative I have shared.

Yes - there's actually some good research on this directly (you can see food prices fluctuate with SNAP cycles)

It failed in totally predictable ways - exactly the ways Remain warned it would. A catastrophic failure of the information environment that UK voters were so badly misled about the consequences of the Brexit vote

NSF seems to have stopped making new awards last week. There have been no new awards from any directorate since Weds, June 3. Even with the slow pace of new awards this year, there's been a consistent trickle. Something stopped the flow. grant-witness.us/funding_curv... #NSF 🧪

That’s not to say everything is perfect, but if you could press a button and be transported to a job from the 1970s at your approximate economic strata, most people would be smart to refrain from pressing.

Here’s a SERIOUS question. What if our property tax system was actually fair, and was based on public costs actually incurred to support housing? What if low density housing had to pay its way, rather than being subsidized by responsible infill housing? What if we stopped incentivizing sprawl?

Other large counties in California also live stream their ballot operations. If systematic election fraud exists in California, it's in the smaller Republican counties that hide their operations.

You’re not allowed to be racist anymore because that’s racist. bsky.app/profile/atru...

Talk of limiting grants, by number or by dollars, should be informed by data. It’s been a long time since we got NIH information on grants per PI. drugmonkey.scientopia.org/2013/01/30/p...

This is deep, conspiracy level bullshit, very easily refuted with easily available empirical data. California is full of faux progressives like this. I really hope the younger generation can organize to overcome them.

NEW from me: an explanation of Friday's court decision that restarts immigration processing for hundreds of thousands of people currently inside the United States. www.americanimmigrationcouncil.org/blog/court-b...

Some things I like about America: Miles Davis Abstract Expressionism Christian McCaffrey scoring a Touchdown Metro Center The Smithsonian Manhattan Queens Lincoln Park, Chicago Chicago Alden Ralph Lauren Moby Dick 30th St Station

reminder that the last time trump was at madison square garden was for a literal nazi rally

These onerous taxes on new housing need to go. If cities and the state do not exempt new housing, the Jarvis initiative may do it for them, and go beyond just exempting new housing. missionlocal.org/2026/06/sf-m...

Being trans legitimately is the best thing that ever happened to me. Despite everything - the dysphoria, the conversion therapy, being disowned by my parents and family, the discrimination, having to sue the state just to be allowed to practice law without submitting to genital inspections -

The number of Black NIH-funded Fellows has plummeted by a staggering 40% from 2024 to 2025; for Hispanic trainees the number has fallen by 33%. These figures are nothing short of horrifying. The Trump administration is stealing the future of science.

Almost like the media likes Trump and wants him to rule over us!

Once again observing that no one ever ran "President Biden's approval ratings have tumbled. But here in West Baltimore, these black lesbians say he delivered on key promises.

Again the response to every coastal city elitist talking about how you'll never be a Real part of Muh Culture is to post this image of what their seething hatred of new apartment buildings has gotten them:

Honest to goodness, there was a time not so long ago when this would have been a massive scandal.

American fascists are fucking up everything.

Yeah the idea that people who aren't born in New York City but choose to live there aren't "real" New Yorkers but the people who inhabit the bloodsucking white-flight suburbs that oppress the city are...woof. bsky.app/profile/made...

OH MY GOD I GET TO TALK ABOUT MY THESIS I specifically studied the instance of election fraud within a 1/2 point margin of victory. I'm calling them whisker thin elections. Fraudulent elections are proportionately less likely to be whisker-thin than other close margins of victory. 1/

When Johnson uses terms like “diabolical” and “impossible to prove,” he’s encouraging extrajudicial solutions to his asserted problems.

a 2 point lead before whatever oppo dumps we've got coming isn't super reassuring.

Once again, the nonexistence of mass voter fraud is a scientifically proven fact, backed by mountains of decades of data, akin to the knowledge that the sun rises in the East & water has both adhesive & cohesive properties. There should be consequences in public life for constantly lying otherwise.

Seeing videos where people are snarky about saying "Oh you idiot, don't you know food surpluses lead to inequality?" without bothering to think for a moment about the trade-offs is gonna turn me insane

Overall, models learn some type of generalized survival landscape (which mutations kill the protein, which do not), but they can't do much beyond this. Large-scale benchmarks obscure the fact that model predictions are often poor for specific tasks, such as picking beneficial mutations. 5/5

The fundamental problem is that zero-shot predictions know nothing about the phenotype of interest, and different phenotypes don't have to correlate. Therefore, zero-shot prediction has a fundamental problem that no model improvements can overcome. 2/

New paper about zero-shot predictions of mutational effects. There's a lot of misunderstanding about what such predictions can and cannot do. In brief, they're good at identifying deleterious mutations but bad at predicting fitness improvements. 1/ www.biorxiv.org/content/10.6...

POLITICO: “.. A federal judge has ruled Trump's $100,000 H-1B visa fee is an unauthorized tax on businesses and must be vacated.” @kyledcheney.bsky.social storage.courtlistener.com/recap/gov.us...