New pre-print *finally* out! We've developed ToF-SIMS for in-situ glycosaminoglycan (GAG) analysis. Here's why that matters 👇📄 (1/9) www.biorxiv.org/content/10.6...

Some useful public speaking tips from Freud here.

delighted to share our new pre-print developing label-free glycosaminoglycan analysis of diverse complex biological samples, led by @h-davies-s.bsky.social working closely with David Knight and Rebecca Miller alongisde our recent recruit Samie Dalgarno www.biorxiv.org/content/10.6...

Long-lived CD163+ and Tim4+ gut macrophages in the lamina propria are spatially restricted by TGF-β rupress.org/jem/article/... @jem.org @tovah-shaw-lab.bsky.social @edinburghuni.bsky.social @manchesterup.bsky.social

We are proud to announce the discovery of Glyco-Carbohydrates, a paradigm shift in glycobiology! Traditional glycoconjugates (proteins, lipids & RNA) max out at 50% carbohydrate. Ours are 100% carbohydrate AND glycans, unlocking truly homogenous properties. TBA April 1st, 2027! 🍬 #glycotime

Defective HLA-G1 glycosylation disrupts Siglec-7–mediated NK cell tolerance at the maternal–fetal interface in recurrent pregnancy loss link.springer.com/article/10.1...

@hepworth-lab.bsky.social new paper alert. Matt and I wrote a research highlight about recent papers that describe mechanisms of ILC2-neuron crosstalk. If you're interested in reading it, check it out! onlinelibrary.wiley.com/doi/10.1111/...

Our #JuniorPI feature for #ASMB2025 spotlights @tranejoan.bsky.social from @officialuom.bsky.social, whose work explores collagen homeostasis in fibrosis and repair🔬 She is also co‑chair of ASMB Outreach, strengthening community engagement.🎥-https://youtu.be/abjDOI39WJY @themeshwork.bsky.social

Organized immunity in the CNS: What stroke reveals about neuroinflammation and lymphoid niches: doi.org/10.1172/JCI2... Catalina Lee-Chang comments on Yang et al.: doi.org/10.1172/JCI1...

Interested in how age related immune dysfunction might impact stroke risk and outcomes? Check out our systematic review led by Vanda Wen Teng Ho at the National University of Singapore www.frontiersin.org/journals/agi...

Long-lived resident tissue macrophages govern intraocular pressure homeostasis by regulating extracellular matrix turnover, contributing to resistance-generating tissues that are dysfunctional in glaucoma @cp-immunity.bsky.social www.cell.com/immunity/ful... @dukeeyecenter.bsky.social

Pleased to share our native glycomics workflow preserving O-acetylation, detecting this labile modification in rat (53%) and mouse (9%) serum N-glycans. Integrally, O-acetyls are invisible under standard reductive conditions. Now published at Molecular Omics. Link: academic.oup.com/molecular-om...

1/ We are excited to report in @sciimmunology.bsky.social that human complete and selective LFA-1 deficiency causes isolated Epidermodysplasia Verruciformis (EV). This surprising phenotype revealed a surprising mechanism 🙂 www.science.org/doi/10.1126/...

Review @annualreviews.bsky.social @gabyrabi.bsky.social Glycan-Binding Proteins in Immunity www.annualreviews.org/content/jour...

Registration for #MBE2026 is now open! Join us in Oulu 🇫🇮 for the flagship European meeting dedicated to fundamental #ECM research. ECRs and trainees, this is a unique chance to connect with leaders in the field, present your work, gain visibility, and build your network! More at www.mbe2026.org

You still have 3 days to apply to the postdoc positions available in my lab 😀 🔬Come and work with us 🔬

📣 2026 PhD studentship 📣 Via @manchester.ac.uk 's President's Doctoral Scholar Awards, we are encouraging applications for a PhD on the effect of pollutant exposure on microbe-immune cross talk. This project will incorporate microbiology, immunology, & bioinformatics. Deadline: 16 March 2026!

