Fabrice Senger
@senger.bsky.social
📤 767
📥 414
📝 628
Mechanobiology / Multi-cellular assemblies
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Fabrice Senger
Club Exo Endo
about 7 hours ago
📢 Registration for the 28th Annual Meeting of the Club Exocytose-Endocytose is open until April 15 ! 👉 Register here:
exoendo.org/en/evenement...
Please share widely!
@gdrimabio.bsky.social
@biologists.bsky.social
@sbcf.bsky.social
@embo.org
@febsletters.bsky.social
@sneuroendo.bsky.social
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Fabrice Senger
Club Exo Endo
about 21 hours ago
exoendo.org/offre-demplo...
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Horizon Europe - MSCA- Post-doc
Institut des Neurosciences Cellulaires et Intégrative, Strasbourg -
https://exoendo.org/offre-demploi/horizon-europe-msca-post-doc
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Exciting Instruments
about 8 hours ago
🚀 Big news from
@timcraggs.bsky.social
x
#BPS2026
: meet the new EI-FLEX Pro! Automated alignment + focus, real-time analysis with publication-ready plots, modular upgrade to 96/384 wells, no darkroom or optical table, compact benchtop. Meet us at booth 401 or get in touch for a demo!
#singlemolecule
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Dave Barry
4 days ago
Do you do image analysis? Want to make it more robust and reproducible? Have you heard of containers, but don't know why they’re useful, and how to use them?
@martinjones.bsky.social
will explain all:
crick.zoom.us/webinar/regi...
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Welcome! You are invited to join a webinar: CCP-volumeEM Show and Tell - February 2026. After registering, you will receive a confirmation email about joining the webinar.
'A brief introduction to the use of containers for reproducible image analysis' with Dr Martin Jones Abstract: Reproducibility of scientific data analysis is critical, but can be particularly challe...
https://crick.zoom.us/webinar/register/WN_L4k3th99TQiLTW-Z5EQ7cw#/registration
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Jorge Barrasa Fano
about 8 hours ago
📰 Check out our new paper published in Nature Protocols
@natureportfolio.nature.com
!! Great work by Apeksha Shapeti and Janne de Jong, in which they explain everything you need to know to perform 3D traction force microscopy on multicellular systems!!
www.nature.com/articles/s41...
(1/3)
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Investigation of mechanical forces during multicellular early angiogenic sprouting by three-dimensional traction force microscopy in hydrogel matrices - Nature Protocols
Investigating mechanical forces during angiogenic sprouting by three-dimensional traction force microscopy (TFM) in hydrogel matrices, including steps to analyze and interpret cell–extracellular matri...
https://www.nature.com/articles/s41596-025-01275-0
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Michael Way
1 day ago
Closing date is 19th Feb so why not go for it to enjoy the rain in London!
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Stephen Royle
1 day ago
New paper from Honnor et al. (with a small contribution from me) "A geometrically informed permutation test for dependency in spatiotemporal patterns of protein species in microscopic images" New statistical approach to studying colocalisation in microscopy. 🧪
doi.org/10.1016/j.jt...
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Redirecting
https://doi.org/10.1016/j.jtbi.2026.112409
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Jeremy Baskin
3 days ago
And save >80% on the cost by pooling 6 or more plasmids into a single sample using our free SAVEMONEY algorithm!
elifesciences.org/articles/88794
colab.research.google.com/github/Masaa...
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Ryota IINO 飯野亮太
3 days ago
Takanori’s new preprint is out! We revealed mechanism of particle size-dependent and -independent performance metrics! Artificial DNA-nano/microparticle motors: Factors governing speed, run-length, and unidirectionality revealed by geometry-based kinetic simulations
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.02.11.705463v1
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Carmelo Ferrai
3 days ago
Tread -1- EpiSci - I am very proud to share with you our new study that you can access on
@biorxivpreprint.bsky.social
(see link below) "The Interaction with Nanotopographical Environment regulates nuclear mechanoresponse in mESCs via Histone Demethylase KDM3A.
www.biorxiv.org/content/10.6...
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Henry De Belly
4 days ago
My lab
@cri-utsw.bsky.social
is looking for a highly motivated postdoct interested in mechanobiology! We are building a highly collaborative and interdisciplinary team working on how mechanical forces shape immune and cancer cell behavior. Come do cool science with me!
lnkd.in/gKEXWUGy
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LinkedIn
This link will take you to a page that’s not on LinkedIn
https://lnkd.in/gKEXWUGy
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Jon Humphries
4 days ago
Actn4 Links Inactive Integrin α5 With Actin in Zebrafish Somites
www.sciencedirect.com/science/arti...
