Check our new venture into drug discovery #glycotime!

Check out our new preprint "Convergent Lead Discovery Strategies Yield Covalent and Non-covalent Inhibitors of Human UDP-Galactose-4-Epimerase" on Chemrxiv led by Will Browne in close collab with GSK @jtbush.bsky.social chemrxiv.org/engage/chemr...

Here's a job at my institute that just opened up: Max Planck Director in Biological AI. This is an amazing opportunity - www.mpi-cbg.de/news-outreac...

Check out our first PhD advert, primarily for enthusiastic students with a chemical/chemoenzymatic synthesis background: www.verw.tu-dresden.de/StellAus/stelle.asp?id=12186&lang=en&style=cms2

🥳 Thrilled to share that I am starting a new position as W3 Full Professor of Biochemistry at @tudresden.bsky.social. From Aug 2025, the Chemical Glycobiology Lab will continue our mission to generate Chemical Precision Tools for #glycotime in one the most beautiful places in Germany 😊

🔥 Job alert! We are looking for an enthusiastic PhD candidate in the new Chemical Glycobiology Lab at @tudresden.bsky.social! Master in Chem or similar, experience in organic chem including chemoenzymatic, and most importantly: enthusiasm! Deadline 8th July: www.verw.tu-dresden.de/StellAus/ste...

Thank you to our organizers for putting together this program: @stephanhacker2.bsky.social Marina Rubini @borisvauzeilles.bsky.social @michellefrei17.bsky.social Hana Macíčková Cahová @drglycoben.bsky.social @mlakemeyer.bsky.social Shixian Lin @rubenragg.bsky.social Meghan Lucas (4/4)

Great to see the new concept of protein PTMs functionalization published in @chemicalscience.rsc.org! The GlyTACs enable selective degradation of glycoproteins in living cells. Congratulation to Haoyu and Liu. Have a look on the full story here: pubs.rsc.org/en/Content/A... #chembio

#chembio, #glycotime and #bioorganic crowd, join us tomorrow online ✨for free✨!!

Great news for @tudresden.bsky.social! 🎉 In addition to Physics of Life, 4 additional Excellence Clusters were funded at the TUD by the DFG @dfg.de. Congratulations to all our friends and colleagues, and especially to the Speakers of the Clusters and the TUD rector! Read more: tud.link/cfwd9z

🔥 Exciting online, free #chembio event on 28th May!! Please join us online for the hybrid ESBOC Satellite meeting! Setup as a teaser to allow for accessibility and see some of the speakers that will attend ESBOC in Gregynog/Wales. To attend, please register by sending an email: lnkd.in/e-U7C6Jb

It doesn't happen very often that you receive an award on the same day as your mentor. Congratulations to Peter Seeberger on winning the @rsc.org Khorana Award #glycotime! And I am very thankful to the amazing lab members, colleagues and mentors that led to winning the Norman Heatley Award!

We had a blast at yesterday's @rsc.org Chemical Biology Symposium. Congratulations to Teresa and Freya who were awarded a prestigious poster prize!

Nice one - congrats @nmriley.bsky.social! Well deserved for #glycotime!

We are happy to announce the new team that will organize the Virtual ChemBioTalks from this edition onwards Marina Rubini @mlakemeyer.bsky.social @michellefrei17.bsky.social Hana Macíčková Cahová @drglycoben.bsky.social @borisvauzeilles.bsky.social @stephanhacker2.bsky.social (1/4) #ChemBio #ChemSky

Join us for the #GBMLunch Lunch on April 9 (12.30 PM) Speaker: Ben Schumann @drglycoben.bsky.social from @crick.ac.uk Title: Chemical Precision Tools to Dissect Protein Glycosylation Chair: Oliver Thorn-Seshold @oliverthornseshold.bsky.social (Technische Universität Dresden)

Super proud of the lab representation at the Glycobiology GRS. Check out the work by @sandhyasridhar.bsky.social, @hc3009.bsky.social and @sophiedschmidt.bsky.social at the GRC! #glycotime

ESBOC will be epic, just saying: www.esboc.org.uk #chembio

✨​ Final Call for Oral Communication at ESBOC! ✨​ Europe pioneering conference in #BioorganicChemistry & #ChemBio, since 1967! 🎉​ Stunning Gregynog, 🏰​ Check out our brilliant lineup of speakers! 🤩🤩 🔗​ Register: esboc.org.uk/?p=1208 We can't wait to see you there🤩

Super cool, like the use of diazirines to fix the lipids in place! Also some #glycotime inside the #lipidtime!

Woop woop #proudPI

Such an amazing symposium! Here with @davidsharp.bsky.social who presented his work on a modular approach to photoswitchable sugars - stay tuned on this! #glycotime

I am so excited about having been admitted as a Fellow of the Royal Society of Chemistry @rsc.org 🥳 this is only possible through the help of an amazing team, supportive mentors and the #glycotime field being just absolutely fantastic!

Amazing speaker lineup (Imperiali, Seeberger, Aye, Gonzalez Bello, Walport, Walport, Vendrell, Kele, Zeymer, Green, Thorn-Seshold, Biber) and beautiful venue - join us at #ESBOC58 in Gregynog/Wales on 28th-30th May for amazing #chembio and #bioorganic. Speaker/poster slots, registration 14th March!

