It's out! Happy to present ITEC, a semi supervised algorithm with an extremely low error rate that can track cells in files of any size (think Terabytes!). We used it in many organisms, including zebrafish, to study how organs form and linked it to gene expression www.biorxiv.org/content/10.6... +🧪

We‘re looking for a motivated Master student to join our team! Do you want to optogenetically control metabolic activity to see how metabolism affects patterning and morphogenesis? 💡🧫🧬🔬 Then please apply! #optogenetics #metabolism #devbio #hESCs Please RT. Thank you!🙏

I am thrilled to share our paper introducing RBPscan, a novel approach to profile RNA–protein interactions in living cells. Free access link at the end ⬇️ 🧵 1/ www.cell.com/molecular-ce...

#Canada 🍁 has opened prestigious CIRTA fellowship for internationally based candidates in Ph.D. and postdoctoral levels. We (Physical biology of developing systems lab at McMaster University) are interested in recruiting through that stream. Please apply / spread the word for those interested:

Oh my god, @biologyopen.bsky.social put this newbie next to John Gurdon in their @biologists.bsky.social 100-year anniversary cover dedicated to reviewers! What a lovely gift and coincidence for closing the year... 🤩

Lovely little pre-Christmas present to see this out @natcellbio.nature.com! Some 🔥 new results in here since the biorvix incl (1) a new RARE-GFP reporter ✳️🙌, (2) additional NMP quantification 🔢, (3) no neural tube patterning on RA inhibition 🙅 etc. Enjoy! 😍 www.nature.com/articles/s41...

#FluorescenceFriday bleed-through from yesterday #zebrafish 🐟🔬:

We are hiring an Imaging Scientis. Apply here: go.mbl.edu/AS1887

A picture snapped with phone camera today: a rare 'supernumerary' #rainbow over Hamilton with repeating colour sequence due to very small droplet sizes giving rise to interference patterns of #light by its #wave nature. 🧪

Fascinating timelapses of #somite clock with cadherins from Kageyama Lab @dev-journal.bsky.social : journals.biologists.com/dev/article/...! A new player in clock and #fgf gradient cross-talk besides previously discovered Dusps linking both transcriptional and post-translationally. 🧪🔬 #devbio

New BBSRC funded PhD opportunity in my group with Inspiralis Ltd and @conradn.bsky.social. If you are interested in RNA - protein interactions and RNA modifications check the details below for how to apply. @nrpdtp.bsky.social @biouea.bsky.social @earlhaminst.bsky.social tinyurl.com/bdzvn4dr

It was one-of-a-kind moment to meet Sir John Gurdon at @socdevbio.bsky.social meeting in 2019. Such a humble, down-to-earth personality who was deeply content with life! An exemplary scientist that one could find at the benchside playground regardless of age or career stage! May he rest in peace...

1/5 Lab's first manuscript 🎉 is out @biorxivpreprint.bsky.social today! Beautifully, it is performed by a senior undergraduate thesis student, Mohammed! We developed a 3-D printed #zebrafish embryo imaging chamber 🔬and connected it to syringe pumps to be able to perfuse drugs in a timely fashion. 🧪

🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/

I am excited to announce that I will be moving to IMB Mainz next year! The Winter call for the IPP PhD program is now open; if you are interested in maternal #mRNA regulation and #translation in early vertebrate development, please apply! Deadline: 16 October. More info: www.imb.de/students-pos...

🚨 The International Developmental Mechanics Zoom Seminar Series is back on Sept 25! 🎤 We have an exciting line-up of speakers this fall. See the image below for details 🌐 Website: sites.google.com/view/devmech... 📝 Interested in presenting? Sign up here: tinyurl.com/2munv5bv

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. www.nature.com/naturecareer... Please repost!

Mathematical modelling of the first fate decision This Research Highlight showcases the work from Maria Avdeeva, Madeleine Chalifoux, Bradley Joyce, Stanislav Y. Shvartsman, Eszter Posfai @eposfai.bsky.social : journals.biologists.com/dev/article/...

Preprint - Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo. www.biorxiv.org/content/10.1...

Are different cell types like oil and water? Over a century ago, researchers found that dissociated sponges and embryonic tissues can self-assemble into functional structures. Join me, @benswedlund.bsky.social to explore the differential adhesion hypothesis & its applications in tissue engineering!

CIHR rant here: our panel funded 6 (!!) out of 42 applications. That is only 14% success rate. That is as bad as the worst of times. So much good science left unfunded, labs closing, skilled workers let go. Without a $$ infusion, the Canadian research ecosystem is never going to survive and thrive.

I was interviewed recently by @stemcellpodcast.com I witter on about morphogens, notochord, @dev-journal.bsky.social & how biology is becoming a data science Thanks @stemcellpodcast.com for talking to me stemcellpodcast.com/ep-299-spina...