One week left to submit your abstract for this fantastic meeting 👇 It’s gonna be a great year for matrix meetings! 😎 Fancy a full week of matrix biology? Catch a direct flight from Manchester to Frankfurt after #BSMB and join us in Heidelberg for #DGMB2026 😉

Reposting as one week left for early bird registration and to get your abstract in!!

Vaccine-induced immune thrombocytopenia and thrombosis occurs in persons with Ig light-chain allele IGLV3-21*02 or *03 that recognizes a specific epitope on the adenoviral core protein pVII, resulting in misdirection of antibody targeting PF4 @nejm.org www.nejm.org/doi/full/10....

Prof Sheena Cruickshank @sheencr.bsky.social offers insight in The Guardian @theguardian.com on the science behind sneezing and what it reveals about our health #ImmunoSky www.theguardian.com/society/2026...

You still have time to apply if you are interested in joining my lab!!

Been on multiple search committees For me (personally so YMMV)…I basically dismiss everything that’s labeled *submitted* unless there’s a preprint I can read

Very excited to announce that registration is open for the BSMB Spring 2026 meeting in Manchester, April 13-14th. Already an amazing lineup and lots of opportunities to speak! Register, bsmb.ac.uk/meetings/ecm... @mcrcellmatrix.bsky.social

Introducing the amazing Dr Lily Koumbas Foley 🥰📚👩‍🎓 @crgglasgow.bsky.social @uofgsii.bsky.social

Dr Alexander Clarke @ajclarke.bsky.social joins us from @ox.ac.uk tomorrow to give a talk entitled: “Powering the germinal centre reaction" 📆 Thursday 5th Feb 🕛 12:00 PM 📍 Michael Smith Lecture Theatre @britsocimm.bsky.social MIG Seminar #ImmunoSky

Join us in Sheffield! We are keen to support early career researchers in applying for independent research fellowships to join our friendly & collaborative environment, in areas related to gene expression, mechanistic cell biology & cancer biology. For more info 👇 sheffield.ac.uk/biosciences/...

Science update from my postdoc Peiyuan Chai - his work “glycoRNA complexed with heparan sulfate regulates VEGF-A signaling” is now published @nature.com uncovering a new layer or glycoRNA-regulation of growth factor mediated control physiological processes rdcu.be/e1bBX

Fibroblastic reticular cells direct the initiation of T cell responses via CD44 @nature.com @the-de-lab.bsky.social www.nature.com/articles/s41...

🚨 We are hiring TWO postdocs to join the Cell Migration Lab (cellmig.org) 🇫🇮 as part of the new Centre of Excellence in Immune–Endothelial Interfaces (IMMENs). Join us to decode immune regulation & develop next-gen imaging tools! 🧪🔬 Details in thread 🧵👇 #ScienceSky #Postdoc #AcademicJobs Please RT🫶

Out now in @natchembio.nature.com: Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells 🎉 www.nature.com/articles/s41... check out the press release below! #glycotime

Have you ever wondered how many N-Glycans or #glycoproteins there are on cells? The numbers are massive: calculations suggest about 20 to 200 million N-glycans per human cell! Read the full blog post: research.bidmc.org/ncfg/blog/24... #glycobiology #glycotime #cells #biology

#Glycans probably have more "copies/cell" than #proteins and changes in #glycosylation could potentially be remarkable biomarkers for diseases as well as targets for therapeutics. This post explores the abundance of glycans on the cell surface and it is worth a read to recognize these #biomolecules.

Really looking forward to speaking (for the 3rd year!) at the British Society for Immunology (@britsocimm.bsky.social) Foundations of Immunology course on 18 March 🧬 A brilliant one-day online course covering core immunology for all backgrounds 🧪 Register 👉 www.immunology.org/training/Fou...

