Our preprint list highlighting new tools and techniques in imaging is now up on FocalPlane. Check it out, and let us know if we are missing any research that we should add to the list. focalplane.biologists.com/2026/04/03/m...

A non-invasive approach for understanding localized force generation in 3D tissues https://www.biorxiv.org/content/10.64898/2026.04.01.715811v1

prochain webinaire #MAIIA : vendredi prochain 3 avril à 12h. Nous aurons le plaisir d’accueillir Clément Benedetti qui nous présentera Open-source image analysis on massive 3D images using meshes and Blender Zoom 👇: u-paris.zoom.us/j/8574788077... ID : 857 4788 0773 Pass : 471884 webinaire en Fr

Mood : youtu.be/G9JGBXhk_lY?...

Latest #CDlab paper on BioRxiv: www.biorxiv.org/content/10.6... PhD student Bert van Herck developed a route towards efficiently delivering lipids and proteins to synthetic cells through DNA-driven fusion of SUVs to GUVs. Great collaboration with labs of Gijsje Koendrink & Stefan Vogel.

What tool would you use to characterize the 3D shape of nuclei, particularly invagination or blebs?

How to make your own robot! A review of people making awesome lab robots out of commercial 3D printers. Thank you @vsaggiomo.bsky.social and Sander for inviting me to help write this paper in @digital-discovery.rsc.org. Beep boop! 🤖 #chemsky doi.org/10.1039/D5DD...

🤖AI tools for peer-review? I want to share my experience using q.e.d. science (www.qedscience.com), a reviewing tool with high-profile endorsements. I will report results and my impressions from the use /1

The next the Ethel Browne Harvey Postdoc Seminar will be held Friday, April 10 at 3 pm Eastern Time with Joaquín Navajas Acedo @mads100tist.bsky.social @biozentrum.unibas.ch and Yiqun Wang @ucsandiego.bsky.social. Register today and join us. bit.ly/42xUhYh #SDBPostdocSeminar

📣 Submission deadline extended for special issue "Taking the Stage: The Future of Microscopy"! The Journal of Microscopy has launched an open call for papers for an exciting new special issue which will feature submissions by Early Career Researchers. Deadline extended: 30 April 2026

Used the combo Cellpose-Sam, Trackmate, Celltrackscollab... Super fast from I2K

1/ 🚀 Excited to release: napari-mcp - agentic control of napari from any MCP-capable AI assistant! Use it for interactive image processing, analysis, and visualisation! Really cool project from @ilan-theodoro.bsky.social from my team! #napari #bioimageanalysis #MCP @biohub

I put together a visual LLM Architecture Gallery that collects (~50) recent open-weight model designs in one place. Architecture diagrams, config links, tech reports, explainers... you name it! Hopefully useful as a reference & learning resource: sebastianraschka.com/llm-architec...

I'm happy to present our new tool, EpiCure, a napari plugin to ease correction of segmentation and tracking of epithelia movies, developed in @devstempasteur.bsky.social

Enlighting

mechano-adaptation, kind of

🐍 Learn Python for Image Analysis — for free! UK life scientists: join EuroBioImaging's hands-on beginner course at The Crick in London (23–25 June), running simultaneously with sites in CZ, PT and SWE! ⏰ Register by 15 April — places are limited! ✈️ Travel funding may be available shorturl.at/v3Vsk

If anyone wants to follow along, here is the repo for my vibecoded in-terminal plasmid editor with GenBank import. Loooots of features to add and bugs to sort, but feel free to play around! Check back often as this will be a continually improved app. github.com/Binomica-Lab...

I am very excited to share this preprint which has been my main postdoc project! We identified leupaxin as a negative regulator of durotaxis via paxillin-FAK inhibition in MDA-MB-231 brain and bone tropic metastatic variants. www.biorxiv.org/content/10.6...

I am happy to share that our paper is now available online at Advanced Science @wiley.com advanced.onlinelibrary.wiley.com/doi/epdf/10....

Faure, L. M., Gómez‐González, M., Baguer, O., Comelles, J., ... & Roca‐Cusachs, P. (2024). 3D Micropatterned Traction Force Microscopy: A Technique to Control 3D Cell Shape While Measuring Cell‐Substrate Force Transmission. Advanced Science, 11(46), 2406932. #EpithelialMechanics buff.ly/Mpt1o3g

One concept. One minute. Better #microscopy. MDIBL Light Microscopy Facility just launched Light Microscopy Fundamentals—a new YouTube series breaking down the basics of light microscopy in quick, bite-sized videos. #microscopymonday #fluorescentproteins #lightsheet #SciEd #AcademicSky 🧪 🍎

A new webinar series is born - ''MechanoBioTalks - Mechanics, Materials and Living Matter", to bring together and inspire researchers interested in biomechanics, biophysics and biology across different kingdoms of life. Join us! For info and registration visit green-te.nl/activities/

Last week I shared results showing large variability between Imaris/Arivis/Aivia vs Python/ImageJ/CellProfiler. Much was due to small code issues (x/y swaps, microns vs pixels). After fixing, results are much closer—no big log-scale gaps. Some variability remains, but large errors weren’t real.