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Actn4 Links Inactive Integrin α5 With Actin in Zebrafish Somites
Integrins are key plasma membrane proteins that mediate cell-ECM adhesion and communication, and they rely on a conformational change for their activa…
https://www.sciencedirect.com/science/article/pii/S1535947625001860?via%3Dihub
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Jon Humphries
5 days ago
FCHo2, not talin, enables inside-out activation of integrin ɑvβ5 in curved adhesions
www.nature.com/articles/s41...
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FCHo2, not talin, enables inside-out activation of integrin ɑvβ5 in curved adhesions - Nature Communications
Talin has been believed to be indispensable for integrin activation. Here, the authors show that the curvature-sensing protein FCHo2, not talin, enables inside-out activation of integrin ɑvβ5 in curve...
https://www.nature.com/articles/s41467-026-68942-y
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Fabrice Senger
Jorge Díaz
5 days ago
Honored to see our work featured in a JCB Spotlight by Pacheco and
@drericabiophd.bsky.social
(@UCSF). The piece discusses our study revealing distinct force-generating mechanisms in epithelial and mesenchymal collective migration 🔬🐸 Thank you for your careful review of our work!
hubs.la/Q042GFYY0
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Jörg Enderlein
5 days ago
Check out this quick petition to defend Europe's environmental laws against pressure from polluters. 1 minute to sign. Would really help if you shared it too!
#HandsOffNature
www.wwf.eu/campaigns/ha...
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#HandsOffNature
#HandsOffNature
https://www.wwf.eu/campaigns/handsoffnature/?utm_source=newsletter&utm_medium=email&utm_campaign=nl11feb&utm=.share.bluesky
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Denis Wirtz
9 days ago
I will be giving talks at UC San Diego (Dept Bioengineering) and Sanford Burnham Prebys Institute this coming Friday and the following Tuesday in La Jolla. I will talk about 3D mapping of solid tumors and new CAR T therapies to resolve them. Hope to see you there.
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Guillaume Jacquemet
6 days ago
Delighted to share our latest preprint "Filopodia-mediated trans-endocytosis"
www.biorxiv.org/content/10.6...
Work driven by many people including Hanna, Marcela, Sujan, Marie-Catherine, Anna and Monika. Fantastic collaboration with Johanna Englund, Emilia Peuhu, and Eija Jokitalo
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Juan Nunez-Iglesias
6 days ago
smart microscopy postdoc position in Montpellier, France. Could definitely do worse. With
@glyg
https://forum.image.sc/t/up-to-4-year-postdoc-position-in-montpellier-smart-microscopy/119201
#foss
#microscopy
#getfedihired
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Fabrice Senger
Atika Syeda
12 days ago
Excited to share “Orofacial behaviors, not eye movements, govern neural activity in mouse visual cortex”
www.biorxiv.org/content/10.6...
Summary below...
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Carsen Stringer
8 days ago
🚨 new work from the lab on how eye movements 👀 versus orofacial movements influence 🐭 visual cortex activity 🧠
#neuroscience
#behavior
#neuroAI
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What's up? Sunday evening...
youtu.be/hRzlbh4or3c?...
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King Krule - Easy Easy (Official Video)
YouTube video by King Krule
https://youtu.be/hRzlbh4or3c?si=NY512xaQXy-wDnXo
9 days ago
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I have no clue about that subject, but, I'm ready to go
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10 days ago
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Fabrice Senger
Denis Wirtz
10 days ago
In spatial omic, using standard 2D sections undersamples 3D tumors and tissues, always. We asked how many slides or cores of a TMA are needed to capture the variations in tissue composition in a single 3D tumor? A lot! Download here:
www.sciencedirect.com/science/arti...
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Three-dimensional assessments are necessary to determine the true, spatially resolved composition of tissues
Methods for spatially resolved cellular profiling of tissue sections enable in-depth study of inter- and intra-sample heterogeneity but often profile …
https://www.sciencedirect.com/science/article/pii/S2667237525001110
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Fabrice Senger
Lucien Hinderling
10 days ago
forum.image.sc/t/announcing...