🚨 Job Alert! 🚨 We have an opening at our Microscopy Core Facility in Turku 🇫🇮. If you love imaging 🔬 and helping scientists succeed, we want you! 👇 abo.rekrytointi.com/paikat/index... #Microscopy #ScienceJobs #CoreFacility #Imaging @turkubioscience.bsky.social

🥳 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐥𝐚𝐭𝐞𝐬𝐭 𝐰𝐨𝐫𝐤 𝐬𝐡𝐨𝐰𝐢𝐧𝐠 𝐡𝐨𝐰 𝐩𝐨𝐥𝐲𝐬𝐢𝐚𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐚 𝐫𝐚𝐫𝐞 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐦𝐨𝐝𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧, 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐞𝐬 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐦𝐨𝐧𝐨𝐜𝐲𝐭𝐞 𝐦𝐨𝐛𝐢𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐛𝐨𝐧𝐞 𝐦𝐚𝐫𝐫𝐨𝐰. ✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social 📖 shorturl.at/IDwza 👇 A short thread...

Our lab is hiring a PhD student to investigate how glycans affect antitumor immune responses in metastases and how this can be modulated to improve immunotherapy! More info here 👇 #glycotime werkenbij.amsterdamumc.org/en/vacatures...

Delighted to share the latest paper from the lab "Fast label-free live imaging with FlowVision reveals key principles of cancer cell arrest on endothelial monolayers" Amazing work driven by @follainga.bsky.social with contributions from many. link.springer.com/article/10.1...

Don't miss out on your chance to attend "Fuelling the immune response IV: #UKimmunometabolismMeeting2026" Those that have joined before will know these are fantastic meetings providing an open & productive forum to discuss really cool science 📆16-17th April www.immunology.org/events/fuell...

Major update for unilectin.unige.ch with now more than 2800 3D-structures with annotation, literature and details of interaction!! HumanLectome also up to date. Thanks to Boris Schnider at @sib.swiss and @glycoexpasy.bsky.social for super work. More exciting news soon with LectomeXplore upgrade

Out now: We present antibody-lectin chimeras (AbLecs) as a molecular platform to target sugars, or glycans, for cancer immunotherapy. www.nature.com/articles/s41... www.nature.com/articles/s41... @mitkochinstitute.bsky.social @mitdeptofbe.bsky.social @mitcheme.bsky.social @stanford-chemh.bsky.social

🏆 Huge congratulations to our Director Professor Tracy Hussell @tracyh9494.bsky.social who has been awarded the Nature 2025 Lifetime Achievement Award for Mentoring in Science for her exceptional support of emerging scientists. #ImmunoSky @nature.com sites.manchester.ac.uk/lydia-becker...

Beautiful talk by Matt Hepworth, so many exciting things happening at barrier surfaces. @hepworth-lab.bsky.social #BSI2025 @britsocimm.bsky.social @lydiabeckeriii.bsky.social

Really looking forward to speaking about my PhD work at this webinar with @merrylabnotts.bsky.social @themeshwork.bsky.social ! 🦠🎄

Thanks for sharing @mucosalimmunol.bsky.social. This work was led by @lizihegarty.bsky.social during her PhD @edinuni-irr.bsky.social funded by @wellcometrust.bsky.social. Now being continued after our relocation to @uofgsii.bsky.social. Might be of interest to @emds2025.bsky.social attendees!

🧬 A new study by Dr Alex Eckersley and @tracyh9494.bsky.social uncovers why severe viral infections can cause long-term breathlessness & fatigue. Damage to the lung’s basement membrane may persist long after recovery - offering new targets for future therapies. #ImmunoSky tinyurl.com/2zddsj63

🔬 New research led by @douglaspdyer.bsky.social shows that CCR2-mediated monocyte recruitment is essential for limiting radiotherapy-induced intestinal toxicity - pointing to new strategies for reducing off-target tissue damage. @cruk-mi.bsky.social #ImmunoSky #Cancer #RadNet tinyurl.com/34uu4nr9