Really cool stuff! Engineered excitatory opsins responding to 15nW light

Breaking a hiatus to post this. A group of Israeli Social Psychologists, myself included, wrote a letter to speak out clearly against the Israeli government’s decisions and the resulting devastation in Gaza. docs.google.com/document/d/1... In hopes of peace and safety for all, and soon

Very cool study by @oyiz.bsky.social using optogenetics to shed light on how oxytocin signaling regulates vocalization to maintain maternal bonds (with nice write-up by @bellonec.bsky.social, “Cries into ties” indeed) 🧪 www.science.org/doi/10.1126/...

Excited to share our latest paper - now out in @science.org - we showed how oxytocin modulates maternally-directed behavior in young mice (P15).

In the past year and a half, we have been intensively protesting and fighting the Israeli government in an attempt to stop the war, secure the release of all hostages, and prevent the ongoing humanitarian crisis. Until now, our protests have primarily been focused internally.

What time is it? ⏰ Time to talk about the brain! 🧠 Opening the Neurotechnologies plenary session is @oyiz.bsky.social of Weizmann Inst. of Science. He is discussing new tools that allow highly light-sensitive silencing AND facilitate spectral multiplexing for modulation + imaging. #PhotonicsWest

First post on Bluesky!✨ (1/7) Far-red dopamine sensor is coming! Excited to introduce our chemigenetic DA sensor, HaloDA1.0! #Dopamine #FarRedSensors, #GRAB www.biorxiv.org/content/10.1...

Optogenetics 7.0 🍾 Cheers 🥂 @johvierock.bsky.social @oyiz.bsky.social @deisseroth.bsky.social

Neuroscience students asked us to teach a PRACTICAL course on experimental methods, and it is now on YouTube! Please like and repost to help us get the word out! www.youtube.com/playlist?lis... Lecture 1: Signals and data acquisition Focusing on hardware, digital/analog I/O, synchronization 🧵

Related to this, I created a starter pack for those interested/involved in Epilepsy research. Many of the DBS folks may also be interested. go.bsky.app/B8pPi1n

Upon popular demand I created a started pack for people interested in Deep Brain Stimulation! Lmk if you'd like to be added! go.bsky.app/B9A9Cho

How to rebuild your network on @bsky.app and improve your experience here? I made a short starter guide with resources. www.neuronaldynamics.eu/resources/bl... Also, a thread 🧵 below.

One difference is that the DIO approach leads to the permanent removal of DNA, making it irreversible. For SIO an equilibrium between forward and reverse recombinantion is created. However the reverse probability is low, creating a bias to the activated state. In practice expression levels are good.

Important paper! www.biorxiv.org/content/bior... Im not sure the Discussion fully delineates its radical implications. No more... * Place cells * Grid cells, splitter cells, border cells * Mirror neurons * Reward neurons * Conflict cells (continued)

A moment in time: Dieter Oesterhelt passed away in Münich on this day (November 28) in 2022. He identified the 1st microbial rhodopsin more than 50 years ago, with far-reaching impact that could hardly have been imagined. laskerfoundation.org/in-memoriam-...

Many people have asked me what's the deal with "SIO" in our Addgene vectors (www.addgene.org/Ofer_Yizhar/) - we use these in most of our Cre-dependent AAVs - so here's a brief explanation of how it works.

PdCO has now been distributed 100x via @addgene.bsky.social 🥳🥳🥳🙏🙏🙏

Announcing a new open access textbook for entry level behavioral neuro. Funded by NSF. Written by a collection of 26 neuro experts. Method demonstration videos and author interviews too. Consider using it in your courses to reduce financial barriers to education. openstax.org/details/book...

We’re seeking a postdoc/student excited about animal communication, brain-wide circuits, microscopy, singing fish (Danionella), wacky ideas and who likes to: get things done, experiment, analyze, ask, learn, help and cooperate. jlab.berlin

Hello bluesky please accept this offering of a picture from my recent run with @franklandlab.bsky.social