And to help, give up a minute a week to contribute to flusurvey.net

Glutamate is the primary molecule that neurons use to communicate with each other. Previously, scientists have mostly recorded when neurons fire output signals, but now with a new glutamate indicator, they can record the many inputs that causes cells to fire. 🧵 #neuroskyence

Four years ago, the red-light–activated channelrhodopsin #Chrimson restored basic vision in a blind patient. Here, we uncover its #multicolor_photoreactions and show implications for optogenetic applications. Many interesting details and a wonderful team🥳! www.pnas.org/doi/10.1073/...

If a key part of your job is getting information right and ferreting out falsehoods and untrustworthy sources, and the tool that’s supposed to help you do that keeps throwing you obvious errors, than yeah, you’re probably not going to *trust* it and may end up deciding it’s not all that useful.

This has been precisely my experience. I experimented a lot with ChatGPT for research-related work, summarizing, discovery, etc. The more I knew about a topic, the more errors and misleading assertions I saw in the bot’s outputs.

I keep having exactly this conversation with AI proponents: “I need it to be accurate.” “How accurate?” “100%” “Uh. How about 85%? Good enough?” “No, 100%.” “Well, we can’t do that because [reason of the week].” “Okay, talk to me when you can, then.”

TIL that the first incubators used to support preemies in the USA were a Coney Island sideshow. I honestly don't know how I feel about that. #preemie #fruehgeborene www.pbs.org/newshour/hea...

🔬📊 PhD (100%) – Statistics & ML for self-driving microscopy Joint PhD with David Ginsbourger (Stats) & Pertz Lab (Cell Biology). Gaussian Processes, Bayesian design, active learning on live-cell experiments. ohws.prospective.ch/public/v1/jo... #PhD #Statistics #MachineLearning #Bayesian

The 'Version of Record' of our paper came out on #FluorescenceFriday elifesciences.org/articles/105...

BonnBrain 2026 is officially sold out! Last admission decisions will be sent soon. Thank you for the overwhelming interest! We are looking forward to a fantastic meeting in Bonn next March.

I hate how much I enjoyed this BIG NERD DESIGN ENERGY 🫦

Here's a recap of Standard Notes in 2025 and what’s coming in 2026 🗒️ This year, we delivered 30+ fixes and improvements, and with support from Proton, Standard Notes has been strengthened without changing what makes it special. More in thread 👇 1/6

The experience of seeing Saturn’s rings for the first time with your own eyes is something, it really is. Or the Mars ice cap

Let me tell you a story. Perhaps you can guess where this is going... though it does have a bit of a twist. I was poking around Google Scholar for publications about the relationship between chatbots and wellness. Oh how useful: a systematic literature review! Let's dig into the findings. 🧵

Read yet another review today that ascribes GECIs' larger SNR vs GEVIs to their being evolved earlier (suggesting the GECIs are better optimized). This assumption is understandable but incorrect. GEVIs' photonic response per molecule per AP have been as good as GECIs since ASAP3.

One note here: if SNR / photon flux is limiting (as in most in vivo situations), imaging fast is a problem — I’m expanding on “if you can image fast”.

Ich habe in so kurzer Zeit eine fast körperliche Abneigung gegen diese mit AI erzeugten Eventflyer entwickelt, kann ich bitte die schlimmen selbstgebastelten Flyer mit Comic Sans noch mal sehen?

Inaugural lecture to the faculty of Yasin Dagdas (@plantophagy.bsky.social) and Simon Wiegert (@simwieg.bsky.social) - bridging green and red biology.

yeah, that’s weird. But if something goes wrong, you can try the one I’m using.

Join us for BonnBrain 2026! The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline. Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!

This experience is way too close to home. It is worth keeping close tabs on blood pressure when pregnant and knowing that swelling of fingers and in the face should not be dismissed as "normal for a summer pregnancy" without checking. Partners should have this on their radar as well.

An update of one of our papers has been posted to biorxiv. Stas, Yang, Schultz and Go, "Longitudinal three-photon imaging for tracking amyloid plaques and vascular degeneration in a mouse model of Alzheimer's disease". www.biorxiv.org/content/10.1...

A holiday demonstration of the different penetration depths of red and blue light into tissue. #optics

Not reassuring this early separation already in 2 days

Sorry @erictopol.bsky.social it doesn't. All participants were normal coffee drinkers. Therefore, the coffee-drinker arm is the Control arm. The intervention of going cold turkey increased the hazard of AF by 64% (100/0.61). The whole report is written from the wrong perspective.

70 teaspoons placed in tearooms around the institute & observed weekly over 5 months. 80% of spoons disappeared; spoon halflife~81 days. Communal room halflife lower than in specific labs. 250 spoons annually required to maintain 70 spoon population. pmc.ncbi.nlm.nih.gov/articles/PMC...