An amazing example of actin imaging with our expansion microscopy probe for actin HAK-actin™. These are U-ExM expanded platelets stained with HAK-Actin (magenta bottom), (anti-integrin αIIb magenta top), and fibrin (fibrinogen-A488, green). Movie from preprint www.biorxiv.org/content/10.6... 🧪

We want to organize a learnathon to teach plugin development within #FIJI #scijava #imglib2 #BigDataViewer and other Big* parts of the Java ecosystem. Please spread the word, and if you know someone who can be interested, forward them the link below forum.image.sc/t/learnathon...

loaded with lots of exciting stuff

Not just soft

Two papers on important roles of the Arp2/3 complex in microglia in the CNS microenvironment by the labs of Jeremy Rotty and Tim Lämmermann @laemmermann-lab.bsky.social @mpi-ie.bsky.social and ZMBE @uni-muenster.de. Read more: link.springer.com/article/10.1... link.springer.com/article/10.1...

Converted my old elastix + transformix Java wrapper to use the appose.org approach with Opus. Total cost? $12. Worth it.

1/3 🇫🇷 We are excited to join the 2nd FBI Mechanobiology Meeting 2026 in Paris! Anja will present the “Latest Applications in Fast & Precise Photomanipulation” 🗓️ Thu 26/03 🕒 11:45–12:05 📍Come meet us & discuss your mechanobiological workflow. #Mechanobiology #Microscopy #Bioimaging #Photomanipulation

Deb Roy, Inoue et al. @jhu.edu introduce an #optogenetics tool to rapidly induce #microtubule acetylation in living cells and show that this triggers release of the RhoGEF GEF-H1 from #microtubules, thereby driving persistent directional cell migration. rupress.org/jcb/article/... #Cytoskeleton

On the front cover of issue 6 of Lab on a Chip and from our reviews issue: On-chip characterization of cell mechanics assisted by external physical fields and artificial intelligence. Xiaoming Liu, Zhuo Chen et al. pubs.rsc.org/en/content/a...

Despite it being chaotic, active nematic turbulence can give rise to arrested labyrinthine patterns! Check out our new paper @physrevresearch.bsky.social! Work led by Ido Lavi, with Jean-François Joanny and Jaume Casademunt. journals.aps.org/prresearch/a...

First paper as first & corresponding author, out in PLOS Computational Biology! 🎉 napariTFM brings traction force & monolayer stress microscopy into napari, accessible via GUI; open-source, validated and no coding required. 😉 Check it out 👇

It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪

Got a notebook you’d like to turn into a desktop app? Explore the LabConstrictor GitHub repository 🔗 github.com/CellMigratio... And check out this demo repository built with LabConstrictor to see a simple example of the result 🔗 github.com/CellMigratio...

Would I use this for a complex piece of software that I had to maintain for years and release to the public? Probably not. But the question "I need software to do this, should I look if someone has built it or should I just make it myself" no longer has a simple answer.

#Cosyne2026 check out poster 3-104 by @atika-syeda.bsky.social to learn about the impact of behaviors on visual cortical activity 🧠 🐭

Very happy to announce a short article on Fishfeats, with @gaellel.bsky.social ‬and @zenlabpasteur.bsky.social, now accepted in Bioinformatics doi.org/10.1093/bioi...

This👇💙

A small polymerase ribozyme that can synthesize itself and its complementary strand | Science www.science.org/doi/10.1126/...

🚀 Great to see @eurobioimaging.bsky.social highlight the innovative #EnderScope, a low-cost, open-source microscopy system expanding access to imaging! 🔬👏 Kudos to Jérôme Mutterer (IBMP microscopy platform). ▶️ www.eurobioimaging.eu/news/innovat...

Friday, 13:15 (Poster 2-048) at @cosynemeeting.bsky.social #cosyne2026: @allierced.bsky.social and @lappalainenjk.bsky.social present how they made GNNs learn interpretable circuit models from neural activity. Code: saalfeldlab.github.io/flyvis-gnn/

On the inside front cover of Lab on a Chip's reviews issue 2026: Light driven polymer thin films as flying robotic chips in the sky. #OpenAccess from Jianfeng Yang & Hao Zeng Read now: pubs.rsc.org/en/content/a...

We have developed a new AI-based assay to rapidly identify new molecular targets to inhibit cancer cell migration and metastasis. See more details here: www.science.org/doi/10.1126/...

Let's get ready for a full month of training in image analysis in @pasteur.fr , this summer! Are you interested in learning how to do bioimage analysis? For light microscopy? for cryo-EM? And for cellular cryo-EM? Stay tuned, Pasteur offers access to THREE courses, this June. 👇🎓

Do you know those annoying layer lines you get with FDM 3D printers? Those layers you try to avoid or hide?  What if I tell you we can use them to make 15-micrometer-tall microfluidic channels? chemrxiv.org/doi/full/10.... 1/5 #chemsky the