You have no idea how proud I am of of this paper from the lab showing that RANK signalling affects the development of Tuft and BEST4 cells in the zebrafish gut, with in vivo evidence indicating that BEST4 cells contribute to defences against enteropathogens

Both caffeinated and decaf coffee altered gut bacteria in ways linked to better mood and lower stress. Decaf even improved learning and memory, while caffeine boosted focus and reduced anxiety.

Back in Alicante with my partner because I enjoyed it for @edrc2025.bsky.social so much! 🇪🇸

(3/15) Eels are basal teleosts with elongated bodies. Many species have massively expanded vertebral counts (Japanese eel: 120 vertebrae). The Aulehla Lab studies somitogenesis — the embryonic process that gives rise to vertebrae — and we wanted to understand how this unfolds in eels.

Beyond delighted to share our amazing collaboration with Thierry Alquier's lab @alquierthierry.bsky.social on a conserved role for neuronal lipid droplets in regulating energy homeostasis in vivo led by Celena Cherian, Romane Manceau, Danie Majeur, and Colin Miller www.nature.com/articles/s42... /1

Glad the BBC are prioritising the most important global stories on the front page this morning.

Why do people respond differently to GLP-1 weight-loss drugs? Genetics has the answer - provided in this genome wide association study led by @adamauton.bsky.social www.nature.com/articles/s41... 🧪 www.nature.com/articles/d41...

Well thats awkward www.cell.com/cell-reports...

Like #hemocytes? I'm advertising a 3 year, BBSRC #postdoc position, in #Edinburgh, using #Drosophila & human cells to understand sex differences in the regulation of #macrophage function, an exciting collaboration with the Bénézech and Wood labs. Please share! 🪰🏴󠁧󠁢󠁳󠁣󠁴󠁿 www.jobs.ac.uk/job/DQU604/p...

Netanyahu: ‘These So-Called Genocide Experts Have Probably Never Committed A Genocide In Their Lives’ https://theonion.com/netanyahu-these-so-called-genocide-experts-have-probably-never-committed-a-genocide-in-their-lives/

Hegseth has admitted that America has *no interest* in "fighting fair." And what it did to that warship near India was an obvious war crime; even the Nazis rescued drowning sailors. So one would have to be naive to say the US-IDF alliance "wouldn't" issue strategic drone strikes.

Thirty-six solutions to stabilize Earth’s climate | Science www.science.org/doi/10.1126/... 🧪

My paper on how the fruit fly foregut uses a modified cell cycle to respond to tissue damage and cell loss is now published :) www.nature.com/articles/s41... #proventriculus #drosophila

'I didn't grow up wanting to be a politician, I'm a plumber' The green Party's Hannah Spencer has won the Gorton and Denton, with Reform in second and Labour finished third

First bike to work without a coat this year! (Also whats that weird colour in the sky???)

Job alert! 📣 I’m looking for a research assistant to join my new team @idrm.ox.ac.uk Were using #zebrafish to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️‍🩹 Full info below, and please share! 🫶🏻 bit.ly/467TO0M

Have a look at our latest preprint, "Nuclear plasticity regulates macrophage phagocytic capacity in vivo". #apoptoticbodies #efferocytosis #nucleus #Drosophila #macrophages #mechanoresponse #InVivo #LiveImaging doi.org/10.64898/202...

Amazing city, even better lab!

Aaand... my first cover!! RpS6 phosphorylation (magenta) in a Udd (ribosome biogenesis factor) mutant ovary 🔬

🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! 🐣🔬 This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share! www.findaphd.com/phds/project... 🧪

@senapati.bsky.social latest and greatest! Charly Treiber on board too. Over and out. www.biorxiv.org/content/10.1...

AWS is down, post hog

Scientists just found several fossil bumblebees covered in pollen that directly matches fossil flowers nearby. The 24-million-year-old discovery reveals the oldest known evidence connecting pollinators to the pollinated. #Paleontology #NationalFossilDay 🧪🏺 New at @sciencenews.bsky.social

Happy to share the last version of our story @currentbiology.bsky.social on the role of interfacial tension in mechanical cell competition led by @leovalon.bsky.social and Alexis Matamoro Vidal www.sciencedirect.com/science/arti...

John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died. Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology. More: www2.mrc-lmb.cam.ac.uk/john-gurdon-... #LMBNews

Bloody lovely www.bbc.co.uk/news/live/cy...

Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...

I wrote something on developmental biology and disability and put it up on the node last night: thenode.biologists.com/developmenta... I've been nervous to share because some of it veers a bit personal but they are thoughts that won't stay quiet. Would love to know what people think about it!

Some amazing talks but highlights for me were David Bilder on innate immune-tumour interactions, @jackholcombe.bsky.social ‘s PhD prize tour de force and exciting and beautiful data and new tools to look at basement membrane and clotting hot out of @stramerlab.bsky.social

Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia. Open access link below: www.nature.com/articles/s41... Here's a cool animated summary

Such an amazing experience sharing science with a wonderful community! Thanks so much 🧬🔬@edrc2025.bsky.social @fly-eds.bsky.social

This is the organizing team behind #EDRC2025 María Dominguez, Javier Morante @morantelab.bsky.social , Juan Sanchez-Alcaniz @sanchezalcaniz.bsky.social , Pepe Pastor-Pareja @pastorparejalab.bsky.social and Ana Carmena

We are loving the @edrc2025.bsky.social !! Please come find us at the poster sessions and coffee breaks!

If you find yourself at @edrc2025.bsky.social please check my wonderful postdoc's talk @neurogut.bsky.social at the gut workshop this afternoon. Gut, sex, reproduction, our new story! In combo with @irenemiguel-aliaga.bsky.social! @fly-jedi.bsky.social #EDRC2025

This is great news. Though 'reviewed preprints" does feel a bit dated by now. Last year a few people asked me why EMBO still only accepted reviewed preprints.

“Trump's Harvard cuts threaten a giant in the biomedical research community: A database about the tiny fruit fly” The FlyBase grant is run through the Perrimon lab at HMS, so when Trump cut off 100% of our NIH $, it causes existential risk to the entire community www.nbcnews.com/science/scie...

Specifically on the #metascience side, congrats to @josephlemaitre.bsky.social and @brunolemaitre.bsky.social on this consequential piece. 🎉 By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.

🔬New paper! This has been my personal favorite project I’ve ever done - also, the only one that the President has been relentlessly trying to destroy by 100% defunding our lab & institution. Please enjoy: www.biorxiv.org/content/10.1...

Calling all meeting organizers… @biologists.bsky.social now have a calculator to estimate your event’s carbon footprint and to test various reduction scenarios. thenode.biologists.com/event-carbon...

🎉Excited to share our latest paper, published in Nature Communications!🎉 "Enhancing autophagy by redox regulation extends lifespan in Drosophila" #redox #metabolism #ageing #Drosophila @natcomms.nature.com @mrc-lms.bsky.social doi.org/10.1038/s414...

So honoured to receive this prize! Really looking forward to EDRC!

Congratulations to @jackholcombe.bsky.social for his #EDS best PhD thesis award! Jack will give a plenary talk at #EDRC2025

✨️ Come join my lab! ✨️ I have an ARUK funded post doc position available for a talented ECR to work with Drosophila and human iPSC derived neurons. krb-sjobs.brassring.com/TGnewUI/Sear...

We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.

Many cells during development are exposed to caspase activation and yet survive. Why some die and not others ? We found out that the memory of previous caspase activation bias significantly later death comitment and bias death distribution and single cell decision www.biorxiv.org/content/10.1...

The mechanisms & regulation of insect #antimicrobialpeptides & #HDPs is of wide interest. We now appreciate their function in vivo is much more complex than what's described in vitro. Our primer on insect AMP regulation, evolution & function. Pub: doi.org/10.1016/B978... 🟩OA: bit.ly/MHLH2025 1/n

If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social

We are delighted to announce that the winner of the 2025 Waddington Medal is Helen Skaer! bsdb.org/2025/03/25/2...

Check out these feather buds on the chicken embryo's wing! Our latest study @plosbiology.org reveals that temporary inhibition of sonic hedgehog signalling transforms feathers into simple, protofeather-like structures—similar to those of their dinosaur ancestors🔬🦖🧪 journals.plos.org/plosbiology/...

Do you need some science joy in your life? Do you like neurons? Maybe glia? Molecules? Cell biology? Save the date for #NeuroBioUK25 - the venue is booked and we are excited to see you and your incredible science there on the 12th of September! neurobiouk.sites.sheffield.ac.uk