The annual course “Basics in Fluorescence Microscopy”, will be organised by the van Leeuwenhoek Centre for Advanced Microscopy from January 27th - 30th, 2026. Location: University of Amsterdam (NL) For more info, preliminary program and the application form check www.microscopycourse.nl?page_id=78

DeepEn is at NEUROSCIENCE 2025 #SfN25 ! 🧠🔬🌴 Come to our BOOTH #3027, check our microendoscope for deep brain imaging with sub cellular resolution and minimal tissue damage. And meet Hana, Tomas, Patrick and Jiri! #neuroimaging

Reposting this from #SfN25 in San Diego, where this collaboration takes off in fashion! 📣 🥳

Day 1 #SfN2025 exhibition has opened its doors. You can find @martinbrill.bsky.social and @swarnck.bsky.social with our friends from 89North and Chroma Technology Corp. at their both no. 2021. Come by and let's talk about your experiments and #photomanipulation from @rappopto.bsky.social

this goes right along with my theory that the AI obsession in *users* is often bc… 1. they were never educated (esp "ipad generation") & don't know how computers work 2. our tools and services are all SO AWFUL NOW, degraded at best, actively user-hostile at worst

@in-code.bsky.social Visit our Mini-Symposium 36 ‚Experience-driven dynamics in cortical inhibition for learning and behavior‘ - Room 6CF, November 19, 2025, 9:30 am at SFN, San Diego. Our speakers: Lisa Topolnik, Silvia da Silva, Linlin Fan, Attila Losonczy, Amar Sahay, Marlene Bartos.

We’re bringing our latest progress in neuromodulator imaging to #SfN2025! Don’t miss Dr. Li’s talk (Nov 19) and our lab’s posters (Nov 16). We look forward to connecting, exchanging ideas, and exploring collaborations. #neuroscience #neuroimaging #biosensors @sfn.org

Much was written & cited this past week on the Watson & Crick DNA paper-- which was a race-to-first, rather than an isolated insight. Who has made discoveries that have pushed science, technology, or medicine forward faster? Einstein, Curie, Nakamura, McClintock, Salk, Borlaug, etc. Who else?

I'm excited to join #SfN2025 next week. Stop by booth #3027 to connect and learn more about structural and functional imaging in-vivo anywhere in the brain! I’d love to hear about your research and ideas! Looking forward to meeting you there.

My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site #microscopy #ImageJ #FluorescenceFriday #microscopyMonday imagej.net/plugins/imag...

well, I'm biased... but i think absolutely! 😂 WAY more things in the database (like 1000s more). more FPs, dyes, filters from all providers. (The thermo viewer is primarily their own products). share/restore/download state. plus, it's open source, non-commercial, and accepts contribs try it? 👍

We are delighted to announce the Strathclyde Optical Microscopy Course 2026 (SOMC26), taking place in Glasgow from 21st July – 30th July 2026! Please find more details at shorturl.at/xmUiZ and apply at shorturl.at/MxTlI. Deadline 16 January 2026.

One of the most useful resources for anyone who uses fluorescence methods.

We are counting down the days until #SfN2025! Visit Thorlabs at booth # 2313 to explore our comprehensive line of imaging systems and voltage imaging technologies, designed to deliver high-performance and customizable solutions for your application’s needs.

The FPbase spectra viewer just had it's biggest software refactor in 6 years. It *should* be largely invisible to the end user (hopefully just faster and less buggy). Please let me know if you find any issues as you use it! www.fpbase.org/spectra/

Emerging trends of fluorescence lifetime imaging microscopy (FLIM): advances, challenges, and prospects www.biophysics-reports.org/article/doi/...

There are 2 articles in the Guardian: 1️⃣ stating that exhaustion is at EPIDEMIC levels 2️⃣ "The UK’s productivity crisis is one of the biggest challenges facing our economy and long-term health conditions in the workforce are a major factor in this" 🤦‍♀️Neither mentions #LongCovid

Very niche parenting advice: don't wear @thorlabs.bsky.social t-shirts during meals. The little dog is waaay more interesting than the bottle.

After SfN, on November 20, there is this conference in Irvine on imaging and mapping neural circuitry: cncm.medschool.uci.edu/2025-special...

If you would like to attend this course, but don't have funding, check our Microscopy Training Grants with @jcellsci.bsky.social to see if you are eligible. www.biologists.com/grants/jcs-f...

Okay so as promised... let's go through this paper and why it matters 🧵 #medsky #immunosky #idsky

Our team is hard at work preparing for #InsightFromImaging 2025! We can't wait to welcome HHMI #HannaGrayFellows to @hhmijanelia.bsky.social next week for lectures, hands-on labs, and activities focused on designing informative and quantitative bioimaging experiments 🔬

How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (@deisseroth.bsky.social) doi.org/10.1101/2025...