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Announcing two new Python tools for OME-Zarr (and TIFF)
I'm happy to announce a couple tools that we've been building in the OME-Zarr/OME-TIFF ecosystem 1. ome-writers A unified, common interface for writing directly to OME-Zarr or OME-TIFF as it is acqui...
https://forum.image.sc/t/announcing-two-new-python-tools-for-ome-zarr-and-tiff/119093
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Fabrice Senger
Rémi Flamary
11 days ago
We are recruiting four positions connected to Machine Learning, Statistical Learning, and AI for Science in the Applied Mathematics department at École polytechnique. Join our vibrant community at IP Paris and Hi! Paris IA center. List below🧵
tinyurl.com/3jpw9t26
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Calliopé
https://tinyurl.com/3jpw9t26
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Fabrice Senger
The Ramsey Lab
12 days ago
Final reminder 📢 We are looking for a
#philbio
or
#philphysics
postdoc for an interdisciplinary project exploring the boundary between living and nonliving systems through the lens of self-organization & active matter 👇
www.kuleuven.be/personeel/jo...
#philjobs
#philsky
#HPS
#devbio
Please share!
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FocalPlane
11 days ago
Our
#preprint
list is up on FocalPlane. This list focusses on the latest tools in bioimage analysis. Let us know if you have any recommendations to add to our list.
focalplane.biologists.com/2026/02/06/m...
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Microscopy preprints: bioimage analysis - FocalPlane
Microscopy preprints: bioimage analysis - News
https://focalplane.biologists.com/2026/02/06/microscopy-preprints-bioimage-analysis-17/
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Fabrice Senger
Michael Way
11 days ago
Postdoc job alert in the Crick Institute in London. Are you interested in the actin cytoskeleton? I am looking for a postdoc to examine the cellular, developmental or physiological role of Arp2/3 iso-complex driven actin polymerisation. Multiple aspects available.
crick.ac.uk/WayPostdoc2026
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Postdoctoral Fellow - Cellular signalling and cytoskeletal function lab
http://crick.ac.uk/WayPostdoc2026
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Fabrice Senger
12 days ago
Electrifying story from
@ritamateus.bsky.social
lab.
@mpi-cbg.de
@poldresden.bsky.social
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Fabrice Senger
Lab on a Chip
12 days ago
On the inside front cover of issue 3 of Lab on a Chip: Three-dimensional intestinal tube with a crypt-like uneven inner wall fabricated using electrolysis-generated microbubbles. Hiroaki Onoe et al.
pubs.rsc.org/en/content/a...
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Fabrice Senger
13 days ago
Hi all, Hope you're fine and safe An important
#announcement
about
#tyssue
, a Python
#epithelium
modeling library :
github.com/DamCB/tyssue...
Please 🔁 this message to reach the few and far apart people that might be impacted
#openScience
#scipy
#biologicalphysics
#modelling
🧪
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https://github.com/DamCB/tyssue/blob/main/README.md
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has someone allready used this :
github.com/sommerc/trac...
, it takes trackmate xml files and allows for MSD calculation, in python
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GitHub - sommerc/trackpal
Contribute to sommerc/trackpal development by creating an account on GitHub.
https://github.com/sommerc/trackpal
13 days ago
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Fabrice Senger
bioRxiv Cell Biology
14 days ago
Adapting the OpenFlexure Microscope for Affordable Live-Cell Imaging
https://www.biorxiv.org/content/10.64898/2026.02.02.703252v1
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Fabrice Senger
BioVoxxel (Jan Brocher)
15 days ago
Image analysis is often treated as an individual skill—leading to irreproducible pipelines and bias. Sustainable
#BioImageAnalysis
must be an institutional responsibility: training, automation, standards, and GSP-aligned guidance. Read the full article on LinkedIn:
www.linkedin.com/feed/update/...
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Fabrice Senger
Mark Peifer (He, him)
15 days ago
This is very cool. Overexpressing a stabilized Cyclin G, a transcriptional cyclin that regulates growth and the cell cycle, induces induces extreme wing size and shape variation. They perform a genome-wide screen for deficiencies that enhance or reduce this! 1/n 🧪
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Fabrice Senger
@MorieLAB
16 days ago
Please REPOST (“likes” don’t help in diffusion!) and consider applying: we work in such a fantastic context, we ask so interesting questions, and we have such a collegial and best-willing atmosphere… CRBM = Happy & Good Science
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Thiago Carvalho
16 days ago
'Cisco's security team put it plainly: "From a capability perspective, OpenClaw is groundbreaking. This is everything personal AI assistant developers have always wanted to achieve. From a security perspective, it's an absolute nightmare."'
www.forbes.com/sites/amirhu...