📣 We're on the lookout for a creative postdoc with strong computational skills! Be the go-to person in the lab for building simple but powerful simulations that test wild ideas on biological rythems: from daily cycles of mussel groups at deep sea, to firefly flash synchronization! More info below👇

Have you ever thought about inflating tissues? Or maybe quickly deflating those inflated tissues? New #EpithelialMechanics pre-print: doi.org/10.1101/2025... 🧵 with pressure control, multiscale buckling, controlled wrinkling

Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

🥰 Self-supervised, label-free 3D cell imaging is here Congrats to Cyril on this very cool first, first author publication 🏆! This started when he was a bachelor's student (and he's now completing his masters!). And many thanks to my other awesome co-authors🙏 elifesciences.org/articles/99848

Excited to share our latest work led by my PhD student Linjun Xie on sclerotome development: Dynamic BMP signaling regulates sclerotome induction and lineage diversification in zebrafish, now published on @dev-journal.bsky.social! #zebrafish #devbio 1/8 doi.org/10.1242/dev....

It’s out! 🥳 www.science.org/doi/10.1126/...

🔔 Proud to share the preprint of my PhD work in the Petridou group @nicolettapetridou.bsky.social @embl.org ✨ “A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics” 🐟 🔁 📶 🔗 www.biorxiv.org/content/10.1... #devbio #biophysics 🧵⤵️

Link to the research: www.cell.com/developmenta... @cp-devcell.bsky.social

#Science #Biologie "Information Processing in Biological Systems" 🖥️ Les vidéos colloque organisé par le Pr @thomaslecuit.bsky.social, titulaire de chaire Dynamiques du vivant, sont disponibles. 👉 www.college-de-france.fr/fr/agenda/co...

Great work by @nicoleedwds.bsky.social and colleagues!

Developmental system drift in dorsoventral patterning is linked to transitions to autonomous development in Annelida https://www.biorxiv.org/content/10.1101/2025.05.29.656861v1

Thanks for the invitation, fantastic conference out together by the organizing committee!

Canadian Developmental Biology Conference Day 3 continues - Min Zhu Postdoctoral Fellow, Hospital for Sick Children, “Tissue stiffness mapping by light sheet elastography" #CDBC2025 @socdevbio.bsky.social

Very very happy to participate in the 10th Biophysical Society of Canada annual meeting ! Opening words by Cecile Fradin/ Très heureux de participer au 10e congrès de la BSC avec le Discours Introductif de Cecile Fradin. #BSC2025

Great #zebrafish talk on tissue biomechanics going on at the @biophyscanada.bsky.social meeting @mcmasteruniversity.bsky.social given by @manningresearch.bsky.social #bsc2025

Lovely microscopy with too many -but never enough- somites in them! 🤩

Looking for MSc and PhD students to join my lab and work on vascular development in zebrafish and mouse. Feel free to share or reach out if you have questions! jobrxiv.org/job/universi...

I'm excited to join @pritiagarwal.bsky.social and @tarafinegan.bsky.social as a co-organizer for the International Developmental Mechanics Seminar Series. The series will resume in September 2025, and call for speakers is now open! More info is on our new website: sites.google.com/view/devmech...

Fluorescence lab is upon us. Time to get to know (and love) beads. #AQLM2025

Happy to share a new preprint from my lab! We characterize the on/off kinetics, light dosage-dependence, and more for a suite of optogenetic signaling activators in zebrafish embryos 💡 www.biorxiv.org/content/10.1...

Lastly : if Canada wants to be serious about this, they should massively increase tri council grants for everyone, to create those self reinforcing effects. Everything is explained in the Bouchard report ised-isde.canada.ca/site/panel-f...

It has been a while since I advertised some of the tools we have released to help researchers analyze the zebrafish genome. So a brief Bluetorial on our zebrafish genomics UCSC public data hub and the bigger effort led by @ferencmueller.bsky.social to create a zebrafish ENCODE project (Danio-CODE):

Tenure-track Faculty position just opened up in my department! If you want to be part of a dynamic group who is excited about science, apply. For more details, visit www.usherbrooke.ca/emplois/offr... Please share in your networks! #microsky

Beautiful #microscopy and science! Quite interesting that Wnt signal's role appears flipped in between cnidaria and bilateria... 🧪

1/2 We are hosting the Biophysical Society of #Canada annual meeting @mcmasteruniversity.bsky.social in May 20-23rd. This is a single stream event with sessions on #computational &theoretical #biophysics, new tools for biophysics, #development, mechanics of cells &tissues, #AI in biophysics,...🧪+

The language used by lecturer here is worrisome as well. A mistake in import documents is not stg. to be dumped on the postdocs. Rather, the lab should pay some effort to reach out to the officials to undertake the responsibility. Esp. when hired a researcher politically targeted in their country.

We are hiring! A postdoc position is available in the lab studying gene expression dynamics in Drosophila embryos, as part of a larger research effort in collaboration with @mrattray.bsky.social 🧬🔬🪰 Full details are in the ad: www.jobs.manchester.ac.uk/Job/JobDetai...