Want to know how lipidation of some nascent chains takes place by NMT2-- Check our latest work on how NAC couples Protein Synthesis with Nascent Polypeptide Myristoylation on the Ribosome out today @embojournal.org‬: www.embopress.org/doi/full/10....

Very cool study! also nicely complementing the recent selective ribosome profiling study from the Shu-ou Shan lab. I am intriguied what might be the proposed inhibitory mechanism shielding proteins from cotranslational insertion.

Emmanuel Levy @elevylab.bsky.social has joined BlueSky 🌟 with a fantastic Cell paper with Shu-ou Shan, showing the interactome of the TOM complex and how cotranslational mito import prioritizes large globular domains. Beautiful science! Give him a warm welcome 🎉 link: www.cell.com/cell/fulltex...

Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: www.biorxiv.org/content/10.1...

www.biorxiv.org/content/10.1... I am excited to share a big part of my thesis in preprint form, where we analysed the determinants of NAC-binding to translating ribosomes using selective ribosome profiling in C. elegans.

Last Friday I defended my PhD thesis. It was great day and I am so excited for what’s to come next!

NAC continues to deliver. What a fascinating protein!

News from the Lab! Congrats to everybody involved!

doi.org/10.1515/hsz-... I am super happy to share this review as my first post on Bluesky. After submitting my PhD thesis at the start of the year, my PI Elke Deuerling suggested to write this review with her, covering many of the findings of my thesis. I am excited to see it published today!