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An Agent Revolt: Moltbook Is Not A Good Idea
OpenClaw is a breakthrough AI assistant. Moltbook, its new social network for agents, is a security catastrophe waiting to happen.
https://www.forbes.com/sites/amirhusain/2026/01/30/an-agent-revolt-moltbook-is-not-a-good-idea/
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Marianne Bauer
18 days ago
In a really fun collaboration with Max Wilson’s lab at UCSB, we’ve developed a simple model that can capture the non-monotonic expression of Wnt target genes with respect to frequency in periodic (optogenetic) Wnt pulses:
elifesciences.org/articles/107...
. Great work Sam, Olivier, Naomi and Ryan :)
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Anti-resonance in developmental signaling regulates cell fate decisions
Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is capable of redirecting developmental fate outcomes, including germ-layer spec...
https://elifesciences.org/articles/107794
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Fabrice Senger
Nature Methods
18 days ago
HumanBase: an interactive AI platform for human biology
www.nature.com/articles/s41...
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HumanBase: an interactive AI platform for human biology - Nature Methods
Nature Methods - HumanBase: an interactive AI platform for human biology
https://www.nature.com/articles/s41592-025-02994-8
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discover f-strings today ... progress
18 days ago
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Fabrice Senger
epithelial mechanics fan club
18 days ago
Skamrahl, M., Pang, H., Ferle, M., Gottwald, J., ..., Oswald, T. A., & Janshoff, A. (2021). Tight Junction ZO Proteins Maintain Tissue Fluidity, Ensuring Efficient Collective Cell Migration. Advanced science, 8(19), e2100478.
#EpithelialMechanics
buff.ly/CB2FSa7
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has someone any hint towards a segmentation strategy combining segmentation results, as for example given by cellpose, and active contour refinement ?
19 days ago
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Fabrice Senger
Teng-Leong Chew
20 days ago
🧪 We are excited to share this novel open access paper on Phasor Mixing Coefficient to analyze colocalization, developed by folks
@i2janelia.bsky.social
and
@aicjanelia.bsky.social
. This is also the first technical paper jointly published with our sister imaging center
@malacridalab.bsky.social
!
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it was very interesting, particularly with respect to 3D photomanipulation
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19 days ago
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Alfredo Sciortino
21 days ago
This weekend we projected cells and filaments on the roof of the
@museeorsay.bsky.social
in Paris, then we contracted it with a pinch of myosin. And it was fabulous! Grateful to have been part of this art/science project & thx to
@manuelthery.bsky.social
@lblanchoin.bsky.social
& the CytoMorphoLab
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Nature Methods
22 days ago
A Comment discusses how commands, data, and metadata currently discarded by scientific instruments could be used to train AI systems to learn to conduct experiments.
@henrypinkard.bsky.social
@nilsnorlin.bsky.social
www.nature.com/articles/s41...
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The missing data for intelligent scientific instruments - Nature Methods
Most scientific instruments currently discard rich streams of commands, data and metadata from which AI systems could learn to conduct experiments with expert-level decision-making and troubleshooting...
https://www.nature.com/articles/s41592-025-02995-7
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Fabrice Senger
Benoit Ladoux
22 days ago
Happy to highlight our collaborative work from our
@ijmonod.bsky.social
team with
@destriano.bsky.social
, B. Goyeau and M. Chabanon. Cytoplasmic crowding acts as a porous medium that hinders macromolecular diffusivity. Plus: a clever way to measure cell volume.
www.pnas.org/doi/10.1073/...
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Cytoplasmic crowding acts as a porous medium reducing macromolecule diffusion | PNAS
Intracellular transport of macromolecules is crucial for the proper functioning of most cellular processes. Although intracellular crowding is know...
https://www.pnas.org/doi/10.1073/pnas.2519599123
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Manuel Thery
23 days ago
and certainly in you Buzz!
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Christophe 🔬 L
23 days ago
Huge congrats to
@manuelthery.bsky.social
and all the Cytomorpho lab. The "Living Architectures" performance at
@museeorsay.bsky.social
was breathtakingly beautiful
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bioRxiv Biophysics
24 days ago
Analyzing single-molecule dynamics with both complex types of motion and complex transition kinetics: Benchmarking of ExaTrack
https://www.biorxiv.org/content/10.64898/2026.01.22.700663v1
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