We are pleased to announce that this year, the International Chemical Biology Society (ICBS) conference in joint with the ECBS (European Chemical Biology Symposium), will be at the Sorbonne Université in Paris, Oct 6 - 9! Stay tuned at: www.chemical-biology.org #chemicalbiology #ICBS2025 #ECBS2025

Amazing speaker lineup (Imperiali, Seeberger, Aye, Gonzalez Bello, Walport, Walport, Vendrell, Kele, Zeymer, Green, Thorn-Seshold, Biber) and beautiful venue - join us at #ESBOC58 in Gregynog/Wales on 28th-30th May for amazing #chembio and #bioorganic. Speaker/poster slots, registration 14th March!

We made a photoswitchable HaloTag (psHaloTag), which can reversibly turn-on fluorogenic dyes upon illumination 💡. Congrats to Franzi, Bego and all co-authors, check out our preprint below 👇 www.biorxiv.org/content/10.1...

I'm happy to see this paper I handled finally out! -- Directed evolution in mammalian cells using an orthogonal alphaviral RNA replication system with antiviral-induced mutagenesis #ChemBio #synbio www.nature.com/articles/s41...

This will be an exciting new collaboration with @drglycoben.bsky.social, Steve Sacks (KCL) & Subho Mukhopadhyay (KCL) Start date 3rd March 2025 or as soon as possible thereafter. www.jobs.ac.uk/job/DLA818/r...

That was a fantastic meeting, big shout-out to the Biochemical Society 😃 #glycotime!

Maybe a good time to plug this awesome book edited by former PhD students Howard Hang (Scripps), Matt Pratt (USC), Jenn Prescher (UC Irvine), featuring chapters by leaders in the field including @jeremybaskin.bsky.social and a forward by yours truly.

Trying to build a #proudofalumni list here on BlueSky. Here is a start, if others are here please reply so I can add you... @jeremybaskin.bsky.social @glycocode.bsky.social @nmriley.bsky.social @jcstark.bsky.social @raflynn5.bsky.social @pengwu.bsky.social ....

#Chembio crowd! Come and join #ESBOC25, the oldest Chemical Biology Symposium in Europe, in its 58th (!) instalment, on 28th-30th May 2025 - in beautiful and scenic Gregynog/Wales! Chaired by none other than Olalla Vazquez and with a rockstar lineup: www.esboc.org.uk

There is a German saying: "All good things come in three". Big congratulations to our third PhD graduate, Beatriz Calle! Bea has been a jointly supervised with Ilaria Malanchi and produced a fantastic story on using chemical biology to unravel protein glycosylation in breast cancer...

#SFG24 was so much fun - amazing #glycotime in a fantastic place. The right mix between talks by legends in the field and early career colleagues. Thank you to the organizers! I contributed our own story on xylosyltransferase bump-and-hole engineering, check here: www.biorxiv.org/content/10.1...

Super happy that our paper "Expanding the repertoire of GalNAc analogues for cell-specific bioorthogonal tagging of glycoproteins" has been published in RSC Chem. Biol. Led by Abdul Zafar funded by EPSRC and Vertex, and co-supervised by David Hewings. #glycotime! pubs.rsc.org/en/content/a...

Thank you to the RSC Chemical Biology Interface Community for the 2024 Norman Heatley Award! I am ever-grateful to my team, family, mentors and colleagues who make this research thing so much fun! Off to more #glycotime 😃 www.rsc.org/prizes-fundi...

EMBO Chemical Biology conference, join us in Heidelberg in September! Running since 2008, great event to learn about newest developments and to network. www.embl.org/about/info/c...

Shout-out to Dominika who is doing really important work to tackle the glycobiology of prostate cancer, funded by Prostate Cancer UK and integrated in the amazing network of the Institute of Chemical Biology at Imperial! @fuchtermatt.bsky.social

We made a new chemical tool to profile proteoglycans, one of the most important classes of glycoproteins! biorxiv.org/content/10.1... Led by Zhen Li with lots of input from Lucia Di Vagno, Anna Cioce and many more in an international collaboration! @thecrick.bsky.social

🥳🥳🥳 PhD done! Congratulations to Will Browne on his PhD defense *without corrections*!! Huge thanks to Gideon Davies and Alan Armstrong for being a fantastic examiner team. Just in time for the @thecrick.bsky.social Christmas party!

At lab Xmas lunch yesterday, we said goodbye in style to Dr Zhen Li who has been a fantastic team member for the last four years. All the best with your next steps! Then we embarked on an amazing scavenger hunt through the London Christmas lights.

Excited to share our latest results where we couple native glycoRNA labeling (rPAL) with DIA mass spec (SWATH-MS) and found that the RNA base acp3U is an attachment site for N-glycans in glycoRNA. Led by Axe+Helena w/Garcia+Bertozzi labs biorxiv.org/cgi/content/...

So proud of our PhD student Mia Zol-Hanlon who won the award for best presentation at the 89th Harden Conference in Proteoglycans! Here with Jerry Turnbull 😀 Glycotime!

Only a few days left to apply to our PhD position at the world-class Francis Crick Institute @thecrick.bsky.social, applying chemical tools to glycotime in the secretory pathway. Please forward to candidates, it is a great opportunity in an amazing environment! www.crick.ac.uk/careers-stud...

Cheers Hiren! Happy to have played a very small part in this story driven by Doug Sammon, Dave Briggs and Erhard Hohenester, in vitro reconstruction of the GAG biosynthetic pathway as a one-pot multienzyme reaction. #glycotime www.nature.com/articles/s41...

pubs.acs.org/doi/10.1021/... The next chapter in the saga of how human milk oligosaccharides shape immunity and curb infection. #glycotime

#glycotime people, if you’re already around here, I’m re-advertising my postdoc position in my group, so if you are keen on finding the golden path between biology and computing with me, come join us at CCG!