Happy weekend, you all!

Excited to share our latest paper - now out in @science.org - we showed how oxytocin modulates maternally-directed behavior in young mice (P15).

Led by the awesome @dzelmanoff.bsky.social

www.science.org/doi/10.1126/... From the one and only @oyiz.bsky.social lab

Thanks Jonas! PdCO was great to work with ☺️

Very nice work and use of PdCO for synaptic inhibition 😉 Congratulations 🎉

somehow missed this FLIM direct voltage paper www.biorxiv.org/content/10.1...

Lunar eclipse in 4 acts

Classic steel, new built, fun to ride. ❤️ 80's

Post an image from your summer that confers peace

Alps again

Seen in a restaurant

Voltage Imaging of CA1 Pyramidal Cells and SST+ Interneurons Reveals Stability and Plasticity Mechanisms of Spatial Firing https://www.biorxiv.org/content/10.1101/2025.08.20.671230v1

How your email finds me!

I'm more than psyched to share that my PhD paper is now out in Neuron! It's also my first paper as both first author and corresponding author, which means even more to me! Thank my partner Chi-Chieh for her contribution to the most adorable ever graphic abstract 🥰

Hurray 🥳 Waiting for another 220 citations

Nice www.nature.com/articles/s41... Still red green pics, why @natureportfolio.nature.com ?

More Alps

Alps, great.

My way up

#OCaMP is now on bioRxiv and reagents are available on #Addgene! 🧪 A sensitive orange fluorescent calcium ion indicator for imaging neural activity www.biorxiv.org/content/10.1...

At the spinning disc... listening to "...baby one more time" 😄

Opsin 5 mediates violet light-accelerated wound healing in mammalian corneas www.cell.com/cell-reports...

What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope! Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals. Read the paper here: www.science.org/doi/10.1126/... (1/10)

Figure 3

My daughter's classmate is suffering from aggressive neuroblastoma. If you'd like to help and make a CAR-T cell therapy possible, please go to: www.gofundme.com/f/hoffnung-f... Thank you 🙏

Probably useful 😉 🧪🧠

New plasmids available from the @massecklab.bsky.social‬! PinkyCaMP, a mScarlet-based calcium sensor, can be leveraged for its exceptional brightness, photostability, and multiplexing capabilities. https://twp.ai/4iobS2

Every big grant I applied for was turned down with the argument that it is too exploratory.

Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine www.science.org/doi/10.1126/...

The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology. Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at [email protected]. Fee waivers and bursaries available. ! Please share widely !

Some will be back in the game again.

It is out! Read how you achieve 1.7 mm deep 3-photon imaging in prefrontal cortex with dendritic spine resolution over a week. www.nature.com/articles/s42...

Um 17 Uhr heißt es

RIP. I still miss you, dad 💔. 14 years can't change that.

My favorite blue, cornflower.

While I applaud Europe taking a step to fund bringing scientific excellence to Europe, the ERC’s current success rates at 10% for Europe based scientists is statistically at lottery levels. The total ERC budget should double across the board aiming at doubling funding rates.

If you see this, post the most recent photo of yourself from your camera roll. No cheating!

More PdCO

I'd like to share a little bit of happy lab news in these chaotic times: a new preprint, driven by the brilliant Qinhao Cao! www.biorxiv.org/content/10.1... We address a big challenge in synbio: If you give me a protein "X", how can I give you a version of X whose activity is controlled by a kinase?

Join us this Monday and Tuesday 28 - 29 April 2025 for the 1st Paris Circuit Dynamics Conference on Hippocampal–Cortical Circuits at the @institutducerveau.bsky.social Limited spots available, so please register (it's free)! 14 invited speakers 8 contributed talks 32 posters www.paris-circuits.eu

My lab has several postdoctoral fellow and software engineering positions available. Please email me if you’re interested.

We’re hiring! The Masseck Lab (University of Cologne) is looking for a full-time Technical Assistant (permanent position). Focus: neuroscience, behavior experiments, and cell culture. Apply by May 1st → jobportal.uni-koeln.de/ausschreibun... #JobAlert #Neuroscience #LabTech #BTA #UniCologne

just Alps

Which synapses get stronger when we form a memory? We developed a technique to tag recently potentiated synapses in live mice. Pulse-chase labeling with membrane-impermeable HaloLigand dyes distinguishes fresh AMPA receptors from old ones. www.nature.com/articles/s41...

www.biorxiv.org/content/10.1... with mouseline, needs PCB injection.

Timeline cleanser

Axolotls in your timeline!

What a week, first GluSnFR4 and now GABASnFR2👏