Mélanie Laurin (@melanielaurin.bsky.social)

Excited to share that our new open access review is out today: “Rho GTPases in cancer resistance: mechanisms, vulnerabilities, and therapeutic opportunities.” This work was led by Amy Beaudin, a PhD student in the lab, who did an excellent job synthesizing a rapidly evolving field.

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Rho GTPases in cancer resistance: mechanisms, vulnerabilities, and therapeutic opportunities Abstract. Intrinsic and adaptive resistance to therapy remain major barriers to effective cancer treatment. Diverse resistance mechanisms, including epithelial-mesenchymal transition, enhanced toleran... https://portlandpress.com/biochemsoctrans/article/54/5/461/237519/Rho-GTPases-in-cancer-resistance-mechanisms